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| 1 | Function of apoptosis and expression of the proteins Bcl-2,p53 and C-myc in the development of gastric cancer显示文摘INTRODUCTIONIn China ,the incidence and mortality of gastric cancer rank the second among all cancers. Recent development of cancer [1-20].The aim of this study was investigat the insight of apoptosis and bcl-2, p53 and C-myc protein expression in the development of gastric cancer . | An Gao Xu Shao Guang Li Ji Hong Liu Ai Hua Gan Research Laboratory of Digestive Disease,Huizhou Central People’s Hospital,Huizhou 516001,Guangdong Province,ChinaDr.An Gao Xu graduated from Guangdong Medical College in 1984.He is an associate physician-in-chief,specializing in the research and treatment of gastrointestinal and liver tumors.He has published 24 papers and 1 book. | 2001 | World Journal of Gastroenterology2001，7，3： | 91 |
| 2 | A randomized controlled clinical trial on the treatment of Thymosin-a1 versus interferon-α in patients with hepatitis B显示文摘INTRODUCTIONChronic hepatitis B virus (HBV) infection is a serious problem because of its world wide distribution and possible adverse sequelae ,such as cirrhosis and hepatocellular carcinoma .The World Health Organization estimates that HBV has infected mord than 350 million people worldwide ,and up to 20% of them will become chromic carricrs and will be at significant risk for cirrhosis and HCC .The ultimate goal of the therapy for chronic hepatitis B is to prevent progression to cirrhosis and to prevent development of HCC. | Jing You Lin Zhuang Bao Zhang Tang Wei Bo Yang Su Ying Ding Wu Li Rong Xue Wu Hong Li Zhang Yan Mei Zhang Shao Ming Yan Lu Zhang ~1Department of Infectious Diseases,The First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan Province,China ~2Departrnent of Hepatology,Kunming Third Municipal People’s Hospital,Kunming 650041,Yunnan Province,China | 2001 | World Journal of Gastroenterology2001，7，3： | 48 |
| 3 | Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment显示文摘这篇文章重游在象急躁的肠症候群( IBS )那样的精神病理学和功能的胃肠的混乱之间的连接,讨论抗抑郁剂的合理使用以及非药理学来临到 IBS 的管理,并且从知识的现在的状态基于一个学科交差的观点为 IBS 的处理建议指南。精神病学的混乱上的相关出版文学,特别躯体化混乱在 IBS 的上下文,并且为管理的文学提供方向被考察,并且新方向在文学从调查结果被提供。IBS 是有为它的临床的演讲负责的各种各样的潜在的机制的异构的症候群。IBS 与在另外的机关系统的精神病学的问题, unexplained 症状,和功能的症候群典型地是复杂的。没有表明的原因,大多数 IBS 病人有多重抱怨,并且这些症状能包含除肠以外的系统,例如骨头和关节(fibromyalgia,颞下颌关节症候群) ,心(非心脏的胸痛) ,脉管(绝经后的症候群) ,并且大脑(焦虑,消沉) 。大多数 IBS 病人没有精神病学的病伴随他们的 somatoform (当医药混乱不在时的物理症状) 的精神分析形式(当精神病学的混乱不在时的心理抱怨) 的本身,而是一个范围症状抱怨。作为精神病学的病人把 IBS 病人标记不是正确的(除了有真躯体化的那些更困难的病人混乱) 。治疗的一个模式是不大可能的普遍有效或解决大多数症状。心理疗法或认知行为的治疗的技术能允许 IBS 病人与他们的病更乐意地处理。特定的事件压抑或焦虑混乱能为那些条件作为适当被管理。设计改进焦虑或消沉的药不为在 IBS 的精神病学的抱怨是一致地有用的,因为听起来类似于在精神病学的混乱看见的那些的精神分析形式症状不能与 IBS 在病人有一样的意义。 | Carol S North Barry A Hong David H Alpers | 2007 | World Journal of Gastroenterology2007，13，14： | 17 |
| 4 | P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte- endothelial adhesion and promotes neurovascular injury during septic encephalopathy显示文摘 | Huan Wang Ling-Juan Hong Ji-Yun Huang Quan Jiang Rong-Rong Tao Chao Tan Nan-Nan Lu Cheng-Kun Wang Muhammad M Ahmed Ying-Mei Lu Zhi-Rong Liu Wei-Xing Shi En-Yin Lai Christopher S Wilcox Feng Han | 2015 | Cell Research2015，25，6： | 16 |
| 5 | Rocky Desertification Risk Zone Delineation in Karst Plateau Area:A Case Study in Puding County,Guizhou Province显示文摘Karst rocky desertification is a geo-ecological problem in Southwest China.The rocky desertification risk zone delineation could be used as a guide for the regional and hierarchical rocky desertification management and prevention.We chose the middle and lower reaches of the Houzhai underground basin on the karst plateau in Puding County, Guizhou Province, China as the study area and selected land use type, elevation, slope, aspect, lithology and