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| 1 | Increased plasma malondialdehyde and fructosamine in anemic H pylori infected patients:Effect of treatment显示文摘AIM: To unravel the possible association of malon-dialdehyde (MDA) and fructosamine in anemic H pylori infected patients and to observe the alteration in MDA and fructosamine levels in these patients after treatment for one month.METHODS: Fructosamine, MDA and glucose were estimated in 22 anemic H pylori infected patients and 16 healthy controls. Hematological parameters were also evaluated in both the groups using Sysmex-K-100 automated cell counter. The H pylori infected patients were randomly divided into two groups. H pylori infected patients in GroupⅠreceived both iron supplementation and anti-H pylori therapy, while patients in Group Ⅱ received only iron supplementation. All the biochemical and hematological parameters were estimated after one month of treatment. RESULTS: In anemic H pylori infected patients, while MDA (5.41 ± 2.16 vs 2.26 ± 0.50; P < 0.05) and fructosamine (2.64 ± 0.93 vs 1.60 ± 0.35; P < 0.05) were significantly increased, iron (32.72 ± 14.93 vs 110.25 ± 26.58; P < 0.05), hemoglobin (6.9 ± 2.6 vs 12.66 ± 0.74; P < 0.05) and ferritin (28.82 ± 16.27 vs 140.43 ± 30.72; P < 0.05) levels were significantly decreased compared with the controls. With partial correlation analysis, fructosamine was found to have a significant positive correlation with MDA. In GroupⅠ, while MDA level decreased significantly (3.11 ± 1.73 vs 5.50 ± 2.46; P < 0.05), there was a significant increase in iron (84.09 ± 29.51 vs 36.09 ± 17.81; P < 0.05), hemoglobin (10.40 ± 1.11 vs 7.42 ± 1.90; P < 0.05) and ferritin (116.91 ± 63.34 vs 30.46 ± 17.81; P < 0.05) levels after one month. There was no significant change in the levels of fructosamine in groupⅠafter treatment. Similarly, no significant alterations were noted in the levels of MDA, fructosamine, hemoglobin or ferritin in Group Ⅱ patients after one month of treatment.CONCLUSION: An increased level of fructosamine and MDA was found in anemic H pylori infected patients. Present data supports the premise that lipid peroxides per se do play a role in the glycation of plasma proteins. Furthermore, the findings from this study indicate that treatment for both anemia and H pylori infections is required for lowering the levels of lipid peroxides in these patients. | G Vijayan RC Sundaram Zachariah Bobby Abdoul Hamide N Selvaraj N Rattina Dasse | 2007 | World Journal of Gastroenterology2007，13，5： | 4 |
| 2 | ICGA-PSOELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented显示文摘 | Saraswathi S Sundaram s Sundararjan N | 2011 | IEEE/ACM Transactions on Computational Biology and Bioinformatics2011，8，2： | 1 |
| 3 | Biomarkers for early detection of sickle nephropathy显示文摘 | Sundaram N Bennett M Wilhelm J | | 0，，07： | 1 |
| 4 | Development of multifunctional chitosan beads for fluoride removal显示文摘 | Viswanathan N Sundaram C S Meenakshi S | | 0，，1： | 1 |
| 5 | Tibialplateau fraeture following gracilis-semitendinosus anterior eruciate ligament reeonstruction : the tibial tunnel stress-riser显示文摘 | Sundaram RO Cohen D Barton-Hanson N | 2006 | The Knee2006，13，： | 1 |
| 6 | Biomaterials for Blood-Contacting Applications显示文摘 | J M Courtney N M K Lamba M Sundaram C D Forbes | 1994 | Biomaterials1994，10，： | 1 |
| 7 | Role of proinflammatory cytokines and chemokines in chronic arthropalhy in CHIKV infection 显示文摘 | Chaaitanya IK Mumganandam N Sundaram SG | 2011 | Viral Immunol2011，24，4： | 1 |
| 8 | Kinetics and mechanism of removal of methylene blue by adsorption on various carbons-a comparative study 显示文摘 | Kannan N Sundaram M M | 2001 | Dyes Pigments2001，51，1： | 1 |
| 9 | Tibial plateau fracture following gracilis-semitendinosus anterior crueiate ligament reeonstruetion: the tibial tunnel stress-riser 显示文摘 | Sundaram RO Cohen D Barton-Hanson N | 2006 | The Knee2006，13，： | 1 |
| 10 | Computational Predictions of Heat Transfer and Film- Cooling for a Turbine Blade with NonAxisymmetric Endwall Contouring显示文摘 | LYNCH S P THOLE A K SUNDARAM N | 2011 | ASME Journal of Turbomahinery2011，133，04： | 1 |
| 11 | Study on dyeing of silk using reactive dyes显示文摘 | Lakkumi N sundaram A | 1991 | Textile Dyer & Printer1991，24，4： | 1 |
| 12 | Comparison of helical computerized tomography and plain radiography for estimating urinary stone size显示文摘 | Narepalem N Sundaram C Boridy I | 2002 | J Urol2002，167，： | 1 |
| 13 | Validation of molecular markers linked to fertility restorer gene (s) forWA-CMS lines of rice 显示文摘 | Sheeba N K Viraktamath B C Sivaramakrishnan S Gangashetti M G Khera P Sundaram R M | 2009 | Euphytica2009，167，： | 1 |
| 14 | Crystallization of hydroxyapatite at physiological temperature 显示文摘 | ASHOK M SUNDARAM N M KALKURA S N | 2003 | Mater Lett2003，57，13： | 1 |
| 15 | Sorption behaviour of fluoride on carboxylated cross-linked chitosan beads 显示文摘 | Viswanathan N Sundaram C S Meenakshi S | 2009 | Colloids Surf B2009，68，1： | 1 |
| 16 | Experience with an inver- ter-based dynamic voltage restorer显示文摘 | Woodley N H Morgan L Sundaram A | 1999 | IEEE Transactions on Power Delivery1999，14，3： | 1 |
| 17 | Experience with an inverter-based dynamic voltage restorer显示文摘 | WOODLEY N H MORGAN L SUNDARAM A | 1999 | IEEE Transactions on Power Delivery1999，14，3： | 1 |
| 18 | Development of multifunctional ehitosan beads for fluoride removal显示文摘 | Viswanathan N Sundaram C S Meenakshi S | 2009 | Hazard Mater2009，167，13： | 1 |
| 19 | Immunogenicity of novel consensus-based DNA vaccines against chikungunya virus 显示文摘 | Muthumani K Lankaraman KM Laddy DJ Sundaram SG Chung CW Sako E Wu L Khan A Sardesai N Kim JJ Vijayachari P Weiner DB | 2008 | Vaccine2008，26，40： | 1 |
| 20 | A DNA vaccine against chikungunya virus is protcctivc in mice and induces neutralizing antibodies in mice and nonhuman primatcs 显示文摘 | Mallilankaraman K Shedlock DJ Bao H Kawalekar OU Fagone P Ramanathan AA Ferraro B Stabcnow J Vijayachari P Sundaram SG Muruganandam N Sarangan G Srikanth P Khan AS Lewis MG Kim JJ Sardcsai NY Muthumani K Weiner DB | 2011 | PLoS Negl Trop Dis2011，5，1： | 1 |
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