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| 1 | 显花植物在提高节肢动物天敌控制害虫中的生态功能显示文摘由于农业集约化生产引起的非作物生境减少和农业化学品的过量使用减弱了农田生态系统中害虫天敌的自然控制作用。合理而有效地利用显花植物可以为害虫天敌提供食物来源和庇护场所,从而能有效地提高天敌对害虫的自然控制能力、减少化学农药的使用量。本文综述了显花植物对天敌种群的促进作用及其在果园、蔬菜和粮食作物等害虫防治中应用的最新进展,同时对进一步利用显花植物提高农业生态系统稳定性的发展方向进行了讨论。 | 朱平阳 吕仲贤 Geoff Gurr 郑许松 Donna Read 杨亚军 徐红星 | 2012 | 中国生物防治学报2012，28，4： | 40 |
| 2 | Reflections on theoretical pragmatics显示文摘This paper provides a critical survey of theoretical pragmatics in contemporary linguistics. Among the topics that are addressed in the essay include the Anglo-American, and European Continental schools of thought; neo-Gricean pragmatic, and Relevance theories, the pragmatics-semantics interface; and the pragmatics-syntax interface. | HUANG Yan (Department of Linguistic Science, University of Reading, Reading RG6 6AA, England) | 2001 | 外国语2001，24，1： | 33 |
| 3 | Mechanisms for flowering plants to benefit arthropod natural enemies of insect pests: Prospects for enhanced use in agriculture显示文摘noncrop 产地的减小,杀虫剂的集中的使用和骚乱的高水平与集中的庄稼生产联系了简化耕作风景并且引起生物多样性的锋利的衰落。接着,这削弱节肢动物天赋敌人提供的生物控制生态系统服务。flowering 植物的战略使用能向生来的敌人提供以一种指向得好的方式提高植物生物多样性食物来源和躲蔽处在化学杀虫剂上改进生物控制和还原剂依赖。这篇文章在果园,蔬菜和领域庄稼为生来的敌人,害虫管理上的可能的不利效果,和 flowering 植物的实际应用程序考察导出植物的食物的各种各样的类型的营养的值,大多数研究的农业系统发生了。flowering 的有效使用种在 agroecosystem 最大化昆虫害虫的生物控制的为更多的前景好,但是看情况在上面在最佳的植物的选择上,种类有选择地在害虫种类上基于生来的敌人是的生态的由机制的信息赞成了。 | Zhong-Xian Lu Ping-Yang Zhu Geoff M. Gurr Xu-Song Zheng Donna M. Y. Read Kong-Luen Heong Ya-Jun Yang Hong-Xing Xu | 2014 | Insect Science2014，21，1： | 26 |
| 4 | Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3显示文摘AIM: To investigate the inhibitory role and the underlying mechanisms of sorafenib on signal transducer and activator of transcription 3 (STAT3) activity in hepatocellular carcinoma (HCC).METHODS: Human and rat HCC cell lines were treated with sorafenib. Proliferation and STAT3 dephosphorylation were assessed. Potential molecular mechanisms of STAT3 pathway inhibition by sorafenib were evaluated. In vivo antitumor action and STAT3 inhibition were investigated in an immunocompetent orthotopic rat HCC model.RESULTS: Sorafenib decreased STAT3 phosphorylationat the tyrosine and serine residues (Y705 and S727), but did not affect Janus kinase 2 (JAK2) and phosphatase shatterproof 2 (SHP2), which is associated with growth inhibition in HCC cells. Dephosphorylation of S727 was associated with attenuated extracellular signal-regulated kinase (ERK) phosphorylation, similar to the effects of a mitogen-activated protein