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301篇 您的检索式：作者名="Reis H"

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	题名	作者	年代	出处	被引量
1	AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma显示文摘Intrahepatic cholangiocarcinomas (ICC) are neoplasms that originate from cholangiocytes and can occur at any level of the biliary tree. Surgical resection is the current therapy of choice for this highly aggressive cancer. However, the 5-year survival still is poor, with high recurrence rates. Due to the intrahepatic growth a signifi cant proportion of patients present with advanced disease and are not candidates for curative surgery or transplantation. The existing palliative options are of limited benefit and there is a great necessity for novel therapeutic options. In this article we review the role of the phosphoinositide 3-kinase(PI3K)/ AKT and extracellular regulated kinase (ERK) signaling pathways in ICC and present new data on the prognostic value of these protein kinases. Finally, we discuss future upcoming therapeutic options based on targeting these signaling pathways.	KJ Schmitz H Lang J Wohlschlaeger GC Sotiropoulos H Reis KW Schmid HA Baba	2007	World Journal of Gastroenterology2007，13，48：	8
2	Innate antiviral responses by means of TLRT-mediated recognition of single-stranded RNA显示文摘	Diebold S S Kaisho T Hemmi H Akira S Reis e Sousa C	2004	Science2004，303，：	1
3	Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo)than in secondary glioblastomas显示文摘	Fujisawa H Reis RM Nakamura M	2000	Lab Invest2000，80，1：	1
4	A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors 显示文摘	Reis H Putter C Megger DA	2015	Biochim Biophys Acta2015，1854，6：	1
5	Lipases at interfaces: a review 显示文摘	Reis P Holmberg K Watzke H	2009	Advances in Colloid and Interface Sci- ence2009，147，：	1
6	Coherent control of pulsed X-ray beams显示文摘	DeCamp M F Reis D A Bucksbaum P H	2001	Nature2001，413，6858：	1
7	Process development for generating high purity hydrogen by using supported palladium membrane reactor as steam reformer显示文摘	Lin Y M Rei M H	2000	Int J Hydrogen Energy2000，25，：	1
8	Chapter 11 Biomonitors in use: lichens and metal air pollution显示文摘	WOLTERBEEK H T GARTY J REIS M A	2003	Trace Metals and Other Contaminants in the Environment2003，6，：	1
9	Serum disposition of sertraline, N-desmethylsertraline and paroxetine : a pharmacokinetic evaluation of repeated drug concentration ts during 6 months of treatment for major depression 显示文摘	REIS M ABERG-WISTEDT A AGREN H	2004	Hum Psychopharmacol2004，19，5：	1
10	Clarification and purification of aqueous Stevia extract using membrane separation process 显示文摘	REIS M H M SILVA F V ANDRADE C M G	2009	Journal of Food Process Engineering2009，32，3：	1
11	Daily well - being: The role of autonomy, competence, and re- latedness 显示文摘	REIS H T SHELDON K M GABLE S L	2000	Personality and Social Psychology Bulletin2000，26，4：	1
12	Effects of somatotropin and substrates on patterns of liver me- tabolism in lactating dairy cattle 显示文摘	KNAPP J R FREETLY H C REIS B L	1992	Journal of Dairy Science1992，75，4：	1
13	Sulindac inhibits neointimal formation after arterial injury in wild-type and apolipoprotein E-deficient mice显示文摘	Roque M Dansky H	2000	Proc Natl Acad Sci USA2000，97，12：	1
14	EIS investigation on A1 5052 alloy surface preparation for self-assembling monolayer显示文摘	Reis F M DeMelo H G Costa I	2006	Electrochimica Acta2006，51，：	1
15	Casagrande,D R Energetic pro-tein supplementation on heifers performance in grazing during the finish phase显示文摘	Moretti M H Reis R A		0，，03：	1
16	Optimal location of control valves in pipe networks by genetic algorithm显示文摘	Reis L F R Porto R M Chaudhry F H	1997	Water Resource Planning Management1997，123，6：	1
17	Intravenous iron therapy as a possible risk factor for atherosclerosis in end-stage renal disease显示文摘	Reis KA Guz G Ozdemir H	2005	Int Heart J2005，46，：	1
18	Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma ( EPPK ) 显示文摘	Reis A Hennies H C Langbein L	1994	Nat Genet1994，6，2：	1
19	A prototype instrument to evaluate fatigue damage in the sidewalls of steel-belted radial truck tires显示文摘	Dos H L Reis M Golko P J	1998	Tire Science and Technology1998，26，1：	1
20	Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas 显示文摘	Fujisawa H Reis RM Nakamura M	2000	Lab Invest2000，80，1：	1

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