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| 1 | Clonal Characterization of Bone Marrow Derived Stem Cells and Their Application for Bone Regeneration显示文摘Tissue engineering allows the design of functionally active cells within supportive bio-scaffolds to promote the development of new tissues such as cartilage and bone for the restoration of pathologically altered tissues.However,all bone tissue engineering applications are limited by a shortage of stem cells.The adult bone marrow stroma contains a subset of nonhematopoietic cells referred to as bone marrow mesenchymal stem cells(BMSCs).BMSCs are of interest because they are easily isolated from a small aspirate of bone marrow and readily generate single-cell-derived colonies.These cells have the capacity to undergo extensive replication in an undifferentiated state ex vivo.In addition,BMSCs have the potential to develop either in vitro or in vivo into distinct mesenchymal tissues,including bone,cartilage,fat,tendon,muscle,and marrow stroma.Thus,BMSCs are an attractive cell source for tissue engineering approaches.However,BMSCs are not homo-geneous and the quantity of stem cells decreases in the bone marrow in aged population.A sequential loss of lineage differentiation potential has been found in the mixed culture of bone marrow stromal cells due to a heterogenous popu-lation.Therefore,a number of studies have proposed that homogenous bone marrow stem cells can be generated from clonal culture of bone marrow cells and that BMSC clones have the greatest potential for the application of bone regeneration in vivo. | Shobha Mareddy Ross Crawford | 2010 | International Journal of Oral Science2010，2，3： | 15 |
| 2 | Intestinal barrier function and metabolic/liver diseases显示文摘Dietary,environmental or genetic changes contribute to the development of several metabolic and neurological diseases.Extensive research efforts have been directed towards examining how these fac-tors modulate gut bacterial composition.However,the mechanisms by which changes in gut bacterial diversity affect host function are not completely defined.Intestinal barrier dysfunction is being increasingly recognized as an early or initiating step in communicating bacterial diversity-dependent changes to the host.Here,we review the functional composition of the intestinal barrier and describe the consequences of the breach of this barrier.The functional layers of the intestinal barrier provide an initial defense and prevent the infiltration of bacteria or bacterial products from the gut lumen to the underlying lamina propria.Mesenteric lymph nodes subsequently act as the first firewall where dendritic cells from the lamina propria transport the infiltrated bacteria or bacterial products during the early stages of barrier dysfunction.When overwhelmed,the liver functions as the second firewall to detoxify bacterial endotoxins,such as lipopolysaccharide(LPS),and limit systemic involvement.Continuous translocation of LPS from the leaky gut to the liver results in liver damage or dysfunction that leads to the development of type 2 diabetes,atherosclerosis,heart disease,heart failure and also neurological dis-eases,such as Alzheimer’s and Parkinson’s disease.Thus,targeted restoration of intestinal barrier function represents a novel strategy for the attenuation of multiple diseases. | Siddhartha S.Ghosh Jing Wang Paul J.Yannie Shobha Ghosh | 2020 | Liver Research2020，4，2： | 4 |
| 3 | Evaluation of Traditional Indian Antidiabetic Medicinal Plants for Human Pancreatic Amylase Inhibitory Effect In Vitro显示文摘 | Sudha Ponnusamy Remya Ravindran Smita Zinjarde Shobha Bhargava Ameeta Ravi Kumar | 2010 | Evidence-Based Complementary and Alternative Medicine2010，，： | 3 |
| 4 | Fault analysis method of integrated high voltage direct current transmission lines for onshore wind farm显示文摘Voltage source converter(VSC) based high voltage direct current(HVDC) transmission is most suited for the wind farm as it allows flexibility for reactive power control in multi-terminal transmission lines and transmits low power over smaller distance. In this work, a new method has been proposed to detect the fault, identify the section of faults and classify the pole of the fault in DC transmission lines fed from onshore wind farm. In the proposed scheme, voltage signal from rectifier end terminal is extracted with sampling frequency of 1 k Hz given as the input to the detection, classification and section discrimi-nation module. In this work, severe AC faults are also considered for section discrimination. Proposed method uses fuzzy inference system(FIS) to carry out all relaying task. The reach setting of the relay is 99.9% of the transmission line. Besides, the protection covers and discriminates the grounding fault with fault resistance up to 300 Ω.Considering the results of the proposed method, it can beused effectively in real power network. | Shobha AGARWAL Aleena SWETAPADMA Chinmoy PANIGRAHI Abhijit DASGUPTA | 2019 | Journal of Modern Power Systems and Clean Energy2019，7，3： | 2 |
