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| 1 | Adult-to-adult right lobe living donor liver transplantation:Comparison of endoscopic retrograde cholangiography with standard T2-weighted magnetic resonance cholangiography for evaluation of donor biliary anatomy显示文摘AIM: To compare the value of endoscopic retrograde cholangiography (ERC) and standard T2-weighted magnetic resonance cholangiography (MRC) in the evaluation process as adult-to-adult right lobe living donor liver transplantation (LDLTx) demands a successful outcome, and exact knowledge of the biliary tree is implicated to avoid biliary complications, postoperatively.METHODS: After starting the LDLTx program, 18 liver transplant candidates were selected for LDLTx by a stepwise evaluation process. ERC and standard T2-weighted MRC were performed to evaluate the biliary system of the donor liver. The anatomical findings of ERC and MRC mapping were compared using the Ohkubo classification. RESULTS: ERC allowed mapping of the whole biliary system in 15/15 (100%) cases, including 14/15 (93.3%) with biliary variants while routine MRC was only accurate in 2/13 (15.4%) cases. MRC was limited in depicting the biliary system proximal of the hepatic bifurcation. Postoperative biliary complications occurred in 2 donors and 8 recipients. Biliary complications were associated with Ohkubo type C, E or G in 6/8 recipients, and 2/3 recipients with biliary leak received a graft with multiple (≥2) bile ducts. CONCLUSION: Pretransplant ERC is safe and superior over standard MRC for detection of biliary variations that occur with a high frequency. However, precise knowledge of biliary variants did not reduce the incidence of postoperative biliary complications. | Perdita Wietzke-Braun Felix Braun Dieter Müller Thomas Lorf Burckhardt Ringe Giuliano Ramadori | 2006 | World Journal of Gastroenterology2006，12，36： | 5 |
| 2 | Initial steroid-free immunosuppression after liver transplantation in recipients with hepatitis c virus related cirrhosis显示文摘AIM: Steroids can increase hepatitis C virus (HCV) replication. After liver transplantation (LTx), steroids are commonly used for immunosuppression and acute rejection is usually treated by high steroid dosages. Steroids can worsen the outcome of recurrent HCV infection. Therefore,we evaluated the outcome of HCV infected liver recipients receiving initial steroid-free immunosuppression.METHODS: Thirty patients undergoing LTx received initial steroid-free immunosuppression. Indication for LTx included 7 patients with HCV related drrhosis. Initial immunosuppression consisted of tacrolimus 2x0.05 mg/kg.d po and mycophenolate mofetil (MMF) 2x15 mg/kg.d po. The tacrolimus dosage wasa djusted to trough levels in the target range of 10-15 μg/Ldudng the first 3 mo and 5-10 μg/L thereafter. Manifestations of acute rejection were verified histologically.RESULTS: Patient and graft survival of 30 patients receiving initial steroid-free immunosuppression was 86% and 83% at 1 and 2 years. Acute rejection occurred in 8/30 patients,including 1 HCV infected recipient. All HCV-infected patients had HCV genotype II (lb). HCV seropositivity occurred within the first 4 mo after LTx. The virus load was not remarkably increased during the first year after LTx. Histologically, grafts had no severe recurrent hepatitis.CONCLUSION: From our experience, initial steroid-free immunosuppression does not increase the risk of acute rejection in HCV infected liver recipients. Furthermore, none of the HCV infected patients developed serious chronic liver diseases. It suggests that it may be beneficial to avoid steroids in this particular group of patients after LTx. | Perdita Wietzke-Braun Felix Braun Burckhart Sattler Giuliano Ramadori Burckhardt Ringe | 2004 | World Journal of Gastroenterology2004，10，15： | 5 |
| 3 | 纤维肌痛综合征的治疗显示文摘背景:目前尚未明确纤维肌痛综合征(fibromyalgia syndrome,FMS)的最佳疗法,相关的综合性循证指导原则也未见报道。
目的:为FMS的最佳治疗提供最新的循证指导原则。
