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    题名 作者 年代 出处 被引量
1The precipitation strengthening behavior of Cu-rich phase in Nb contained advanced Fe-Cr-Ni type austenitic heat resistant steel for USC power plant applicationCheng-yu Chi a, Hong-yao Yu b, Jian-xin Dong b, Wen-qing Liu c, Shi-chang Cheng d, Zheng-dong Liu d, Xi-shan Xie b a School of Metallurgical and Ecological Engineering, University of Science & Technology Beijing, Beijing 100083, China b School of Materials Science and Engineering, University of Science & Technology Beijing, Beijing 100083, China c Instrumental Analysis & Research Center, Shanghai University, Shanghai 200444, China d Central Iron and Steel Research Institute, Beijing 100081, China 2012Progress in Natural Science:Materials International2012,22,3:20
2Endoscopy and polyps-diagnostic and therapeutic advances in management显示文摘Despite multiple efforts aimed at early detection through screening, colon cancer remains the third leading cause of cancer-related deaths in the United States, with an estimated 51000 deaths during 2013 alone. The goal remains to identify and remove benign neoplastic polyps prior to becoming invasive cancers. Polypoid lesions of the colon vary widely from hyperplastic, hamartomatous and inflammatory to neoplastic adenomatous growths. Although these lesions are all benign, they are common, with up to one-quarter of patients over 60 years old will develop pre-malignant adenomatous polyps. Colonoscopy is the most effective screening tool to detect polyps and colon cancer, although several studies have demonstrated missed polyp rates from 6%-29%, largely due to variations in polyp size. This number can be as high as 40%, even with advanced (> 1 cm) adenomas. Other factors including sub-optimal bowel preparation, experience of the endoscopist, and patient anatomical variations all affect the detection rate. Additional challenges in decision-making exist when dealing with more advanced, and typically larger, polyps that have traditionally required formal resection. In this brief review, we will explore the recent advances in polyp detection and therapeutic options.Scott R Steele Eric K Johnson Bradley Champagne Brad Davis Sang Lee David Rivadeneira Howard Ross Dana A Hayden Justin A Maykel 2013World Journal of Gastroenterology2013,19,27:16
3Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity显示文摘AIM To establish a model to enrich and characterize stemlike cells from murine normal liver and hepatocellular carcinoma(HCC) cell lines and to further investigate stem-like cell association with epithelial-to-mesenchymal transition(EMT).METHODS In this study,we utilized a stem cell conditioned serumfree medium to enrich stem-like cells from mouse HCC and normal liver cell lines,Hepa 1-6 and AML12,respectively.We isolated the 3-dimensional spheres and assessed their stemness characteristics by evaluating theRNA levels of stemness genes and a cell surface stem cell marker by quantitative reverse transcriptase-PCR(q RTPCR).Next,we examined the relationship between stem cells and EMT using q RT-PCR.RESULTS Three-dimensional spheres were enriched by culturing murine HCC and normal hepatocyte cell lines in stem cell conditioned serum-free medium supplemented with epidermal growth factor,basic fibroblast growth factor and heparin sulfate.The 3-dimensional spheres had enhanced stemness markers such as Klf4 and Bmi1 and hepatic cancer stem cell(CSC) marker Cd44 compared to parental cells grown as adherent cultures.We report that epithelial markers E-cadherin and ZO-1 were downregulated,while mesenchymal markers Vimentin and Fibronectin were upregulated in 3-dimensional spheres.The 3-dimensional spheres also exhibited changes in expression of Snai,Zeb and Twist family of EMT transcription factors.CONCLUSION Our novel method successfully enriched stem-like cells which possessed an EMT phenotype.The isolation and characterization of murine hepatic CSCs could establish a precise target for the development of more effective therapies for HCC.Aparna Jayachandran Ritu Shrestha Bijay Dhungel I-Tao Huang Marianna Yumi Kawashima Vasconcelos Brian J Morrison Charmaine A Ramlogan-Steel Jason C Steel 2017World Journal of Stem Cells2017,9,9:4
42008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis显示文摘Jacqueline E Tate Anthony H Burton Cynthia Boschi-Pinto A Duncan Steele Jazmin Duque Umesh D Parashar 2012The Lancet Infectious Diseases2012,,2:2
5Nonlinear Dynamics of a Passively Mode-Locked Fiber Laser Containing a LongPeriod Fiber Grating 显示文摘Karar A S Smy T Steele A L 2008Quantum Electronics IEEE Journal of2008,44,3:1
6Atomic force microscopy study of microbiological influenced corrosion SRB biofilms on steel surface显示文摘Steele A Goddard D T Beech I B 1994International Biodeterioration and Biodegradation1994,34,:1
7Examining the consequences of exposure to racism for the executive functioning of Black students 显示文摘BAIRN A STEELE R J 2010J Experimental Soc Psychol2010,46,:1
8Mosaiccomplementation demonstrates a regulatory role for myo-sin VIIa in actin dynamics of stereocilia显示文摘Prosser H M Rzadzinska A K Steel K P 2008Mol CellBiol2008,28,5:1
9Wheat classification using image analysis and crush-force parameters显示文摘Zayas I Y Steele J L Katcevich A 1996Transaotiona of the ASAE1996,39,6:1
10Towards the remote sensing of matorral vegetation physiology:relationships between spectral reflectance,pigment,and biophysical characteristics of semiarid bushland canopies显示文摘Blackburn G A Steele C M 0,,3:1
11Pyrophoric nature of iron sulfides 显示文摘WALKER R STEEL A D 1996Industrial & Engineering Chemistry Research1996,35,5:1
12Mg2+dependence of halothane-induced Ca2+release from the sarcoplasmic reticulum in rat skeletal muscle显示文摘Duke A M Hopkins P M Steele D S 2003J Physiology2003,551,2:1
13Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory maerophage populations显示文摘Hartnell A Steel J Turley H 2001Blood2001,97,1:1
14Measurement of retinal vessel widths from fundus images based on 2D modeling 显示文摘LOWELL J A HUNTER A STEEL D 2004IEEE Transactions on Medical Imaging2004,23,10:1
15Trophoblasts expression Fas ligand: A proposed mechanism for immune privilege in placenta and maternal invasion显示文摘Uckan D Steele A Cherry 1997Mol Hum Reprod1997,3,8:1
16Failure of early diag- nosis in symptomatic Duchenne muscular dystrophy显示文摘Bushby K M Hill A Steele J G 1999Lancet1999,353,9152:1
17Energy homeostasis and cancer prevention: the AMP-activated protein kinase显示文摘FAY J R STEELE V CROWEEL J A 2009Cancer Prev Res2009,2,4:1
18An active contour model for segmenting and measuring retinal vessels显示文摘AL-DIRI B HUNTER A STEEL D 2009IEEE Transactions on Medical Imaging2009,28,9:1
19Transcriptomic analysis reveals calcium regulation of specific promoter motifs in Arabidopsis 显示文摘Whalley H J Sargeant A W Steele J F 2011Plant Cell2011,23,11:1
20Frequency control of crane hoist speed显示文摘Steel A 2003Times International2003,27,5:1
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