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	题名	作者	年代	出处	被引量
1	Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets显示文摘AIM: To investigate the effect of protein-energy malnutrition on intestinal barrier function during rotavirus enteritis in a piglet model.METHODS: Newborn piglets were allotted at day 4 of age to the following treatments:(1) full-strength formula(FSF)/noninfected;(2) FSF/rotavirus infected;(3) half-strength formula(HSF)/noninfected;or(4) HSF/rotavirus infected.After one day of adjustment to the feeding rates,pigs were infected with rotavirus and acute effects on growth and diarrhea were monitored for 3 d and jejunal samples were collected for Ussingchamber analyses.RESULTS: Piglets that were malnourished or infected had lower body weights on days 2 and 3 post-infection(P < 0.05).Three days post-infection,marked diarrhea and weight loss were accompanied by sharp reductions in villus height(59%) and lactase activity(91%) and increased crypt depth(21%) in infected compared with non-infected pigs(P < 0.05).Malnutrition also increased crypt depth(21%) compared to full-fed piglets.Villus:crypt ratio was reduced(67%) with viral infection.There was a trend for reduction in transepithelial electrical resistance with rotavirus infection and malnutrition(P = 0.1).3H-mannitol flux was significantly increased(50%;P < 0.001) in rotavirus-infected piglets compared to non-infected piglets,but there was no effect of nutritional status.Furthermore,rotavirus infection reduced localization of the tight junction protein,occludin,in the cell membrane and increased localization in the cytosol.CONCLUSION: Overall,malnutrition had no additive effects to rotavirus infection on intestinal barrier function at day 3 post-infection in a neonatal piglet model.	Sheila K Jacobi Adam J Moeser Anthony T Blikslager J Marc Rhoads Benjamin A Corl Robert J Harrell Jack Odle	2013	World Journal of Gastroenterology2013，19，31：	4
2	Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence:two double-blind randomized clinical trials显示文摘	Grabowski J Rhoades H Stotts A	2004	Neuropsychopharmacology2004，29，5：	1
3	Microbial fuel cell using anaerobic respiration as an anodic reaction and biomineralized manganese as a cathodic reactant 显示文摘	Rhoads A Beyenal H Lewandowski Z	2005	Environ Sci Technol2005，39，12：	1
4	Molecular physiology of sodium-glucose cotransporters显示文摘	Hediger M A Rhoads D B	1994	Physiol Rev1994，74，：	1
5	Alpha-satellite DNA and vector composition influence rates of human artificial chromosome formation显示文摘	Grimes B R Rhoades A A Willard H F	2002	Mol Ther2002，5，：	1
6	A role for HOX A5 in regulating angiogenesis and vascular patterning显示文摘	Rhoads K Arderiu G Charboneau A	2005	Lymphat Res Biol2005，3，4：	1
7	Calmodulin signaling via IQ motif显示文摘	Bhler M Rhoads A	2002	FEBS letter2002，513，：	1
8	Overexpression of eukaryotic protein synthesis initiation factor 4E in I-IeLa cells results in aberrant growth and morphology显示文摘	Benedetti A Rhoads R E		0，，：	1
9	Abnormal glucose homeostasis due to chronic hyperresistinemia 显示文摘	Rangwala S M Rich A S Rhoades B	2004	Diabetes2004，53，8：	1
10	查看详情显示文摘	RHOADES W A CHILDS R L		0，，：	1
11	New weighted-difference formulation for discrete-ordinates calculations显示文摘	RHOADES W A ENGLE W W Jr	1977	Transactions of the American Nuclear Society1977，27，：	1
12	Inducible nitric oxide synthase mediates early epithelial repair of porcine ileum 显示文摘	Gookin J L Rhoads J M Argenzio R A	2002	American Journal of Physiology-Gastrointes- tinal and Liver Physiology2002，283，1：	1
13	The use of saline waters for crop production FAO irrigation and drainage paper 48显示文摘	Rhoades J D Kandiah A Mashali A M	1992	FAO Rome1992，，：	1
14	Sequence motif and calmodulin recognition 显示文摘	Rhoads A R Freiedberg F	1997	FASEB J1997，11，：	1
15	Market share as a source of market power:implications and some evidence显示文摘	STEPHEN A RHOADES	1985	Journal of Economics and Business1985，37，4：	1
16	Determining soil salinity fromsoil electrical conductivity using different models and estimates显示文摘	Rhoades J D Shouse P J Alves N A	1990	Soil Sci Soc Am J1990，54，：	1
17	Serologic types and physiologic characteristics of 46 avian Pasteurella anatipestifer eultures显示文摘	Brogden K A Rhoades K R Rimler R B	1982	Avian Disease1982，26，4：	1
18	Soil electrical conductivity and soil salinity:new formula- tions and calibrations 显示文摘	Rhoades J D Manteghi N A Shouse P J	1989	Soil Science Society of America Journal1989，53，2：	1
19	The use of saline waters for crop production显示文摘	Rhoades J D Kandiah A Mashali A M	1992	FAO Irrigation and Drainage Paper1992，，：	1
20	A note on the market share-profitability relationship显示文摘	KURTZ ROBERT STEPHEN A RHOADES	1992	Review of Industrial Organization1992，7，1：	1

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