kinase (MEK) inhibitor U0126, suggesting that sorafenib induced S727 dephosphorylation by inhibiting MEK/ERK signaling. Meanwhile, sorafenib could also inhibit Akt phosphorylation, and both the phosphatidylinositol-3-kinase (PI3K) inhibitor LY294002 and Akt knockdown resulted in Y705 dephosphorylation, indicating that Y705 dephosphorylation by sorafenib was mediated by inhibiting the PI3K/Akt pathway. Finally, in the rat HCC model, sorafenib signifi cantly inhibited STAT3 activity, reducing tumor growth and metastasis.CONCLUSION: Sorafenib inhibits growth and metastasis of HCC in part by blocking the MEK/ERK/STAT3 and PI3K/Akt/STAT3 signaling pathways, but independent of JAK2 and SHP2 activation. | Fang-Ming Gu, Quan-Lin Li, Qiang Gao, Jia-Hao Jiang, Xiao-Yong Huang, Jin-Feng Pan, Jia Fan, Jian ZhouFang-Ming Gu, Quan-Lin Li, Qiang Gao, Jia-Hao Jiang, Xiao-Yong Huang, Jin-Feng Pan, Jia Fan, Jian Zhou, Liver Cancer Institute, Zhongshan Hospital and Shanghai Medical School, Fudan University, Shanghai 200032, China Author contributions: Gu FM, Li QL and Gao Q contributed equally to this work Gu FM and Li QL performed the experi- ments and interpretation of the data and statistical analysis Zhou J and Gao Q contributed to the conception and design of the study Gu FM, Gao Q, Li QL and Zhou J wrote the manuscript Jiang JH, Huang XY, Pan JF and Fan J made substantial contri- bution to the design and conception of the study and interpreta- tion of data all authors read and approved the f inal manuscript. | 2011 | World Journal of Gastroenterology2011，17，34： | 18 |
| 5 | Tumor size as a prognostic factor in patients with advanced gastric cancer in the lower third of the stomach显示文摘AIM: To explore the impact of tumor size on outcomes in patients with advanced gastric cancer in the lower third of the stomach. METHODS: We retrospectively analyzed the clinical records of 430 patients with advanced gastric cancer in the lower third of the stomach who underwent distal subtotal gastrectomy and D2 lymphadenectomy in our hospital from January 1998 to June 2004. Receiver-operating characteristic (ROC) curve analysis was used to determine the appropriate cutoff value for tumor size, which was measured as maximum tumor diameter. Based on this cutoff value, patients were divided into two groups: those with large-sized tumors (LSTs) and those with small-sized tumors (SSTs). The correlations between other clinicopathologic factors and tumor size were investigated, and the 5-year overall survival (OS) rate was compared between the two groups. Potential prognostic factors were evaluated by univariate KaplanMeier survival analysis and multivariate Cox's propor-tional hazard model analysis. The 5-year OS rates in the two groups were compared according to pT stage and pN stage. RESULTS: The 5-year OS rate in the 430 patients with advanced gastric cancer in the lower third of the stomach was 53.7%. The mean ± SD tumor size was 4.9 ± 1.9 cm, and the median tumor size was 5.0 cm. ROC analysis indicated that the sensitivity and specificity results for the appropriate tumor size cutoff value of 4.8 cm were 80.0% and 68.2%, respectively (AUC=0.795, 95%CI: 0.751-0.839, P=0.000). Using this cutoff value, 222 patients (51.6%) had LSTs (tumor size ≥ 4.8 cm) and 208 (48.4%) had SSTs (tumor size<4.8 cm). Tumor size was significantly correlated with histological type (P=0.039), Borrmann type (P=0.000), depth of tumor invasion (P=0.000), lymph node metastasis (P=0.000), tumor-nodes metastasis stage (P=0.000), mean number of metastatic lymph nodes (P=0.000) and metastatic lymph node ratio (P=0.000). Patients with LSTs had a significantly lower 5-year OS rate than those with SSTs (37.1% vs 63.3%, P=0.000). Univariate analysis showed that depth of tumor invasion (c 2=69.581, P=0.000), lymph node metastasis (c 2=138.815, P=0.000), tumor size (c 2=78.184, P=0.000) and metastatic lymph node ratio (c 2=139.034, P=0.000) were significantly associated with 5-year OS rate. Multivariate analysis revealed that depth of tumor invasion (P=0.000), lymph node metastasis (P=0.019) and tumor size (P=0.000) were independent prognostic factors. Gastric cancers were divided into 12 subgroups: pT2N0; pT2N1; pT2N2; pT2N3; pT3N0; pT3N1; pT3N2; pT3N3; pT4aN0; pT4aN1; pT4aN2; and pT4aN3. In patients with pT2-3N3 stage tumors and patients with pT4a stage tumors, 5-year OS rates were significantly lower for LSTs than for SSTs (P<0.05 each), but there were no significant differences in the 5-year OS rates in LST and SST patients with pT23N0-2 stage tumors (P > 0.05). CONCLUSION: Using a tumor size cutoff value of 4.8cm, tumor size is a prognostic factor in patients with pN3 stage or pT4a stage advanced gastric cancer located in the lower third of the stomach. | Hong-Mei Wang, Chang-Ming Huang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Department of Gastric Surgery, Affiliated Union Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China Author contributions: Wang HM and Huang CM conceived of the study, analyzed the data, and drafted the manuscript Zheng CH, Li P and Xie JW helped revise the manuscript critically for important intellectual content Wang JB, Lin JX and Lu J helped collect data and design the study and all authors read and approved the final manuscript. | 2012 | World Journal of Gastroenterology2012，18，38： | 15 |
