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29篇 您的检索式：作者名="Ruizhan"

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	题名	作者	年代	出处	被引量
1	METTL3-mediated m^(6)A RNA methylation regulates dorsal lingual epithelium homeostasis显示文摘The dorsal lingual epithelium,which is composed of taste buds and keratinocytes differentiated from K14^(+)basal cells,discriminates taste compounds and maintains the epithelial barrier.N6-methyladenosine(m^(6)A)is the most abundant mRNA modification in eukaryotic cells.How METTL3-mediated m^(6)A modification regulates K14^(+)basal cell fate during dorsal lingual epithelium formation and regeneration remains unclear.Here we show knockout of Mettl3 in K14^(+)cells reduced the taste buds and enhanced keratinocytes.Deletion of Mettl3 led to increased basal cell proliferation and decreased cell division in taste buds.Conditional Mettl3 knock-in mice showed little impact on taste buds or keratinization,but displayed increased proliferation of cells around taste buds in a protective manner during post-irradiation recovery.Mechanically,we revealed that the most frequent m^(6)A modifications were enriched in Hippo and Wnt signaling,and specific peaks were observed near the stop codons of Lats1 and FZD7.Our study elucidates that METTL3 is essential for taste bud formation and could promote the quantity recovery of taste bud after radiation.	Qiuchan Xiong Caojie Liu Xin Zheng Xinyi Zhou Kexin Lei Xiaohan Zhang Qian Wang Weimin Lin Ruizhan Tong Ruoshi Xu Quan Yuan	2022	International Journal of Oral Science2022，14，3：	2
2	Experiment study on ultrahigh pressure extraction of Ginsenosides显示文摘	Zhang Shouqin Chen Ruizhan Wang Changzheng	2007	Journal of Food Engineering2007，，79：	1
3	Effeets of ultrahigh pressure extraction conditions on yields and antioxidant activity of ginsertoside from ginseng显示文摘	Ruizhan Chen Fanlei Meng Shouqin Zhang	2009	Separation and Purification Technology2009，66，2：	1
4	Optimization of ultrasonic extraction process of polysaccharides from Ornithogalum caudatum Ait and evaluation of its biological activities显示文摘	CHEN Ruizhan LI Yuan DONG Hang	2012	Ultrasonics Sonochemistry2012，，19：	1
5	Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait显示文摘	Ruizhan Chen Fanlei Meng Zhiqiang Liu Ruiping Chen Min Zhang	2010	Carbohydrate Polymers2010，，3：	1
6	Antitumor activity of different fractions of polysaccharide purified from Ornithoga!um caudatum A it显示文摘	Ruizhan Chen Fanlei Meng Zhiqiang Liu	2010	Carbohydrate Polymers2010，80，：	1
7	Antioxidant and immunobiological activity of water-soluble polysaecha- ride fractions purified from Acanthopanax senticosu 显示文摘	Chen Ruizhan Liu Zhiqiang Zhao Jimin	2011	Food Chemistry2011，127，2：	1
8	Optimization of ultrasonic extraction process of polysaccharides from Ornithogalum Caudatum Ait and evaluation of its biological activities显示文摘	Ruizhan Chen Yuan Li Hang Dong Zhiqiang Liu Shizhe Li Simin Yang Xinlong Li	2012	Ultrasonics - Sonochemistry2012，，6：	1
9	Antioxidant and imrnunobiologial activity of water-soluble polysacehafide fraction puri- fied from Acanthopanax senficosu显示文摘	CHEN Ruizhan LIU Zhiqiang ZHAO Jimin	2011	Food Chemistry2011，127，：	1
10	Effects of ultrahigh pressure extraction conditions on yields and antioxidant activity of ginsenoside from ginseng显示文摘	Ruizhan Chen Fanlei Meng Shouqin Zhang et ol	2009	Separation and Purification Technology2009，66，2：	1
11	Antioxidant and immunobiological activity of water - soluble polysaccharide frac- tions purified from Acanthopanax senticosu 显示文摘	Ruizhan Chen Zhiqiang Liu Jimin Zhao	2011	Food Chemistry2011，127，2：	1
12	Thrust reverser optimization for safety with CFD显示文摘	QIAN Ruizhan ZHU Ziqiang DUAN Zhuoyi	2011	Procedia Engineering2011，17，：	1
13	Optimization extraction, characterization and antioxidant activities of pectic polysaccharide from tangerine peels 显示文摘	Ruizhan Chen Chenguang Jin Zhigang Tong	2016	Carbohydrate Polymers2016，，136：	1
14	Antioxidant and immunobiologieal activity of water-soluble polysaccharide fractions purified from Acanthopanax senticosu 显示文摘	Chen Ruizhan Liu Zhiqiang Zhao Jimin	2011	Food Chemistry2011，，127：	1
15	显示文摘	Wang Xiaoju Chen Ruizhan Qu Yahuan	2000	J Rare Earths2000，18，2：	1
16	显示文摘	Qu Yahuan Wang Xiaoju Chen Ruizhan	2001	J Rare Earths2001，19，2：	1
17	Ginsenoside extraction from Panax quinquefolium I- (American ginseng) root by using ultrahigh pressure 显示文摘	Zhang Shouqin Chen Ruizhan Wu Hua	2006	J Pharmaceut Biomed2006，，41：	1
18	Antitumor activities of different fractions of polysaccharide purified from Ornithogalum caudatum Ait显示文摘	Chen Ruizhan Meng Fanlei Liu Zhiqiang	2010	Carbohydrate Polymers2010，80，3：	1
19	Antitumor activi- ties of different fractions of polysaccharide purified from Oruithog- alum caudatum Ait 显示文摘	Chen Ruizhan Meng Fanlei Liu Zhiqiang	2010	Carbohydrate Polymers2010，80，3：	1
20	Antioxidant and immunobiological activity of water-soluble polysaccharide fractions purified from Acanthopanax senticosu显示文摘	Ruizhan Chen Zhiqiang Liu Jimin Zhao	2011	Food Chemistry2011，127，：	1

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