|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A complete sequence and comparative analysis of a SARS-associated virus(Isolate BJ01)显示文摘The genome sequence of the Severe Acute Respiratory Syndrome (SARS)-associated virus provides essential information for the identification of pathogen(s), exploration of etiology and evolution, interpretation of transmission and pathogenesis, development of diagnostics, prevention by future vaccination, and treatment by developing new drugs. We report the complete genome sequence and comparative analysis of an isolate (BJ01) of the coronavirus that has been recognized as a pathogen for SARS. The genome is 29725 nt in size and has 11 ORFs (Open Reading Frames). It is composed of a stable region encoding an RNA-dependent RNA polymerase (composed of 2 ORFs) and a variable region representing 4 CDSs (coding sequences) for viral structural genes (the S, E, M, N proteins) and 5 PUPs (putative uncharacterized proteins). Its gene order is identical to that of other known coronaviruses. The sequence alignment with all known RNA viruses places this virus as a member in the family of Coronaviridae. Thirty putative substitutions have been identified by comparative analysis of the 5 SARS- associated virus genome sequences in GenBank. Fifteen of them lead to possible amino acid changes (non-synonymous mutations) in the proteins. Three amino acid changes, with predicted alteration of physical and chemical features, have been detected in the S protein that is postulated to beinvolved in the immunoreactions between the virus and its host. Two amino acid changes have been detected in the Mprotein, which could be related to viral envelope formation. Phylogenetic analysis suggests the possibility of non-human origin of the SARS-associated viruses but provides noevidence that they are man-made. Further efforts should focus on identifying the etiology of the SARS-associated virus and ruling out conclusively the existence of otherpossible SARS-related pathogen(s). | QIN E'de ZHU Qingyu YU Man FAN Baochang CHANG Guohui SI Bingyin YANG Bao PENG Wenming JIANG Tao LIU Bohua DENG Yongqiang LIU Hong ZHANG Yu WANG Cui LI Yuquan GAN Yonghua LI Xiaoyu L Fushuang TAN Gang CAO Wuchun, YANG Ruifu Institute of Microbiology and Epidemiology, Chinese Academy of Military Medical Sciences, Beijing 100071, China WANG Jian, LI Wei, XU Zuyuan, LI Yan, WU Qingfa, LIN Wei, CHEN Weijun, TANG Lin, DENG Yajun, HAN Yujun, LI Changfeng, LEI Meng, LI Guoqing, LI Wenjie, L Hong, SHI Jianping, TONG Zongzhong, ZHANG Feng, LI Songgang, LIU Bin, LIU Siqi, DONG Wei, WANG Jun, Gane K-S Wong, YU Jun & YANG Huanming* Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101300 National Center for Genome Information, Beijing 101300, China | 2003 | Chinese Science Bulletin2003，48，10： | 121 |
| 2 | Molecular and cellular characterization during chondrogenic differentiation of adipose tissue-derived stromal cells in vitro and cartilage formation in vivo显示文摘 | Lin Y Luo E Chen X Liu L Qiao J Yan Z Li Z Tang W Zheng X Tian W | 2006 | 中国生物学文摘2006，20，5： | 31 |
| 3 | Phylogenetic reconstruction of Chirita and allies (Gesneriaceae) with taxonomic treatments显示文摘Chirita D. Don, a large genus in the subfamily Cyrtandroideae of Gesneriaceae, has been the subject of much debate whether it is a natural group or not. In addition, the highly heterogeneous Chirita has also been very problematic with regard to delimitation and subdivision. Here we used the nrDNA internal transcribed spacer and cpDNA trnL-F for molecular phylogenetic analaysis, combined with morphological data. Our results suggest that Chirita is an artificial, polyphyletic genus. The most important character that defines Chirita, the dorso-ventrally oblique and bilamellar stigma, has evolved convergently in different clades of diandrous Cyrtandroideae. Chirita sensu stricto only includes the species of Chirita sect. Chirita, whereas