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1未破裂颅内动脉瘤患者管理指南美国心脏协会/美国卒中协会针对医疗专业人员的指南显示文摘目的这份更新版指南旨在为未破裂颅内动脉瘤患者的管理提供全面的循证建议。方法写作组采用系统文献回顾(1977年1月至2014年6月),参考同期已发表的循证指南、个人文件和专家意见来总结现有的证据,指出现有知识的差距;如果合适,则根据美国心脏协会( American Heart Association, AHA)标准做出推荐。本指南经过了包括卒中委员会领导层以及AHA科学声明监督委员会在内的广泛同行评议,然后由AHA科学咨询和协调委员会审批通过。结果本指南对未破裂颅内动脉瘤患者的医疗诊治提出了循证建议,涉及临床表现、自然史、流行病学、危险因素、筛查、诊断、影像学以及手术和血管内治疗的转归。B. Gregory Thompson Robert D. Brown Sepideh Amin-Hanjani Joseph P. Broderick Kevin M. Cockroft E. Sander Connolly Gary R. Duckwiler Catherine C. Harris Virginia J. Howard S. Claiborne (Clay) Johnston Philip M. Meyers Andrew Molyneux Christopher S. Ogilvy Andrew J. Ringer James Torner 肖国栋 徐加平 石际俊 尤寿江 张霞 刘慧慧 曹勇军 2015国际脑血管病杂志2015,23,8:127
2中国西部绿色发展概念框架显示文摘综合绿色发展的国际经验,以自然资本、经济资本、社会资本与人力资本四大资本为核心,提出了中国西部地区绿色发展概念框架。中国西部地区绿色发展概念框架是以'发展中促转变,转变中谋发展'的良性循环发展原则为指导原则,分析西部地区社会经济发展及生态环境和自然资源保护两个方面在发展过程中相互促进和制约的关系,并根据西部地区当前经济资本、环境资本、社会资本以及人力资本数量,通过政府适当干预,如区域规划、区内调整,最终实现社会经济与生态环境和自然资源相协调的绿色发展。该框架综合考虑了中国西部在绿色发展道路上特有挑战与机遇,阐明了社会经济发展与资源环境承载力之间的相互作用机制,明确了中国西部地区'生态友好、社会包容和内生增长'的绿色发展目标。最后,本文针对该绿色发展框架提出了中国西部地区绿色发展的政策建议:提出'西部地区绿色发展战略'是当前西部地区绿色发展进程中最为迫切的需求,中央政府应当尽快制定和实施'西部地区绿色发展战略',同时西部地区政府在省级和地方层面将保护中国西部生态环境与区域扶贫开发相结合,加大对以提升西部地区人力资本为目的的各类工程的投入,强化区域绿色基础建设和生态服务供给,缓解西部地区贫困,提升区域绿色发展进程的速度和质量;开展财政体制机制改革,以提高各级财政资金的使用效率;结合各省发展需求与条件实施以生态城市为发展目标的可持续城镇化发展模式,制定差异化的城镇化发展战略;在西部地区重点和限制开发区尤其是贫困集中和区域发展潜力较大地区,鼓励具有区域特色的新型绿色产业的发展。在发展过程中不断加强制度创新以引导长期绿色发展。刘纪远 邓祥征 刘卫东 李海英 Robyn KRUK Derek THOMPSON Peishen WANG Xuemei BAI 2013中国人口·资源与环境2013,23,10:75
3The Open Quantum Materials Database (OQMD): assessing the accuracy of DFT formation energies显示文摘The Open Quantum Materials Database(OQMD)is a high-throughput database currently consisting of nearly 300,000 density functional theory(DFT)total energy calculations of compounds from the Inorganic Crystal Structure Database(ICSD)and decorations of commonly occurring crystal structures.To maximise the impact of these data,the entire database is being made available,without restrictions,at www.oqmd.org/download.In this paper,we outline the structure and contents of the database,and then use it to evaluate the accuracy of the calculations therein by comparing DFT predictions with experimental measurements for the stability of all elemental ground-state structures and 1,670 experimental formation energies of compounds.This represents the largest comparison between DFT and experimental formation energies to date.The apparent mean absolute error between experimental measurements and our calculations is 0.096 eV/atom.In order to estimate how much error to attribute to the DFT calculations,we also examine deviation between different experimental measurements themselves where multiple sources are available,and find a surprisingly large mean absolute error of 0.082 eV/atom.Hence,we suggest that a significant fraction of the error between DFT and experimental formation energies may be attributed to experimental uncertainties.Finally,we evaluate the stability of compounds in the OQMD(including compounds obtained from the ICSD as well as hypothetical structures),which allows us to predict the existence of~3,200 new compounds that have not been experimentally characterised and uncover trends in material discovery,based on historical data available within the ICSD.Scott Kirklin James E Saal Bryce Meredig Alex Thompson Jeff W Doak Muratahan Aykol Stephan Rühl Chris Wolverton 2015npj Computational Materials2015,,1:62
