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| 1 | Current systematic reviews and meta-analyses of COVID-19显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)has left a significant impact on the world's health,economic and political systems;as of November 20,2020,more than 57 million people have been infected worldwide,with over 1.3 million deaths.While the global spotlight is currently focused on combating this pandemic through means ranging from finding a treatment among existing therapeutic agents to inventing a vaccine that can aid in halting the further loss of life.AIM To collect all systematic reviews and meta-analyses published related to COVID-19 to better identify available evidence,highlight gaps in knowledge,and elucidate further meta-analyses and umbrella reviews that are yet to be performed.METHODS We explored studies based on systematic reviews and meta-analyses with the keyterms,including severe acute respiratory syndrome(SARS),SARS virus,coronavirus disease,COVID-19,and SARS coronavirus-2.The included studies were extracted from Embase,Medline,and Cochrane databases.The publication timeframe of included studies ranged between January 01,2020,to October 30,2020.Studies that were published in languages other than English were not considered for this systematic review.The finalized full-text articles are freely accessible in the public domain.RESULTS Searching Embase,Medline,and Cochrane databases resulted in 1906,669,and 19 results,respectively,that comprised 2594 studies.515 duplicates were subsequently removed,leaving 2079 studies.The inclusion criteria were systematic reviews or meta-analyses.860 results were excluded for being a review article,scope review,rapid review,panel review,or guideline that produced a total of 1219 studies.After screening articles were categorized,the included articles were put into main groups of clinical presentation,epi-demiology,screening and diagnosis,severity assessment,special populations,and treatment.Subsequently,there was a second subclassification into the following groups:gastrointestinal,cardiovascular,neurological,stroke,thrombosis,anosmia and dysgeusia,ocular manifestations,nephrology,cutaneous manifestations,D-dimer,lymphocyte,anticoagulation,antivirals,convalescent plasma,immunosuppressants,corticosteroids,hydroxychloroquine,renin-angiotensin-aldosterone system,technology,diabetes mellitus,obesity,pregnancy,children,mental health,smoking,cancer,and transplant.CONCLUSION Among the included articles,it is clear that further research is needed regarding treatment options and vaccines.With more studies,data will be less heterogeneous,and statistical analysis can be better applied to provide more robust clinical evidence.This study was not designed to give recommendations regarding the management of COVID-19. | Mahmoud Nassar Nso Nso Mostafa Alfishawy Anastasia Novikov Salim Yaghi Luis Medina Bahtiyar Toz Sofia Lakhdar Zarwa Idrees Yungmin Kim Dawa Ongyal Gurung Raheel S Siddiqui David Zheng Mariam Agladze Vikram Sumbly Jasmine Sandhu Francisco Cuevas Castillo Nadya Chowdhury Ravali Kondaveeti Sakil Bhuiyan Laura Guzman Perez Riki Ranat Carlos Gonzalez Harangad Bhangoo John Williams Alaa Eldin Osman Joyce Kong Jonathan Ariyaratnam Mahmoud Mohamed Ismail Omran Mariely Lopez Akwe Nyabera Ian Landry Saba Iqbal Anoosh Zafar Gondal Sameen Hassan Ahmed Daoud Bahaaeldin Baraka Theo Trandafirescu Vincent Rizzo | 2021 | World Journal of Virology2021，10，4： | 2 |
| 2 | Bio-synthesized palladium nanoparticles using alginate for catalytic degradation of azo-dyes显示文摘Palladium nanoparticles(PdNPs)were synthesized in a green way using sodium alginate functioning as both reductant and stabilizer.The formation of as-synthesized Pd NPs was supervised by Ultraviolet–visible(UV–Vis)spectroscopy and confirmed by the surface plasmon resonance(SPR)band.The effect of several synthesis factors such as precursor ratio,solution p H,reaction time,and temperature were investigated by the factorial design of experiments in order to optimize the experimental conditions.The optimal synthesis parameters were achieved by heating 1.0 ml of 1.0%sodium alginate(SA),3.0 ml of 10-2 mol·L-1 H2PdCl4 at 80°C for a period of 30 min in a neutral reaction medium(pH=6).High-resolution transmission electron microscope(HRTEM),energy dispersive X-ray(EDX)spectroscopy,selected area electron diffraction(SAED)pattern,X-ray powder