settlement buffer as the main driving factors of the rocky desertification.The potential risk of rocky desertification was quantified with the factor-weights union method and statistical analysis method.Five grades of rocky desertification risk were delineated based on Geographic Information System.The extremely low, low, moderate, high and extremely high rocky desertification risk zones accounted for 5.01%, 44.17%, 33.92%, 15.59% and 1.30%, respectively.As a whole, the rocky desertification risk level was moderate because the area of low and moderate rocky desertification risk zones occupied 78.09% of the study area.However, more than half of the area(about 50.81%) was predicted to have moderate rocky desertification risk and above, indicating that the study area was subject to rocky desertification.Rocky desertification risk was higher in the southeast and lower in the northwest of the study area.Distinct differences in the distribution of rocky desertification risk zones corresponding to different factors have been found. | ZHANG Panpan HU Yuanman XIAO Duning LI Xiuzhen YIN Jie HE Hong S | 2010 | Chinese Geographical Science2010，20，1： | 15 |
| 6 | THE IMPROVEMENT OF ELECTRON FIELD EMISSION FROM AMORPHOUS CARBON FILMS DUE TO HYDROGEN PLASMA CHEMICAL ANNEALING EFFECT显示文摘Hydrogenated amorphous carbon films were fabricated by using layer-by-layer deposition method and hydrogen dilution method in a small d.c.-assisted plasma enhanced chemical vapor deposition system. It was found that the hydrogen plasma treatment could change the sp2/sp3 ratio to some extent by chemical etching. The improvements of field emission characteristics were observed compared with that from conventionally deposited a-C films, which can be attributed to the large field enhancement effect due to the inhomogeneous distribution of nanometer scale sp2 clusters and the reduction of the surface emission barrier due to the hydrogen termination. | J. Xu, X.H. Huang, L. Wang, W. Li and K.J. Chen (National Laboratory of Solid State Microstructures and Departmeat of Physics, Nanjing University, Nanjing 210093, China) J.B. Xu (Department of Electronic Engineering, The Chinese University of Hong Kong, S | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，6： | 15 |
| 7 | Proteome analysis of hepatocellular carcinoma by laser capture microdissection显示文摘 | Ai J Tan Y Ying W Hong Y Liu S Wu M Qian X Wang H | 2006 | 第二军医大学学报2006，27，5： | 14 |
| 8 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 9 | Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry显示文摘AIM:To elucidate the underlying mechanisms of metastasis and to identify the metabolomic markers of gastric cancer metastasis.METHODS:Gastric tumors from metastatic and nonmetastatic groups were used in this study.Metabolites and different metabolic patterns were analyzed by gas chromatography,mass spectrometry and principal components analysis (PCA),respectively.Differentiation performance was validated by the area under the curve (AUC) of receiver operating characteristic curves.RESULTS:Twenty-nine metabolites were differentially expressed in animal models of human gastric cancer.Of the 29 metabolites,20 were up-regulated and 9 were down-regulated in metastasis group compared to non-metastasis group.PCA models from the metabolite profiles could differentiate the metastatic from the nonmetastatic specimens with an AUC value of 1.0.These metabolites were mainly involved in several metabolic pathways,including glycolysis (lactic acid,alaline),serine metabolism (serine,phosphoserine),proline metabolism (proline),glutamic acid metabolism,tricarboxylic acid cycle (succinate,malic acid),nucleotide metabolism (pyrimidine),fatty acid metabolism (docosanoic acid,and octadecanoic acid),and methylation(glycine).The serine