资料来源、选择与提取:检索Cochrane Collaboration Reviews(1993年至2004年)、MEDLINE(1966年至2004年)、CINAHL(1982年至2004年)、EMBASE(1988年至2004年)、PubMed(1966年至2004年)、Heahhstar(1975年至2000年)、Current Contents(2000年至2004年)、Web of Science(1980年至2004年)、Psychlnfo(1887年至2004年)和Sciece Citation Indexes(1996年至2004年)上有关FMS的所有人群试验(随机对照试验及其汇总分析)。由美国疼痛协会(American Pain Society,APS)挑选出13位不同领域的疼痛治疗专家组成多学科小组,负责对文献进行评审。由APS的工作人员和犹他药品信息服务机构(Utah Drug Information Service)对部分文献进行评审,作为补充。共对505篇文章进行了审核。
数据综合:有关FMS的文献存在着重大缺陷,许多治疗性试验观测时间比较短,而且未经过盲法处理。目前,还没有哪种疗法被美国食品与药物管理局(US Food and Drug Administration)特批用于治疗FMS。但是,目前的证据表明,服用小剂量三环类抗抑郁药、开展心血管适应性锻炼、实施认知行为疗法、对患者进行教育都是有效的。其他几种常用疗法(如触发点注射)尚未经充分评价。
结论:尽管FMS是一种复杂的慢性疾病,但现有的药物干预及非药物干预仍能取得临床疗效。依据目前的证据,我们建议逐一实施患者教育、特定药物治疗、锻炼及认知疗法,必要时四管齐下。 | Don L.Goldenberg,MD Carol Burckhardt, PhD Leslie Crofford, MD 孙晓江(译) 戴魁戎(校) | 2005 | 美国医学会杂志(中文版)2005，24，6： | 2 |
| 4 | Surgical treatment of hepatocellular carcinoma: Experience with liver resection and transplantation in 198 patients显示文摘 | Burckhardt Ringe M.D. Rudolf Pichlmayr M.D. Christian Wittekind M.D. Günter Tusch M.S | 1991 | World Journal of Surgery1991，，2： | 2 |
| 5 | Benign Liver Tumors: Differential Diagnosis and Indications for Surgery显示文摘 | Arved Weimann Burckhardt Ringe Jürgen Klempnauer Peter Lamesch Klaus F. Gratz Mathias Prokop Hansj?rg Maschek Günter Tusch Rudolf Pichlmayr | 1997 | World Journal of Surgery1997，，9： | 2 |
| 6 | 澳大利亚木虱在中国发生(英文)显示文摘Blastopsylla occidentalis Taylor是原产于澳大利亚的木虱种类,目前已经扩散到北美、南美、非洲、欧洲和亚洲。本文记述了B.occidentalis在中国的发生,并首次记录了其在澳大利亚以外的地区被寄生。这个种依赖于桉属Eucalyptus植物,其寄主超过20种,这可能是使其在世界范围扩散的一个重要因素。指出了B.occidentalis与桉树芽木虱Blastopsylla barbara Li为同种异名。 | YEN AlanL BURCKHARDT Daniel 岑伊静 | 2013 | 动物分类学报2013，38，2： | 2 |
| 7 | Structure of renal organic anion and cation transporters 显示文摘 | Burckhardt G Wolff N A | 2000 | Am J Physiol Renal Physiol2000，278，6： | 1 |
| 8 | Three monfhly intravenous injection of ibandonat in the treatment of postmenopausal osteoporosis显示文摘 | Thiebaud D Burckhardt P Kriegbaum H | 1997 | American J MED1997，103，： | 1 |
| 9 | Effects of percutaneous coronary interventions in silent ischemia after myocardial infarction: the SWISSI II randomized controlled trial显示文摘 | Erne P Schoenenberger AW Burckhardt D | 2007 | JAMA2007，297，： | 1 |
| 10 | Higher frequency of chro-mosomal aberrations in ovarian endometriosis compared to extrago-nadal endometriosis : a possible link to endometrioid adenocarcinoma显示文摘 | Korner M Burckhardt E Mazzucchelli L | 2006 | Mod Pathol2006，19，12： | 1 |
| 11 | Investigations on thermally forced hydrolysis and phase formation in aqueous iron ( Ⅲ ) nitrate solutions显示文摘 | Schultz M Burckhardt W Barth S T | 1999 | J Mater Sci1999，34，： | 1 |
| 12 | Intravenous zoledronic acid in postmenopausal women with low bone mineral density显示文摘 | Reid IR Brown JP Burckhardt P | 2002 | N Engl J Med2002，346，9： | 1 |
| 13 | The relative lymphocyte count on hospital admission is a risk factor for long-term mortality in patients with acute heart failure显示文摘 | Rudiger A Burckhardt OA Harpes P | | 0，，： | 1 |
| 14 | The challenge: fracture treatment in osteoporotic bone 显示文摘 | Schneider E Goldhahn J Burckhardt P | 2005 | Osteoporos Int2005，16，： | 1 |
| 15 | The fibromyalgia impact questionnaire: development and validation显示文摘 | BURCKHARDT CS CLARK SR BENNETT RM | 1991 | J Rheumatol1991，18，5： | 1 |
| 16 | Effects of chronic widespread pain on the health status and quality of life of women after breast cancer surgery显示文摘 | Burckhardt CS Jones KD | 2005 | Health Qua1 Life Outcomes2005，3，： | 1 |
| 17 | Speckle in ultrasound B-mode scans显示文摘 | BURCKHARDT C B | 1978 | IEEE Trans Sonics Ultrason1978，25，1： | 1 |
| 18 | Uptake of chemically reactive,DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters显示文摘 | Bakhiya N Stephani M Bahn A Ugele B Seidel A Burckhardt G | 2006 | J Am Soc Nephrol2006，17，5： | 1 |
| 19 | Cytocentering:A novel technique enabling automated cell-by-cell patch clamping with the cytopatch chip显示文摘 | Stett A Burckhardt C Weber U | 2003 | Receptors Channels A2003，9，1： | 1 |
| 20 | Pharmacokinetie stud- ies with ehlorthalidone (Hygroton) in man显示文摘 | Riess W Dubach UC Burckhardt D | 1977 | Eur J Clin Phar- macol1977，12，5： | 1 |
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