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| 1 | Effect of Chlorophytum Borivilianum Santapau and Fernandes on Sexual Dysfunction in Hyperglycemic Male Rats显示文摘Objective:To investigate the effects of Chlorophytum borivilianum(CB) on sexual dysfunction, loss of body weight,and lack of libido in hyperglycemic rats induced with streptozotocin or alloxan.Methods: Wistar strain male albino rats were divided into five groups of six animals each:the control group(2% polyvinylpyrollidone solution),the streptozotocin control group(50 mg/kg),the alloxan control group(100 mg/kg), the streptozotocin + CB treated group(200 mg/kg),and the alloxan + CB treated group(200 mg/kg... | Mayank Thakur Shilpi Bhargava Werner Praznik Renate Loeppert Vinod K Dixit | 2009 | Chinese Journal of Integrative Medicine2009，15，6： | 3 |
| 2 | Comparative evaluation of microscopy,OptiMAL® and 18S rRNA gene based multiplex PCR for detection of Plasmodium falciparum & Plasmodium vivax from field isolates of Bikaner,India显示文摘Objective:To evaluate microscopy,OptiMAL? and multiplex PCR for the identification of Plasmodium falciparum(P.falciparum) and Plasmodium vivax(P.vivax) from the field isolates of Bikaner,Rajasthan(Northwest India).Methods:In this study,a multiplex PCR(P.falciparum and P.vivax) was further developed with the incorporation of Plasmodium malariae(P.malariae) specific primer and also a positive control.The performance of microscopy,plasmodium lactate dehydrogenase(pLDH) based malaria rapid diagnostic test OptiMAL? and 18S rRNA gene based multiplex PCR for the diagnosis of P.falciparum and P.vivax was compared.Results:The three species multiplex PCR if.falciparum,P.vivax and P.malariae) with an inbuilt positive control was developed and evaluated.In comparison with multiplex PCR,which showed the sensitivity and specificity of 99.36%(95%CI,98.11%-100.00%) and 100.00%(95%CI,100.00%-100.00%),the sensitivity and specificity of microscopy was 90.44%(95%CI,88.849-95.04%) and 99.22%(95% CI,97.71%-100.00%),and OptiMAL? was 93.58%(95%CI,89.75%-97.42%) and 97.69%(95%CI, 95.10%-100.00%).The efficiencies were 99.65%,95.10%and 95.45%for multiplex PCK.microscopy and OptiMAL?.respectively.Conclusions:Our results raise concerns over the overall sensitivities of microscopy and OptiMAL?,when compared to the multiplex PCR and thus stress the need for new molecular interventions in the accurate detection of the malarial parasites.This further highlights the fact that further developments are needed to improve the performance of rapid diagnostic tests at field level. | Deepak Pakalapati Shilpi Garg Sheetal Middha Abhishek Kochar Amit Kumar Subudhi Boopathi Pon Arunachalam Sanjay Kumar Kochar Vishal Saxena Pareek RP Jyoti Acharya Dhanpat Kumar Kochar Ashis Das | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，5： | 3 |
| 3 | Cold, salinity and drought stresses: An overview显示文摘 | Shilpi Mahajan Narendra Tuteja | 2005 | Archives of Biochemistry and Biophysics2005，，2： | 2 |
| 4 | Process optimization for the development of a functional beverage based on lactic acid fermentation of oats显示文摘 | Shilpi Gupta Sabrina Cox Nissreen Abu-Ghannam | 2010 | Biochemical Engineering Journal2010，，2： | 2 |
| 5 | Approaches for enhanced phytoextraction of heavy metals显示文摘 | Atul Bhargava Francisco F. Carmona Meenakshi Bhargava Shilpi Srivastava | 2012 | Journal of Environmental Management2012，，： | 2 |
| 6 | Studies on the Genotoxicity of Endosulfan in Different Tissues of Fresh Water Fish Mystus vittatus Using the Comet Assay显示文摘 | Shilpi Sharma N. S. Nagpure Ravindra Kumar Sanjay Pandey Satish K. Srivastava Poonam J. Singh P. K. Mathur | 2007 | Archives of Environmental Contamination and Toxicology2007，，4： | 1 |