| 5 | Infection potpourri: Are we watching?显示文摘 | Rama Chaudhry Anubhav Pandey Anupam Das Shobha Broor | 2009 | Indian Journal of Pathology and Microbiology2009，，1： | 2 |
| 6 | A Prospective Cohort Study of Emergence Agitation in the Pediatric Postanesthesia Care Unit显示文摘 | Terri Voepel-Lewis Shobha Malviya Alan R. Tait | 2003 | Anesthesia & Analgesia2003，，6： | 2 |
| 7 | Rationally engineered 3D-dendritic cell-like morphologies of LDH nanostructures using graphene-based core-shell structures显示文摘Functionalization of graphene-based materials using chemical moieties not only modify the electronic structure of the underlying graphene but also enable in limited enhancement of targeted properties.Surface modification of graphene-based materials using other nanostructures enhances the effective properties by minimally modifying the properties of pristine graphene backbone.In this pursuit,we have synthesized bio-inspired hierarchical nanostructures based on Ni–Co layered double hydroxide on reduced graphene oxide core–shells using template based wet chemical approach.The material synthesized have been characterized structurally and electrochemically.The fabricated dendritic morphology of the composite delivers a high specific capacity of 1056 Cg^(−1).A cost effective solid state hybrid supercapacitor device was also fabricated using the synthesized electrode material which shows excellent performance with high energy density and fast charging capability. | Karthik Kiran Sarigamala Shobha Shukla Alexander Struck Sumit Saxena | 2019 | Microsystems & Nanoengineering2019，5，1： | 2 |
| 8 | Pediatric pain,tools,and assessment显示文摘 | Sandra M Shobha M | 2000 | Journal of Peri-anesthesia Nursing2000，6，15： | 1 |
| 9 | Characterization of some aromatic dimethacrylates for dental composite applications显示文摘 | M SANKARAPANDIAN H. K SHOBHA S KALACHANDRA J. E MCGRATH D. F TAYLOR | 1997 | Journal of Materials Science: Materials in Medicine1997，，8： | 1 |
| 10 | HUMAN PANCREATIC GRAFT FISTULA EXOCRINE SUPPRESSION BY ORAL PANCREATIC ENZYMES1显示文摘 | Frank R. Burton Paul J. Garvin Shobha N. Joshi | 1989 | Transplantation1989，，： | 1 |
| 11 | Intake of Micronu- trient-Rich Foods in Rural Indian Mothers Is Associated with the Size of Their Babies at Birth: Pune Maternal Nutrition Study显示文摘 | Shobha R Chittaranjan SY Asawari K | 2001 | J Nutr2001，131，： | 1 |
| 12 | Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemicstroke:real world experience and a call for action显示文摘 | Bhatia R Hill MD Shobha N | 2010 | Stroke2010，41，10： | 1 |
| 13 | An Evaluation of Shade Differences Between Natural Anterior Teeth in Different Age Groups and Gender Using Commercially Available Shade Guides 显示文摘 | Shobha Rodrigues S Ramanand Shetty DR Prithviraj | 2012 | Journal of Indian Prosthodontic Society2012，12，4： | 1 |
| 14 | Do lacunar strokes bene- fit from thrombolysis? Evidence from the Registry of the Canadian Stroke Network显示文摘 | SHOBHA N FANG J HILL MD | 2013 | Int J Stroke2013，8，100： | 1 |
| 15 | Risk score for in-hospital ischemic stroke mortality derived and validated within the Get With the Guidelines-Stroke Program显示文摘 | Smith EE Shobha N Dai D | 2010 | Circulation2010，122，： | 1 |
| 16 | Upper GI mucosal effects of parecoxib sodium in healthy elderly subjects显示文摘 | Randall R Stoltz Stuart I Harris Michael E Kuss Diane LeComte Sheela Talwalker Shobha Dhadda Richard C Hubbard | 2002 | The American Journal of Gastroenterology2002，，1： | 1 |
| 17 | The revised FLACC observational pain tool: Improved reliability and validity for pain assessment in children with cognitive impairment 显示文摘 | Shobha M Terri VL Constance B | 2006 | Pediatric Anesthesia2006，16，： | 1 |
| 18 | Risk factors for adverse postop- erativeoutcomes inchildren presenting for cardiac surgery with up- perrespiratory tract infections显示文摘 | Shobha M Terri VL Monica S | 2003 | Anesthesiology2003，98，3： | 1 |
| 19 | Hypertrophic cranial pachy- meningitis in countries endemic for tuberculosis: diagnostic and therapeutic dilemmas 显示文摘 | Shobha N Mahadevan A Taly AB | 2008 | J Clin Neurosci2008，15，4： | 1 |
| 20 | Modification of guar galactomannan with the aid of Aspergillus niger pectinase显示文摘 | Shobha M S Vishu Kumar A B Tharanathan R N | 2005 | Carbohydrate Polymers2005，62，： | 1 |
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