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| 1 | 体外诱导人类B细胞分泌HLA抗体的实验研究显示文摘目的:探索体外诱导人类B细胞产生特异性HLA抗体的理想培养条件。方法:以EBV转化致敏肾移植患者B淋巴细胞系(BLCL)为模型,采用ELISA和ELISPOT方法,比较3种培养体系:(1)RPMI1640+抗OPTI单克隆抗体(mAb);(2)RPMI1640+0·1mmol/L非必需氨基酸液+1mmol/L丙酮酸钠+40mg/L转铁蛋白;(3)Hybridoma无血清培养液,以及3种培养条件:(1)对照组(仅培养液),(2)培养液+rIL-4+rIL-10+鼠抗人CD40(α-CD40),(3)培养液+rIL-4+rIL-10+重组人CD40配体(CD40L),人类B细胞产生免疫球蛋白(Ig)和特异性抗HLA抗体的能力。结果:BLCL细胞在Hybridoma SFM培养体系所产生的IgG和IgM浓度分别为25·2~28·1mg/L和7·14~7·95mg/L,高于其他两种培养条件(P<0·05)。BLCL细胞在添加了IL-4、IL-10和α-CD40或CD40L的杂交瘤无血清培养液中能产生特异性抗HLA-I抗体,所获得的斑点频数分别为3·06/每104个BLCL细胞和3·55/每104个BLCL细胞,高于对照组(1·77/每104个BLCL细胞)。结论:BLCL细胞在杂交瘤无血清培养液中和添加了IL-4、IL-10和α-CD40或CD40L的培养条件下,提高分泌IgG和IgM的能力和特异性抗HLA-I类分子的抗体。 | 廖爱华 Vera Rebmann Hans Grosse-Wilde 王燕 张玲 | 2007 | 细胞与分子免疫学杂志2007，23，7： | 2 |
| 2 | HLA-G is a potential tumor marker in malignant ascites显示文摘 | Singer G Rebmann V Chen YC | 2003 | Clin Cancer Res2003，9，2： | 1 |
| 3 | Inter leukin-2/interferon alpha2a /13-retinoie acid-based ehemoimmunotherapy in advanced renal cell earcino ma:results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)显示文摘 | Atzpodien J Kirchner H Rebmann U | 2006 | gr J Cancer2006，95，4： | 1 |
| 4 | HLA-DR expression and soluble HLA-DR levels in septic patients after trauma 显示文摘 | Ditschkowski M Kreuzfelder E Rebmann V | 1999 | Ann Surg1999，229，2： | 1 |
| 5 | Preventing catheter-associated urinary tract infections An executive summary of the Association for Professionals in Infection Control and Epidemiology, Inc, Elimination Guide显示文摘 | Rebmann T Greene LR | 2010 | American Journal of Infection Control2010，38，8： | 1 |
| 6 | Estimates of the Annual Net Carbon and Water Exchange of Forests: The EUROFLUX Methodology显示文摘 | M. Aubinet A. Grelle A. Ibrom ü. Rannik J. Moncrieff T. Foken A.S. Kowalski P.H. Martin P. Berbigier Ch. Bernhofer R. Clement J. Elbers A. Granier T. Grünwald K. Morgenstern K. Pilegaard C. Rebmann W. Snijders R. Valentini T. Vesala | 2000 | Advances in Ecological Research2000，，： | 1 |
| 7 | HLA-G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia显示文摘 | NUCKEL H REBMANN V DURIG J | 2005 | Blood2005，105，： | 1 |
| 8 | Altered transcription of a defective measles virus genome derived from a diseased human brain 显示文摘 | Cattaneo R G Rebmann A Schmid K | 1987 | EMBO J1987，6，： | 1 |
| 9 | Rapid evaluation of soluble HLA - G levels in supernatants of in vitro fertilized embryos显示文摘 | Rebmann V Switala M Eue I | 2007 | Hu- man Immunology2007，68，4： | 1 |
| 10 | Quality analysis applied on eddy covariance measurements at complex forest sites using footprint modelling显示文摘 | C. Rebmann M. G?ckede T. Foken M. Aubinet M. Aurela P. Berbigier C. Bernhofer N. Buchmann A. Carrara A. Cescatti R. Ceulemans R. Clement J. A. Elbers A. Granier T. Grünwald D. Guyon K. Havránková B. Heinesch A. Knohl T. Laurila B. Longdoz B. Marcolla T. M | 2005 | Theoretical and Applied Climatology (-)2005，，2： | 1 |
| 11 | Quality analysis applied on eddy covariance measurements at complex forest sites using footprint modelling显示文摘 | C. Rebmann M. G?ckede T. Foken M. Aubinet M. Aurela P. Berbigier C. Bernhofer N. Buchmann A. Carrara A. Cescatti R. Ceulemans R. Clement J. A. Elbers A. Granier T. Grünwald D. Guyon K. Havránková B. Heinesch A. Knohl T. Laurila B. Longdoz B. Marcolla T. M | 2005 | Theoretical and Applied Climatology2005，，2： | 1 |
| 12 | Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma显示文摘 | Bukur J Rebmann V Grosse-Wilde H | 2003 | Cancer Res2003，63，14： | 1 |
| 13 | MR imaging in the diagnosis of ectopic ureteral insertion of a dysplastic kidney显示文摘 | Rebmann S Strauss A Vosshenrich R | 2004 | Der Urologe A2004，43，8： | 1 |
| 14 | Soluble MICA as an independent prognostic factor for the overall survival and progression- free survival of muhiple myeloma patients显示文摘 | Rebmann V Schutt P Brandhorst D | 2007 | Clin Immunol2007，123，1： | 1 |
| 15 | Preventing catheter - associated urina- ry tract infections : An executive summary of the Association for Professionals in Infection Control and Epidemiology, Inc, Elimi- nation Guide 显示文摘 | Rebmann T Greene LR | 2010 | American journal of infection control2010，38，8： | 1 |
| 16 | HLA - G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia 显示文摘 | Nuckel H Rebmann V Durig J Duhrsen U Grosse- Wilde H | 2005 | Blood2005，105，4： | 1 |
| 17 | HLA-G expression in malignant melanoma显示文摘 | Rebmann V Wagner S Grosse-Wilde H | 2007 | Semin Cancer Biol2007，17，6： | 1 |
| 18 | In vivo identification of an HLA ‐ G complex as ubiquitinated protein circulating in exosomes显示文摘 | Estibaliz Alegre Vera Rebmann Joel LeMaoult Carmen Rodriguez Peter A. Horn Angel Díaz‐Lagares José I. Echeveste Alvaro González | 2013 | Eur J Immunol2013，，7： | 1 |
| 19 | Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-alpha im- munotherapy显示文摘 | Ugurel S Rebmann V Ferrone S | 2001 | Cancer2001，92，2： | 1 |
| 20 | Soluble HLA-G is an independent factor for the prediction of pregnancy outcome after ART: a German multi-centre study显示文摘 | Rebmann V Switala M Eue I | 2010 | Hum Reprod2010，25，7： | 1 |
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