and proline metabolisms were highlighted during the progression of metastasis.CONCLUSION:Proline and serine metabolisms play an important role in metastasis.The metabolic profiling of tumor tissue can provide new biomarkers for the treatment of gastric cancer metastasis. | Jin-Lian Chen,Jun-Duo Hu,Jing Fan,Jing Hong,Department of Gastroenterology,Shanghai Sixth People’s Hospital,Shanghai Jiao Tong University,Shanghai 200233,China Hui-Qing Tang,Jian-Zhong Gu,Shanghai Laboratory Animal Center,Chinese Academy of Sciences,Shanghai 201615,China | 2010 | World Journal of Gastroenterology2010，16，46： | 11 |
| 10 | Percutaneous transhepatic metal versus plastic biliary stent in treating malignant biliary obstruction: a multiple center investigation显示文摘OBJECTIVE: To compare the efficacy of metal versus plastic biliary stent implantation in the treatmentof malignant biliary obstruction.METHODS: Percutaneous transhepatic self-expandable metal stent (MS, n=61) and 10F plastic stent(PS, n=34) were placed in 95 patients with malignant biliary obstruction in three hospitals of Guangdongprovince. All patients were followed up until death or at least one year after the procedure. Kaplan-Meieranalysis was used to compare the survival of the patients and the rates of stent patency.RESULTS: The 30-day mortality rate was lower in the MS group (6/61, 9.8%) than in the PS group(9/34, 26.5%, P<0.05). The 30-day reobstruction rate and the complication rate were 15.0%, 16.4%in the MS group and 32. 4%, 29. 4% in the PS group, respectively (P<0. 01). The median patencyperiod of stents and median survival period of the patients were 230 days, 224 days in the MS group and90 days, 94 days in the PS group, respectively (P<0. 01).CONCLUSION: Metal stent is clinically superior to plastic stent in the treatment of malignant biliaryobstruction. | Yuan-Xing Guo Yan-Hao Li Yong Chen Ping-Yan Chen Peng-Fei Luo Yong Li Hong Shan Zai-Bo Jiang the Department of Interventional Radiology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China Department of Medical Statistics, First Military Medical University, Guangzhou 510515, China Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080, China Department of Radiology, Third Affiliated Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou 510630, China | 2003 | Hepatobiliary & Pancreatic Diseases International2003，2，4： | 8 |
| 11 | 美蓝染色放大电子结肠镜观察结肠息肉与组织病理学的关系显示文摘目的:研究美蓝染色后用放大电子结肠镜观察结肠息肉的微细结构类型与组织病理学的关系。方法:使用0.5%美蓝对电子结肠镜检查到有息肉的部位进行息肉及邻近的黏膜进行染色,然后用放大电子结肠镜观察。按Kudo’s标准记录正常结肠黏膜和息肉,然后行活检或息肉电切术,以便组织病理学评价。结果:本组共67人,普通电子结肠镜检查发现息肉180颗,经美蓝染色后又发现了1-3mm大小的息肉90颗,共计270颗息肉。放大结肠镜可明显提高腺瘤性病变的检出率,P<0.001。270颗病变的隐窝类型分为6种,呈Ⅱ型者2颗(0.7%);Ⅲ_s型203颗(75.2%);Ⅲ_L型49颗(18.1%),其中伴有轻、中度非典型增生者7颗;Ⅳ型11颗(4.1%),伴有轻度非典型增生者2颗、黏膜癌1颗(9.1%),Ⅴ_n共5颗(1.9%),伴有中度非典型增生者1颗,黏膜癌2颗(40%)。本组息肉均进行了电切术。结论:美蓝染色后用放大电子结肠镜可清晰地观察到结肠隐窝,其大小一致,呈圆形或椭圆形;诊断为腺瘤性息肉与病理组织学的符合率为96.7%,可明显提高息肉的检出率,并可鉴别电切息肉术后残留的基底部是否残留腺瘤组织或癌灶。 | Lu Su Hong-Zhen Pan Jing-Biao Weng Yi-Hua Xu Fang Chen Mei-Yan Hong Department of Digestive Endoscopy, The Worker’s Hospital of Hainan Province, Haikou 570311, Hainan Province, China | 2003 | 世界华人消化杂志2003，11，8： | 8 |
| 12 | High molecular weight (C_(35)^+) n-alkanes of Neogene heavily biodegraded oil in the Qianmiqiao region,North China显示文摘With wax content of 1.62%, heavy oil has been produced from the sandstone reservoirs of Neogene Guantao Formation (Ng1m). In the GC and GC-MS RIC profiles of its aliphatic fraction, n-alkanes are totally lost, which shows the result of heavy biodegradedation. However, the remaining trace C13-C36 n-alkanes can be still seen from its mlz 85 mass chromatogram. In addition, a complete series of C35-C73 high molecular weight (HMW) n-alkanes was detected by high-temperature gas chromatography (HTGC). The HMW R-alkane series shows a normal distribution pattern, a major peak at nC43, obvious odd-carbon-number predominance, CPI37-55 and OEP45-49 values up to 1.17 and 1.16-1.20 respectively. The present study not only has conformed the strong resistibility of HMW n-alkanes to biodegradation in crude oils as concluded by previous researchers, but also has provided some significant information on source input and maturity for the heavily biodegraded oil in the Qianmiqiao region. | WANG Tieguan (T.