diffraction(XRD),and dynamic light scattering(DLS)were used to confirm the uniform spherical shapes and high crystallinity of Pd NPs with average particle size of(2.12±1.42)nm.The SEM images show the distribution of Pd NPs presented among the SA.FTIR spectra indicate that SA is a good capping agent to stabilize Pd NPs for a long time.The catalytic degradation of model azo-dyes such as mono-azo(Cibacron Yellow FN–2R)and di-azo(Cibacron Deep Red S–B)were confirmed the catalytic activity of Pd NPs.The Pd NPs can accelerate the degradation rate by more than 80 and 10 times respectively as confirmed by kinetics constant(k)values. | Yi Xiong Liping Huang Sakil Mahmud Feng Yang Huihong Liu | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 1 |
| 3 | TAp73 suppresses repression of proangiogenic cytokines and HIF-la activity 显示文摘 | Stantic M Sakil HA Zirath tumor angiogenesis through H | 2015 | Proc Natl Acad Sci USA2015，112，1： | 1 |
| 4 | Breast Milk Is Better Than Formula Milk in Preventing Parenteral Nutrition–Associated Liver Disease in Infants Receiving Prolonged Parenteral Nutrition显示文摘 | Sakil Kulkarni Velma Mercado Mirta Rios Richard Arboleda Roberto Gomara William Muinos Jesse Reeves-Garcia Erick Hernandez | 2013 | Journal of Pediatric Gastroenterology and Nutrition2013，，3： | 1 |
| 5 | TAp73 suppresses tumor angio-genesis through repression of proangiogenic cytokines and HIF-la ac-tivity显示文摘 | Stantic M Sakil HA Zirath H | 2015 | Proc Natl Acad Sci USA2015，112，1： | 1 |
| 6 | Liver transplantation during global COVID-19 pandemic显示文摘The coronavirus disease 2019(COVID-19)caused by severe acute respiratory disease respiratory syndrome coronavirus-2 has significantly impacted the health care systems globally.Liver transplantation(LT)has faced an unequivocal challenge during this unprecedented time.This targeted review aims to cover most of the clinical issues,challenges and concerns about LT during the COVID-19 pandemic and discuss the most updated literature on this rapidly emerging subject. | Mostafa Alfishawy Nso Nso Mahmoud Nassar Jonathan Ariyaratnam Sakil Bhuiyan Raheel S Siddiqui Matthew Li Howard Chung Amira Al Balakosy Ahmed Alqassieh Tibor Fülöp Vincent Rizzo Ahmed Daoud Karim M Soliman | 2021 | World Journal of Clinical Cases2021，9，23： | 0 |
| 7 | Numerical investigation of tunneling induced surface movement:A case study of MRT line 1,Dhaka显示文摘The proposed underground tunnel for Mass Rapid Transit Line 1,Dhaka brings immense attention to the engineers and experts not only because of its construction challenges through a densely-built city,but also for the potential tunneling-induced ground settlements.This very preliminary study investigates the ground surface movement due to the progression of the tunnel boring machine(TBM)using numerical analysis.A series of finite element(FE)models have been developed using PLAXIS 3D,in which Mohr–Coulomb(MC),modified Cam-Clay(MCC),and hardening soil(HS)have been considered.The in-field data of Mashhad Metro Line-2 have been compared to verify PLAXIS 3D’s efficacy in tunnel modeling.Subsequently,the outcomes of the FE analyses are compared with the existing empirical formulas.The PLAXIS 3D analysis considering the MCC soil model exhibits strong agreement with the real monitored data,with a variance of only 3.85%.After simulating different stages of the tunnel construction,results are reported in terms of the distance of the inflexion point from the center,the settlement trough pattern,the maximum transverse settlements,and the vertical settlements.They are also compared with the established empirical formula.In order to comprehend the surface settlement with various tunnel depths and diameters,a parameter dependency study has been carried out.The analysis findings showed that increasing the TBM’s depth and radius causes the inflexion point’s distance from the center of the tunnel to increase by 4%and decrease by 5%,respectively.It is also observed that as tunnel depth increases,the overall settlement of the tunnel lowers by 11%for every additional 5 meters of depth.The MCC model,out of the three,exhibits the most accurate value of the settlement compared to that obtained from the empirical solutions,and also the best-fit form to the Gaussian curve. | Khondaker Sakil Ahmed Johana Sharmin Mehedi Ahmed Ansary | 2023 | Underground Space2023，，5： | 0 |
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