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| 1 | A new neuroprotective bakkenolide from the rhizome of Petasites tricholobus显示文摘新 bakkenolide 类型混合物, bakkenolide-Va (1 ) ,从 Petasites tricholobus 的根茎被孤立。结构根据各种各样的 NMR 被描绘(1H, 13C, 1H 鈥 ? H 舒适, HMQC, HMBC 和 NOESY ) 并且集体 spectrometry 数据。bakkenolide-Va 的 neuroprotective 活动在组织缺氧葡萄糖剥夺和氧化侮辱的各种各样的类型对待的首先有教养的神经原被调查。 | Na Zhang Mei Li Guo Ge Zhang Run Ping Li | 2008 | Chinese Chemical Letters2008，19，7： | 7 |
| 2 | Relationship Between Coleoptile Length and Drought Resistance and Their QTL Mapping in Rice显示文摘By using a set of recombinant inbred line(RIL)population involving in 195 lines derived from a cross of Zhenshan 97B (lowland variety)and IRAT109(upland variety),the correlation analysis between coleoptile length(CL)and drought resistance index (DRI)and their QTL identification were conducted.There existed a significantly positive relationship between CL and DRI with the correlation coefficient of 0.2206**under water stress conditions.Under normal and water stress conditions,a total of eleven and four QTLs for CL and DRI,respectively,were detected on chromosomes 1,2,4,5,6,7,9,11 and 12 by using a linkage map including 213 SSR markers,which explained 4.84%to 22.65%of phenotypic variance.Chromosomes 1 and 9 possessing the QTLs for DRI harbored simultaneously QTLs for CL,and qCL9 shared the same chromosome location with qDRI9(RM160-RM215).Comparing the QTLs related to drought resistance in other studies,QTLs for CL and DRI were located in the same or adjacent marker interval as those related to root traits,such as number,dry weight,depth,and length of root.Moreover,sixteen and three pairs of epistatic loci for CL and DRI were found,which accounted for 56.17%and 11.93%of the total variation in CL and DRI,respectively. | HU Song-ping YANG Hua ZOU Gui-hua LIU Hong-yan LIU Guo-lan MEI Han-wei CAI Run LI Ming-shou LUO Li-jun | 2007 | Rice science2007，14，1： | 4 |
| 3 | Burst strain disturbance—A new test study on fracture precursor显示文摘IntroductionBeforeanearthquakeocuurs,deformationvariationsobviouslyappearinseismogenicareaandnearbywhichwerereportedalot.Earl... | ZHAO YONG XU 1) RUN HAI YANG 1) BIN WANG 1) JIN MING ZHAO 1) YU FENG YAO 1) PEI ZHONG HUA 1) SHI RONG MEI 2) 1) Seismological Bureau of Yunnan Province, Kunming, 650041, China 2) Center for Analysi | 1998 | Acta Seismologica Sinica(English Edition)1998，11，6： | 1 |
| 4 | Antifatigue activity of phenylethanoid‐rich extract from Cistanche deserticola显示文摘 | Run‐LanCai Mei‐HuaYang YueShi JunChen Yong‐ChaoLi YunQi | 2010 | Phytother. Res2010，，： | 1 |
| 5 | Rapid deswelling of sodium alginate/poly ( N - isopropylaerylamide) semi - interpenetrating polymer network hydrogels in response to temperature and pH changes 显示文摘 | Zhang Gao - Qi Zhou Mei - Hua Liang Bo - Run | 2005 | Colloid and Polymer Science2005，283，4： | 1 |
| 6 | Antifatigue activity of phenylethanoid-rich extract from Cistanche eserticola显示文摘 | Cai Run Lan Yang Mei Hua Shi Yue | | 0，，02： | 1 |
| 7 | Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury显示文摘Fidgetin,a microtubule-severing enzyme,regulates neurite outgrowth,axonal regeneration,and cell migration by trimming off the labile domain of microtubule polymers.Because maintenance of the microtubule labile domain is essential for axon initiation,elongation,and navigation,it is of interest to determine whether augmenting the microtubule labile domain via depletion of fidgetin serves as a therapeutic approach to promote axonal regrowth in spinal cord injury.In this study,we constructed rat models of spinal cord injury and sciatic nerve injury.Compared with spinal cord injury,we found that expression level of tyrosinated microtubules in the labile portion of microtubules continuously increased,whereas fidgetin decreased after peripheral nerve injury.Depletion of fidgetin enhanced axon regeneration after spinal cord injury,whereas expression level of end binding protein 3(EB3)markedly increased.Next,we performed RNA interference to knockdown EB3 or fidgetin.We found that deletion of EB3 did not change fidgetin expression.Conversely,deletion of fidgetin markedly increased expression of tyrosinated microtubules and EB3.Deletion of fidgetin increased the amount of EB3 at the end of neurites and thereby increased the level of tyrosinated microtubules.Finally,we deleted EB3 and overexpressed fidgetin.We found that fidgetin trimmed tyrosinated tubulins by interacting with EB3.When fidgetin was deleted,the labile portion of microtubules was elongated,and as a result the length of axons and number of axon branches were increased.These findings suggest that fidgetin can be used as a novel therapeutic target to promote axonal regeneration after spinal cord injury.Furthermore,they reveal an innovative mechanism by which fidgetin preferentially severs labile microtubules. | Chao Ma Junpei Wang Qifeng Tu Weijuan Bo Zunlu Hu Run Zhuo Ronghua Wu Zhangji Dong Liang Qiang Yan Liu Mei Liu | 2023 | Neural Regeneration Research2023，18，12： | 0 |
