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	题名	作者	年代	出处	被引量
1	血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.	Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A	2014	中华神经外科疾病研究杂志2014，13，3：	6
2	Neural mechanisms involved in the delay of gastric emptying and gastrointestinal transit of liquid after thoracic spinal cord transection in awake rats 显示文摘	Gondim F A Rodrigues C L da-Graca J R	2001	Auton Neurosci2001，87，1：	1
3	Ti-Al-V powder metallurgy (PM) via the hydrogenation dehydrogenation (HDH) process 显示文摘	AZEVEDO C R F RODRIGUES D NETO F B	2003	Journal of Alloys and Compounds2003，353，12：	1
4	Three-Dimensional Modeling of Vertical-Horizontal Rolling Process显示文摘	XIONG Shang-wu Rodrigues J M C Martins P A F	2003	Finite Elements in Analysis and Design2003，39，：	1
5	Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid 显示文摘	Silva R F Rodrigues C M Brites D	2001	J Hepatol2001，34，3：	1
6	Spatial and temporal variation of phytoplankton in two subtropical Brazilian reservoirs 显示文摘	BORGES P A F TRAIN S RODRIGUES L C	2008	Hydrobiologia2008，607，：	1
7	Antifungal activi-ty of local anesthetics against Candida species显示文摘	Pina-Vaz C Rodrigues AC Sansonelty F	2000	Infect Dis ObstetGynecol2000，8，1：	1
8	The measurement of coal porosity with different gases显示文摘	Rodrigues C F Lenos M J	2002	International Journal of Coal Geology2002，48，34：	1
9	Three-dimensional modelling of the vertical- horizontal rolling process 显示文摘	XIONG Shang-wu Rodrigues J M C Martins P A F	2003	Finite Elements in Analysis and Design2003，39，11：	1
10	GeoSpray:A Geographic Routing Protocol for Vehicular Delay-tolerant Networks显示文摘	Soares V N G J Rodrigues J J P C Farahmand F	2014	Information Fusion2014，15，：	1
11	Thermal stress responses in antarctic yeast, glaciozyma antarctica PI12, characterized by real-time quantitative PCR显示文摘	Boo S Y Wong C M Rodrigues K F	2013	Polar Biology2013，36，3：	1
12	Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin显示文摘	Silva R F Rodrigues C M Brites D	2002	Pediatr Res2002，51，4：	1
13	NO~ storage on barium-contai- ning three-way catalyst in the presence of CO2 显示文摘	Rodrigues F Juste L Potvin C	2001	Catalysis Let- ters2001，72，12：	1
14	Antiulcerogenic activity of Alchornea castaneaefolia:Effects on somatostatin,gastrin and prostaglandin显示文摘	Hiruma-Lima C A Calvo T B Rodrigues C M Andrade F D Souza-Brito A R M	2006	Journal of Ethnopharmacology2006，104，1：	1
15	Application of the element free Galerkin method to the simulation of plane strain rolling显示文摘	Xiong S W Rodrigues J M C Martins P A F	2004	European Journal of Mechanic A/Solids2004，23，：	1
16	Evalu- ation of the knowledge of health professionals at a pediatric hospital regarding the use of metered - dose inhalers 显示文摘	Muchao F P Perin S L R R Rodrigues J C	2008	Jornal Brasileiro de Pneumologia2008，34，1：	1
17	Production of concentrated suspensions of thermophilic lactic acid bacteria in calcium alginate beads显示文摘	Champagne C P F Girard N Rodrigue	1993	Int Dairy1993，，3：	1
18	Effects that bovine sperm cryopreservation using two different extenders has on sperm membranes and chromatin显示文摘	Celeghini E C de Arruda R P de Andrade A F Nascimento J Raphael C F Rodrigues P H		0，，：	1
19	The struc- ture and resilience of financial market networks 显示文摘	KAUE D T DA F C RODRIGUES F A	2012	An Interdisciplinary Journal of Nonlinear Science2012，22，13：	1
20	An experimental study of the effect of surfactants on the free rise velocity of gas bubbles显示文摘	Rodrigue D De Kee D Chan Man Fong C F	1996	Journal of Non- Newtoman Fluid Mechanics1996，66，2：	1

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