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| 1 | 用ISSR标记技术分析中国和瑞典甘蓝型油菜的遗传多样性显示文摘利用ISSR(inter simplesequencerepeats)技术比较了 2 4份中国半冬性、瑞典冬性和瑞典春性油菜的遗传多样性。 2 0个引物扩增出了 12 5条多态性带。UPGMA聚类分析将 2 4份材料分为 3组。第一组为 6份瑞典冬性和 8份中国半冬性材料 ,第二组为 2个中国半冬性材料湘油 15号和保 81,第三组为 8份瑞典春性材料。主成分分析结果与聚类分析结果相似 ,表明研究所用中国半冬性、瑞典冬性和瑞典春性 3类材料彼此间区分明显 ,中国半冬性油菜与瑞典冬性油菜的遗传关系比与瑞典春性油菜的关系近。结果显示 。 | 马朝芝 傅廷栋 Stine Tuevesson Bo Gertsson | 2003 | 中国农业科学2003，36，11： | 74 |
| 2 | Portal vein thrombosis, mortality and hepatic decompensation in patients with cirrhosis: A meta-analysis显示文摘AIM: To determine the clinical impact of portal vein thrombosis in terms of both mortality and hepatic decompensations(variceal hemorrhage, ascites, portosystemic encephalopathy) in adult patients with cirrhosis.METHODS: We identified original articles reported through February 2015 in MEDLINE, Scopus, Science Citation Index, AMED, the Cochrane Library, and relevant examples available in the grey literature. Two independent reviewers screened all citations for inclusion criteria and extracted summary data. Random effects odds ratios were calculated to obtain aggregate estimates of effect size across included studies, with 95%CI.RESULTS: A total of 226 citations were identified and reviewed, and 3 studies with 2436 participants were included in the meta-analysis of summary effect. Patients with portal vein thrombosis had an increased risk of mortality(OR = 1.62, 95%CI: 1.11-2.36, P = 0.01). Portal vein thrombosis was associated with an increased risk of ascites(OR = 2.52, 95%CI: 1.63-3.89, P < 0.001). There was insufficient data available to determine the pooled effect on other markers of decompensation including gastroesophageal variceal bleeding or hepatic encephalopathy. CONCLUSION: Portal vein thrombosis appears to increase mortality and ascites, however, the relatively small number of included studies limits more generalizable conclusions. More trials with a direct comparison group are needed. | Jonathan G Stine Puja M Shah Scott L Cornella Sean R Rudnick Marwan S Ghabril George J Stukenborg Patrick G Northup | 2015 | World Journal of Hepatology2015，7，27： | 42 |
| 3 | Malignant peritoneal mesothelioma显示文摘Malignant mesothelioma is a highly aggressive neoplasm.The incidence of malignant mesothelioma is increasing worldwide.Diffuse malignant peritoneal mesothelioma(DMPM) represents one-fourth of all mesotheliomas.Association of asbestos exposure with DMPM has been observed,especially in males.The great majority of patients present with abdominal pain and distension,caused by accumulation of tumors and ascitic ? uid.In the past,DMPM was considered a pre-terminal condition;therefore attracted little attention.Patients invariably died from their disease within a year.Recently,several prospective trials have demonstrated a median survival of 40 to 90 mo and 5-year survival of 30% to 60% after combined treatment using cytoreductive surgery and perioperative intraperitoneal chemotherapy.This remarkable improvement in survival has prompted new search into the medical science related to DMPM,a disease previously ignored as uninteresting.This review article focuses on the key advances in the epidemiology,diagnosis,staging,treatments and prognosis of DMPM that have occurred in the past decade. | Stine Munkholm-Larsen Christopher Q Cao Tristan D Yan | 2009 | World Journal of Gastrointestinal Surgery2009，1，1： | 19 |
| 4 | A pharmacological review on intraperitoneal chemotherapy for peritoneal malignancy显示文摘Perioperative intraperitoneal chemotherapy in combination with cytoreductive surgery has been shown to be of benefit for treating selected patients with peritoneal surface malignancy.It has become a new standard of care in the management of diffuse malignant peritoneal mesothelioma and peritoneal dissemination of appendiceal malignancy.Numerous recent publications on carcinomatosis from colorectal cancer and gastric cancer identify groups of patients that would benef it from this local-regional approach for prevention and treatment of carcinomatosis.This review focuses on pharmacological information regarding intraperitoneal chemotherapeutic agents commonly used in gastrointestinal oncology. | Tristan D Yan Christopher Qian Cao Stine Munkholm-Larsen | 2010 | World Journal of Gastrointestinal Oncology2010，2，2： | 14 |
