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| 1 | Non-alcoholic fatty liver disease and the metabolic syndrome:An update显示文摘Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries, subsequently increasing the risk for developing the metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). NAFLD is estimated to affect approximate 30% of the general US population and is considered the hepatic manifestation of the metabolic syndrome. Recent findings linking the components of the metabolic syndrome with NAFLD and the progression to nonalcoholic steatohepatitis (NASH) will be reviewed; in particular, the role of visceral adipose tissue, insulin resistance, and adipocytokines in the exacerbation of these conditions. While no therapy has been proven effective for treating NAFLD/NASH, common recommendations will be discussed. | R Scott Rector John P Thyfault Yongzhong Wei Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 60 |
| 2 | Nonalcoholic fatty liver disease and mitochondrial dysfunction显示文摘Nonalcoholic fatty liver disease (NAFLD) includes hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD is the most common liver disorder in the United States and worldwide. Due to the rapid rise of the metabolic syndrome, the prevalence of NAFLD has recently dramatically increased and will continue to increase. NAFLD has also the potential to progress to hepatocellular carcinoma (HCC) or liver failure. NAFLD is strongly linked to caloric overconsumption, physical inactivity, insulin resistance and genetic factors. Although significant progress in understanding the pathogenesis of NAFLD has been achieved in years, the primary metabolic abnormalities leading to lipid accumulation within hepatocytes has remained poorly understood. Mitochondria are critical metabolic organelles serving as 'cellular power plants'. Accumulating evidence indicate that hepatic mitochondrial dysfunction is crucial to the pathogenesis of NAFLD. This review is focused on the significant role of mitochondria in the development of NAFLD. | Yongzhong Wei R Scott Rector John P Thyfault Jamal A Ibdah | 2008 | World Journal of Gastroenterology2008,14,2: | 32 |
| 3 | Volumetric Analysis Predicts Hepatic Dysfunction in Patients Undergoing Major Liver Resection显示文摘 | Margo Shoup Mithat Gonen Michael D’Angelica William R Jarnagin Ronald P DeMatteo Lawrence H Schwartz Scott Tuorto Leslie H Blumgart Yuman Fong | 2003 | Journal of Gastrointestinal Surgery2003,,3: | 2 |
| 4 | Clostridium difficile Enteritis after Colectomy显示文摘 | Causey M Wayne Spencer Michael P Steele Scott R | 2009 | The American Surgeon2009,,12: | 2 |
| 5 | T lymphocyte subpopulations in idiopathic thrombocytopenic purpura (ITP) 显示文摘 | Scott C S Wheeler R Ford P | 1983 | Scand J Haematol1983,40,: | 1 |
| 6 | Role of the hypoxia sensing system, acidity and reproductive hormomes in the viability of vascular endothelial growth factor induction in human breast carcinoma cell lines显示文摘 | Scott P Gleadle M Bicknell R | 2002 | Int Cancer2002,75,5: | 1 |
| 7 | Gold and trace element zonation in pyrite using a laser imaging technique: Implications for the timing of gold in orogenic and Carlin- style sediment- hosted deposits 显示文摘 | R R Large L Danyushevsky C Hollit V Maslennikov S Meffer S Gilbert S Bull R Scott P Emsbo H Thomas B Singh J Foster | 2009 | Economic Geology2009,104,5: | 1 |
| 8 | Calcium anidotrihydroborate:a hydrogen storage material显示文摘 | Diyabalanage H V K Shrestha R P Semelsberger TA Scott B L Bowden M E Davis B L Burrell A K | | 0,,47: | 1 |
| 9 | Cesarean delivery for fetal distress: Rate and risk factors 显示文摘 | CHAUHAN S P MAGANN E F SCOTT J R | 2003 | Obstet Gynecol Surv2003,58,5: | 1 |
| 10 | Total knee arthroplasty with the PFC system results at a minimum of ten years and survivorship analysis 显示文摘 | Schai P A Thornhill T S Scott R D | 1998 | J Bone Joint Surg Br1998,80,5: | 1 |
| 11 | The role of betaamyloid precursor protein (beta-APP) staining in the neuropathologic evaluation of sudden infant death and in the initiation of clinical investigations of subsequent siblings显示文摘 | Byard R W Blumbergs P Scott G | 2006 | Am J Forensic Med and Pathology2006,27,4: | 1 |
| 12 | PKI Elliptic Curve Cryptography,and Digital Signatures显示文摘 | William J C Edward P D Scott A R | 1999 | Computers and Security1999,18,: | 1 |
| 13 | Incorporation of polarization into the DIRSIG synthetic image generation model 显示文摘 | Jason P M eyers John R Schott Scott D Brown | 2002 | Proceedings of SPIE(S0277-786X)2002,4816,: | 1 |
| 14 | Comparison of column phases for separation of derivatized trichothecenes by capillary gas chromatography显示文摘 | Scott P M Kanhere S R | 1986 | Journal of Chromatography1986,368,2: | 1 |
| 15 | percutaneous transthoraeic needle aspiration biopsy:a comprehensive review of its current role in the diagnosis and treatment of lung lumors显示文摘 | Larseheid R C Thorpe P E Scott W J | 1998 | Chest1998,114,3: | 1 |
| 16 | The effects of delayed sowing and weather on growth,development and yield of winter oil seed rapeseed显示文摘 | MENDHAM N J SHIPWAY P A SCOTT R K | 1981 | Agric Sci Camb1981,96,: | 1 |
| 17 | A procedure for miniseale preparation of Pyricularia grisea DNA显示文摘 | SCOTT R P ZEIGLER R S NELSON R J | 1993 | International Rice Research Notes1993,18,1: | 1 |
| 18 | Prion protein biology显示文摘 | PRUSINER S P SCOTT M R DEARMOND S J | 1998 | Ce111998,93,: | 1 |
| 19 | Facts and recommendations about total homocysteine determinations:an expert opinion显示文摘 | Refsum H Smith A D Ueland P M Nexo E Clarke R McPartlinJ Johnston C Engbaek F SchneedeJ McPartlin C Scott J M | 2004 | Clinical Chemistry2004,50,1: | 1 |
| 20 | Gaschromatography with electron cap ture and masssp ectrom etricdetection of deoxyn-ivalenol in wheat and othergrains显示文摘 | SCOTT P M LAU P Y KANHERE S R | 1981 | JAssoc Off AnalChem1981,64,: | 1 |