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| 1 | Current knowledge on the laboratory diagnosis of Clostridium difficile infection显示文摘Clostridium difficile (C. difficile) is a spore-forming, toxin-producing, gram-positive anaerobic bacterium that is the principal etiologic agent of antibiotic-associated diarrhea. Infection with C. difficile (CDI) is characterized by diarrhea in clinical syndromes that vary from selflimited to mild or severe. Since its initial recognition as the causative agent of pseudomembranous colitis, C. difficile has spread around the world. CDI is one of the most common healthcare-associated infections and a significant cause of morbidity and mortality among older adult hospitalized patients. Due to extensive antibiotic usage, the number of CDIs has increased. Diagnosis of CDI is often difficult and has a substantial impact on the management of patients with the disease, mainly with regards to antibiotic management. The diagnosis of CDI is primarily based on the clinical signs and symptoms and is only confirmed by laboratory testing. Despite the high burden of CDI and the increasing interest in the disease, episodes of CDI are often misdiagnosed. The reasons for misdiagnosis are the lack of clinical suspicion or the use of inappropriate tests. The proper diagnosis of CDI reduces transmission, prevents inadequate or unnecessary treatments, and assures best antibiotic treatment. We review the options for the laboratory diagnosis of CDI within the settings of the most accepted guidelines for CDI diagnosis, treatment, and prevention of CDI. | Adrián Martínez-Meléndez Adrián Camacho-Ortiz Rayo Morfin-Otero Héctor Jesús Maldonado-Garza Licet Villarreal-Trevino Elvira Garza-González | 2017 | World Journal of Gastroenterology2017，23，9： | 7 |
| 2 | The “Brain Stress Timing” phenomenon and other misinterpretations of randomized clinical trial on aneurysmal subarachnoid hemorrhage显示文摘Clipping and coiling are currently the two alternatives in treatment of ruptured cerebral aneurysms. In spite of some meritorious analysis, further discussion is helpful to understand the actual state of art. Retreatment and rebleeding rates clearly favors clipping, although short-term functional outcome seems to be beneficial for clipping, while this different is not such if we perform the comparison at a longer follow up. Longterm follow ups and cost analysis are mandatory to have a clear view of the current picture in treatment of subarachnoid hemorrhage. Treatment strategy should be made by a multi-disciplinary team in accredited centers with proficient experience in both techniques. | Rafael Martinez-Perez Natalia Rayo Agustin Montivero Jorge Marcelo Mura | 2019 | Neural Regeneration Research2019，14，8： | 5 |
| 3 | Evolutionary efficiency and happiness显示文摘 | Rayo L Becker G | 2007 | Journal of Political Economy2007，115，2： | 1 |
| 4 | Effect of alumina preparation on hydrodemetallization and hydrodesulfurization of Maya crude 显示文摘 | RANA M S ANCHEYTA J RAYO P | 2004 | Catalysis Today2004，98，12： | 1 |
| 5 | Peer Comparisons and Consumer Debt 显示文摘 | Rayo L Becker G S | 2006 | The University of Chicago Law Review2006，73，23： | 1 |
| 6 | Identification of genotype 3 hepatitis E virus (HEV) in serum and fecal samples from pigs in Thailand and Mexico, where genotype 1 and 2 HEV strains are prevalent in the respective human populations显示文摘 | Cooper K Huang F F Batista L Rayo C D Bezanilla J C Toth T E Meng X J | 2005 | J Clinic Microbiol2005，43，4： | 1 |
| 7 | Risk-adapted treatment of a-cute promyelocytic leukemia based on all-trans retinoic acid and an-thracycline with addition of cytarabine in con solidation therapy for high-risk patients:Further improvements in treatment outcome显示文摘 | Sanz MA Montesinos P Rayo′n C | 2010 | {H}Blood2010，，： | 1 |
| 8 | Hydrodesulfurizationand hydrocraeking of Maya crude with P-modified NiMo/A1203catalysts显示文摘 | RAYO P RAMIREZ J TORRES-MANCERA P MARROQUIN G MArrY S K ANCHEYTA J | 2012 | Fuel2012，100，： | 1 |
| 9 | Catalyst deactivation pattern along a residue hydrotreating bench-scale reactor显示文摘 | Torres-Mancera P Rayo P Ancheyta J | 2014 | Catalysis Today2014，，： | 1 |
| 10 | Reactivity versus steric effects in fluorinated ketones as esterase inhibitors: a quantum mechanical and molecular dynamics study 显示文摘 | Rayo J Mufioz L Rosell G | 2010 | J Mol Model2010，16，11： | 1 |
| 11 | Predicting cetane number, kinematic viscosity, density and higher heating value ofbiodiesel from its fatty acid methyl ester composition 显示文摘 | Luis Felipe Ram i rez-Verduzco Javier Esteban Rodr i guez- Rodr i guez Alicia del Rayo Jaramillo-Jacob | 2012 | 91 (1):102-1112012，91，1： | 1 |
| 12 | Risk-adapted treatment of acute promyelocytic leukemia based on aIl-trans retinoic acid and anthracycline with addition of cytarabine in con solidation therapy for high-risk patients : Further improvements in treatment outcome 显示文摘 | Sanz MA Montesinos P Rayo' n C | 2010 | Blood2010，115，： | 1 |
| 13 | Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in the rats显示文摘 | Martz D Rayos G Schielke GP | | 0，，04： | 1 |
| 14 | Word and objects显示文摘 | RAYO A | 2002 | Nous2002，，： | 1 |
| 15 | Ontological commitment显示文摘 | RAYO A | 2007 | Philosophy compass2007，，： | 1 |
| 16 | Olfactory proteins mediating chemical communication in the navel orangeworm moth,Amyelois transitella显示文摘 | Leal WS Ishida Y Pelletier J Xu W Rayo J Xu X Ames JB | | 0，，09： | 1 |
| 17 | Vertebral heman- gioma: 'Cold' vertebrae on bone scintigraphy and fluo- rdeoxy-glucose positron emission tomography显示文摘 | Dominguez M Rayo J Serrano J | 2011 | Indian J Nucl Med2011，26，1： | 1 |
| 18 | Quick freezing of one - cell mouse embryo using ethlene glycol with sucrose 显示文摘 | Rayos AA etal | 1992 | Therio genology1992，37，： | 1 |
| 19 | Predicting cetane number, kinematic viscosity, density and higher heating value of biodiesel from its fatty acid methyl ester composition 显示文摘 | Luis Felipe Ramirez-Verduzco JavierEsteban Rodriguez-Rodriguez Alicia del Rayo Jaramillo-Jacob | 2012 | Original Research2012，91，1： | 1 |
| 20 | Hydrotreating of diluted Maya crude with NiMo/Al2O3-TiO2 catalysts: effect of diluent composition显示文摘 | Rayo P Ancheyta J Ramirez J | 2004 | Catalysis Today2004，98，12： | 1 |
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