| 5 | Probiotic bacteria change Escherichia coli-induced gene expression in cultured colonocytes:Implications in intestinal pathophysiology显示文摘AIM: To investigate the change in eukaryotic gene expression profile in Caco-2 cells after infection with strains of Escherichia coli and commensal probiotic bacteria. METHODS: A 19 200 gene/expressed sequence tag gene chip was used to examine expression of genes after infection of Caco-2 cells with strains of normal flora E. coli,Lactobacillus plantarum,and a combination of the two. RESULTS: The cDNA microarray revealed up-regulation of 155 and down-regulation of 177 genes by E. coli . L. plantarum up-regulated 45 and down-regulated 36 genes. During mixed infection,27 genes were up-regulated and 59 were down-regulated,with nullification of stimulatory/inhibitory effects on most of the genes. Expression of several new genes was noted in this group. CONCLUSION: The commensal bacterial strains used in this study induced the expression of a large number of genes in colonocyte-like cultured cells and changed the expression of several genes involved in important cellular processes such as regulation of transcription,protein biosynthesis,metabolism,cell adhesion,ubiquitination,and apoptosis. Such changes induced by the presence of probiotic bacteria may shape the physiologic and pathologic responses they trigger in the host. | Pinaki Panigrahi Gheorghe T Braileanu Hegang Chen O Colin Stine | 2007 | World Journal of Gastroenterology2007，13，47： | 10 |
| 6 | Is regular physical activity a key to mental health? Commentary on 'Association between physical exercise and mental health in 1.2 million individuals in the USA between 2011 and 2015:A cross-sectional study',by Chekroud et al.,published in Lancet Psychiat显示文摘The recent publication by Chekroud et al . in Lancet Psychiatry focuses on the relationship between physical exercise and mental health.Mental health is defined as optimal personal functioning 'resulting in productive activities,fulfilling relationships with other people,and the ability to adapt to change and to cope with adversity'.(p.4) Recently,mental health has no longer been described as a dichotomous state but as a continuum,with personal mental states ranging from highly functional to mentally ill. | Anne-Marie Elbe Stine NylANDsted Lyhne Esben Elholm Madsen Peter Krustrup | 2019 | Journal of Sport and Health Science2019，8，1： | 6 |
| 7 | Treatment of Budd-Chiari syndrome with a focus on transjugular intrahepatic portosystemic shunt显示文摘AIM:To evaluate long-term complications and survival in patients with Budd-Chiari syndrome (BCS) referred to a Danish transjugular intrahepatic portosystemic shunt (TIPS) centre.METHODS:Twenty-one consecutive patients from 1997-2008 were retrospectively included [15 women and 6 men,median age 40 years (range 17-66 years)].Eighteen Danish patients came from the 1.8 million catchment population of Aarhus University Hospital and three patients were referred from Scandinavian hospitals.Management consisted of tests for underlying haematological,endocrinological,or hypercoagulative disorders parallel to initiation of specific treatment of BCS.RESULTS:BCS was mainly caused by thrombophilic (33%) or myeloproliferative (19%) disorders.Fortythree percents had symptoms for less than one week with ascites as the most prevalent finding.Fourteen (67%) were treated with TIPS and 7 (33%) were manageable with treatment of the underlying condition and diuretics.The median follow-up time for the TIPS-treated patients was 50 mo (range 15-117 mo),and none required subsequent liver transplantation.Ascites control was achieved in all TIPS patients with a marked reduction in the dose of diuretics.A total of 14 TIPS revisions were needed,mostly of uncovered stents.Two died during follow-up:One non-TIPS patient worsened after 6 mo and died in relation to transplantation,and one TIPS patient died 4 years after the TIPS-procedure,unrelated to BCS.CONCLUSION:In our BCS cohort TIPS-treated patients have near-complete survival,reduced need for diuretics and compared to historical data a reduced need for liver transplantation. | Anders Bay Neumann Stine Degn Andersen Dennis Tφnner Nielsen Peter Holland-Fischer Hendrik Vilstrup Henning Grφnbk | 2013 | World Journal of Hepatology2013，5，1： | 5 |
| 8 | Diagnosis and management of iatrogenic endoscopic perforations: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement显示文摘 | Gregorios Paspatis Jean-Marc Dumonceau Marc Barthet S?ren Meisner Alessandro Repici Brian Saunders Antonios Vezakis Jean Gonzalez Stine Turino Zacharias Tsiamoulos Paul Fockens Cesare Hassan | 2014 | Endoscopy2014，，： | 4 |