4心肌梗死多维度评估量表的信效度研究显示文摘目的翻译“心肌梗死多维度评估量表”(Myocardial Infarction Dimensional Assessment Scale,MIDAS),评价其效度、信度及文化相关性,提供一种有效评估心肌梗死患者生活质量的中史版问卷。方法应用专家小组评定法进行问卷文化相关性、语言一致性及内容效度的评价。对88例心肌梗死患者应用问卷对其内部一致性、效标关联效度及结构效度进行评价,对其中30例心梗患者在2周内重新应用问卷收集资料,进行重测信度的评价。结果问卷中所有务目均具有较好的文化相关性,其中2个条目被重新修订。中文版“心肌梗死多维度评估量表”具有较好的表面和内容效度,内容效度指数(CVI)为0.94,其内部一致性及重测信度均可接受。问卷7个亚量表的Cronbach'sa为0.73~0.91,重测信度系数为0.74~0.94,总体Cronbach's α为0.93,重测信度系数为0.85。中史版MIDAS中的各亚量表与中文版“36条目简明量表”(ShortForm 36,SF-36)中的相关亚量表具有显著相关性(P〈0.05)。因子分析结果提示中文版MIDAS具有与原英文量表一致的结构效度。结论中文版“心肌梗死多维度评估量表”是一种具有较高效度和信度的疾病专用量表,可为医护人员量化评估心肌梗死患者生活质量提供可靠的依据。王文茹 Violeta Lopez David R Thompson 李小妹 李小霞 刘美丽 高春燕 2006中华护理杂志2006,41,1:38
5心肌梗死患者院外自助式心脏康复的效果研究显示文摘目的本研究旨在观察急性心肌梗死患者进行院外自助式心脏康复的效果。方法便利选取136例首次发作的急性心肌梗死患者作为研究对象,随机分为两组,每组各68例。实验组在研究者督导下进行以运动锻炼、饮食控制、心理调适为主要内容的院外自助式心脏康复;对照组只接受常规指导。分别在患者出院后3周、6周、12周时评价其康复效果。结果实验组患者较对照组而言,焦虑、抑郁和心理健康状况得到明显改善;某些不良生活方式,如吸烟和缺乏运动得到改善;胸部不适得到缓解;门诊就诊率和再入院率明显降低;但两组自尊状况和生活质量没有显著的差异。结论院外自助式心脏康复对于心肌梗死患者的心脏康复能够起到积极的作用。高丽 李峥 David Arthur David Thompson 2008中华护理杂志2008,43,5:33
6中国和澳大利亚宫颈癌患者人乳头状瘤病毒感染及其他危险因素的对比研究显示文摘目的 探讨中国和澳大利亚宫颈癌患者人乳头状瘤病毒 (HPV)感染及其型别分布 ,并比较两组患者其他危险因素和临床病理特征的差异。方法 采用聚合酶链反应方法分别检测 115例中国宫颈癌患者和 79例澳大利亚宫颈癌患者癌组织中HPVDNA ,用测序法和反向核酸杂交法对HPV进行分型。并分析HPV感染与临床病理特征的关系。结果 中国组HPV阳性率为 76 .8% ,澳大利亚组为 89.9% (P =0 .0 17)。两组间HPVl6和 18型阳性率差别无显著意义 (P =0 .80 6 ) ,HPV5 8和 5 9型在中国组比澳大利亚组多见。HPV阳性率与临床分期、肿瘤组织学类型和分级 ,以及淋巴结转移等无关 ,但HPV型别与组织学类型及分级相关。澳大利亚组中晚期及非鳞癌患者较中国组多。两组患者在宫颈涂片普查次数及一些危险因素方面差异有显著意义。结论 澳大利亚组子宫颈癌患者HPV感染率比中国组明显为高 ;在中国组中HPV5 8和 5 9型是并列第 3常见的感染类型 ;HPV18和 5 9型与恶性度高的宫颈癌相关。刘继红 黄欣 廖革望 李俊东 李艳芳 李孟达 Barbara Rose Carol Thompson 2003中华医学杂志2003,83,9:27
7FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle.Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes 2020Data Intelligence2020,2,1:26
8有关交际法的若干误解显示文摘现在无论您所处的教学实际情形如何,交际语言教学法已成为英语教学中占主导地位的理论模式。不少人曾试图对交际法作一全面评定,并澄清它的主要特征(例如 Rich-ards and Rodgers 198(?) Approaches andM(?)hods in Language Teaching)。在教师培训等场合,人们也普遍认为交际法的原则已经被明确理解和接受(例如 Harmer 1991The Practice of English Language Teach-ing)。Geoff Thompson 刘精忠 1996外语教学理论与实践1996,,4:23
9古里雅冰帽气候环境记录显示文摘古里雅冰帽极低的冰温和冻结到冰床等特征决定了该冰帽贮存了理想的气候环境记录。氧同位素、微粒含量、阴离子、阳离子等参数清楚的年际和季节循环特征,是该冰帽冰芯的高分辨率时间序列的准确断代的基础。冷期时稳定氧同位素值减少、微粒含量和各被测化学元素增加,而暖期时稳定氧同位素值增大、微粒含量和各被测化学元素减少的特征以及各种突发事件记录的合理解释将是系统恢复该冰帽所记录的各种气候环境的钥匙。古里雅冰芯记录表明,80年代中后期在这里发生的气候变暖是过去几十年最强烈的一次。姚檀栋 焦克勤 李忠勤 施维林 李月芳 刘景寿 皇翠兰 谢超 L.G.Thompson E.M. Thompson 1994中国科学(B辑)1994,24,7:23
10利用变形河流阶地限定帕米尔北缘木什背斜的缩短、隆升和侧向扩展显示文摘位于帕米尔前缘逆冲推覆体(Pamir Front Thrust,PFT)东端的木什滑脱背斜,是帕米尔弧形推覆构造带最前缘和最新的变形带。对地形横剖面、纵剖面和水系发育特征的分析表明,木什背斜总体上具有由西向东扩展生长的特征。在背斜核部及北翼发育数级开阔平坦的沿轴向展布的河流阶地,阶地可划分为4期。利用阶地堆积细颗粒石英光释光测年获得阶地面T2a、T3和T4的形成年龄分别为(15.8±2.40)ka、(55.1±10.3)ka、(131.4±23.9)ka。伴随背斜的生长扩展,河流阶地面发生了横向和纵向掀斜,并形成断层陡坎和褶皱陡坎。木什背斜晚第四纪的缩短和隆升主要是通过褶皱翼旋转机制进行的,估算其最小缩短速率为(1.6±0.3)mm/a,最小隆升速率为(1.9±0.3)mm/a。与此同时,沿轴向背斜发生了向东的侧向迁移和旋转。根据背斜垂直隆升与侧向扩展之间的关系,估算背斜在131~16ka期间向东的侧向迁移扩展速率较快,为(14.6±3.6)mm/a;自16ka至今,侧向迁移扩展速率迅速减小至(1.7±0.3)mm/a,背斜向东的迁移扩展可能已基本停止,而以侧向旋转为主。李涛 陈杰 肖伟鹏 Burbank D W 黄明达 Thompson J 2011地震地质2011,33,2:21
11青藏高原冰芯过去100年δ^(18)O记录与温度变化显示文摘以羌塘高原普若岗日冰原钻取的213m冰芯中记录为基础,研究了过去100年来δ18O变化所反映的这一地区的温度变化.结合已获取的青藏高原南部的达索普冰芯、西北部的古里雅冰芯和东北部的敦德冰芯,综合研究了青藏高原温度变化的区域差异.结果表明,青藏高原不同地区冰芯中δ18O变化各有特点,特别是南、北差异和东、西差异十分明显.但4根冰芯记录均反映出过去100年来δ18O增加的趋势,说明过去100年来青藏高原在不断变暖.将δ18O记录所反映的青藏高原温度变化、青藏高原气象记录的温度变化同北半球温度变化比较研究发现,这些记录所反映的过去100年总体变暖趋势是一致的.姚檀栋 郭学军 Lonnie Thompson 段克勤 王宁练 蒲建辰 徐柏青 杨晓新 孙维贞 2006中国科学(D辑)2006,36,1:21
