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| 1 | Pore throat characteristics of tight sandstone of Yanchang Formation in eastern Gansu,Ordos Basin显示文摘An important factor to evaluate reservoir quality is the pore-throat size.However,the strong heterogeneity makes it difficult to characterize the pore-throat distribution in tight reservoirs.The field emission scanning electron microscope(FESEM),high pressure mercury injection and rate-controlled mercury injection are used to investigate the pore-throat size distribution in tight sandstone reservoirs of Member 7 of the Yanchang Formation in eastern Gansu,Ordos Basin,and studies of the pore throat size controlling on physical property of the tight sandstone reservoirs are also carried out.The result shows that the pore type is mainly dominated by the residual intergranular pore,dissolution pore,micropore and a few micro-fractures;the high-pressure mercury injection experiment indicates that the pore-throat size ranges from 0.0148 μm to 40mm,the pore throat more than 1 mm is less;the ratecontrolled mercury injection experiment reveals that for samples with different physical properties,the pore radius mainly varies from 80 μm to 350 μm;the throat radius exhibits the strong heterogeneity,and is from 0.12 μm to 30μm;the pore-throat size can be effectively characterized by combination of high-pressure and rate-controlled mercury injections,and it varies from 0.0148 μm to 350 μm.The permeability is mainly controlled by the large pore throat(>R_(50))which accounts for a small proportion;in the tight sandstone with the permeability greater than 0.1 mD,the permeability is mainly controlled by the micropore and mesopore;in the tight sandstone with the permeability smaller than 0.1 mD,the permeability is mainly controlled by the nanopore and micropore;the proportion of small pore throat increases with reduction of permeability,it is important that the small pore throat influences the reservoir storage property though its effect on permeability are small. | Hao Wu Chunlin Zhang Youliang Ji Rui'e Liu Shang Cao Sheng Chen Yunzhao Zhang Ye Wang Wei Du Gang Liu | 2018 | Petroleum Research2018，3，1： | 7 |
| 2 | Synergistic antitumor efficiency of docetaxel and curcumin against lung cancer显示文摘Curcumin (淫液) ,主要 polyphenolic curcuminoid,从沉金根茎姜黄 longa 获得了,最近被报导在 vitro 并且在 vivo 有潜在的 antitumor 效果。Docetaxel (文档) 为非小的房间肺癌症的治疗被认为化疗同样首要。这里,我们第一次报导淫液能 synergistically 提高在里面 vitro 并且在对肺癌症的文档的 vivo antitumor 功效。在当前的学习,联合索引(CI ) 在 vitro 并且在 vivo 研究是打算的在里面决定在淫液和文档之间的相互作用。在里面在里面 vitro cytotoxicity 测试,中等效果的分析清楚地在某些集中显示了在淫液和文档之间的一个 synergistic 相互作用。而且,在 vivo,评估进一步在确定的 A549 与由静脉内的交货独自一个的文档相比表明了淫液 + 文档的优异 anticancer 功效移植异种皮移植模型。结果证明淫液 synergistically 在 4 天起始的治疗以后立即增加了文档的功效。另外,淫液和文档的同时的管理几乎没在治疗学的剂量包括骨头髓和肝显示出很少毒性到正常纸巾。因此,在 vitro 并且在 vivo,评估在传统的化疗对肺癌症和淫液的介绍表明了淫液和文档的令人满意的 synergistic antitumor 功效是阻止非小的房间肺癌症的传播的一个很有希望的方法。 | Haitao Yin Rui Guo Yong Xu Yulong Zheng Zhibo Hou Xinzheng Dai Zhengdong Zhang Donghui Zheng Hua'e Xu | 2012 | Acta Biochimica et Biophysica Sinica2012，44，2： | 4 |
| 3 | Tick-borne Pathogens in Shanxi Province, China显示文摘Ticks are recognized as one of the most important vectors that cause diseases in animals and humans,and have significant public health impacts worldwide[1].They have a wide range of hosts among terrestrial vertebrates,including mammals,birds,amphibians.The numerous zoonotic pathogens transmitted by ticks are the causative agents of Lyme disease,rickettsiosis,ehrlichioses,relapsing fever,Q fever,and tularemia.Cases of tick-borne diseases are increasing around the world and some emerging or re-emerging pathogens are being discovered,which pose great challenges for prevention and control. | YANG Xiao Na YANG Hui Jun ZHANG Lin HOU Xue Xia MIAO Guang Qing CAO Hong Bing HAO Rui E HAO Qin | 2021 | Biomedical and Environmental Sciences2021，34，5： | 4 |