| 9 | Advanced non-alcoholic steatohepatitis cirrhosis: A high-risk population for pre-liver transplant portal vein thrombosis显示文摘AIM To examine if liver transplant recipients with high-risk non-alcoholic steatohepatitis(NASH) are at increased risk for pre-transplant portal venous thrombosis.METHODS Data on all liver transplants in the United States from February 2002 through September 2014 were analyzed. Recipients were sorted into three distinct groups: High-risk(age > 60, body mass index > 30 kg/m2, hypertension and diabetes), low-risk and non-NASH cirrhosis. Multivariable logistic regression models were constructed.RESULTS Thirty-five thousand and seventy-two candidates underwent liver transplantation and of those organ recipients, 465 were transplanted for high-risk and 2775 for lowrisk NASH. Two thousand six hundred and twentysix(7.5%) recipients had pre-transplant portal vein thrombosis; 66(14.2%) of the high-risk NASH group had portal vein thrombosis vs 328(11.8%) of the lowrisk NASH group. In general, all NASH recipients were less likely to be male or African American and more likely to be obese. In adjusted multivariable regression analyses, high-risk recipients had the greatest risk ofpre-transplant portal vein thrombosis with OR = 2.11(95%CI: 1.60-2.76, P < 0.001) when referenced to the non-NASH group.CONCLUSION Liver transplant candidates with high-risk NASH are at the greatest risk for portal vein thrombosis development prior to transplantation. These candidates may benefit from interventions to decrease their likelihood of clot formation and resultant downstream hepatic decompensating events. Prospective study is needed. | Jonathan G Stine Curtis K Argo Shawn J Pelletier Daniel G Maluf Stephen H Caldwell Patrick G Northup | 2017 | World Journal of Hepatology2017，9，3： | 2 |
| 10 | Portrait of the PI3K/AKT-pathway in colorectal cancer显示文摘 | Stine Aske Danielsen Peter Wold Eide Arild Nesbakken Tormod Guren Edward Leithe Ragnhild A. Lothe | 2014 | BBA - Reviews on Cancer2014，，： | 2 |
| 11 | Review article: prescribing medications in patients with cirrhosis – a practical guide显示文摘 | J. H. Lewis J. G. Stine | 2013 | Aliment Pharmacol Ther2013，，： | 2 |
| 12 | No difference in portal and hepatic venous bacterial DNA in patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt insertion显示文摘 | Christian Mortensen Stine Karlsen Henning Gr?nb?k Dennis T. Nielsen Susanne Frevert Jens O. Clemmesen S?ren M?ller J?rgen S. Jensen Flemming Bendtsen | 2013 | Liver Int2013，，9： | 2 |
| 13 | 全电视辅助胸腔镜手术治疗早期非小细胞肺癌显示文摘从出现至今,微创手术对所有的外科分支学科均产生了巨大影响。电视辅助胸腔镜(VATS)肺叶切除术治疗早期非小细胞肺癌于20世纪90年代早期被首次报道,自此在许多医疗中心中逐渐普及。这项较新的技术的支持者列举了该技术在围手术期可能获得的许多有利结果,可能主要是因为该技术可减少手术创伤和应激反应。然而,由于仍缺乏有关长期生存和复发率的详实的临床数据,大部分胸心外科医生仍然持怀疑态度。'全'VATS的定义目前仍不明确,之前的许多研究将其视为'小切口开胸肺叶切除术',而非VATS肺叶切除术。在此,我们复习了有关全VATS肺叶切除术的文献,特别关注了直接对比VATS肺叶切除术和传统开胸肺叶切除术的比较研究。 | Christopher Q. CAO Stine MUNKHOLM-LARSEN Tristan D. YAN 王炜(翻译) 邵文龙(翻译) 何建行(校对) | 2010 | 中国肺癌杂志2010，13，3： | 2 |
| 14 | Multilocus sequence typing has better discriminatory ability for typing Vibrio cholerae than does pulsed field gel electrophoresis and provide a measure of phylogenetic relatedness显示文摘 | Kotetishvili M Stine OC Chen Y | 2003 | J Clin Microbiol2003，41，5： | 1 |
| 15 | High levels of microRNA - 21 in the stroma of colorectal cancers predict short disease- free survival in stage II colon cancer patients显示文摘 | Boye Schnack Nielsen Stine J? rgensen Jacob Ulrik Fog | 2011 | Springer2011，28，： | 1 |
| 16 | Global survey of diversity among environmental saltwater Bacteriovoracaceae 显示文摘 | Pineiro S A Stine O C Chauhan A | 2007 | Environmental Microbiology2007，9，10： | 1 |
| 17 | Selivity in pseudophase liquid chromatography 显示文摘 | ARMSTRONG D W STINE G Y | 1983 | Anal Chem1983，55，14： | 1 |
| 18 | Is Local Government Revenue Response to Federal Aid Symmetrical显示文摘 | Stine William F | | 0，，47： | 1 |
| 19 | Direct and indirect effects: Classical and bootstrap estimates of variability 显示文摘 | BOI LEN K A STINE R | 1990 | Sociological Methodology1990，20，1： | 1 |
| 20 | Physiology of cell volume regulation in vertebrates 显示文摘 | Else Kay Hoffmann Ian Henry Lambert Stine F Pedersen | 2009 | Physiol Rev2009，89，1： | 1 |
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