| 6 | 疝病学:历史现状和未来显示文摘疝修补术是一种常见手术,大多数医生认为这是一种小手术。但是有些医生却不这么认为。疝修补术的创造者是Bassini(1884),他发明了腹股沟疝的根治性治疗方法:切开腹股沟的三层,即腹内斜肌、腹横肌、腹横筋膜,进入了腹膜前间隙,以高位结扎疝囊和以上三层缝合至腹股沟韧带。这种手术方式只有2.7%的复发率,因此引起世界范围内的争相仿效。但同时问题也接踵而至,提睾肌仍然残留,没有切开的层面不缝合,没有重叠加强修补,采用提睾肌或腹直肌加强修补,使用筋膜瓣,减张切开。这种讹误使人们对Bassini的工作产生了怀疑。自1906年采用Russsel(lLancet,1906,2:1197-1203.)的疝囊结扎手术直到1953年。此后Shoudice诊所使Bassini原则重新流行,并被奉为疝修补的金标准而历时数十年。Cheatle引入了后路腹膜前疝修补术(BrMedJ,1920,2:68-69)。Acquaviva和Bourret设计了第一个植入假体(尼龙),后来被聚丙烯取代。这些贡献为Rives、Stoppa、Wantz及Gilbert等后来者的修补方法,Ger的腹腔镜修补法以及一些不常见的疝修补术铺平了道路。Chevrel(1979)创建了GREPA,这就是后来的欧洲疝学会,后来又和美国疝学会一起创建了《Hernia》杂志。Nilsson(1993)制定了全国性疝登记制度,致力于更低的复发率和更好的前瞻性研究。在21世纪,Lichtenstein疝修补术逐渐占据主流地位。疝学者接受了系统性结缔组织疾病是腹部疝和盆底脱垂的原因。这种病因可以解释为什么植入物推迟了复发但并没有根除复发。更好的解决方法还有待研究和应用。 | Read R C | 2010 | 中国实用外科杂志2010，30，7： | 13 |
| 7 | 美洲板栗愈伤组织诱导和植株再生的研究(英文)显示文摘在培养基中添加不同植物生长调节剂(生长素和细胞机动素),对美洲板粟愈伤组织的诱导以及植株再生进行了研究。将试管繁殖的小植株切为长0.5cm的小段作为外植体材料,以木本植物培养基加上3%的蔗糖和0.7%的琼脂作为基本培养基,再加上不同浓度的生长素或细胞机动素作为试验处理。生长素包括IBA,NAA,2,4-D和2,4,5-T;细胞机动素包括kinetin,CPPU,thidiazuron(TDZ)和zeatin。结果表明:外植体的植株再生和愈伤组织诱导百分率以及再生植株的形态发生以及愈伤组织的诱导量在不同的植物生长调节剂处理间和同一植物生长调节剂不同浓度的处理间都存在着显著的差异。促使外植体植株再生百分率最高的细胞机动素为TDZ,其次为CPPU,kinitin和zeatin;促使外植体愈伤组织诱导百分率最好的生长素为2,4,5-T,其次为2,4-D,IBA和NAA. | 杨国臣 鲁重格 Theophilus M. Asante Paul E. Read | 2008 | 吉林农业大学学报2008，30，4： | 5 |
| 8 | 乙型肝炎疫苗和HBV感染诱导HBV特异性NK细胞记忆功能显示文摘【据Gut 2021年2月报道】题:乙型肝炎疫苗和HBV感染诱导HBV特异性NK细胞记忆功能(作者Wijaya RS等)接种乙型肝炎疫苗可通过免疫记忆保护机体免受后续感染(传统上被认为是适应性免疫系统的领域)。但在小鼠和非人类灵长类动物中发现了抗原特异性记忆自然杀伤细胞(mNK)后,这一观点受到了挑战。 | WIJAYA RS READ SA TRUONG NR 程俊雅 李海军 | 2021 | 临床肝胆病杂志2021，37，12： | 4 |
| 9 | 澳大利亚人乳头状瘤病毒疫苗计划实施5年对年轻人群生殖器疣患病情况的影响:国家调查数据分析显示文摘目的评估2007年中开始的澳大利亚人乳头状瘤病毒(HPV)疫苗计划对生殖器疣患病情况的影响。设计国家调查数据趋势分析。数据来源数据收集于2004--2011年度澳大利亚8所性健康服务机构;其中2所最大的临床中心收集了自我报告的本中心2009年度HPV疫苗现状。研究对象2004--2011年度首次就诊的85770名澳大利亚出生的国民;其中7686(9.0%)名患生殖器疣。主要结局测量比较前疫苗时期(2004—2007年中)和疫苗时期(2007年中-2001年末)不同人群生殖器疣新发病率变化趋势。结果疫苗时期21岁以下和21~30岁女性诊断患有生殖器疣的比例明显下降,发病率分别从2007年度的11.5%和11.3%下降至2011年度的0.85%和3.1%,P均〈0.001。在30岁以上的女性中未发现发病率的明显下降。在21岁以下和21~30岁异性恋男性人群中疫苗时期生殖器疣的发病率较前疫苗时期明显下降,分别由2007年度12.1%和18.2%下降至2011年度2.2%和8.9%,P均〈0.001。30岁以上的异性恋男性人群中发病率无明显下降。2011年235名21岁以下女性在使用HPV疫苗后无新发生殖器疣病例。结论年轻女性生殖器疣发病率的显著下降和2011年度部分年轻女性使用疫苗后的零发病率,说明HPV疫苗获得实验室外的良好功效。异性恋男性生殖器疣发病率的显著下降可能是由于群体免疫所致。 | Hammad Ali,lecturer Basil Donovan, professor HandanWand,senior lecturer Tim R H Read, sexual health physician David G Regan,senior lecturer Andrew E Grulich, professor Christopher K FaMey, professor Rebecca J Guy, associate professor 尹婕(译) 潘凌亚(校) | 2013 | 英国医学杂志中文版2013，16，4： | 4 |