12The Potential Contribution of Subsurface Drip Irrigation to Water-Saving Agriculture in the Western USA显示文摘Water shortages within the western USA are resulting in the adoption of water-saving agricultural practices within this region. Among the many possible methods for saving water in agriculture, the adoption of subsurface drip irrigation (SDI) provides a potential solution to the problem of low water use efficiency. Other advantages of SDI include reduced NO3 leaching compared to surface irrigation, higher yields, a dry soil surface for improved weed control, better crop health, and harvest flexibility for many specialty crops. The use of SDI also allows the virtual elimination of crop water stress, the ability to apply water and nutrients to the most active part of the root zone, protection of drip lines from damage due to cultivation and tillage, and the ability to irrigate with wastewater while preventing human contact. Yet, SDI is used only on a minority of cropland in the arid western USA. Reasons for the limited adoption of SDI include the high initial capital investment required, the need for intensive management, and the urbanization that is rapidly consuming farmland in parts of the western USA. The contributions of SDI to increasing yield, quality, and water use efficiency have been demonstrated. The two major barriers to SDI sustainability in arid regions are economics (i.e., paying for the SDI system), including the high cost of installation; and salt accumulation, which requires periodic leaching, specialized tillage methods, or transplanting of seedlings rather than direct-seeding. We will review advances in irrigation management with SDI.T L Thompson PANG Huan-cheng LI Yu-yi 2009Agricultural Sciences in China2009,8,7:18
13Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ 2006中国神经肿瘤杂志2006,4,1:17
14Acute abdominal obstruction:Colon stent or emergency surgery? An evidence-based review显示文摘According to the American Cancer Society and Colorectal Cancer Statistics 2017,colorectal cancer(CRC) is one of the most common malignancies in the United States and the second leading cause of cancer death in the world in 2018.Previous studies demonstrated that 8%-29% of patients with primary CRC present malignant colonic obstruction(MCO). In the past, emergency surgery has been the primary treatment for MCO, although morbidity and surgical mortality rates are higher in these settings than in elective procedures. In the 1990 s, selfexpanding metal stents appeared and was a watershed in the treatment of patients in gastrointestinal surgical emergencies. The studies led to high expectations because the use of stents could prevent surgical intervention, such as colostomy, leading to lower morbidity and mortality, possibly resulting in higher quality of life. This review was designed to provide present evidence of the indication, technique, outcomes, benefits, and risks of these treatments in acute MCO through the analysis of previously published studies and current guidelines.Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Christopher C Thompson Eduardo Guimaraes Hourneaux de Moura 2019World Journal of Gastrointestinal Endoscopy2019,11,3:15