Chirita sect. Microchirita is an independent clade located at the basal node of the phylogenetic tree. Chirita sect. Liebigia is closely related to Didymocarpus with an entire stigma unlike other species of Chirita. The species of Chirita sect. Gibbosaccus, Chiritopsis, Primulina, and Wentsaiboea form a monophyletic group that is sister to a strongly supported clade comprising four monotypic genera Paralagarosolen, Calcareoboea, Petrocodon, and Tengia. We further analyzed the morphological evolution of Chirita and identified a series of morphological synapomorphies for the monophyletic groups revealed herein, and thereby provide a taxonomic treatment in this study. | Yin-Zheng WANG Ru-Bing MAO Yan LIU Jia-Mei LI Yang DONG Zhen-Yu LI James E SMITH | 2011 | Journal of Systematics and Evolution2011，49，1： | 30 |
| 4 | Relationship of Helicobacterpylori eradication with gastric cancer and gastric mucosal histological changes: a 10-year follow-up study显示文摘 | Zhou Liya Lin Sanren Ding Shigang Huang Xuebiao Jin Zhu Cui Rongli Meng Lingmei Li Yuan Zhang Li Guo Changji Xue Yan Yan Xiu'e Zhang Jing | 2014 | Chinese Medical Journal2014，，8： | 28 |
| 5 | Quantitative Trait Loci Mapping of Maize Yield and Its Components Under Different Water Treatments at Flowering Time显示文摘干旱或水应力是导致玉米(Zea mays L.) 的一个严重农学的问题在全世界的收益损失。与干旱忍耐引起混血儿是为解决这个问题的一条重要途径。然而,更低的效率和引起混血儿的一个更长的时期是传统的繁殖节目的劣势。到传统的繁殖节目的适用的分子的标记技术能改进繁殖干旱容忍的玉米的效率,这通常被认出。在玉米干旱忍耐的研究为使用提供有用信息,为产量和它的部件印射并且标注量的特点 loci (QTL ) 根据一个混合线性模型的原则在现在的学习被执行。221 recombinant Yuyu 22 的生来的线(RIL ) 在浇得好、强调水的条件下面被种。在以前的处理组,植物很好被灌溉,而那些在 flowering 时间在后者处理组被强调。每遗传型的十植物连续不断地被种那是 3.00 m ??? 隤? ???? ? 跧?? 闦?? ? 郦 ?? ? 釧 ? ? 跧? 釧??? 雧???????? 雧? 吗?? | Gui-He Lu Ji-Hua Tang Jian-Bing Yan Xi-Qing Ma Jian-Sheng Li Shao-Jiang Chen Jian-Cang Ma Zhan-Xian Liu Li-Zhu E Yi-Rong Zhang Jing-Rui Dai | 2006 | Journal of Integrative Plant Biology2006，48，10： | 13 |
| 6 | Magnetic response to atmospheric heavy metal pollution recorded by dust-loaded leaves in Shougang industrial area, western Beijing显示文摘Fifty-five evergreen tree's leaves growing less than one year were collected from Shougang industrial area in western suburb of Beijing, including steel plants and its ambient residential areas, recreational parks and farmlands. Rock magnetic properties and heavy metal contents were studied. The results show that the magnetic properties of leaf samples are predominated by low-coercivity magnetite, and both the concentration and grain size of magnetite particles gradually decreased with the distance from the main pollution source increases. Moreover, there is a significant linear relationship between magnetic parameters (the low-field magnetic susceptibility, saturation isothermal remanent magnetization and anhysteretic remanent magnetization) and heavy metals contents (Fe, Pb, V, Cr and Zn) (0.73≤R≤ 0.88). Hence, the magnetic parameters of leaves can serve as a proxy for quick detecting of the recent atmospheric metallic pollution. | HU ShouYun DUAN XueMei SHEN MingJie U BLAHA W ROESLER YAN HaiTao E APPEL V HOFFMANN | 2008 | Chinese Science Bulletin2008，53，10： | 10 |
| 7 | Anti-anxiety effect of Valeriana jatamansi Jones extract via regulation of the hypothalamus-pituitary-adrenal axis显示文摘BACKGROUND:Hypothalamus-pituitary-adrenal (HPA) axis dysfunction has been closely linked to anxiety.Previous studies have shown that Valeriana jatamansi Jones extract exhibits clear anxio-lytic effects, but it is unclear about the mechanism underlying regulation of the HPA axis dysfunction in these anxiolytic effects.OBJECTIVE:To observe the effects of Valeriana jatamansi Jones (Zhizhu Xiang) extract on HPA axis function in a rat model of anxiety, and to compare these effects with positive control estazolam.DESIGN, TIME AND SETTING:Randomized, controlled, animal experiment was performed at Chengdu University of Traditional Chinese Medicine, China, between February and September in 