-G. WANG), ZHU Dan, ZHANG Zhihuan, LU Hong & YANG ChiyinKey Laboratory of Petroleum Entrapment Mechanism of the Ministry of Education, University of Petroleum, Beijing 102200, China Guangzhou Institute of Geochemistry, Chinese Academy of S | 2002 | Chinese Science Bulletin2002，47，16： | 8 |
| 13 | p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation显示文摘Pancreatic cancer is one of the most aggressive and lethal malignancies worldwide, with a very poor prognosis and a five-year survival rate less than 8%. This dismal outcome is largely due to delayed diagnosis, early distant dissemination and resistance to conventional chemotherapies. Kras mutation is a well-defined hallmark of pancreatic cancer, with over 95% of cases harbouring Kras mutations that give rise to constitutively active forms of Kras. As important down-stream effectors of Kras, p21-activated kinases(PAKs) are involved in regulating cell proliferation, apoptosis, invasion/migration and chemo-resistance. Immunotherapy is now emerging as a promising treatment modality in the era of personalized anti-cancer therapeutics. In this review, basic knowledge of PAK structure and regulation is briefly summarised and the pivotal role of PAKs in Kras-driven pancreatic cancer is highlighted in terms of tumour biology and chemoresistance. Finally, the involvement of PAKs in immune modulation in the tumour microenvironment is discussed and the potential advantages of targeting PAKs are explored. | Kai Wang Graham S Baldwin Mehrdad Nikfarjam Hong He | 2018 | World Journal of Gastroenterology2018，24，33： | 7 |
| 14 | 用防老剂及并用防老剂提高轮胎胶料的耐屈挠疲劳和动态臭氧龟裂性能显示文摘为了延长轮胎使用寿命 ,轮胎公司一直在试图研究改进轮胎各部件的屈挠疲劳性能和轮胎外部件如胎侧、胎面及三角胶在动态臭氧条件下的耐龟裂性能。本文研究了用各种防老剂及其并用来改进轮胎内部件的屈挠疲劳性能 ,还评价了通过防老剂并用来改进外部件的动态臭氧龟裂性能 ,并进而推荐了适宜的防老剂及防老剂并用。此外 ,本文还根据实验室的试验结果 ,讨论了防老剂如何防止氧化破坏及臭氧如何与防老剂发生反应的假设机理。 | Hong S W Lin C Y | 2002 | 轮胎工业2002，22，3： | 7 |
| 15 | Admission Glucose and In-hospital Mortality after Acute Myocardial Infarction in Patients with or without Diabetes: A Cross-sectional Study显示文摘 | Shi Zhao Karthik Murugiah Na Li Xi Li Zi-Hui Xu Jing Li Chen Cheng Hong Mao Nicholas S Downing Harlan M Krumholz Li-Xin Jiang | 2017 | Chinese Medical Journal2017，，7： | 6 |
| 16 | Genetic characterization and potential molecular dissemination mechanism of tet(31) gene in Aeromonas caviae from an oxytetracycline wastewater treatment system显示文摘Recently, the rarely reported tet(31) tetracycline resistance determinant was commonly found in Aeromonas salmonicida, Gallibacterium anatis, and Oblitimonas alkaliphila isolated from farming animals and related environment. However, its distribution in other bacteria and potential molecular dissemination mechanism in environment are still unknown. The purpose of this study was to investigate the potential mechanism underlying dissemination of tet(31) by analysing the tet(31)-carrying fragments in A. caviae strains isolated from an aerobic biofilm reactor treating oxytetracycline bearing wastewater. Twenty-three A. caviae strains were screened for the tet(31) gene by polymerase chain reaction(PCR). Three strains(two harbouring tet(31), one not) were subjected to whole genome sequencing using the PacBio RSII platform. Seventeen A. caviae strains carried the tet(31) gene and exhibited high resistance levels to oxytetracycline with minimum