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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Scalable and efficient multi-label classification for evolving data streams显示文摘 | Read J Bifet A Holmes G PfahRINGER B | | 0，，1： | 1 |
| 3 | Placenta accreta:changing clinical aspects and outcome显示文摘 | Read J A Cotton D B Miler F C | 1980 | Obstet Gyuecol1980，56，1： | 1 |
| 4 | Respiratory in- fections显示文摘 | Cant A J Gordon S B Read R C | 2002 | J Med Mierobiol2002，51，11： | 1 |
| 5 | Phylogenetic relationships inthe subfamily Bovinae ( Mammalia:Artiodactyla) based on ribosomal DNA显示文摘 | WALL D A DAVIS S K READ B M | 1992 | Journal of Mammal1992，73，： | 1 |
| 6 | Physical properties of axenic maize root mucilage显示文摘 | Read D B Gregory P J Bell A E | 1999 | Plant and Soil1999，211，： | 1 |
| 7 | Evaluation of seven procedures for detection of abnormal milk due to mastitis显示文摘 | Read R B Reyes A L Bradshaw J G | 1969 | Journal of Dairy Science1969，52，13： | 1 |
| 8 | Explaining and predicting the impact of branding alliances and web site quality on initial consumer trust of e-commerce web sites显示文摘 | Lowry P B Vance A Moody G Beckman B Read A | | 0，，04： | 1 |
| 9 | Role for leptin in promoting glucose mobilization during acute hyperosmotic stress in teleost fishes显示文摘 | Baltzegar D A Reading B J Douros J D | 2014 | Journal of Endocrinology2014，220，： | 1 |
| 10 | Physical properties of axenicmaize root mucilage显示文摘 | Read D B Gregory P J Bell A E | 1999 | Plant Soil1999，211，： | 1 |
| 11 | Contact resistance in flat thin films 显示文摘 | READ M B LANG J H SLOCUM A H | 2009 | 55th IEEE Holm Conference on Electrical Contacts Vancouver British Colombia Canada2009，，： | 1 |
| 12 | Respiratory infections 显示文摘 | Cant A J Gordon S B Read R C | 2002 | J Med Microbiol2002，51，11： | 1 |
| 13 | Pan genome of the phytoplankton Emiliania underpins its global distribution显示文摘 | Read B A Kegel J Klute M J | 2013 | Nature2013，499，7457： | 1 |
| 14 | A simple model accounts for the response of disparity-tuned V1 neurons to anticorrelated images显示文摘 | READ J PARKER A J CUMMING B G | 2002 | Visual Neuroscience2002，，19： | 1 |
| 15 | Therapeutic potential of mesenchymal stem cells for severe acute lung injury显示文摘 | MATTHAY M A THOMPSON B T READ E J | | 0，，04： | 1 |
| 16 | Sequence development of a mixed carbonate-siliciclastic high-relief ramp, Mississippian, Kentucky, USA 显示文摘 | KHETANI A B READ J F | 2002 | Journal of Sedimentary Research2002，72，5： | 1 |
| 17 | Induction of phase variation events in the life cycle of the marine coccolithophorid Erniliania huxleyi 显示文摘 | Laguna R Romo J Read B A | 2001 | Appl Environ Microbiol2001，67，9： | 1 |
| 18 | Batch-incremental versus instance-incremental learning in dynamic and evolving data 显示文摘 | Read J Bifet A Pfahringer B | 2012 | Advances in Intelligent Data Analysis2012，7619，： | 1 |
| 19 | TRPC3 mediates pyrimidine receptor induced depolarization of cerebral artery显示文摘 | READING S A EARLEY S WALDRON B J | 2005 | Am J Physiol Heart Circ Physiol2005，288，： | 1 |
| 20 | IGF-Ⅰ and the Truncated Analogue des IGF-Ⅰ Enhance Growth in Rats after Gut Resection显示文摘 | LEMMEY A B MARTIN A A READ L C | 1991 | Physiology1991，260，： | 1 |
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