| 10 | 20 years of excavation response studies at AECL’s Underground Research Laboratory显示文摘 | R.S. Read | 2004 | International Journal of Rock Mechanics and Mining Sciences2004，，8： | 4 |
| 11 | Observations of brittle failure around a circular test tunnel显示文摘 | C.D. Martini R.S. Read J.B. Martino | 1997 | International Journal of Rock Mechanics and Mining Sciences1997，，7： | 3 |
| 12 | A Web-based system enabling the integration,analysis,and 3D sub-surface visualization of groundwater monitoring data and geological models显示文摘The 3D Water Chemistry Atlas is an intuitive,open source,Web-based system that enables the three-dimensional(3D)sub-surface visualization of ground water monitoring data,overlaid on the local geological model(formation and aquifer strata).This paper firstly describes the results of evaluating existing virtual globe technologies,which led to the decision to use the Cesium open source WebGL Virtual Globe and Map Engine as the underlying platform.Next it describes the backend database and search,filtering,browse and analysis tools that were developed to enable users to interactively explore the groundwater monitoring data and interpret it spatially and temporally relative to the local geological formations and aquifers via the Cesium interface.The result is an integrated 3D visualization system that enables environmental managers and regulators to assess groundwater conditions,identify inconsistencies in the data,manage impacts and risks and make more informed decisions about coal seam gas extraction,waste water extraction,and water reuse. | Jane Hunter Charles Brooking Lucy Reading Sue Vink | 2016 | International Journal of Digital Earth2016，9，2： | 3 |
| 13 | Evaluation of a Family Systems Intervention for Managing Pediatric Chronic Illness: Mastering Each New Direction ( MEND )显示文摘 | Brian Distelberg Jackie Williams‐Reade Daniel Tapanes Susanne Montgomery Mayuri Pandit | 2014 | Fam. Proc2014，，： | 3 |
