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| 1 | Crohn's disease environmental factors in the developing world: A case-control study in a statewide catchment area in Brazil显示文摘AIM To identify environmental risk factors associated with the development of Crohn's disease(CD) in order to reassess the hygiene hypothesis.METHODS A hospital-based, case-control study was carried out with CD patients(n = 145) and controls(n = 163)representing a socioeconomically diverse statewide catchment area in Brazil. Controls were recruited from caregivers of patients seen in different outpatient clinics at the same hospital. A multi-item survey with 94 questions regarding family history of CD, perinatal and childhood circumstances, living conditions, tobacco use and familial socioeconomic status was carried out by interviewers. RESULTS On the univariate analysis, predictive variables for CD included being male, under age of 40, a high education level, urban dweller, smaller family size, exposure to enteric pathogens and user of treated water(P < 0.005). On the multivariate analysis, variables significantly associated with CD were male gender(OR = 2.09), under age 40(OR = 3.10), white(OR = 2.32), from a small family in childhood(OR = 2.34) and adulthood(OR = 3.02), absence of viral infections in childhood(OR = 2.23), exposure to enteric pathogens(OR = 2.41), having had an appendectomy(OR = 2.47) and prior or current smoker(OR = 2.83/1.12). CONCLUSION Most variables supporting the 'hygiene hypothesis' are associated with the development of CD but are not independent predictors of the diagnosis. | Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Boechat Bianca C Schorr Isabella S Leao Tiago Nunes Cyrla Zaltman | 2017 | World Journal of Gastroenterology2017，23，30： | 2 |
| 2 | Laparoscopy-assisted versus open colectomy for treatment of colon cancer in the elderly: morbidity and mortality outcomes in 545 patients显示文摘 | Francesc Vallribera Valls Filippo Landi Eloy Espín Basany José Luis Sánchez García Luis Miguel Jiménez Gómez Marc Martí Gallostra Luis Salgado Cruz Manuel Armengol Carrasco | 2014 | Surgical Endoscopy2014，，12： | 2 |
| 3 | Inhibitory action of aqueous coffee ground extracts on the corrosion of carbon steel in HCl solution显示文摘 | Vanessa Vasconcelos Torres Roberto Salgado Amado Camila Faia de Sá Tatiana Lopez Fernandez Carlos Alberto da Silva Riehl Alexandre Guedes Torres Eliane D’Elia | 2011 | Corrosion Science2011，，7： | 1 |
| 4 | Liver cirrhosis is reverted by urokenase-type plasminogen activator gene therapy显示文摘 | Salgado S Garcia J Vera J | 2000 | Mol Ther2000，2，6： | 1 |
| 5 | Liver cirrhosis is reverted by urokinase-type plasminogen activator gene therapy显示文摘 | Salgado S Garcia J Vera J | 2000 | Mol Ther2000，2，： | 1 |
| 6 | Liver cirrhosis is reverted by urokinase-type plasminogen activator gene therapy显示文摘 | Salgado S Garcia J Vera J | 2007 | Mol Ther2007，2，6： | 1 |
| 7 | Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial 显示文摘 | Loi S Michiels S Salgado R | 2014 | Ann Oncol2014，25，8： | 1 |
| 8 | Bearing capacity of circular footings under surcharge using state-dependent finite element analysis 显示文摘 | LEE J SALGADO R KIM S | 2005 | Computers and Geotechnics2005，32，： | 1 |
| 9 | Transmission loss allocation through a modified Y-bus显示文摘 | Daniel J S Salgado R S Irving M R | 2005 | lEE Proceedings-Generation Transmission andDistribution2005，152，2： | 1 |
| 10 | Limit analysis versus limit equilibrium for slope stability显示文摘 | Yu H S Salgado R Sloan S W | 1998 | J Geotech and Geoenvir Engrg ASCE1998，124，1： | 1 |
| 11 | Effects of late loss of arterial inflow on free flap survival 显示文摘 | Salgado CJ Smith A Kim S | 2002 | J Reconstr Microsurg2002，18，7： | 1 |
| 12 | Treatment ofauricular pseudocyst with aspiration and local pressure显示文摘 | Salgado C J Hardy J E Mardini S | 2006 | J Plast Reconstr Aesthet Surg2006，59，12： | 1 |
| 13 | Power flow solutions through tensor methods显示文摘 | Salgado R S Zeitune A F | 2009 | IET Generation Transmission & Distri- bution2009，3，5： | 1 |
| 14 | Limit analysis of soil slopes subjected to pore water presures显示文摘 | Salgado R Yu H S | 1999 | Journal of Geotechnical Engineering1999，125，1： | 1 |
| 15 | Two- and three-dimensional bearing capacity of footings in sand显示文摘 | Lyamin A V Salgado R Sloan S W and Prezzi M | 2007 | Geotechnique2007，57，8： | 1 |
| 16 | The importance of nerve terminal deploarization in pyrethriod poisoning of insects显示文摘 | Salgado V L Iriving S N Miller T S | 1983 | Pestitic Biochem Physiol1983，20，： | 1 |
| 17 | LimitAnalysis Versus Limit Equilibrium for Slope Stability 显示文摘 | YU H S SALGADO R SLOAN S W | 1998 | Journal of Geotechnical and GeoenvironmentalEngineering1998，124，1： | 1 |
| 18 | Latitudinal variation in palatability ofsalt-marsh plants:are differences constitutive?显示文摘 | Salgado C S Pennings S C | 2005 | Ecology2005，86，： | 1 |
| 19 | Limit analysis versus limit equilibrium for slope stability显示文摘 | YU H S SALGADO R SLOAN S W | 1998 | Journal of Geotechnical and Geoenvironment Engineering ASCE1998，124，1： | 1 |
| 20 | Antimicrobial activity of D-3-phenyllactic acid produced by fedbatch process against Salmonella enterica显示文摘 | Rodriguez N Salgado J M Cortes S | 2012 | Food Control2012，25，1： | 1 |
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