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| 1 | Performance of liver stiffness measurements by transient elastography in chronic hepatitis显示文摘AIM:To compare results of liver stiffness measurements by transient elastography(TE) obtained in our patients population with that used in a recently published meta-analysis.METHODS:This was a single center cross-sectional study.Consecutive patients with chronic viral hepatitis scheduled for liver biopsy at the outpatient ward of our Infectious Diseases Department were enrolled.TE was carried out by using FibroScan(Echosens,Paris,France).Liver biopsy was performed on the same day as TE,as day case procedure.Fibrosis was staged according to the Metavir scoring system.The diagnostic performance of TE was assessed by using receiver operating characteristic(ROC) curves and the area under the ROC curve analysis.RESULTS:Two hundred and fifty-two patients met the inclusion criteria.Six(2%) patients were excluded due to unreliable TE measurements.Thus,246(171 men and 75 women) patients were analyzed.One hundred and ninety-five(79.3%) patients had chronic hepatitis C,41(16.7%) had chronic hepatitis B,and 10(4.0%) were coinfected with human immunodeficiency virus.ROC curve analysis identified optimal cut-off value of TE as high as 6.9 kPa forF ≥ 2;7.9 kPa forF ≥ 3;9.6 kPa for F = 4 in all patients(n = 246),and as high as 6.9 kPa for F ≥ 2;7.3 kPa for F ≥ 3;9.3 kPa for F = 4 in patients with hepatitis C(n = 195).Cut-off values of TE obtained by maximizing only the specificity were as high as 6.9 kPa for F ≥ 2;9.6 kPa for F ≥ 3;12.2 kPa for F = 4 in all patients(n = 246),and as high as 7.0 kPa forF ≥ 2;9.3 kPa forF ≥ 3;12.3 kPa forF = 4 in patients with hepatitis C(n = 195).CONCLUSION:The cut-off values of TE obtained in this single center study are comparable to that obtained in a recently published meta-analysis that included up to 40 studies. | Giovanna Ferraioli Carmine Tinelli Barbara Dal Bello Mabel Zicchetti Raffaella Lissandrin Gaetano Filice Carlo Filice Elisabetta Above Giorgio Barbarini Enrico Brunetti Willy Calderon Marta Di Gregorio Roberto Gulminetti Paolo Lanzarini Serena Ludovisi Laura Maiocchi Antonello Malfitano Giuseppe Michelone Lorenzo Minoli Mario Mondelli Stefano Novati Savino FA Patruno Alessandro Perretti Gianluigi Poma Paolo Sacchi Domenico Zanaboni Marco Zaramella | 2013 | World Journal of Gastroenterology2013,19,1: | 18 |
| 2 | Nonalcoholic fatty liver disease, spleen and psoriasis:New aspects of low-grade chronic inflammation显示文摘AIM: To investigate spleen status in psoriasis and itsrelationship with hepatic steatosis, Psoriasis Area and Severity Index, and insulin resistance.METHODS: Seventy-nine psoriatic patients who were not suffering from any chronic inflammatory disease were retrospectively selected for inclusion in this study,and their complete medical records were accessed.An age- and sex-matched group of 80 non-psoriatic,obese patients was included as a control. The following relevant data were collected: age, sex, weight, height,body mass index, waist circumference, blood pressure,insulin resistance status, age at psoriasis onset, and severity of psoriasis. Abdominal ultrasonography was performed to determine spleen longitudinal diameter(SLD), and hepatic steatosis grade.RESULTS: The SLD of control obese patients was greater than that of psoriatic subjects(P = 0.013),but body mass index predicted the size of the spleen in psoriatic patients(P < 0.001). The SLD of psoriatic patients with normal weight was significantly reduced with respect to the overweight/obese psoriatic patients(P = 0.002). A multiple regression analysis revealed that body mass index was a unique predictor of the spleen size(P < 0.001). Finally, the disease duration predicted the spleen size in psoriatic subjects(P =0.038).CONCLUSION: This study shows a correlation between the SLD and the duration of psoriasis. | Nicola Balato Maddalena Napolitano Fabio Ayala Cataldo Patruno Matteo Megna Giovanni Tarantino | 2015 | World Journal of Gastroenterology2015,21,22: | 3 |