| 14 | Two-photon lithography for 3D magnetic nanostructure fabrication显示文摘铁磁性的材料作为在数据存储设备记录媒介许多十年被利用了。到一架二维的飞机的材料的监禁是在完成超离频的记录的一个重要瓶颈密度,和这导致了提议三维(3D ) 利用领域的跑道记忆沿着 nanowires 围繁殖。然而,复杂几何学的磁性的 nanostructures 高度容易正在质问并且不是的 3D 的制造与标准平版印刷术技术完成了。这里,我们表明一条新途径构造 3D 用二光子的平版印刷术和电气化学的免职的联合的复杂几何学的磁性的 nanostructures。磁性被发现是亲密地,与结构,和磁性的成像的 3D 几何学有关,实验提供领域墙在 3D nanostructured 连接卡住的证据。 | Gwilym Williams Matthew Hunt Benedikt Boehm Andrew May Michael Taverne Daniel Ho Sean Giblin Dan Read John Rarity Rolf Allenspach Sam Ladak | 2018 | Nano Research2018，11，2： | 3 |
| 15 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 16 | 碳酸盐岩台地相模式显示文摘不同类型的碳酸盐岩台地相以不同的外形、沉积相以及演化序列为特征。斜坡可能是单斜的,抑或远端变陡,且可能有裙边或鲕粒砂屑浅水滩坝复合体或者骨屑滩。单斜的斜坡向海方向进入较深的水域,没有明显大陆坡折,且缺少深水角砾岩。远端变陡的斜坡可能系低能量环境,且以浪基面下广布的浅水泥质盖层为特征。若在高能环境下,则可能有海岸沙滩沙丘复合体以及广布的骨骸质砂臂盖层。陆坡相可能拥有丰富的陆坡驱动碎屑所致的角砾岩。镶边的大陆架顶部相对平坦,在高能环境下具有明显的坡折。浅水大陆架边端经由该坡折便进入深水域。这类大陆架的大部分区域可能有潮缘相加积,也可能被早期淹没,这取决于海平面的起伏幅度。它们可能是加积的,也可能是过水型的,包含有沟蚀斜坡,陡坎以及高起伏的侵蚀形态。某些大陆架上发育有陆架内盆地,这种盆地控制着储集层和生油层的分布。孤立的台地通常被深水包围,它们可能位于断裂的大陆边缘上或者海底火山之上。绝大多数的台地具有高起伏的镶边边缘。经受过海平面迅速上升期的台地可能在早期就被淹没,它们以抬升的边缘,生长的斑礁或塔礁以及广布的浅海碳酸盐岩或细粒碎屑岩盖层为特征。完全淹没的大陆架发育在大陆架沉没到水体了透光深度的地方,且通常终止了浅水沉积作用,一般只形成半深水相的薄盖层。某些边缘显示有广泛的向盆地下掉的断裂作用,同时伴有碳酸盐岩沉积,或者厚层的进积碎屑岩层序。台地相的类型随沉积作用,盆地沉降或海平面上升的变化而异,并可能形成不同的演化序列。这里所介绍的几种模式看来足以包容绝大多数地质实例。其中一些则拥有较重要的储集岩相。 | J.Fred Read 金福锦 | 1995 | 国外油气勘探1995，7，2： | 3 |
| 17 | Classifier chains for multi-label classification显示文摘 | Jesse Read Bernhard Pfahringer Geoff Holmes Eibe Frank | 2011 | Machine Learning2011，，3： | 2 |
| 18 | BA和激素对‘Bonny Best’试管番茄愈伤组织形态发生的影响显示文摘用’Bonny Best’番茄品种的子叶和下胚轴作为外植体,在MS附加不同水平和比率的BA和2,4—D(或NAA)或IAA的培养基中,愈伤组织形态发生的情况是不同的。MS+BA4.44μM+2,4-D10μM(子叶),MS+BA0.44-4.44μM+2,4-D1—5μM(下胚轴)使外值体产生淡黄色疏松的愈伤组织,而且生长迅速。若2,4-D浓度低于5μM(子叶)或高于5μM(下胚轴)时,外植体形成白色紧密的愈伤组织,而且生长缓慢,固定2,4-D的浓度,BA浓度由高到低,所形成的愈伤组织的结构由紧密向疏松变化。愈伤组织的液体培养中也出现了类似现象。把愈伤组织转移到生茎培养基中,白色紧密的愈伤组织形成茎较为容易,培养21天后,茎的分化即开始。而疏松的愈伤组织的形态发生则经过了黄色疏松、深褐色胶状到白色紧密的变化。茎的分化出现较晚。愈伤组织培养时生长调节剂的水平对茎的分化有着直接的影响。较高水平的BA(22.2—44.4μM)+NAA10-40μM有利于茎的分化。把子叶和下胚轴切段培养在MS+BA22.2-44.4μM+IAA1-5μM的生茎培养基上,24—60天后,70%以上的外植体正常分化并伸长成茎,生枝率每个切段为3—4个。转移到MS培养基上,形成正常的带根幼苗。把下胚轴切段直接培养在没有激素的MS培养基上,三周后,45.8%的下胚轴形成正常幼苗,出枝率为1.0。 | 乐锦华 Paul E Read 杨国臣 | 1990 | 石河子大学学报(自然科学版)1990，，2： | 2 |
| 19 | Changes in adrenal and testicular activity monitored by salivary sampling in males throughout marathon runs显示文摘 | N. J. Cook G. F. Read R. F. Walker B. Harris D. Riad-Fahmy | 1986 | European Journal of Applied Physiology and Occupational Physiology1986，，： | 2 |
| 20 | AES音频数据流之间的异步采样率转换显示文摘数字视频和音频技术的广泛使用和不断革新,推动了音/视频广播(AVB)设备的快速发展。今天的AVB设备需要更高的图像质量、分辨率、更高的带宽和更多的音/视频处理通道,并且需要将从前彼此独立但实际上相互关联的功能(例如HD—SDI、音频多路传输和解复用,以及异步采样率转换(ASRC))组合在一起。 | Gregg C.Hawkes Read Tidwell John F.Snow | 2007 | 世界电子元器件2007，，9： | 2 |
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