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173篇 您的检索式:作者名="SEIFERT F"
    题名 作者 年代 出处 被引量
1Role of Hox genes in stem cell differentiation显示文摘Hox genes are an evolutionary highly conserved gene family. They determine the anterior-posterior body axis in bilateral organisms and influence the developmental fate of cells. Embryonic stem cells are usually devoidof any Hox gene expression, but these transcription factors are activated in varying spatial and temporal patterns defining the development of various body regions. In the adult body, Hox genes are among others responsible for driving the differentiation of tissue stem cells towards their respective lineages in order to repair and maintain the correct function of tissues and organs. Due to their involvement in the embryonic and adult body, they have been suggested to be useable for improving stem cell differentiations in vitro and in vivo. In many studies Hox genes have been found as driving factors in stem cell differentiation towards adipogenesis, in lineages involved in bone and joint formation, mainly chondrogenesis and osteogenesis, in cardiovascular lineages including endothelial and smooth muscle cell differentiations, and in neurogenesis. As life expectancy is rising, the demand for tissue reconstruction continues to increase. Stem cells have become an increasingly popular choice for creating therapies in regenerative medicine due to their self-renewal and differentiation potential. Especially mesenchymal stem cells are used more and more frequently due to their easy handling and accessibility, combined with a low tumorgenicity and little ethical concerns. This review therefore intends to summarize to date known correlations between natural Hox gene expression patterns in body tissues and during the differentiation of various stem cells towards their respective lineages with a major focus on mesenchymal stem cell differentiations. This overview shall help to understand the complex interactions of Hox genes and differentiation processes all over the body as well as in vitro for further improvement of stem cell treatments in future regenerative medicine approaches.Anne Seifert David F Werheid Silvana M Knapp Edda Tobiasch 2015World Journal of Stem Cells2015,7,3:10
2Differential endogenous pain modulation in complex-regional pain syndrome 显示文摘Seifert F Kiefer G DeCol R 2009Brain2009,132,3:1
3Complex regional pain syndromes: new pathophysiological concepts and therapies 显示文摘Maihofner C Seifert F Markovic K 2010Eur J Neurol2010,17,5:1
4Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI显示文摘Chin C L Tovcimak A E Hradil V P Seifert T R Hollingsworth P R Chandran P Zhu C Z Gauvin D Pai M Wetter J Hsieh G C Honore P Frost J M Dart M J Meyer M D Yao B B Cox B F Fox G B 0,,02:1
5Analysis of long term dynamics of crowns of sessile oaks at the stand level by means of spatial statistics 显示文摘Longuetaud F Seifert T Leban J M 2008Forest Ecology and Manage- ment2008,256,20:1
6Complete substitution of Si for Ti in titanite Ca(Til-xSix)SiO5显示文摘Knoche R Angel R Seifert F 1998American Mineralogist1998,83,:1
7Enthalpy of mixing of liquid and undercooled liquid ternary and quaternary Cu-Ni-Si-Zr alloys显示文摘WITUSIEWICZ V T ARPSHOFEN I SEIFERT H J SOMMER F ALDINGER F 2002Journal of Alloys and Compounds2002,337,:1
8Apoplastie peroxidases and lignification in needles of Norway spruce (Picea abies L)显示文摘Polle A Otter T Seifert F 1994Plant Physiol1994,106,:1
9Membranes for bioartificial organ 显示文摘Seifert B Groth TH Fey-Lamprecht F 2000Int J Artif Organs2000,23,8:1
10Three-dimensional net work structure of quenched melts(glass) in the systems SiO2NaA102 SiO2-CaA1204 and SiO2-MgAI204显示文摘SEIFERT F MYSEN B O VIRGO D 1982Amer Mineral1982,67,:1
11Mechanisms of neuropathic pain显示文摘Nickel F T Seifert F Lanz S 2012Eur Neuropsychopharmacol2012,22,2:1
12Quality of care of a pharmacist managed diabetes service compared to usual care in an indigent clinic显示文摘IronsBK Seifert C F Horton N A 2008Diabetes Teehnol Ther2008,10,3:1
13Experimental investigation and thermodynamic calculation of the Al-Mg-Zn system 显示文摘LIANG P TARFA T ROBINSON J A WAGNER S OCHIN P HARMELIN M G SEIFERT H J LUKAS H L ALDINGER F 1998Thermochimica Acta1998,314,12:1
14Injection pain of rocuronium and vecuronium is evoked by direct activation of noeiceptive nerve endings显示文摘Blunk JA Seifert F Schmelz M 2003Eur J Anaesth2003,20,24:1
15Adenoma and carcinoma of the duodenum and papilla of Vater: a clinicupathologic study 显示文摘Seifert E Schulte F Stolte M 1992J Am J Gastroenterol1992,87,1:1
16On the crystal structure and solubility range on the ternary phase in the Mg-Al-Zn system 显示文摘DONNADIEU P QUIVY A TARFA T OCHIN P DEZELLUS A HARMELIN M G LIANG P LUKAS H L SEIFERT H J ALDINGER F EFFENBERG G 1997Z Metallkd1997,88,12:1
17Metabolic alterations in the dorsolateral prefrontal cortex after treatment with high - frequency re-petitive transcranial magnetic stimulation in patients with unipolar major depression 显示文摘Luborzewski A Schubert F Seifert F 2007J Psychiatr Res2007,41,7:1
18TRPA 1 and TRPM8 activation in humans:effects of cinnamaldehyde and menthol 显示文摘Namer B Seifert F Handwerker HO 2005Neuroreport2005,16,9:1
19Compressibility effects in two-phase flow显示文摘TANGREN R F DODGE C H SEIFERT H S 1949Journal of Applied Physics1949,20,7:1
20A delphi method expert survey to derive standards for flood damage data collection显示文摘ELMER F SEIFERT I KREIBICH H 2010Risk Anal2010,30,1:1
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