维普期刊资源整合服务平台（V6.5）

54篇 您的检索式：作者名="Sablin"

选中清除导出查看参考文献查看引证文献引用追踪共3页首页上一页第1页下一页末页 /3 跳转

	题名	作者	年代	出处	被引量
1	Disease control with sunitinib in advanced intrahepatic cholangiocarcinoma resistant to gemcitabine-oxaliplatin chemotherapy显示文摘Advanced cholangiocarcinoma is associated with poor prognostic survival and has limited therapeutic options available at present. The importance of angiogenesis and expression of pro-angiogenic factors in intrahepatic forms of cholangiocarcinoma suggest that therapies targeting angiogenesis might be useful for the treatment of this disease. Here we report three cases of patients with advanced intrahepatic cholangiocarcinoma progressive after standard chemotherapy and treated with sunitinib 50 mg/d in 6-wk cycles of 4 wk on treatment followed by 2 wk off treatment(Schedule 4/2). In all three patients, sunitinib treatment was associated with a sustained disease control superior to 4 mo, patients achieving either a partial response or stable disease. A reduction in tumor size and density was observed in all cases, suggesting tumor necrosis as a result of sunitinib treatment in these patients. In addition, sunitinib was generally well tolerated and the occurrence of side effects was managed with standard medical interventions, as required. Our results suggest that sunitinib therapy maybe associated with favorable outcomes and tolerability in patients with advanced cholangiocarcinoma. Those observations contributed to launch a prospective phase Ⅱ multicenter trial investigating sunitinib in advanced intrahepatic cholangiocarcinoma(SUN-CK study; NCT01718327).	Chantal Dreyer Marie-Paule Sablin Mohamed Bouattour Cindy Neuzillet Maxime Ronot Safi Dokmak Jacques Belghiti Nathalie Guedj Valérie Paradis Eric Raymond Sandrine Faivre	2015	World Journal of Hepatology2015，7，6：	4
2	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF - 1 and LRH - 1 显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，3：	1
3	Sequential sorafenib and sunitinib for renal cell carcinoma显示文摘	Sablin M P Negrier S Ravaud A	2009	J Urol2009，182，1：	1
4	Switch-based mechanism of kinesin motors显示文摘	Kikkawa M Sablin EP Okada Y	2001	Nature2001，411，6836：	1
5	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 显示文摘	Krylova IN Sablin EP Moore J	2005	Ce112005，120，：	1
6	Complete Mitochondrial Genomes of Ancient Canids Suggest a European Origin of Domestic Dogs显示文摘	O. Thalmann B. Shapiro P. Cui V. J. Schuenemann S. K. Sawyer D. L. Greenfield M. B. Germonpré M. V. Sablin F. López-Giráldez X. Domingo-Roura H. Napierala H-P. Uerpmann D. M. Loponte A. A. Acosta L. Giemsch R. W. Schmitz B. Worthington J. E. Buikstra A. D	2013	Science2013，，6160：	1
7	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，3：	1
8	Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1显示文摘	Sablin EP Krylova IN Fletterick RJ	2003	Mol Cell2003，11，6：	1
9	Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1显示文摘	Sablin E P Krylova I N Fletterick R J	2003	Mol Cell2003，11，6：	1
10	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 or- phan receptors SF-1 and LRH-I显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，34：	1
11	Wide-SpanSystems of Mine Detection显示文摘	Ivashov S I Sablin V N Vasilyev I A	1999	IEEE Aerospace andElectronic Systems Magazine1999，14，5：	1
12	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，3：	1
13	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，3：	1
14	Regional localization of the human platelet-derived endothelial cell growth factor (ECGF1) gene to chromosome22q13显示文摘	Stenman G Sablin P Dumanski JP	1992	Cytogenet Cell Genet1992，59，：	1
15	Sequential sorafenib and sunitinib for renal cell carcinoma 显示文摘	Sablin MP Negrier S Ravaud A	2009	J Urol2009，182，1：	1
16	Comparison of three different technologies for pupil diameter measurement 显示文摘	Sabline S Frank K Sebastian H	2003	Graefes Arch Clin Exp Ophthalmol2003，241，6：	1
17	Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF- 1 and LRH-1显示文摘	Krylova IN Sablin EP Moore J	2005	Cell2005，120，34：	1
18	Sequential sorafenib and sunitinib for renal cell carcinoma显示文摘	Sablin MP Negrier S Ravaud A	2009	J Urol2009，182，1：	1
19	Wide Span Systems of Mine Detection显示文摘	IVASHOV S I SABLIN V N VASILYEV I A	1999	IEEE Aerospace Electronic Systems Magazine1999，14，5：	1
20	Switched-based mechanism of kinesin motors显示文摘	Kikkawa M Sablin EP	2001	Nature2001，411，：	1

返回顶部每页显示：

共3页首页上一页第1页下一页末页 /3 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示