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11篇 您的检索式:作者名="ST Jeng"
    题名 作者 年代 出处 被引量
1Acute disseminated encephalomyelitis :a follow-up study in Taiwan显示文摘Lin CH Jeng JS Hsien ST 2007J Neurol Neurosurg Psychiatry2007,78,2:1
2Connective tissue growth factor and its role in lung adenocarcinoma invasion and metastasis显示文摘Chang CC Shih JY Jeng YM Su JL Lin BZ Chen ST 2004J Natl Cancer Inst2004,96,5:1
3Insulin-like growth factor II mRNA- binding protein 3 expression promotes tumor formation and invasion and predicts poor prognosis in oral squamous cell carcinoma 显示文摘Lin CY Che ST Jeng YM 2011J Oral Pathol Med2011,40,9:1
4Insulin-like growth factor II mRNA-binding protein 3 expression predicts unfavorable prognosis in patients with neuroblastoma 显示文摘Chen ST Jeng YM Chang CC 2011Cancer Sci2011,102,12:1
5Acute disseminated encephalomyelitis: a follow-up study in Taiwan显示文摘Lin CH Jeng JS Hsieh ST 2007Neurol Neurosurg Psychiatry2007,78,2:1
6Acute disseminated encephalomyelitis:a follow up study in Taiwan显示文摘 Jeng JS Hsien ST 2007J Neurol Neurosurg Psychiatry2007,78,16:1
7Oral immunization of mice using transgenic tomato fruit expressing VPI protein from enterovirus 71 显示文摘Chen HF Chang MH Chiang BL Jeng ST 2006Vaccine2006,24,15:1
8Homocysteine impairs the nitric oxide synthase pathway显示文摘Stühlinger MC Tsao PS Jeng HH 0,,21:1
9MicroRNA-519c suppresses hypoxia-inducible factor- 1α ex- pression and tumor angiogenesis 显示文摘Cha ST Chen PS Johansson G Chu CY Wang MY Jeng YM 2010Cancer Res2010,70,7:1
10Acute disseminated encephalomyelitis:a follow-up study in Taiwan显示文摘Lin CH Jeng JS Hsieh ST 2007J Neurol Neurosurg Psychiatry2007,78,2:1
11Construction of a Der p2-transgenic plant for the alleviation of airway inflammation显示文摘In clinical therapy,the amount of antigen administered to achieve oral tolerance for allergic diseases is large,and the cost is a major consideration.In this study,we used tobacco plants to develop a large-scale protein production system for allergen-specific immunotherapy,and we investigated the mechanisms of oral tolerance induced by a transgenic plant-derived antigen.We used plants(tobacco leaves)transgenic for the Dermatophagoides pteronyssinus 2(Der p2)antigen to produce Der p2.Mice received total protein extract from Der p2 orally once per day over 6 days(days 0–2 and days 6–8).Mice were also sensitized and challenged with yeast-derived recombinant Der p2(rDer p2),after which the mice were examined for airway hyper-responsiveness and airway inflammation.After sensitization and challenge with rDer p2,mice that were fed with total protein extracted from transgenic plants showed decreases in serum Der p2-specific IgE and IgG1 titers,decreased IL-5 and eotaxin levels in bronchial alveolar lavage fluid,and eosinophil infiltration in the airway.In addition,hyper-responsiveness was also decreased in mice that were fed with total protein extracted from transgenic plants,and CD4^(+)CD25^(+)Foxp3^(+) regulatory T cells were significantly increased in mediastinal and mesenteric lymph nodes.Furthermore,splenocytes isolated from transgenic plant protein-fed mice exhibited decreased proliferation and increased IL-10 secretion after stimulation with rDer p2.The data here suggest that allergen-expressing transgenic plants could be used for therapeutic purposes for allergic diseases.CC Lee H Ho KT Lee ST Jeng BL Chiang 2011Cellular & Molecular Immunology2011,8,5:0
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