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19篇 您的检索式:作者名="S.Brown"
    题名 作者 年代 出处 被引量
1Survival Outcomes Following Liver Transplantation (SOFT) Score: A Novel Method to Predict Patient Survival Following Liver Transplantation显示文摘A.Rana M. A.Hardy K. J.Halazun D. C.Woodland L. E.Ratner B.Samstein J. V.Guarrera R. S.Brown Jr J. C.Emond 2008American Journal of Transplantation2008,,12:2
2Hypothermic Machine Preservation in Human Liver Transplantation: The First Clinical Series显示文摘J. V.Guarrera S. D.Henry B.Samstein R.Odeh‐Ramadan M.Kinkhabwala M. J.Goldstein L. E.Ratner J. F.Renz H. T.Lee R. S.Brown Jr. J. C.Emond 2010American Journal of Transplantation2010,,2:1
3Endoscopic morphological anticipation of submucosal invasion in flat and depressed colorectal lesions: clinical implications and subtype analysis of the kudo type V pit pattern using high‐magnification‐chromoscopic colonoscopy显示文摘D. P.Hurlstone S. S.Cross I.Adam A. J.Shorthouse S.Brown D. S.Sanders A. J.Lobo 2004Colorectal Disease2004,,5:1
4Current methods of transfer of young people with Type 1 diabetes to adult services显示文摘S.Kipps T.Bahu K.Ong F. M.Ackland R. S.Brown C. T.Fox N. K.Griffin A. H.Knight N. P.Mann H. A. W.Neil H.Simpson J. A.Edge D. B.Dunger 2002Diabetic Medicine2002,,8:1
5The Survival Impact of Liver Transplantation in the MELD Era, and the Future for Organ Allocation and Distribution显示文摘Robert S.Brown John R.Lake 2005American Journal of Transplantation2005,,2:1
6Severe fibrosis in hepatitis C virus‐infected patients is associated with increased activity of the mannan‐binding lectin (MBL)/MBL‐associated serine protease 1 (MASP‐1) complex显示文摘K. S.Brown M. J.Keogh N.Tagiuri M. J.Grainge J. S.Presanis S. D.Ryder W. L.Irving J. K.Ball R. B.Sim T. P.Hickling 2006Clinical & Experimental Immunology2006,,1:1
7Dynamic and ther-modynamic changes in mean and extreme precipi-tation under changed climate显示文摘Emori S S.Brown 0,,17:1
8查看详情显示文摘R.Feyerherm E.Dudzik A.U.B.Wolter S.Valencia O.Prokhnenko A.Maljuk S.Landsgesell N.Aliouane L.Bouchenoire S.Brown and D.N.Argyriou 0,,13:1
9Achieving R0 resection in the colorectum using endoscopic submucosal dissection显示文摘D. P.Hurlstone R.Atkinson D. S.Sanders M.Thomson S. S.Cross S.Brown 2007Br J Surg2007,,12:1
10Root proliferation and seed yield in response to spatial heterogeneity of below‐ground competition显示文摘Erin E.O’Brien MordechaiGersani Joel S.Brown 2005New Phytologist2005,,2:1
11Tragedy of the commons as a result of root competition显示文摘MordechaiGersani Joel s.Brown Erin E.O’Brien Godfrey M.Maina ZvikaAbramsky 2001Journal of Ecology2001,,4:1
12Lung mi-cronodules:automated method for detection at thin-section CT-initial experience显示文摘Matthew S.Brown Jonathan G.Goldin Robert D.Suh 0,,:1
13伺服装置在包装设备中的位置——确保伺服装置在包装生产线上高效、可靠地运行显示文摘灵活性驱使更多的生产商将眼光转向伺服驱动的包装生产线上,但对有关验证(validation)和基于个人计算机(PC-base)控制的“蓝屏死机”问题却仍然存在着顾虑。Alan S.Brown 2008流程工业2008,,15:0
14回旋加速器有多大?显示文摘本文用氢原子的Bohr半径a0及精细结构常数aLowell S.Brown 马美仲 1991大学物理1991,10,11:0
15Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry显示文摘Mannan-binding lectin(MBL)is a soluble innate immune protein that binds to glycosylated targets.MBL acts as an opsonin and activates complement,contributing to the destruction and clearance of infecting microorganisms.Hepatitis C virus(HCV)encodes two envelope glycoproteins E1 and E2,expressed as non-covalent E1/E2 heterodimers in the viral envelope.E1 and E2 are potential ligands for MBL.Here we describe an analysis of the interaction between HCV and MBL using recombinant soluble E2 ectodomain fragment,the full-length E1/E2 