| 3 | Vascular endo-thelial growth factor (VEGF) as a target of bevacizum-ab in cancer: from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | CurrMed Chem2006,13,16: | 1 |
| 4 | Vascular endothelial growth factor concentrations in the plasma-activated platelets rich (P-APR) of healthy controls and colorectal cancer patients显示文摘 | Ranieri G Coviello M Patruno R | 2004 | Oncol Rep2004,12,4: | 1 |
| 5 | VEGF concentration from plasma activated platelets rich correlates with microvascular density and grading in canine mast cell tumor spontaneous model 显示文摘 | Patruno R Arpaia N Gadaleta CD | 2008 | J Cell Mol Med2008,13,3: | 1 |
| 6 | Vascular endothelial growth factor(VEGF) as a target of bevacizumab in cancer:from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Med Chem2006,13,16: | 1 |
| 7 | The transient syndrome of headache with neurological deficits,cerebrospinal fluid pleocytosis and acute confusional state:a case report显示文摘 | Giorgetti A Mariani G Patruno GM | | 0,,: | 1 |
| 8 | Myostatin shows a specific expression pattern in pig skeletal and ex- traocular muscles during pre-and post-natal growth显示文摘 | Patruno M Caliaro F Maccatrozzo L | 2008 | Differentiation2008,76,2: | 1 |
| 9 | Canine adipose-derived-mesenchymal stem cells do not lose stem features after a long-term cryopreservation显示文摘 | T. Martinello I. Bronzini L. Maccatrozzo A. Mollo M. Sampaolesi F. Mascarello M. Decaminada M. Patruno | 2010 | Research in Veterinary Science2010,,1: | 1 |
| 10 | Vascular endothelial growth factor ( VEGF ) as a target of bevacizumab in cancer: from the biology to the clinic显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Medchem2006,13,16: | 1 |
| 11 | Kinetic study on the effects of extremely low frequency electromagnetic field on catalase,cy-tochrome P450 and inducible nitric oxide synthase in human HaCaT and THP-1 cell lines显示文摘 | Patruno A Tabrez S Amerio P | 2011 | CNS Neurol Disord Drug Targets2011,10,8: | 1 |
| 12 | Extremely low frequency electromagnetic field and wound healing: implication of cytokines as biological mediators 显示文摘 | PESCE M PATRUNO A SPERANZA L | 2013 | European Cytokine Network2013,24,1: | 1 |
| 13 | Tlyptase- positive mast cells correlate with angiogenesis in early breast cancer patients显示文摘 | Ranieri G Ammendola M Patruno R | 2009 | Int J Oncol2009,35,1: | 1 |
| 14 | Breast cancer tissuetryptase expression as a new possible antiangiogenic target显示文摘 | Ammendola M Misino A Patruno R | 2011 | Breast2011,20,1: | 1 |
| 15 | Adverse skin reactions to vitamin K1 : report of 2 cases 显示文摘 | Balato N Cuccuruiio FM Patruno C Ayaia F | 1998 | Contact Dermatitis1998,38,6: | 1 |
| 16 | Fiber types in canine muscles:myosin isoform expression and functional characterization显示文摘 | TONIOLO L MACCATROZZO L PATRUNO M | | 0,,05: | 1 |
| 17 | Mast Cells Density Positive to Tryptase Correlates with Angiogenesis in Pancreatic Ductal Adenocarcinoma Patients Having Undergone Surgery显示文摘 | Michele Ammendola Rosario Sacco Giuseppe Sammarco Giuseppe Donato Valeria Zuccalà Maria Luposella Rosa Patruno Ilaria Marech Severino Montemurro Nicola Zizzo Cosmo Damiano Gadaleta Girolamo Ranieri Niccola Funel | 2014 | Gastroenterology Research and Practice2014,,: | 1 |
| 18 | Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic 显示文摘 | Ranieri G Patruno R Ruggieri E | 2006 | Curr Med Chem2006,13,16: | 1 |
| 19 | Masitinib (AB1010), from canine tumor model to human clinical development: Where we are?显示文摘 | Ilaria Marech Rosa Patruno Nicola Zizzo Claudia Gadaleta Marcello Introna Alfredo Francesco Zito Cosmo Damiano Gadaleta Girolamo Ranieri | 2013 | Critical Reviews in Oncology / Hematology2013,,: | 1 |
| 20 | Localization of IGF-I, IGF-I receptor, and IGFBP-2 in developing Umbrina cirrosa (Pisces: Osteichthyes)显示文摘 | G. Radaelli C. Domeneghini S. Arrighi G. Bosi M. Patruno B. Funkenstein | 2003 | General and Comparative Endocrinology2003,,3: | 1 |