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| 1 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 2 | Cerebral glucose metabolism in acute and persistent vegetative state显示文摘 | GHAEMI M HAUPT WF | 1999 | J Neurosurg Anesthesiol1999，11，1： | 1 |
| 3 | Cleavage ofZearalenone by Trichosporon mycotoxinivorans to a novelnonestrogenic metabolite 显示文摘 | Elisavet V Christian H Rudolf M | 2010 | Applied and EnvironmentalMicrobiology2010，76，7： | 1 |
| 4 | Basal gang haematomas in noncomatose patients:subacute stereotactic aspiration improves longterm outcome in comparison to purely medical teatment 显示文摘 | Gerhard M Robert W Rudolf WC | 2005 | Neurosurg Rev2005，28，： | 1 |
| 5 | A Linear Model for Tracking Error Minimization 显示文摘 | RUDOLF M WOLTER H J ZIMMERMANN H | 1999 | Journal of Banking & Finance1999，23，1： | 1 |
| 6 | Short‐term versus long‐term induction therapy with antithymocyte globulin in orthotopic liver transplantation显示文摘 | Thomas Soliman Hubert Hetz Christoph Burghuber Georg Gy?ri Gerd Silberhumer Rudolf Steininger Ferdinand Mühlbacher Gabriela A. Berlakovich | 2007 | Transplant International2007，，5： | 1 |
| 7 | A linear model for tracking error minimization 显示文摘 | RUDOLF M WOLTER H J ZIMMERMANN H | 1999 | Journal of Banking and Finance1999，23，1： | 1 |
| 8 | Current and future therapies for agerelated macular degeneration显示文摘 | Beutel J Rudolf M Grisanti S | 2009 | Expert Opin Emerg Drugs2009，14，： | 1 |
| 9 | A Linear Model for Tracking Error Minimization显示文摘 | Wolter H J Zimmernann H | 1999 | Journal of Banking & Finance1999，23，1： | 1 |
| 10 | Selenium activates p53 and p38 pathways and induces caspase-independeut cell death in cervical cancer cells显示文摘 | Rudolf E Rudolf K Cervinka M | 2008 | Cell Biol Toxicol2008，24，2： | 1 |
| 11 | Evaluation of luciferase reporter bacteriophage A511:luxAB for detection of Listeria monocytogenes in contaminated foods显示文摘 | Loessner M J Rudolf M Scherer S | 1997 | Appl Environ Microbiol1997，63，： | 1 |
| 12 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruce显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme and Microbial Technology2005，37，2： | 1 |
| 13 | Selenium activates p53 and p38 pathways and induces caspase- independent cell death in cervical cancer cells 显示文摘 | RUDOLF E RUDOLF K CERVINKA M | 2008 | Cell Biol Toxicol2008，24，2： | 1 |
| 14 | Successful sphincter-saving treatment of anorectal malignant melanoma with electrochemotherapy,local excision and adjuvant brachytherapy显示文摘 | Snoj M Rudolf Z Cemazar M | | 0，，03： | 1 |
| 15 | Relationship between microstrueture, eytotoxicity and corrosion properties of a Cu-AI-Ni shape memon'y alloy 显示文摘 | Colic M Rudolf R Stamenkovi6 D | 2010 | Aeta Binmaterialia2010，6，1： | 1 |
| 16 | In vivo monitoring of Ca2+ uptake into mitochondria of mouse skeletal muscle during contraction显示文摘 | Rudolf R Mongillo M Magalhaes P J Pozzan T | 2004 | Cell Biol2004，166，4： | 1 |
| 17 | Efficacy of a commercial inactivated H5 influenza vaccine against highly pathogemc avian influenza H5N1 in waterfowl evaluated under field conditions 显示文摘 | Rudolf M Poppel M Frohlich A | 2009 | Rev Sci Tech2009，28，1： | 1 |
| 18 | Histidine–tryptophan–ketoglutarate solution for organ preservation in human liver transplantation—a prospective multi-centre observation study显示文摘 | Herwig Pokorny Susanne Rasoul-Rockenschaub Felix Langer Thomas Windhager Andreas Rosenstingl Reinhard Lange Alfred K?nigsrainer Burckhardt Ringe Ferdinand Mühlbacher Rudolf Steininger | 2004 | Transplant International2004，，5： | 1 |
| 19 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruce显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme and Microbial Technology2005，37，2： | 1 |
| 20 | A comparison between batch and fed-batch simultaneous saccharification and fermentation of steam pretreated spruee显示文摘 | Rudolf A Alkasrawi M Zacchi G | 2005 | Enzyme Mierob Technoi2005，37，： | 1 |
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