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| 1 | Physical rehabilitation for lung transplant candidates and recipients: An evidence-informed clinical approach显示文摘Physical rehabilitation of lung transplant candidates and recipients plays an important in optimizing physical function prior to transplant and facilitating recovery of function post-transplant. As medical and surgical interventions in lung transplantation have evolved over time, there has been a demographic shift of individuals undergoing lung transplantation including older individuals, those with multiple co-morbidites, and candidates with respiratory failure requiring bridging to transplantation. These changes have an impact on the rehabilitation needs of lung transplant candidates and recipients. This review provides a practical approach to rehabilitation based on research and clinical practice at our transplant centre. It focuses on functional assessment and exercise prescription during an uncomplicated and complicated clinical course in the pre-transplant, early and late post-transplant periods. The target audience includes clinicians involved in pre- and posttransplant patient care and rehabilitation researchers. | Lisa Wickerson Dmitry Rozenberg Tania Janaudis-Ferreira Robin Deliva Vincent Lo Gary Beauchamp Denise Helm Chaya Gottesman Polyana Mendes Luciana Vieira Margaret Herridge Lianne G Singer Sunita Mathur | 2016 | World Journal of Transplantation2016，6，3： | 8 |
| 2 | CT diagnosis of recurrence after pancreatic cancer:Is there a pattern?显示文摘AIM:To investigate predilection sites of recurrence of pancreatic cancer by computed tomography(CT)in follow-up after surgery. METHODS:Seventy seven patients with recurrence after pancreatic cancer surgery were retrospectively identified.The operative technique,R-status,T-stage and development of tumor markers were evaluated. Two radiologists analyzed CT scans with consensus readings.Location of local recurrence,lymph node recurrence and organ metastases were noted.Surgery and progression of findings on follow-up CT were con-sidered as reference standard. RESULTS:The mean follow-up interval was 3.9± 1.8 mo,with a mean relapse-free interval of 12.9± 10.4 mo.The predominant site of recurrence was local (65%),followed by lymph node(17%),liver metastasis (11%)and peritoneal carcinosis(7%).Local recurrence emerged at the superior mesenteric artery(n=28),the hepatic artery(n=8),in an area defined by the surrounding vessels:celiac trunk,portal vein,inferior vena cava(n=22),and in a space limited by the mesenteric artery,portal vein and inferior vena cava(n=17). Lymph node recurrence occurred in the mesenteric root and left lateral to the aorta.Recurrence was confirmed by surgery(n=22)and follow-up CT(n=55).Tumor markers[carbohydrate antigen 19-9(CA19-9),carcinoembryonic antigen(CEA)]increased in accordance with signs of recurrence in most cases(86%CA19-9;79.2% CEA). CONCLUSION:Specific changes of local and lymph node recurrence can be found in the course of the cardinal peripancreatic vessels.The superior mesenteric artery is the leading structure for recurrence. | Tobias Heye Nicola Zausig Miriam Klauss Reinhard Singer Jens Werner Gtz Martin Richter Hans-Ulrich Kauczor Lars Grenacher | 2011 | World Journal of Gastroenterology2011，17，9： | 6 |
| 3 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004，7，4： | 3 |
| 4 | Postoperative impairment mucous transport in the lung 显示文摘 | Gamsu G Singer M M Vincent H H | 1976 | Am Rev Respir Dis1976，114，： | 2 |
| 5 | HLA-G is a potential tumor marker in malignant ascites显示文摘 | Singer G Rebmann V Chen YC | 2003 | Clin Cancer Res2003，9，2： | 1 |
| 6 | Ikawa M, et aL A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA显示文摘 | Tiscornia G Singer O | 2003 | Proc Natl Acad Sci USA2003，100，4： | 1 |
| 7 | Determinants of portfolio performance Ⅱ: An update 显示文摘 | BRINSON G P SINGER B D GILBERT L BEE- BOWER G L | 1991 | Financial Analysis Journal1991，47，3： | 1 |
| 8 | The influence of hot working on the subsequent recrystallization oI a dispersion strengthened superalloy-MA 6000 显示文摘 | SINGER R F GESSINGER G H | 1982 | Metall Trans A1982，13，8： | 1 |
| 9 | The ability of clove oil and MS-222 to minimize handling stress in rainbow trout ( Oncorhynchus mykiss Walbaum ) 显示文摘 | WAGNER G N SINGER T D MCKINLEY R S | 2003 | Aquaculture Research2003，34，： | 1 |
| 10 | Intramedullary nailing for the treatment of dislocated pedi- atric radial neck fractures 显示文摘 | Eberl R Singer G Fruhmann J Saxena A Hoellwarth ME | 2010 | Eur J Pediatr Surg2010，20，4： | 1 |
| 11 | Mutatiom in BRAF and KRAS characterize the development of lowgrade ovarian serous carcinoma显示文摘 | Singer G Oldt R 3rd Cohen Y | 2003 | J Natl Cancer Inst2003，95，6： | 1 |
| 12 | Evaluation of the efficacy and dose-response relationship of dexibuprofen in patients with osteoarthritis of the hip and comparison with racemic ibuprofen using the WOMAC osteoarthritis index显示文摘 | Mayrhofer F Klein G | 2000 | Int J Clin Pharmacol Ther2000，38，1： | 1 |
| 13 | A general method forgene knockdown in mice by using lentiviral vectors expressingsmall interfering RNA显示文摘 | Tiscornia G Singer O Ikawa M | 2003 | Proc Natl Acad Sci USA2003，100，： | 1 |
| 14 | Fstrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemi- cal study 显示文摘 | Reich O Singer C Hudelist G | 2007 | Pathol Res Pratt2007，203，2： | 1 |
| 15 | A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA显示文摘 | Tiscornia G Singer O Ikawa M | 2003 | Proc Natl Acad Sci USA2003，100，4： | 1 |
| 16 | Presence of nanobacteriain psammoma bodies of ovarian cancer; evidence for pathogeneticrole in intratumoral biomineralization 显示文摘 | Hudelist G Singer CF Kubista E | 2004 | Histopathology2004，45，6： | 1 |
| 17 | A general method for gene knockdown inmice by using lentiviral vectors expressing small interfering RNA显示文摘 | Tiscomia G Singer O Ikawa M | 2003 | Proc NatlAcad Sci U S A2003，100，： | 1 |
| 18 | Spectral reflectance properties of crusted soils under solar illumination 显示文摘 | ESCEL G LEVY G J SINGER M J | 2004 | Soil Science Society of America Journal2004，68，6： | 1 |
| 19 | Electro-optic phase modulation and optical second-harmonic generation in corona-poled polymer films 显示文摘 | Singer K D Kuzyk M G | 1988 | Applied Physics Letters1988，53，19： | 1 |
| 20 | A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA显示文摘 | Tiscornia G Singer O Ikawa M | 2003 | PNAS2003，100，： | 1 |
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