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6篇 您的检索式:作者名="Sarah Barrett"
    题名 作者 年代 出处 被引量
1Over-expression of sphingosinekinase-1 enhances a progenitor phenotype in humanendothelial cells显示文摘Barrett Jeffrey M Parham Kate A Pippal Jyotsna B CockshellMichaelia P Moretti Paul A B Brice Sarah L Pitson StuartM Bonder Claudine S 2011Microcirculation2011,187,:1
2An examination of the factors that influence costs in medical patients with health anxiety显示文摘Barbara Barrett Peter Tyrer Helen Tyrer Sylvia Cooper Mike J. Crawford Sarah Byford 2012Journal of Psychosomatic Research2012,,1:1
3Nationwide retrospective study of hepatitis B virological response and liver stiffness improvement in 465 patients on nucleos(t)ide analogue显示文摘BACKGROUND Hepatitis B virus(HBV)nucleos(t)ide analog(NA)therapy reduces liver disease but requires prolonged therapy to achieve hepatitis B surface antigen(HBsAg)loss.There is limited North American real-world data using non-invasive tools for fibrosis assessment and few have compared 1st generation NA or lamivudine(LAM)to tenofovir disoproxil fumarate(TDF).AIM To assess impact of NA on virological response and fibrosis regression using liver stiffness measurement(LSM)(i.e.,FibroScan®).METHODS Retrospective,observational cohort study from the Canadian HBV Network.Data collected included demographics,NA,HBV DNA,alanine aminotransferase(ALT),and LSM.Patients were HBV monoinfected patients,treatment naïve,and received 1 NA with minimum 1 year follow-up.RESULTS In 465(median 49 years,37%female,35%hepatitis B e antigen+at baseline,84%Asian,6%White,and 9%Black).Percentage of 64(n=299)received TDF and 166 were LAM-treated with similar median duration of 3.9 and 3.7 years,respectively.The mean baseline LSM was 11.2 kPa(TDF)vs 8.3 kPa(LAM)(P=0.003).At 5-year follow-up,the mean LSM was 7.0 kPa in TDF vs 6.7 kPa in LAM(P=0.83).There was a significant difference in fibrosis regression between groups(i.e.,mean-4.2 kPa change in TDF and-1.6 kPa in LAM,P<0.05).The last available data on treatment showed that all had normal ALT,but more TDF patients were virologically suppressed(<10 IU/mL)(n=170/190,89%)vs LAM-treated(n=35/58,60%)(P<0.05).None cleared HBsAg.CONCLUSION In this real-world North American study,approximately 5 years of NA achieves liver fibrosis regression rarely leads to HBsAg loss.Alnoor Ramji Karen Doucette Curtis Cooper Gerald Yosel Minuk Mang Ma Alexander Wong David Wong Edward Tam Brian Conway David Truong Philip Wong Lisa Barrett Hin Hin Ko Sarah Haylock-Jacobs Nishi Patel Gilaad G Kaplan Scott Fung Carla S Coffin 2022World Journal of Gastroenterology2022,28,31:1
4Ethnic Differences in Insulin Resistance and Body Composition in United Kingdom Adolescents显示文摘Sarah Ehtisham Nicola Crabtree Penelope Clark Nick Shaw Timothy Barrett 2005The Journal of Clinical Endocrinology & Metabolism2005,,:1
5The Data Visualisation and Immersive Analytics Research Lab at Monash University显示文摘This article reviews two decades of research in topics in Information Visualisation emerging from the Data Visualisation and Immersive Analytics Lab at Monash University Australia(Monash IA Lab).The lab has been influential with contributions in algorithms,interaction techniques and experimental results in Network Visualisation,Interactive Optimisation and Geographic and Cartographic visualisation.It has also been a leader in the emerging topic of Immersive Analytics,which explores natural interactions and immersive display technologies in support of data analytics.We reflect on advances in these areas but also sketch our vision for future research and developments in data visualisation more broadly.Tim Dwyer Maxime Cordeil Tobias Czauderna Pari Delir Haghighi Barrett Ens Sarah Goodwin Bernhard Jenny Kim Marriott Michael Wybrow 2020Visual Informatics2020,4,4:0
6Recovery of threatened plant species and their habitats in the biodiversity hotspot of the Southwest Australian Floristic Region显示文摘The Southwest Australian Floristic Region(SWAFR) is a global biodiversity hotspot with high plant diversity and endemism and a broad range of threatening processes. An outcome of this is a high proportion of rare and threatened plant species. Ongoing discovery and taxonomic description of new species, many of which are rare, increases the challenges for recovery of threatened species and prioritisation of conservation actions. Current conservation of this diverse flora is based on integrated and scientific evidence-based management. Here we present an overview of current approaches to the conservation of threatened flora in the SWAFR with a focus on active management through recovery and restoration that is integrated with targeted research. Key threats include disease, fragmentation, invasive weeds, altered fire regimes, grazing, altered hydro-ecology and climate change. We highlight the integrated approach to management of threats and recovery of species with four case studies of threatened flora recovery projects that illustrate the breadth of interventions ranging from In situ management to conservation reintroductions and restoration of threatened species habitats. Our review and case studies emphasise that despite the scale of the challenge, a scientific understanding of threats and their impacts enables effective conservation actions to arrest decline and enhance recovery of threatened species and habitats.Leonie Monks Sarah Barrett Brett Beecham Margaret Byrne Alanna Chant David Coates J.Anne Cochrane Andrew Crawford Rebecca Dillon Colin Yates 2019Plant Diversity2019,41,2:0
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