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8篇 您的检索式:作者名="SATYA H"
    题名 作者 年代 出处 被引量
1The evolution of manufacturing cells: An action research study显示文摘Satya Chakravorty S Douglas N H 2008European J of Operational Research2008,188,1:1
2Nonlinear time/cost tradeoff models in project management显示文摘Richard D John H William V Henning G Satya V 1995Computer and Industrial Engineering1995,28,2:1
3Gas diffusion behavior of coal and its impact on production from coal bed methane reservoirs显示文摘MALLIKARJUN P SATYA H LIU S M 2011International Journal of Coal Geology2011,86,4:1
4Influence of gas production induced volumetric strain on permeability of coal 显示文摘Satya H Chen G L 1997Geotechnical and Geological Engineering1997,15,4:1
5The evolution of manufacturing cells:an action research study显示文摘SATYA S C DOUGLAS N H 2008European Journal of Operational Research2008,188,1:1
6Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion显示文摘Satya D Sarah C Sara H 0,,03:1
7CCR6 is required for IL-23-induced psoriasis-like inflammation in mice显示文摘Hedrick Michael N Lonsdorf Anke S Shirakawa Aiko-Konno Lee Chyi-Chia Richard Liao Fang Singh Satya P Zhang Hongwei H Grinberg Alexander Love Paul E Hwang Sam T Farber Joshua M 2009Journal of Clinical Investigation2009,,8:1
8Pathway-selective suppression of chemokine receptor signaling in B cells by LPS through downregulation of PLC-b2显示文摘Lymphocyte activation leads to changes in chemokine receptor expression.There are limited data,however,on how lymphocyte activators can alter chemokine signaling by affecting downstream pathways.We hypothesized that B cell-activating agents might alter chemokine responses by affecting downstream signal transducers,and that such effects might differ depending on the activator.We found that activating mouse B cells using either anti-IgM or lipopolysaccharide(LPS)increased the surface expression of CCR6 and CCR7 with large increases in chemotaxis to their cognate ligands.By contrast,while anti-IgM also led to enhanced calcium responses,LPS-treated cells showed only small changes in calcium signaling as compared with cells that were freshly isolated.Of particular interest,we found that LPS caused a reduction in the level of B-cell phospholipase C(PLC)-b2 mRNA and protein.Data obtained using PLC-b22/2 mice showed that the b2 isoform mediates close to one-half the chemokine-induced calcium signal in resting and anti-IgM-activated B cells,and we found that calcium signals in the LPS-treated cells were boosted by increasing the level of PLC-b2 using transfection,consistent with a functional effect of downregulating PLC-b2.Together,our results show activator-specific effects on responses through B-cell chemokine receptors that are mediated by quantitative changes in a downstream signal-transducing protein,revealing an activity for LPS as a downregulator of PLC-b2,and a novel mechanism for controlling chemokine-induced signals in lymphocytes.Aiko-Konno Shirakawa Fang Liao Hongwei H Zhang Michael N Hedrick Satya P Singh Dianqing Wu Joshua M Farber 2010Cellular & Molecular Immunology2010,7,6:0
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