heterodimer,expressed in vitro,and assess the effect of this interaction on virus entry.A binding assay using antibody capture of full length E1/E2 heterodimers was used to demonstrate calcium dependent,saturating binding of MBL to HCV glycoproteins.Competition with various saccharides further confirmed that the interaction was via the lectin domain of MBL.MBL binds to E1/E2 representing a broad range of virus genotypes.MBL was shown to neutralize the entry into Huh-7 cells of HCV pseudoparticles(HCVpp)bearing E1/E2 from a wide range of genotypes.HCVpp were neutralized to varying degrees.MBL was also shown to neutralize an authentic cell culture infectious virus,strain JFH-1(HCVcc).Furthermore,binding of MBL to E1/E2 was able to activate the complement system via MBL-associated serine protease 2.In conclusion,MBL interacts directly with HCV glycoproteins,which are present on the surface of the virion,resulting in neutralization of HCV particles.Kristelle S.Brown Michael J.Keogh Ania M.Owsianka Richard Adair Arvind H.Patel James N.Arnold Jonathan K.Ball Robert B.Sim Alexander W.Tarr Timothy P.Hickling 2010Protein & Cell2010,1,7:0
16Hybrid solar cells constructed of macroporous n-type GaP coated with PEDOT:PSS显示文摘Hybrid organic–inorganic solar cell devices were fabricated utilizing macroporous n-type Ga P and poly(3,4-ethylenedioxythiophene):poly(4-styrene sulfonate)(PEDOT:PSS).The high-aspect ratio structures of the macroporous Ga P resulted in higher photocurrent and external quantum yield as a function of wavelength.Photocurrent–voltage measurements as a function of light intensity revealed information on the dependence of short-circuit current(Jsc) and open-circuit voltage(Voc) on light intensity.Under 1.0 Sun illumination,hybrid macroporous Ga P/PEDOT:PSS devices showed Jscof2.34 m A cmà2,Vocof 0.95 V,fill factor of 0.54,and overall efficiency of 1.21%.The extent of the influence of dopant density of Ga P on hybrid device performance was probed with current density–voltage measurements.The addition of a gold nanoparticle coating on macroporous Ga P prior to PEDOT:PSS coating showed increased device performance,with overall efficiency of 1.81%.Gold-modified planar Ga P/PEDOT:PSS showed decreased Jscand Vocvalues and lower external quantum yield over all wavelengths.Zhijie Wang Elizabeth S.Brown Stephen Maldonado 2015Chinese Chemical Letters2015,26,4:0
17Household perceptions and subjective valuations of indoor residual spraying programmes to control malaria in northern Uganda显示文摘Background:Insecticide-based tools remain critical for controlling vector-borne diseases in Uganda.Securing public support from targeted populations for such tools is an important component in sustaining their long-run effectiveness.Yet little quantitative evidence is available on the perceived benefits and costs of vector control programmes among targeted households.Methods:A survey was administered to a clustered random sample of 612 households in Gulu and Oyam districts of northern Uganda during a period of very high malaria transmission and following a pilot indoor residual spray(IRS)programme.A discrete choice experiment was conducted within the survey,in which respondents indicated their preferences for different IRS programmes relative to money compensation in a series of experimentally controlled,hypothetical choice sets.The data were analysed using conditional logit regression models to estimate respondents’willingness to accept(WTA)some amount of money compensation in lieu of foregone malaria risk reductions.Latent class