2006.MATERIALS:Estazolam was purchased from Shanghai Jiufu Pharmaceutical, China; Valeriana jatamansi Jones was purchased from the Lotus Pond Market for Chinese Herbal Medicine in Chengdu.It consisted of iridoids and flavonoid components.METHODS:A total of 72 Sprague Dawley rats, aged 2 months, were randomly assigned to 6 groups:low-, medium-, and high-dose Valeriana jatamansi Jones groups intragastrically injected with 0.3, 0.6, and 0.9 g/kg per day Valeriana jatamansi Jones extract, respectively; estazolam group intragastrically injected with 1.5 mg/kg per day estazolam; model and normal groups administered 5 mL physiological saline.Anxiety was established in all groups, except the normal group, through the use of elevated plus-maze test at 7 days following drug administration.MAIN OUTCOME MEASURES:Blood β-endorphin and corticosterone levels were determined using enzyme-linked immunosorbent assay following treatment with Valeriana jatamansi Jones extract.Expressions of HPA axis-related genes were measured by cDNA microarray.RESULTS:Blood β-endorphin and corticosterone levels were significantly greater in the model group than in the normal group.Compared with the model group, levels decreased with Valeriana jatamansi Jones extract or estazolam treatment, particularly in the low-dose Valeriana jatamansi Jones group (P<0.01).cDNA microarray results demonstrated that corticotropin-releasing hormone and Orexin, which are associated with HPA axis function, were differentially expressed; expression increased in the model group, but decreased in rats treated with Valeriana jatamansi Jones extract.CONCLUSION:Valeriana jatamansi Jones extract plays a role in regulating HPA axis function in a rat model of anxiety, and this effect was superior to estazolam. | Zhiyong Yan Tian'e Zhang Ting Xiao Lingzhen Pan Jinzhi Qin Zhanping Zhang Changying Zuo | 2010 | Neural Regeneration Research2010，5，14： | 9 |
| 8 | Impact of CYP3A4*1G Polymorphism on Fentanyl Analgesia Assessed by Analgesia Nociception Index in Chinese Patients Undergoing Hysteroscopy显示文摘Background:The clinical efficacy of fentanyl for pain control differs greatly across individuals.The purpose of this study was to investigate the impact of CYP3A4*1G polymorphism including wild-type homozygote (CYP3A4*1/*1,GG),mutant heterozygote (CYP3A4*1/*1G,GA),and mutant homozygote (CYP3A4*1G/*1G,AA)on fentanyl analgesia in Chinese patients undergoing hysteroscopy by the assessment of analgesia nociception index (ANI). Methods:A total of 200 gynecologic patients scheduled for elective hysteroscopy under general anesthesia at Peking University People's Hospital from May to December in 2017 were enrolled in this study.Venous blood was withdrawn for genotyping of CYP3A4*1G before operation.Fentanyl 1μg/kg was administered preoperatively followed by target-controlled infusion of propofol for induction and maintenance.Intraoperative analgesic efficacy of fentanyl was assessed by ANI monitoring at T0(entering room),T1(cervical dilation), T2(start of cervical aspiration),and T3(end of cervical aspiration)time points.The duration of propofol infusion and total dosage of propofol were recorded as well. Results:The patients were divided into three groups according to CYP3A4*1G polymorphism,including 143 in GG group,47in GA group, and 10 in AA group.There was no significant difference in clinical demographics among three groups.The frequency of CYP3A4*1G variant alleles accounted for 16.8%and the distribution of variant alleles was consistent with Hardy-Weinberg equilibrium.Using a multilevel model,ANI values at T1(63.81±19.61),T2(63.63±17.82),and T3(65.68±17.79)were significantly lower than that at T0 (77.16±12.93)in the study population (F =23.50,P <0.001),suggesting that higher levels of pain at T 1,T2,and T3 than T0.Patients with GG genotype showed significantly lower ANI than those with GA or AA genotypes during hysteroscopy under the same dose of fentanyl. Conclusion:CYP3A4*1G polymorphism associated with the analgesic efficacy of intraoperative fentanyl in the patients undergoing hysteroscopy under general anesthesia. | Qi Yan Yi Su Lan Gao Nan Ding Hong-Ying Zhang Wen E Yue Wang Yi Feng Hai-Yan An | 2018 | Chinese Medical Journal2018，，22： | 8 |
