|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Circular smooth muscle contributes to esophageal shortening during peristalsis显示文摘AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis,the angles between the LSM and CSM layers were measured in 9 cadavers.The outer longitudinal layer of the muscularis propria was exposed after stripping the outer serosa.The inner circular layer of the muscularis propria was then revealed after dissection of the esophageal mucosa and the underlying muscularis mucosa.Photographs of each specimen were taken with half of the open esophagus folded back showing both the outer longitudinal and inner circular muscle layers.Angles were measured every one cm for 10 cm proximal to the squamocolumnar junction(SCJ) by two independent investigators.Two human esophagi were obtained from organ transplant donors and the angles between the circular and longitudinal smooth muscle layers were measured using micro-computed tomography(micro CT) and Image J software.RESULTS:All data are presented as mean ± SE.The CSM to LSM angle at the SCJ and 1 cm proximal to SCJ on the autopsy specimens was 69.3 ± 4.62 degrees vs 74.9 ± 3.09 degrees,P = 0.32.The CSM to LSM angle at SCJ were statistically significantly lower than at 2,3,4 and 5 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 82.58 ± 1.34 degrees,84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.013,P = 0.008,P = 0.004,P = 0.009 respectively.The CSM to LSM angle at SCJ was also statistically significantly lower than the angles at 6,7 and 8 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 80.18 ± 2.09 degrees,81.81 ± 1.75 degrees and 80.96 ± 2.04 degrees,P = 0.05,P = 0.02,P = 0.03 respectively.The CSM to LSM angle at 1 cm proximal to SCJ was statistically significantly lower than at 3,4 and 5 cm proximal to the SCJ,74.94 ± 3.09 degrees vs 84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.019,P = 0.008,P = 0.02 respectively.At 10 cm above SCJ the angle was 80.06 ± 2.13 degrees which is close to being perpendicular but less than 90 degrees.The CSM to LSM angles measured on virtual dissection of the esophagus and the stomach on micro CT at the SCJ and 1 cm proximal to the SCJ were 48.39 ± 0.72 degrees and 50.81 ± 1.59 degrees.Rather than the angle of the CSM and LSM being perpendicular in the esophagus we found an acute angulation between these two muscle groups throughout the lower 10 cm of the esophagus.CONCLUSION:The oblique angulation of the CSM may contribute to the significantly greater shortening of distal esophagus when compared to the mid and proximal esophagus during peristalsis. | Anil K Vegesna Keng-Yu Chuang Ramashesai Besetty Steven J Phillips Alan S Braverman Mary F Barbe Michael R Ruggieri Larry S Miller | 2012 | World Journal of Gastroenterology2012，18，32： | 7 |
| 2 | Vascular endo-thelial growth factor (VEGF) as a target of bevacizum-ab in cancer: from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | CurrMed Chem2006，13，16： | 1 |
| 3 | Vascular endothelial growth factor(VEGF) as a target of bevacizumab in cancer:from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Med Chem2006，13，16： | 1 |
| 4 | CardioVascular adaptation during action pistol shooting 显示文摘 | Fenici R Ruggieri M P Brisinda D | 1999 | Sports Med Phys Fitness1999，39，3： | 1 |
| 5 | Clinical and electroencephalographic aspects of late infantile neuronal ceroid lipofuscinosis显示文摘 | Caraballo R Sologuestua A Ruggieri VL | 2005 | Rev Neurol2005，40，3： | 1 |
| 6 | Vascular endothelial growth factor ( VEGF ) as a target of bevacizumab in cancer: from the biology to the clinic显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Medchem2006，13，16： | 1 |
| 7 | Mechanisms in prostatitis/chronic pelvic pain syndrome显示文摘 | Pontari M A Ruggieri M R | 2008 | J Urol2008，179，5： | 1 |
| 8 | Numerical modeling of ductile crack growth in 3-D using computational cell elements 显示文摘 | RUGGIERI C PANONTIN T L DODDS JR R H | 1990 | International Journal of Fracture1990，82，1： | 1 |
| 9 | Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Med Chem2006，13，16： | 1 |
| 10 | PET manifestation in different types of pathology in epilepsy显示文摘 | Talanow R Ruggieri P Alexopoulos A | 2009 | Clin Nucl Med2009，34，10： | 1 |
| 11 | Glutamate-mediated astrocyte-to-neuron signalling in the rat dorsal hom显示文摘 | Bardoni R Ghirri A Zonta M Betelli C Vitale G Ruggieri V Sandrini M Carmignot | | 0，，： | 1 |
| 12 | A search for evidence of somatic mutations in the NF1 gene显示文摘 | John AM Ruggieri M Femer R | 2000 | J Med Genet2000，37，1： | 1 |
| 13 | Vascular endothelial growth factor(VEGF)as a target of bevacizumab in cancer:from the biology to the clinic显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Med Chem2006，13，16： | 1 |
| 14 | Calibration of weibull stress model using fracture toughness data 显示文摘 | Gao X Ruggieri C Dodds R H | 1998 | International Journal of Fracture1998，92，2： | 1 |
| 15 | MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae 显示文摘 | Ruggieri R Tanaka K Nakafuku M | 1989 | Cell Bi- ology1989，86，： | 1 |
| 16 | Mechanisms in prostatitis/chronic pelvic pain syndrome显示文摘 | Pontari M A Ruggieri M R | 2004 | J Urol2004，172，3： | 1 |
| 17 | Antigenic and sequence analysis of H3 influenza virus haemagglutinins from pigs in Italy 显示文摘 | Castrucci M R Campitelli L Ruggieri A | 1994 | J Gen Virol1994，75，： | 1 |
| 18 | Low Temperature Growth of Nanocrystalline Fe2TiO5 Perovskite Thin Films by Sol-gel Process Assisted by Microwave Irradiation 显示文摘 | Phani A R Ruggieri F Passacantando M | 2008 | Ceramics International2008，34，： | 1 |
| 19 | Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer:from the biology to the clinic显示文摘 | Ranieri G Patruno R Ruggieri E | | 0，，16： | 1 |
| 20 | Serum N-acetylaspartate level in amyotrophic lateral sclerosis显示文摘 | Simone I L Ruggieri M Tortelli R | 2011 | Arch Neurol2011，68，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员