models were used to analyse whether respondent characteristics predicted WTA.Results:Average WTA is estimated at$8.94 annually for a 10%reduction in malaria risk,and additional co-benefits of IRS were estimated to be worth on average$54–$56(depending on insecticide type)per round of IRS.Significant heterogeneity is observed:Four in five household heads in northern Uganda have high valuations for IRS programmes,while the remaining 20%experience costly side effects of IRS(valued at between$2 and$3 per round).Statistically significant predictors of belonging to the high-value group include respondent gender,mean age of household members,participation in previous IRS,basic knowledge of mosquito reproduction,and the number of mosquito nets owned.Proxies for household income and wealth are not found to be statistically significant predictors of WTA.Conclusions:This study suggests that the majority of people in areas of high malaria transmission like northern Uganda place a high value on vector control programmes using IRS.However,there is significant heterogeneity in terms of the perceived side effects(positive and negative).This has implications for sustaining public support for these programmes in the long-term.Zachary S.Brown Randall A.Kramer David Ocan Christine Oryema 2016Infectious Diseases of Poverty2016,5,1:0
18Increased proportion of alcohol-related trauma in a South London major trauma centre during lockdown:A cohort study显示文摘Purpose:Alcohol has been associated with 10%—35%trauma admissions and 40%trauma-related deaths globally.In response to the COVID-19 pandemic,the United Kingdom entered a state of'lockdown'on March 23,2020.Restrictions were most significantly eased on June 1,2020,when shops and schools re-opened.The purpose of this study was to quantify the effect of lockdown on alcohol-related trauma admissions.Methods:All adult patients admitted as'trauma calls'to a London major trauma centre during April 2018 and April 2019(pre-lockdown,n=316),and 1st April—31st May 2020(lockdown,n=191)had electronic patient records analysed retrospectively.Patients’blood alcohol level and records of intoxication were used to identify alcohol-related trauma.Trauma admissions from pre-lockdown and lockdown cohorts were compared using multiple regression analyses.Results:Alcohol-related trauma was present in a significantly higher proportion of adult trauma calls during lockdown(lockdown 60/191(31.4%),vs.pre-lockdown 62/316(19.6%);(odds ratio(OR):0.83,95%CI:0.38—1.28,p<0.001).Lockdown was also associated with increased weekend admissions of trauma(lockdown 125/191 weekend(65.5%)vs.pre-lockdown 179/316(56.7%);OR:0.40,95%CI:0.79 to-0.02,p=0.041).No significant difference existed in the age,gender,or mechanism between pre-lockdown and lockdown cohorts(p>0.05).Conclusions:The United Kingdom lockdown was independently associated with an increased proportion of alcohol-related trauma.Trauma admissions were increased during the weekend when staffing levels are reduced.With the possibility of further global'waves'of COVID-19,the long-term repercussions of dangerous alcohol-related behaviour to public health must be addressed.Oliver S.Brown Toby O.Smith Andrew J.Gaukroger Prodromos Tsinaslanidis Caroline B.Hing 2022Chinese Journal of Traumatology2022,25,5:0
19关于新战略环境的思考显示文摘全球反恐战争影响了学者对新时期战略环境的探讨。近年来,一批学者出版了一些思维独特、资料翔实、视角广阔的著作,引起了各界的广泛关注。Thomas P.M.Barnett的《五角大楼的新地图》认为,全球化使未来世界充满希望,强国之间的大战已成过去,美国应发挥核心作用以有效地管理世界,应对各种贫穷、腐败、有组织犯罪、极端主义和恐怖主义等;John S.Brown 张建 2006世界知识2006,,3:0
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