| 9 | Response surface optimization of microwave-assisted extraction for HPLC-fluorescence determination of puerarin and daidzein in Radix Puerariae thomsonii显示文摘Microwave-assisted extraction was optimized with response surface methodology for HPLC-fluorescence determination of puerarin and daidzein in Radix Puerariae thomsonii.The optimized extraction procedure was achieved by soaking the sample with 70% methanol(1∶15,v/v)for 30 min,and then microwave irradiation for 11 min at a power of 600 W.Coupling the extraction process with HPLC-fluorescence presented good recovery,satisfactory precision,and good linear relation.Compared with a method from the Chinese Pharmacopoeia,the proposed method enables higher extraction efficiency and more accurate analytical results.It can be of potential value in quality assessment of Radix Puerariae thomsonii medicinal materials. | Ying-Kun Liu E Yan Han-Ying Zhan Zhi-Qi Zhang | 2011 | Journal of Pharmaceutical Analysis2011，1，1： | 8 |
| 10 | Detecting prostate cancer and prostatic calcifications using advanced magnetic resonance imaging显示文摘前列腺癌症和 prostatic 石灰化在老人有高发生。我们试图在检测前列腺癌症和 prostatic 石灰化调查危险性加权的成像的诊断能力。156 个人的一个全部的数字,与前列腺癌症包括 34 并且 122 在这研究与良性的前列腺被注册。计算断层摄影术,常规磁性的回声成像,散开加权的成像,和危险性加权的成像在所有病人上被执行。112 prostatic 石灰化在 87 个病人被检测。常规磁性的回声成像,明显的散开系数,和在检测前列腺癌症和 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性是计算的。McNemars Chi 平方测试被用来在在这些技术之间的敏感和特性比较差别。结果证明在检测 prostatic 癌症的过滤危险性的阶段图象的敏感和特性比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。另外,在检测 prostatic 石灰化的过滤危险性的阶段图象的敏感和特性比得上计算断层摄影术的并且比常规磁性的回声成像和明显的散开系数的大(P < 0.05 ) 。在前列腺癌症给危险性加权的成像(SWI ) 的高发生反常,我们断定危险性加权的成像在检测前列腺癌症比常规磁性的回声成像,散开加权的成像,和计算断层摄影术更敏感、特定。而且,危险性加权的成像能识别类似于计算断层摄影术的 prostatic 石灰化,并且它比常规磁性的回声成像和散开加权的成像好一些。 | Shewei Dou Yan Bai Ankit Shandil Degang Ding Dapeng Shi E Mark Haacke Meiyun Wang | 2017 | Asian Journal of Andrology2017，19，4： | 7 |
| 11 | Mass change study on Arctic glacier Pedersenbreen, during 1936-1990-2009显示文摘Pedersenbreen is a small polythermal valley glacier, located in Svalbard, which has been one of the two glaciers monitored by Chinese Arctic expedition members since 2004. This study estimates its area and volume and analyzes its change during 1936-1990-2009, using field collected GPS/GPR data in 2009 and historical topographic maps published by the Norwegian Polar Institute. We have found that Pedersenbreen is just like many other valley glaciers in Svalbard, having experienced a significant recession since the end of Little Ice Age in the early 20th century. The glacier tongue has retreated more than 0.6 km, while ice volume has decreased by approximately 13%. The overall thinning rate of Pedersenbreen has shown acceleration during the recent decades. Further analysis shows that the ice tongue in the downstream area of Pedersenbreen is melting at the highest rate, while a simultaneous accumulation occurred in the upstream. However, as global temperatures increase, the accumulation area is reducing year by year. | AI SongTao WANG ZeMin TAN Zhi E DongChen YAN Ming | 2013 | Chinese Science Bulletin2013，58，25： | 5 |