| 7 | NARX neural network approach for the monthly prediction of groundwater levels in Sylhet Sadar, Bangladesh显示文摘Groundwater is important for managing the water supply in agricultural countries like Bangladesh. Therefore, the ability to predict the changes of groundwater level is necessary for jointly planning the uses of groundwater resources. In this study, a new nonlinear autoregressive with exogenous inputs(NARX) network has been applied to simulate monthly groundwater levels in a well of Sylhet Sadar at a local scale. The Levenberg-Marquardt(LM) and Bayesian Regularization(BR) algorithms were used to train the NARX network, and the results were compared to determine the best architecture for predicting monthly groundwater levels over time. The comparison between LM and BR showed that NARX-BR has advantages over predicting monthly levels based on the Mean Squared Error(MSE), coefficient of determination(R^2), and Nash-Sutcliffe coefficient of efficiency(NSE). The results show that BR is the most accurate method for predicting groundwater levels with an error of ± 0.35 m. This method is applied to the management of irrigation water source, which provides important information for the prediction of local groundwater fluctuation at local level during a short period. | Abdullah Al Jami Meher Uddin Himel Khairul Hasan Shilpy Rani Basak Ayesha Ferdous Mita | 2020 | Journal of Groundwater Science and Engineering2020，8，2： | 1 |
| 8 | Challenges in managing ST elevation myocardial infarction during the COVID-19 pandemic显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)may contribute to delayed presentations of acute myocardial infarction.Delayed presentation with late reperfusion is often associated with an increased risk of mechanical complications and adverse outcomes.Inherent delays are possible as every patient who is acutely sick is being considered a potential case or a career of COVID-19.Also,standardized personal protective equipment precautions are established for all members of the team,regardless of pending COVID-19 testing which might further add to delays.AIM To compare performance measures and clinical outcomes of all patients who presented to our facility with ST elevation myocardial infarction(STEMI)during the COVID-19 pandemic to same time cohort from 2019.METHODS All patients who presented to our facility with STEMI during the pandemic were compared to a matched cohort during the same time period in 2019.STEMI with unknown time of symptom onset and inpatient STEMI patients were excluded.Primary outcome was major adverse cardiac events(MACE)in-hospital and up to 14 d after STEMI,including death,myocardial infarction,cardiac arrest,or stroke.Significant differences among groups for continuous variables were tested through ANOVA,using SYSTAT,version 13.Chi-square tests of association were used to compare patient characteristics among groups using SYSTAT.Relative risk scores and associated tests for significance were calculated for discrete variables using MedCalc(MedCalc Software,Ostend,Belgium).RESULTS There was a significantly longer time interval from symptom onset to first medical contact(FMC)in the COVID-19 group(P<0.02).Time to first electrocardiogram,door-to-balloon time,and FMC to balloon time were not significantly affected.The right coronary artery was the most common culprit for STEMI in both the cohorts.Over 60%of patients had one or more obstructive(>50%)lesion(s)remote from the culprit site.In-hospital and 14 d MACE were more prevalent in the COVID-19 group(P<0.01 and P<0.001).CONCLUSION This single academic center study in the United States suggests that there is a delay in patients with STEMI seeking medical attention during the COVID-19 pandemic which could be translating into worse clinical outcomes. | Megan Smith Aniruddha Singh Douglas McElroy Shilpi Mittal Richard Pham | 2021 | World Journal of Cardiology2021，13，4： | 1 |
| 9 | Chromium removal from water by activated carbon developed from waste rubber tires显示文摘 | Vinod Kumar Gupta Imran Ali Tawfik A. Saleh M. N. Siddiqui Shilpi Agarwal | 2013 | Environmental Science and Pollution Research2013，，3： | 1 |
