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3篇 您的检索式：作者名="Rodrigue Dessein"

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		题名	作者	年代	出处	被引量
	1	Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease显示文摘Antimicrobial peptides,including defensins,are essential effectors in host defence and in the maintenance of immune homeostasis.Clinical studies have linked the defective expression of both α-and β-defensin to the reduced killing of certain microorganisms by the intestinal mucosa of patients suffering from ileal and colonic Crohn's disease(CD),respectively.Only recently have the events leading to defective expression of defensins in CD been further elucidated,and are discussed herein.These events may account for CD-associated alterations in the microbiome and may subsequently precipitate the development of granulomatous inflammatory lesions in genetically-predisposed patients.We also address how these discoveries may pave the way for the development of a molecular medicine aimed at restoring gut barrier function in CD.	Mathias Chamaillard Rodrigue Dessein	2011	World Journal of Gastroenterology2011，17，5：	5
	2	Prevention and Treatment of Colitis With Lactococcus lactis Secreting the Immunomodulatory Yersinia LcrV Protein显示文摘	Benoit Foligne Rodrigue Dessein Michael Marceau Sabine Poiret Mathias Chamaillard Bruno Pot Michel Simonet Catherine Daniel	2007	Gastroenterology2007，，3：	1
	3	NODs in defence :from vulnerable antimicrobial peptides to chronic inflammation 显示文摘	Laurent Peyrin-Biroulet Cecile Vignal Rodrigue Dessein	2006	Trends in Microbiology2006，14，100：	1

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