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| 1 | AME证据系列001--转化医学协会:脓毒症诊断和早期识别的临床实践指南显示文摘脓毒症是一种由感染引起的异质性疾病,感染触发了一系列复杂的局部或者全身的免疫炎症反应,引起多器官功能衰竭,发病率和病死率显著升高。由于至今仍然没有诊断脓毒症的金标准,所以脓毒症的临床诊断仍是一个难题。因此,脓毒症的临床诊断需要不断改变来满足临床和研究的要求。然而,尽管有许多新型的生物标记和筛选工具去预测脓毒症发生的风险,但是这些措施的诊断价值和有效性不足以让人满意,并且没有充分的证据去建议临床使用这些新技术。因此,脓毒症的临床诊断标准需要定期更新去适应不断产生的新证据。这篇综述旨在呈现当前脓毒症的诊断和早期识别方面的最新研究证据。临床运用不同的诊断方法的推荐意见依赖于推荐、评价、发展和评估分级体系(Grades of Recommendation Assessment,Development and Evaluation,GRADE),因为大部分的研究是观察性研究,并没有对这些方法进行可靠评估,采用的是两步推理方法。未来需要更多研究来确认或者反驳某一特殊的指标检测,同时应该直接采用相关病人的结果数据。 | Zhongheng Zhang Nathan J.Smischney Haibo Zhang Sven Van Poucke Panagiotis Tsirigotis Jordi Rello Patrick M.Honore Win Sen Kuan Juliet June Ray Jiancang Zhou You Shang Yuetian Yu Christian Jung Chiara Robba Fabio Silvio Taccone Pietro Caironi David Grimaldi Stefan Hofer George Dimopoulos Marc Leone Sang-Bum Hong Mabrouk Bahloul Laurent Argaud Won Young Kim Herbert D.Spapen Jose Rodolfo Rocco 张建成(译) 尚游(译) 钟鸣(校) | 2016 | 临床与病理杂志2016，36，10： | 5 |
| 2 | Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome显示文摘Considerable progress has been made over the last decades in the management of acute respiratory distress syndrome(ARDS).Mechanical ventilation(MV)remains the cornerstone of supportive therapy for ARDS.Lung-protective MV minimizes the risk of ventilator-induced lung injury(VILI)and improves survival.Several parame-ters contribute to the risk of VILI and require careful setting including tidal volume(V_(T)),plateau pressure(P_(plat)),driving pressure(ΔP),positive end-expiratory pressure(PEEP),and respiratory rate.Measurement of energy and mechanical power allows quantification of the relative contributions of various parameters(V_(T),P_(plat),ΔP,PEEP,respiratory rate,and airflow)for the individualization of MV settings.The use of neuromuscular blocking agents mainly in cases of severe ARDS can improve oxygenation and reduce asynchrony,although they are not known to confer a survival benefit.Rescue respiratory therapies such as prone positioning,inhaled nitric oxide,and extracorporeal support techniques may be adopted in specific situations.Furthermore,respiratory weaning protocols should also be considered.Based on a review of recent clinical trials,we present 10 golden rules for individualized MV in ARDS management. | Denise Battaglini Marco Sottano Lorenzo Ball Chiara Robba Patricia R.M.Rocco Paolo Pelosi | 2021 | Journal of Intensive Medicine2021，1，1： | 3 |
| 3 | An environmentally sustainable decision model for urban solid wsate management显示文摘 | COSTI P MINCIARDI R ROBBA M | 2004 | Waste Management2004，24，3： | 1 |
| 4 | A multiobjective approach for solid waste management显示文摘 | Mincirardi R Paolucci M Robba M | 2002 | Mathematical Programming2002，，： | 1 |
| 5 | Characterization and composition of commercial TiO2-V2O5 -WO3 SCR catalysts显示文摘 | ALEMANY L J BERTI F BUSCA G RAMIS G ROBBA D TOLEDO G P TROMBETTA M | 1996 | Appl Catal B1996，10，4： | 1 |
| 6 | Assessing the use of the mitochondrial cox1 marker for use in DNA bareoding of red algae(Rhodophyta) 显示文摘 | Robba L Russell S J Barker G L | 2006 | American Journal of Botany2006，93，8： | 1 |
| 7 | An environmentally sustainable decision model for urban solid management显示文摘 | P Costi R Minciardi M Robba | 2004 | Waste Management2004，24，： | 1 |
| 8 | Synthesis de 6,7-dihydro- 5H-pyrimidinocarbazoles and 7H-pyrimidino carbzoles 显示文摘 | Lancelot JC Gazengel JM Robba M | 1983 | Chem Pharm Bull1983，31，8： | 1 |
| 9 | A multiobjective approach for solid waste management显示文摘 | MINCIRARDI R PAOLUCCI M ROBBA M | 2002 | Mathematical Programming2002，25，： | 1 |
| 10 | An Environmentally Sustainable Decision Model for Urban Solid Management 显示文摘 | P Costi R Minciardi M Robba etal | 2004 | Waste Management2004，24，： | 1 |
| 11 | Chemical, structural and mechanistic aspects on NOx SCR over commercial and model oxide catalysts显示文摘 | LIETTI L RAMIS G BERTI F TOLEDO G ROBBA D BUSCA G FORZATTI P | 1998 | Catal Today1998，42，1： | 1 |
| 12 | Erythropoietin:a new perspective in cardiovascular therapy显示文摘 | Raddino R Robba D Caretta G | | 0，，04： | 1 |
| 13 | An Environment Sustainbble Decision Model for Urban Solid Waste Mangagement显示文摘 | P Costi R Minciordi M Robba | 2004 | Waste Management2004，24，3： | 1 |
| 14 | Optimizing forest biomass exploitation for energy supply at a regional level显示文摘 | Freppaz D Minciardi R Robba M | 2004 | Biomass and Bioenergy2004，26，1： | 1 |
| 15 | Erythropoietin: a new perspective in cardiovascular therapy显示文摘 | Raddino R Robba D Caretta G | 2008 | Monaldi Arch Chest Dis2008，70，4： | 1 |
| 16 | Thermographic inspection of TBC coated gas turbine blades: discrimination between coating over-thicknesses and adhesion defects 显示文摘 | Marinetti S Robba D Cernuschi F | 2007 | Infrared Physics & Technology2007，49，3： | 1 |
| 17 | Solid waste management in urban areas:development and application of a decision support system显示文摘 | Fiorucci P Minciardi R Robba M | 2003 | Resources Conservation and Recycling2003，37，4： | 1 |
| 18 | An environmentally sustainable decision model for urban solid waste management显示文摘 | Costi P Minciardi R Robba M | 2004 | Waste Management2004，24，3： | 1 |
| 19 | Characterization and composition of commercial V2O5 -WO3 -TiO2 SCR catalysts显示文摘 | ALEMANY L J BERTI F BUSCA G RAMIS G ROBBA D TOLEDO G P TROMBETTA M | 1996 | Appl Catal B: Environ1996，10，4： | 1 |
| 20 | Effects of the hypolipidemic drug nafenopin on the zona glomerulosa of the rat adrenal cortex:morphological counterparts of functional alterations显示文摘 | Robba C Mazzocchi G Gottardo G | 1986 | Anat Anz1986，161，1： | 1 |
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