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110篇 您的检索式：作者名="J M Courtney"

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	题名	作者	年代	出处	被引量
1	Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.	Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele	2009	World Journal of Gastroenterology2009，15，10：	20
2	Migrastatin and a new compound isoMigrastatin from Streptomyces platensis显示文摘	Woo E J Starks Courtney M	2002	J Antibiotics2002，55，2：	1
3	Central venous catheters:a survey of ICU practices显示文摘	Rickard CM Courtney M Webster J	2004	J Adv Nurs2004，48，3：	1
4	Biomaterials for Blood-Contacting Applications显示文摘	J M Courtney N M K Lamba M Sundaram C D Forbes	1994	Biomaterials1994，10，：	1
5	Trichodermamides A and B, cytotoxic modifided dipeptides from themarine-derived fungus Trichoderrna virens显示文摘	GARO E COURTNEY M S PAUL R J	2003	J Nat Prod2003，66，：	1
6	Blood purification by hemoperfusion 显示文摘	Klinkman H Falkenhagen D Courtney J M	1979	Int J Artif Organs1979，2，：	1
7	A prospective com-parison of magnetic resonance cholangiopancreatography with en-doscopes retrograde cholangiopancreatography in the evaluation ofpatients with suspected hiliary tract disease显示文摘	Varghese J Farrell M A Courtney G	1999	Clin Radiol1999，54，8：	1
8	Reaction Rates During Mechanical Alloying 显示文摘	AIKIN B J M COURTNEY T H etal	1991	Materials Science and Engineering1991，，147：	1
9	High - frequency oscillatory ventilation versus conventional mechanicalventilation for very - low - birth - weight infants 显示文摘	COURTNEY S E DURAND D J ASSELIN J M	2002	N Engl J Med2002，347，9：	1
10	The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function显示文摘	Brodbeck J Davies A Courtney J M		0，，10：	1
11	Screening of in vitro cytotoxicity by the adhensive film test显示文摘	SRIVASTAVA S GORHAM S D COURTNEY J M	1990	B iomaterials1990，11，3：	1
12	The kinetics of composite particle formation during mechanical alloying 显示文摘	AIKIN B J M COURTNEY T H	1993	Metallurgical Transactions A1993，24，3：	1
13	Recurrent dense deposit disease after renal transplantation:an emerging role for complementary therapies显示文摘	McCaughan J A 0 Rourke D M Courtney A E	2012	Am J Transplant2012，12，4：	1
14	Highfrequency oscillatory ventilation versus conven tional mechanicalventilation for very-low-birth weight infants 显示文摘	COURTNEY S E DURAND D J ASSELIN J M	2002	The newengland journal of medicine2002，347，9：	1
15	Inhibitors of hepatitis C virus NS3·4A protease. Part 3: P 2 proline variants显示文摘	Robert B Perni Luc J Farmer Kevin M Cottrell John J Court Lawrence F Courtney David D Deininger Cynthia A Gates Scott L Harbeson Joseph L Kim Chao Lin Kai Lin Yu-Ping Luong John P Maxwell Mark A Murcko Janos Pitlik B.Govinda Rao Wayne C Schairer Roger D T	2004	Bioorganic & Medicinal Chemistry Letters2004，，8：	1
16	Routine changing of intravenousadministration sets does not reduce colonization or infection in centralvenous catheters显示文摘	Rickard CM Lipman J Courtney M		0，，08：	1
17	Individuals - area relationships : the relationship between animal population density and area显示文摘	Connor E F Courtney A C Yoder J M	2000	Ecology2000，81，：	1
18	The kinetic of composite particle formation during mechanical alloying 显示文摘	Aikin B J M Courtney T H	1993	Metall Trans1993，24，3：	1
19	An area Specialized for Spatial Working memory in human frontal Cortex显示文摘	Courtney S M Petit L Maisog J M	1998	Science1998，279，5355：	1
20	Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3显示文摘	Hongisto V Smeds N Brecht S Herdegen T Courtney M J Coffey E T		0，，17：	1

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