| 4 | The Value of Subjective Visual Vertical in Diagnosis of Vestibular Migraine显示文摘Objective To study the value of the subjective visual vertical(SVV)in the diagnosis of vestibular migraine(VM).Methods This study recruited 128 VM patients and 64 age-matched normal subjects.We detected the SVV during the interval between attacks in both groups,in sitting upright,and the head tilted at 45°to the left or right.We then examined the correlation between the SVV results with the vestibular evoked myogenic potential(VEMP)and canal paresis(CP).Results It was found there was a significant difference in SVV at the upright position between VM patients and normal controls(P=0.006)and no significant difference was found at the tilts of 45°to the left or right between the two groups.The SVV results at the upright position were significantly correlated with cervical VEMP(P=0.042)whereas not significantly correlated with CP and VEMP.There existed no significant difference in the conformity to the Müller effect(M effect)between the two groups.ROC analysis exhibited that the sensitivity,specificity of SVVs at the upright were 67.200%and 62.500%respectively.The diagnostic value of SVV at the upright position was significantly higher than that at tilts of 45°to the left and right(P=0.006).Nonetheless the diagnostic accuracy was relatively low.Conclusion Abnormality in SVV possibly stems from the lasting functional disorder of cerebellar or high-level cortical centers in VM patients or is linked to the vestibular compensation.The SVV is of low diagnostic value for VM and the value of SVV in VM warrants further study. | Fei LI Jin XU Gen-ru LI Rui GAO Chen-yong SHANG E TIAN Wei-jia KONG Jian-hua ZHUANG Su-lin ZHANG | 2021 | Current Medical Science2021，41，4： | 3 |
| 5 | Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption显示文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017). | Kun Jia Zongyang Lu Fei Zhou Zhiqi Xiong Rui Zhang Zhiwei Liu Yu'e Ma Lei He Cong Li Zhen Zhu Dejing Pan Zhengxing Lian | 2019 | Protein & Cell2019，10，11： | 3 |
| 6 | The Alzheimer's disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation显示文摘Triggering receptor expressed on myeloid cells-like 2(TREML2)is a newly identified susceptibility gene for Alzheimer's disease(AD).It encodes a microglial inflammation-associated receptor.To date,the potential role of mic roglial TREML2 in neuroinflammation in the context of AD remains unclear.In this study,APP/PS1 mice were used to investigate the dynamic changes of TREML2 levels in brain during AD progression.In addition,lipopolysaccharide(LPS)stimulation of primary microglia as well as a lentivirus-mediated TREML2 overexpression and knockdown were employed to explore the role of TREML2 in neuroinflammation in the context of AD.Our res ults show that TREML2 levels gradually increased in the brains of AP P/PS1 mice during disease progression.LPS stimulation of primary microglia led to the release of inflammato ry cytokines including interleukin-1β,inte rleukin-6,and tumor necrosis factor-a in the culture medium.The LPS-induced mic roglial release of inflammatory cytokines was enhanced by TREML2 overexpression and was attenuated by TREML2 knoc kdown.LPS increased the levels of mic roglial M1-type polarization