| 10 | Hybrid inorganic- organic proton exchange membranes contai- ning 1 H - 1,2,3 - Triazole moieties 显示文摘 | Shilpi Sanghi Mark Tuominen Bryan Coughlin E | 2010 | J Solid State I- onics2010，181，： | 1 |
| 11 | Antidiarrhoeal activity of the methanol extract of the barks of Xylocarpus moluccensis in castor oil- and magnesium sulphate-induced diarrhoea models in mice显示文摘 | S.J. Uddin J.A. Shilpi S.M.S. Alam M. Alamgir M.T. Rahman S.D. Sarker | 2005 | Journal of Ethnopharmacology2005，，1： | 1 |
| 12 | Acute toxicity bioassays of mercuric chloride and malathion on airbreathing fish Channa punctatus (Bloch) 显示文摘 | Sanjay P Ravindra K Shilpi S | 2005 | Ecotoxicology and Environmental Safety2005，61，1： | 1 |
| 13 | Salinity in drinking water and the risk of(pre)eclampsia and gestational hypertension in coastal bangladesh:a case-control study显示文摘 | Khan A E Scheelbeek P F Shilpi AB | 2014 | PLo S One2014，9，10： | 1 |
| 14 | Human islet amyloid polypeptide:A therapeutic target for the management of type 2 diabetes mellitus显示文摘Type 2 diabetes mellitus(T2DM)and other metabolic disorders are often silent and go unnoticed in patients because of the lack of suitable prognostic and diagnostic markers.The current therapeutic regimens available for managing T2DM do not reverse diabetes;instead,they delay the progression of diabetes.Their efficacy(in principle)may be significantly improved if implemented at earlier stages.The misfolding and aggregation of human islet amyloid polypeptide(hIAPP)or amylin has been associated with a gradual decrease in pancreatic b-cell function and mass in patients with T2DM.Hence,hIAPP has been recognized as a therapeutic target for managing T2DM.This review summarizes hIAPP's role in mediating dysfunction and apoptosis in pancreatic b-cells via induction of endoplasmic reticulum stress,oxidative stress,mitochondrial dysfunction,inflammatory cytokine secretion,autophagy blockade,etc.Furthermore,it explores the possibility of using intermediates of the hIAPP aggregation pathway as potential drug targets for T2DM management.Finally,the effects of common antidiabetic molecules and repurposed drugs;other hIAPP mimetics and peptides;small organic molecules and natural compounds;nanoparticles,nanobodies,and quantum dots;metals and metal complexes;and chaperones that have demonstrated potential to inhibit and/or reverse hIAPP aggregation and can,therefore,be further developed for managing T2DM have been discussed. | Pratiksha H.Roham Shreyada N.Save Shilpy Sharma | 2022 | Journal of Pharmaceutical Analysis2022，12，4： | 1 |
| 15 | Chromium removal by combining the magnetic properties of iron oxide with adsorption properties of carbon nanotubes 显示文摘 | Gupta V K Shilpi Agarwal Tawfik A Saleh | 2011 | Water Research2011，，45： | 1 |
| 16 | Embryological basis and clinical correlation of the rare congenital anomaly of the hu- man gall bladder: - 'the diverticulum' - a morphological study 显示文摘 | Jaba RaJguRul Shilpi Jain Satyam KhaRe | 2013 | J Clin Diagnos Res2013，10，： | 1 |
| 17 | EGLN1 involvement in high- altitude adaptation revealed through genetic analysis of extreme constitution types de fined in Ayurveda 显示文摘 | Shilpi A Sapna N Pankaj J | 2010 | PNAS2010，107，18： | 1 |
| 18 | Evaluation of iron oxide and aluminun oxide as potential arsenic(Ⅴ)adsorbents显示文摘 | YOUNGRAN J MAOHONG E SHILPI S | 2007 | Chemical Engineering and Processing2007，46，10： | 1 |
| 19 | Chromium re-moval by combining the magnetic properties of iron oxidewith adsorption properties of carbon nanotubes显示文摘 | V K Gupta Shilpi Agarwal Tawfik A Saleh | 2011 | Water Re-search2011，45，6： | 1 |
| 20 | Cold, salinity and drought stresses: an overview 显示文摘 | Shilpi M Narendra T | 2005 | Arch Biochem Biophys2005，444，： | 1 |
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