15Climatic and environmental implications from organic matter in Dasuopu glacier in Xixiabangma in Qinghai-Tibetan Plateau显示文摘A series of organic compounds in snow and ice were identified from Dasuopu glacier in Xixiabangma in Qinghai-Tibetan Plateau. Organic compounds derived from natural organisms include n-alkanes ranging from C15 to C33, normal monoearboxylie acids of C6—C18, n-alkan-2-ones of C24—C31 and esters. The unstable compounds widely present in lower troposphere disppear in the middle-upper troposphere. Lots of other organic compounds from petroleum residues were also unexpectedly identified from the glacier, covering pristane, phytane, extended tricyclie terpanes of C19—C29, C24 tetracyclic terpane, αβ hopane compounds of C27—C35, and cholestanes of C27—C29. The remote Xixiabangma region is unambiguously polluted from anthropology activities. The petroleum residues were proposed to be mainly from the Mideast and India, not from China. The organic pollutants from oil fires ignited during the well-known Gulf War which broke out in 1991 were also recorded in the glacier.谢树成 姚檀栋 康世昌 段克勤 徐柏青 L. G. Thompson 1999Science China Earth Sciences1999,42,4:15
16δ^(18)O record and temperature change over the past 100 years in ice cores on the Tibetan Plateau显示文摘The 213 m ice core from the Puruogangri Ice Field on the Tibetan Plateau facilitates the study of the regional temperature changes with its δ18O record of the past 100 years. Here we combine information from this core with that from the Dasuopu ice core (from the southern Tibetan Plateau), the Guliya ice core (from the northwestern Plateau) and the Dunde ice core (from the northeastern Plateau) to learn about the regional differences in temperature change across the Tibetan Plateau. Theδ18O changes vary with region on the Plateau, the variations being especially large between South and North and between East and West. Moreover, these four ice cores present increasing δ18O trends, indicating warming on the Tibetan Plateau over the past 100 years. A comparative study of Northern Hemisphere (NH) temperature changes, the δ18O-reflected temperature changes on the Plateau, and available meteorological records show consistent trends in overall warming during the past 100 years.Lonnie Thompson 2006Science China Earth Sciences2006,49,1:14
17Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma显示文摘Primary liver cancer is the fifth most common malignan- cy in the world and is a leading cause of cancer-related mortality.Available treatment for hepatocellular carcino- ma(HCC),the commonest primary liver cancer,is rarely curative and there is a need to develop therapy that is more effective.Specific and powerful gene silencing that can be achieved by activating RNA interference(RNAi) has generated enthusiasm for exploiting this pathway for HCC therapy.Many studies have been carried out with the aim of silencing HCC-related cellular oncogenes or the hepatocarcinogenic hepatitis B virus(HBV)and hepatitis C virus(HCV).Proof of principle studies have demonstrated promising results,and an early clinical trial assessing RNAi-based HBV therapy is currently in progress.Although the data augur well,there are several significant hurdles that need to be overcome before the goal of RNAi-based therapy for HCC is realized.Particu- larly important are the efficient and safe delivery of RNAi effecters to target malignant tissue and the limitation of unintended harmful non-specific effects.Patrick Arbuthnot Liam Jed Thompson 2008World Journal of Gastroenterology2008,14,11:14
