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	题名	作者	年代	出处	被引量
1	血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.	Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A	2014	中华神经外科疾病研究杂志2014，13，3：	6
2	Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines 显示文摘	Brondani Da Rocha A Regner A Grivicich I	2004	Int J Oncol2004，25，3：	1
3	Urinary imerleukin-18 and urinary neutrephil gdatinase-associated lipocalin predict acute kid- ney injury following pulmonary valve replacement prior to serum creatinine 显示文摘	Buelow MW Dall A Regner K	2012	Congenit Heart Dis2012，7，5：	1
4	Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?显示文摘	da Rocha AB Mans DR Regner A	2002	Oncologist2002，7，1：	1
5	Molecular markers for genotyping graperine and for identifying clones of traditional varieties显示文摘	REGNER F STADLBAUER A EISENBELD C	2001	Acta Horticulturae2001，546，：	1
6	The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing quillaja saponin components QH-A, QH-C and ISCOPREPTMT03显示文摘	HU K F REGNER M SIEGRIST C A	2005	FEMS Immunol Med Microbiol2005，43，2：	1
7	Regeneration of transgenic plants of Prunus armeniaca containing the coat protein gene of Plum Pox Virus显示文摘	da CAMARA MACHADO M L da CAMARA MACHADO A HANZER V WEISS H REGNER F STEINKELINER H	1992	Plant Cell Rep1992，11，：	1
8	TCR down-regulation boosts T-cell-mediated eytotoxieity and protection against poxvirus infections显示文摘	Hansen A K Regner M Bonefeld C M	2011	Eur J Immanol2011，41，7：	1
9	Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines显示文摘	Brondani A Regner A Grivicich I	2012	Int J Oncol2012，33，3：	1
10	Fibulin-5 initiates epithelial-mesenchymal transition ( EMT ) and enhances EMT induced by TGF-beta in mammary epithelialcells via a MMP-dependent mechanism显示文摘	LEE Y H ALBIG A R REGNER M	2008	Carcinogenesis2008，29，12：	1
11	Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines 显示文摘	BRONDANI DA ROCHA A REGNER A	2004	Int J Oncol2004，25，3：	1
12	IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain irnjury显示文摘	Dalla Libera AL Regner A de Paoli J		0，，04：	1
13	Increased serum S100beta protein concentrations following severe head injury in humans: a biochemical marker of brain death显示文摘	Regner A Kaufman M Friedman G	2001	Neuroreport2001，12，4：	1
14	IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain injury显示文摘	Dalla Libera A L Regner A De Paoli J	2011	Brain Injury2011，25，4：	1
15	Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism 显示文摘	Lee Y H Albig A R Regner M	2008	Carcinogenesis2008，29，12：	1
16	Urinary interleukin-18 and urinary neutrophil gelatinase- associated lipocalin predict acute kidney injury following pulmona- ry valve replacement prior to serum greatinine显示文摘	Buelow MW Dall A Regner K Weinberg C Bartz PJ Sowinski J	2012	Congenit Heart Dis2012，7，5：	1
17	Radioresistance is associated to increased HSP70 content in human glioblastoma cell lines 显示文摘	Brondani DA Rocha A Regner A	2004	Int J Oncol2004，25，：	1
18	Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial ceils via a MMP- dependent mechanism 显示文摘	Lee Y H Albig A R Regner M	2008	Carcinogenesis2008，29，12：	1
19	Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines显示文摘	Brondani Da Rocha A Regner A	2004	Int J Oncol2004，25，：	1
20	Radioresistance is associated to increased Hsp70 content in human glioblastoma cell lines 显示文摘	Brondani DA Rocha A Regner A	2004	Int J Oncol2004，25，3：	1

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