| 12 | Diabetes mellitus increases risk for colorectal adenomas in younger patients显示文摘AIM:To determine if diabetes mellitus(DM)is associated with increased risk of colorectal adenomas in younger subjects.METHODS:This was a retrospective cohort study of375 patients undergoing index colonoscopy at a single tertiary care center in the United States.Three cohorts of patients matched for exam date and gender were compared:(1)ages 40-49 years with DM;(2)ages40-49 years without DM;and(3)ages 50-59 years without DM.Data collected included demographics,co-morbidities,colonoscopy and pathology results.Adenoma detection rates(ADR)were calculated and compared.Conditional logistic regression analysis was performed to determine the association between each cohort and ADR.RESULTS:One hundred and twenty-five patients ages40-49 with DM met study eligibility criteria.Patients in the other two cohorts were randomly selected,match-ing for date of exam and gender.ADR was 14.4%in those ages 40-49 years without DM,30.4%in those ages 40-49 years with DM,and 32.0%in those ages50-59 years without DM.Compared to those ages40-49 years without DM,ADR was higher in those ages40-49 years with DM(OR=3.1;95%CI:1.5-6.4;P=0.002)and those ages 50-59 years without DM(OR=2.9;95%CI:1.5-5.6;P=0.002).There was no difference between the ADR in those ages 40-49 years with DM and those ages 50-59 years without DM(P=0.83).CONCLUSION:DM was associated with higher risk of colorectal adenomas in patients ages 40-49 years.These subjects harbored as many adenomas as those at the standard screening age of 50-59 years without DM. | Hongha T Vu Nneka Ufere Yan Yan Jean S Wang Dayna S Early Jill E Elwing | 2014 | World Journal of Gastroenterology2014，20，22： | 5 |
| 13 | Distribution of aluminum species and the characteristics of structure of poly-aluminum-chloride-sulfate(PACS)显示文摘A series of poly\|aluminum\|chloride\|sulfate (PACS), which has different basicities (γ) and Al 3+ /SO 2- 4 molar ratio, has been prepared and dried at 105℃ and 65℃, respectively. The distribution of aluminum species of PACS was examined, and the effect of γ value, Al 3+ /SO 2- 4 molar ratio, dilution on the distribution of aluminum species of PACS was also investigated by using Al\|ferron timed complex colorimetric method. The IR spectroscopy and X \|ray diffraction were used to study the effect of γ value, Al 3+ /SO 2- 4 molar ratio and the drying temperature on the structure of PACS. The experimental results show that Al 3+ /SO 2- 4 molar ratio has a great effect on the distribution of aluminum species, but the dilution has a little effect on the distribution of aluminum species. The lower the Al 3+ /SO 2- 4 molar ratio, the higher the proportions of the polymer and colloidal species in PACS. The polymeric degree of PACS was related to γ value and Al 3+ /SO 2- 4 molar ratio. Drying temperature has an influence on the structure and the solubility of solid PACS products. | GAO Bao\|yu, YUE Qin\|yan, YU Hui, WANG Yan (Department of Environmental Engineering, Shandong University, Jinan\ 250100, China. E\|mail:bygao@sdu.edu.cn) | 2001 | Journal of Environmental Sciences2001，13，1： | 5 |
| 14 | High power and stable P-doped yolk-shell structured Si@C anode simultaneously enhancing conductivity and Li^(+)diffusion kinetics显示文摘Silicon is a low price and high capacity ancxje material for lithium-ion batteries.The yolk-shell structure can effectively accommodate Si expansion to improve stability.However,the limited rate performance of Si anodes can't meet people's growing demand for high power density.Herein,the phosphorus-doped yolk-shell Si@C materials(P-doped Si@C)were prepared through carbon coating on P-doped Si/SiO_(x)matrix to obtain high power and stable devices.Therefore,the as-prepared P-doped Si@C electrodes delivered a rapid increase in Coulombic efficiency from 74.4%to 99.6%after only 6 cycles,high capacity retention of-95%over 800 cycles at 4 A·g^(-1),and great rate capability(510 mAh·g^(-1)at 35 A·g^(-1)).As a result,P-doped Si@C anodes paired with commercial activated carbon and LiFePO_(4)cathode to assemble lithium-ion capacitor(high power density of〜61,080 W·kg^(-1)at 20 A·g^(-1))and lithium-ion full cell(good rate performance with 68.3 mAh·g^(-1)at 5 C),respectively.This work can provide an effective way tofurther improve power density and stability for energy storage devices. | Ming Chen Qinnan Zhou Jiantao Zai Asma Iqbal TsegayeTadesse Tsega Boxu Dong Xuejiao Liu Yuchi Zhang Changyu Yan Liang Zhao Ali Nazakat SharelPeisan E CheeTongJohn Low Xuefeng Qian | 2021 | Nano Research2021，14，4： | 5 |