| 8 | A Review and Outlook on Predictive Cruise Control of Vehicles and Typical Applications Under Cloud Control System显示文摘With the application of mobile communication technology in the automotive industry,intelligent connected vehicles equipped with communication and sensing devices have been rapidly promoted.The road and traffic information perceived by intelligent vehicles has important potential application value,especially for improving the energy-saving and safe-driving of vehicles as well as the efficient operation of traffic.Therefore,a type of vehicle control technology called predictive cruise control(PCC)has become a hot research topic.It fully taps the perceived or predicted environmental information to carry out predictive cruise control of vehicles and improves the comprehensive performance of the vehicle-road system.Most existing reviews focus on the economical driving of vehicles,but few scholars have conducted a comprehensive survey of PCC from theory to the status quo.In this paper,the methods and advances of PCC technologies are reviewed comprehensively by investigating the global literature,and typical applications under a cloud control system(CCS)are proposed.Firstly,the methodology of PCC is generally introduced.Then according to typical scenarios,the PCC-related research is deeply surveyed,including freeway and urban traffic scenarios involving traditional vehicles,new energy vehicles,intelligent vehicles,and multi-vehicle platoons.Finally,the general architecture and three typical applications of the cloud control system(CCS)on PCC are briefly introduced,and the prospect and future trends of PCC are proposed. | Bolin Gao Keke Wan Qien Chen Zhou Wang Rui Li Yu Jiang Run Mei Yinghui Luo Keqiang Li | 2023 | Machine Intelligence Research2023，20，5： | 0 |
| 9 | Research on flaky and vertical gas diffusion electrode显示文摘Flaky and vertical gas diffusion electrode was propos, ed to improve the efficiency of fuel cells. The discharge experiments were done to compare the discharge capability of the electrode with different PTFE ingredient and different basal body uniformity. The results showed the electrode with 10% PTFE and high uniformity was favorable to discharge. This single electrode could discharge about 100 h at 150 mA(no noble metal catalyst). The electrode made of the punched screens was superior to that made of the foam Ni. | ZHU Mei XU Xian-zhi SU Run YANG Ji-ming 朱梅 徐献芝 苏润 杨基明 | 2004 | 电池2004，34，3： | 0 |
| 10 | Construction and validation of a severity prediction model for metabolic associated fatty liver disease显示文摘Objective:To analyze the independent risk factors for the occurrence of moderate-to-severe metabolic-associated fatty liver disease(MAFLD),to construct a prediction model for moderate-to-severe MAFLD,and to verify the validity of the model.Methods:In the first part,278 medical examiners who were diagnosed with MAFLD in Medical Examination Center at the Second Affiliated Hospital of Hainan University from January to May 2022 were taken as the study subjects(training set),and they were divided into mild MAFLD group(200)and moderate-severe MAFLD group(78)based on ultrasound results.Demographic data and laboratory indexes were collected,and risk factors were screened by univariate and multifactor analysis.In the second part,a dichotomous logistic regression equation was used to construct a prediction model for moderate-to-severe MAFLD,and the model was visualized in a line graph.In the third part,the MAFLD population(200 people in the external validation set)from our physical examination center from November to December 2022 was collected as the moderate-to-severe MAFLD prediction model,and the risk factors in both groups were compared.The receiver operating characteristic(ROC)curves,calibration curves,and clinical applicability of the model were plotted to represent model discrimination for internal and external validation.Results:The risk factors of moderate-to-severe MAFLD were fasting glucose(FPG),blood uric acid(UA),triglycerides(TG),triglyceride glucose index(TyG),total cholesterol(CHOL),and high-density lipoprotein(HDL-C).UA[OR=1.021,95%CI(1.015,1.027),P<0.001]and FPG[OR=1.575,95%CI(1.158,2.143),P=0.004]were independent risk factors for people with moderate to severe MAFLD.The visualized line graph model showed that UA was the factor contributing more to the risk of moderate to severe MAFLD in this model.The ROC curves showed AUC values of 0.8701,0.8686 and 0.7991 for the training set,internal validation set and external validation set,respectively.The curves almost coincided with the reference line after calibration of the model calibration degree with P>0.05 in Hosmer-Lemeshow test.The decision curve analysis(DCA)plotted by the clinical applicability of the model was higher than the two extreme curves,predicting that patients with moderate to severe MAFLD would benefit from the prediction model.Conclusion:The prediction model constructed by combining FPG with UA has higher accuracy and better clinical applicability,and can be used for clinical diagnosis. | ZHANG Da‑ya CHEN Shi‑ju CHEN Run‑xiang ZHANG Xiao‑dong HUANG Shi‑mei ZENG Fan CHEN Chen LI Da BAI Fei‑hu | 2023 | Journal of Hainan Medical University2023，29，8： | 0 |
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