marker inducible nitric oxide synthase.This effect was enhanced by TREML2 overexpression and ameliorated by TREML2 knockdown.Furthermore,the levels of microglial M2-type polarization markers CD206 and ARG1 in the primary microglia were reduced by TREML2 overexpression and elevated by TREML2 knockdown.LPS stimulation increased the levels of NLRP3 in primary microglia.The LPS-induced increase in NLRP3 was further elevated by TREML2 overexpression and alleviated by TREML2 knockdown.In summary,this study provides the first evidence that TREML2 modulates inflammation by regulating microglial polarization and NLRP3 inflammasome activation.These findings reveal the mechanisms by which TREML2 regulates microglial inflammation and suggest that TREML2 inhibition may represent a novel therapeutic strategy for AD. | Si-Yu Wang Xin-Xin Fu Rui Duan Bin Wei Hai-Ming Cao Yan E Shuai-Yu Chen Ying-Dong Zhang Teng Jiang | 2023 | Neural Regeneration Research2023，18，2： | 2 |
| 7 | Cell aggregation of Pseudomonas aeruginosa strain PAO1 as an energy- dependent stress response during growth with sodium dodecyl sulfate显示文摘 | Klebensberger J Rui O Fritz E | 2006 | Archives of microbiology2006，185，6： | 1 |
| 8 | Ophthalmic impairment or higher-order visual deficit? Posterior cortical atrophy: a case report显示文摘 | Ruis C van den Berg E van Zandvoort MJ | 2012 | Appl Neuropsychol Adult2012，19，： | 1 |
| 9 | Three types of proteinase in squid (Todarodes pacificus) hepatopancreas as studied by using carp myofibrils as substrate显示文摘 | TIAN Yuanyong UMEZAWA E DUAN Rui | 2010 | Fisheries Science2010，76，2： | 1 |
| 10 | Cognitive dysfunction in patients with type 2 diabetes显示文摘 | Reijmer YD van den Berg E Ruis C | 2010 | Diabetes Metab Res Rev2010，26，7： | 1 |
| 11 | Cognitive dysfunction in patients with type 2 diabetes显示文摘 | Reijmer YD van den Berg E Ruis C | 2010 | Diabetes Metab Res Rev2010，26，： | 1 |
| 12 | Network coding protocols for smart grid communications 显示文摘 | Rui Prior Daniel E Lucani Yannick Phulpin | 2014 | IEEE Transactions on Smart Grid2014，5，3： | 1 |
| 13 | Steganalysis with JPEG and Gif images显示文摘 | Du Rui Guthrie L E Buchy Doug | 2004 | Seeurity Steganography and Watermarking of Multimedia Contents Ⅵ SPIE2004，5306，： | 1 |
| 14 | Cogni- tive dysfunction in patients with type 2 diabetes 显示文摘 | Reijmer YD van den Berg E Ruis C | 2010 | Diabetes Metab Res Rev2010，26，7： | 1 |
| 15 | Cadmium(Ⅱ)and zinc(Ⅱ)adsorption by the aquatic moss Fontinalis antipyretica:effect of temperature,pH and water hardness显示文摘 | Rosana Pardo Rui R Boaventur | 2004 | Water Research2004，38，： | 1 |
| 16 | Hereditary protein S deficiency in young adults with arterial occlusive disease显示文摘 | Allaart RC Aronson DC Ruys T Rosendaal FR van Bockel JH Bertina RM Bri(o)t E | 1990 | Thromb Haemost1990，64，： | 1 |
| 17 | Expression and spectroscopic analysis of a mutant hepatitis B virus onco-protein HBx without cysteine residues 显示文摘 | Rui E Moura P R Goncalves K A | 2005 | J Virol Methods2005，126，12： | 1 |
| 18 | Intravenous amiodarone in the trealment of recent-onset atrial fibrillation : results of a randomized, controlled study显示文摘 | Galve E Ruis T Ballester R | 1996 | J Am Coil Cardiol1996，27，： | 1 |
| 19 | Real-time editing and relightingof homogeneous translucent materials显示文摘 | Rui Wang Cheslack-Postava E Wang Rui | 2008 | The Visual Computer2008，7，9： | 1 |
| 20 | A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy 显示文摘 | ] Graham E M Ruis K A Hartman A L | 2008 | Am J Obstetr Gyneco12008，199，6： | 1 |
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