18No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk显示文摘AIM:To investigate the association of variations in the cyclooxygenase-2(COX2) and uridine diphosphate glucuronosyltransferase 1A6(UGT1A6) genes and non-steroidal anti-inflammatory drugs(NSAIDs) use with risk of colon cancer.METHODS:NSAIDs,which are known to reduce the risk of colon cancer,act directly on COX2 and reduce its activity.Epidemiological studies have associated variations in the COX2 gene with colon cancer risk,but others were unable to replicate this finding.Similarly,enzymes in the UGT1A6 gene have been demonstrated to modify the therapeutic effect of NSAIDs on colon adenomas.Polymorphisms in the UGT1A6 gene have been statistically shown to interact with NSAID intake to influence risk of developing colon adenomas,but not colon cancer.Here we examined the association of tagging single nucleotide polymorphisms(SNPs) in the COX2 and UGT1A6 genes,and their interaction with NSAID consumption,on risk of colon cancer in a population of 422 colon cancer cases and 481 population controls.RESULTS:No SNP in either gene was individually statistically significantly associated with colon cancer,nor did they statistically significantly change the protective effect of NSAID consumption in our sample.Like others,we were unable to replicate the association of variants in the COX2 gene with colon cancer risk(P > 0.05),and we did not observe that these variants modify the protective effect of NSAIDs(P > 0.05).We were able to confirm the lack of association of variants in UGT1A6 with colon cancer risk,although further studies will have to be conducted to confirm the association of these variants with colon adenomas.CONCLUSION:Our study does not support a role of COX2 and UGT1A6 genetic variations in the development of colon cancer.Cheryl L Thompson Sarah J Plummer Alona Merkulova Iona Cheng Thomas C Tucker Graham Casey Li Li 2009World Journal of Gastroenterology2009,15,18:11
19Apoptosis in the pathogenesis and treatment of disease显示文摘Thompson CB 0,,:11
20Process structuring of polymers by solid phase orientation processing显示文摘Solid phase orientation of polymers is one of the most successful routes to enhancement of polymer properties.It unlocks the potential of molecular orientation for the achievement of a range of enhanced physical properties.We provide here an overview of techniques developed in our laboratories for structuring polymers by solid phase orientation processing routes,with a particular focus on die drawing,which have allowed control of significant enhancements of a single property or combinations of properties,including Young's modulus,strength,and density.These have led to notable commercial exploitations,and examples of load bearing low density materials and shape memory materials are discussed.COATES P.D. CATON-ROSE P. WARD I.M. THOMPSON G. 2013Science China Chemistry2013,56,8:11
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