inhibitory concentrations(MICs)ranging from 256 to 512 mg/L. tet(31) was comprised of the transposon Tn6432 on the chromosome of A. caviae, and Tn6432 was also found in 15 additional tet(31)-positive A. caviae isolates by PCR. More important, Tn6432 was located on an integrative conjugative element(ICE)-like element, which could mediate the dissemination of the tet(31)-carrying transposon Tn6432 between bacteria. Comparative analysis demonstrated that Tn6432 homologs with the structure ISCR2-ΔphzF-tetR(31)-tet(31)-ΔglmM-sul2 were also carried by A. salmonicida, G. anatis, and O. alkaliphila, suggesting that this transposon can be transferred between species and even genera. This work provides the first report on the identification of the tet(31) gene in A. caviae, and will be helpful in exploring the dissemination mechanisms of tet(31) in water environment. | Yanhong Shi Zhe Tian Sébastien Olivier Leclercq Hong Zhang Min Yang Yu Zhang | 2019 | Journal of Environmental Sciences2019，31，2： | 4 |
| 17 | Alternative splicing as a biomarker and potential target for drug discovery显示文摘其他的拼接在 pre-mRNA 成熟期间是 multi-exonic 基因表示的一个关键过程。在这个过程,基因的特别 exons 将被包括在以内或从最后的成熟 mRNA,和产生抄本排除了产生多样的蛋白质 isoforms。最近的证据证明有多重 exons 的约 95% 人的基因经历在 pre-mRNA 成熟期间的其他的拼接。因此,其他的拼接在生理的进程和房间开发程序起一个关键作用,其他的拼接的 and.dysregulation 高度与人的疾病被联系例如癌症,糖尿病和 neurodegenerative 疾病。在这评论,我们讨论其他的拼接的规定,检验在其他的拼接和人的疾病之间的关系,并且描述修改其他的拼接的几条途径,它能帮助人的疾病诊断和治疗。 | Kai-qin LE Bellur S PRABHAKAR Wan-jin HONG Liang-cheng LI | 2015 | Acta Pharmacologica Sinica2015，36，10： | 4 |
| 18 | Color Doppler ultrasonographic examination on the relationship between the gallbladder bed and major branch of the middle hepatic vein显示文摘BACKGROUND: There is a controversy about the risk of injury to the branch of the middle hepatic vein during lapa- roscopic cholecystectomy. This study was conducted to further investigate the relationship between the gallbladder bed and the branch of the middle hepatic vein. METHODS: Color Doppler ultrasound was used to exa- mine the anatomical relationship between the gallbladder bed and the branches of the middle hepatic vein in 143 healthy volunteers. RESULTS: Not all the middle hepatic vein extended close to the gallbladder bed, the branches and gallbladder beds in 23 subjects were not in the same plane during ultrasound scanning. In 21 of the 143 subjects the branch of the middle hepatic vein was completely adherent to the gallbladder bed with a diameter ranging from 1.2 mm to 3.6 mm. In 10 subjects the branches of the middle hepatic vein traversed approximately 1.0 mm from the gallbladder bed with a dia- meter ranging from 1.6 mm to 3.0 mm. CONCLUSIONS: In most subjects the branch of the middle hepatic vein and the gallbladder bed are well separated. Only patients with large branches of the middle hepatic vein close to the gallbladder bed are at risk of hemorrhage during laparoscopic cholecystectomy. | Wei-Zhong Zhang, Jie Shen, Jue-Xing Xie and Hong Zhu Taizhou, China Departments of Surgery and Ultrasonography , Taizhou First People’s Hospital, Taizhou 318020, China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，2： | 3 |
| 19 | The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase显示文摘Suicide genes have recently emerged as an attractive alternative therapy for the treatment of various types of intractable cancers.The efficacy of suicide gene therapy relies on efficient gene delivery to target tissues and the localized concentration of final geneproducts. | Chang DY Yoo SW Hong Y Kim S Kim SJ Yoon SH Cho KG Paek SH Lee YD Kim SS Suh-Kim H | 2010 | 中国神经肿瘤杂志2010，8，2： | 3 |
| 20 | Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation显示文摘 | Liu B Du L Hong J S | 2000 | J Pharmacol Exp Ther2000，293，2： | 2 |
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