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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | In vitro migration of cytotroph- oblasts through a decidual endothelial monolayer: the role of matrix metalloproteinases 显示文摘 | Campbell S Rowe J Jackson C J | 2003 | Placenta2003，24，： | 1 |
| 3 | Convexity Subarachnoid Hemorrhage with Pi B Positive Pet Scans:Clinical Features and Prognosis显示文摘 | Ly J V Singhal S Rowe C C | 2014 | J Neuroimaging2014，，3： | 1 |
| 4 | Experimen tal Investigation of Heat Transfer in Grinding显示文摘 | Rowe W B Black S C E Mills B | 1995 | CIRP Annals- Manufacturing Technology1995，44，1： | 1 |
| 5 | A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion显示文摘 | Rowe C L Connolly S A Chen J Jardetzky T S Longnecker R | 2013 | Virology2013，436，1： | 1 |
| 6 | Temperature Control in cBN Grinding显示文摘 | Rowe W B Black S C E Mills B | 1996 | Advanced Manufaeturing Technology1996，，12： | 1 |
| 7 | Seeing red? Putting sportswear in context显示文摘 | ROWE C HARRIS J M ROBERTS S C | 2005 | Nature2005，437，： | 1 |
| 8 | Local haemodynamics of arterial bypass graft anastomoses 显示文摘 | Rowe C S Carpenter T K How T V | 1999 | Proc Inst Mech Eng1999，213，5： | 1 |
| 9 | Convexity Sub- arachnoid Hemorrhage with PiB Positive Pet Scans: Clini- cal Features and Prognosis显示文摘 | Ly J V Singhal S Rowe C C | 2015 | J Neuroimaging2015，25，3： | 1 |
| 10 | Theoretic aspects of chiral separation in capillary electrophoresis 显示文摘 | WREN S A C ROWE R C | 1992 | J Chromatrogr1992，603，： | 1 |
| 11 | Head - to - head comparison of 11C -PiB and 18F- AZD4694 for beta -amyloid imaging in aging and dementia显示文摘 | Rowe C Pejoska S Mulligan RS | 2012 | Alzheimers Dement2012，，4： | 1 |
| 12 | Design, synthesis and evaluation of furanocoumarin monomers as inhibitors of CYP3A4 显示文摘 | ROW E C BROWN S A STACHULSKI A V | 2006 | Org Biomol Chem2006，4，10： | 1 |
| 13 | Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death 显示文摘 | Henderson S Rowe M Gregory C | 1991 | Cell1991，65，7： | 1 |
| 14 | Identification of host-specific colonisation factors of Salmonella enterica serovar Typhimurium 显示文摘 | Morgan E Campbell J D Rowe S C | 2004 | Mol Microbiol2004，54，： | 1 |
| 15 | Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia显示文摘 | DiNardo C D Propert K J Loren A W Paietta E Sun Z X Levine R L Straley K S Yen K Patel J P Agresta S Abdel-Wahab O Perl A E Litzow M R Rowe J M Lazarus H M Fernandez H F Margolis D J Tallman M S Luger S M Carroll M | 2012 | Blood2012，121，24： | 1 |
| 16 | Optimal grid-free path planning across arbitrarily contoured terrain with anisotropic friction and gravity effects 显示文摘 | Rowe N C Ross R S | 1990 | IEEE Trans on Robotics and Automation1990，6，5： | 1 |
| 17 | Embolotherapy for pelvic congestion syndrome:long-term results显示文摘 | KIM H S MALHOTRA A D ROWE P C | 2006 | J Vasc Interv Radiol2006，17，21： | 1 |
| 18 | Sibling Delinquency and the FamilyEnvironment: Shared and Unshared Influences显示文摘 | Rowe D C Rodgers J L Meseck-Bushey S | 1992 | Child Development1992，63，： | 1 |
| 19 | Experimental investigation of heat transfer in grinding显示文摘 | Rowe W B Black S C E Qi H S | 1995 | Annals of the CIIIP1995，44，1： | 1 |
| 20 | Nothing Succeeds Like Succession: A Critical Re view of Leader Succession Literature since 1994 显示文摘 | GIAMBATISTA R C ROWE W G RIAZ S | 2005 | Leadership Quarterly2005，16，6： | 1 |
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