| 15 | Genome-wide association mapping of vitamins B1 and B2 in common wheat显示文摘Vitamin B is essential for maintaining normal life activities in humans and animals who have to intake the microelement from the outside, especially from cereal products. In the present study 166 Chinese and foreign wheat cultivars planted in two environments were characterized for variation in vitamin B1 and B2 contents. A genome-wide association study(GWAS) using the wheat 90 K SNP assay identified 17 loci for vitamin B1 and 7 for vitamin B2 contents. Linear regression analysis showed a significantly positive correlation of the number of favorable alleles with vitamin B1 and B2 contents. Marker-trait associations(MTAs) at IWB43809(6AS, 0cM) and IWB69903(6AS, 13cM) were new and stable, and significantly associated with vitamin B1 content across two environments. The loci identified in this study and associated SNP markers could be used for improvement of vitamin B1 and B2 contents to obtain superior quality along with grain yield in wheat. | Jieyun Li Jindong Liu Wei'e Wen Pingzhi Zhang Yingxiu Wan Xianchun Xia Yan Zhang Zhonghu He | 2018 | The Crop Journal2018，6，3： | 4 |
| 16 | Oral microbiota and host innate immune response in bisphosphonate-related osteonecrosis of the jaw显示文摘Bacterial biofilms have emerged as potential critical triggers in the pathogenesis of bisphosphonate(BP)-related osteonecrosis of the jaw(ONJ) or BRONJ. BRONJ lesions have shown to be heavily colonized by oral bacteria, most of these difficult to cultivate and presents many clinical challenges. The purpose of this study was to characterize the bacterial diversity in BRONJ lesions and to determine host immune response. We examined tissue specimens from three cohorts(n530); patients with periodontal disease without a history of BP therapy(Control, n510), patients with periodontal disease having history of BP therapy but without ONJ(BP, n55) and patients with BRONJ(BRONJ, n515). Denaturing gradient gel electrophoresis of polymerase chain reaction(PCR)-amplified 16 S r RNA gene fragments revealed less bacterial diversity in BRONJ than BP and Control cohorts. Sequence analysis detected six phyla with predominant affiliation to Firmicutes in BRONJ(71.6%), BP(70.3%) and Control(59.1%). Significant differences(P,0.05) in genera were observed, between Control/BP, Control/BRONJ and BP/BRONJ cohorts. Enzyme-linked immunosorbent assay(ELISA)results indicated that the levels of myeloperoxidase were significantly lower, whereas interleukin-6 and tumor necrosis factor-alpha levels were moderately elevated in BRONJ patients as compared to Controls. PCR array showed significant changes in BRONJ patients with downregulation of host genes, such as nucleotide-binding oligomerization domain containing protein 2, and cathepsin G, the key modulators for antibacterial response and upregulation of secretory leukocyte protease inhibitor, proteinase 3 and conserved helix–loop–helix ubiquitous kinase. The results suggest that colonization of unique bacterial communities coupled with deficient innate immune response is likely to impact the pathogenesis of ONJ. | Smruti Pushalkar Xin Li Zoya Kurago Lalitha V Ramanathapuram Satoko Matsumura Kenneth E Fleisher Robert Glickman Wenbo Yan Yihong Li Deepak Saxena | 2014 | International Journal of Oral Science2014，6，4： | 4 |
| 17 | Synthesis of methyl methacrylate star-branched polymer with divinylbenzene as a linking agent via controlled/living photopolymerization显示文摘HTEMPO-functionalized central cores were formed with divinylbenzene in ''core first'' method,and the four or five arms star polymers were built via controlled/living free radical photopolymerization.The four arms star polymers were also prepared with controlled/living free radical photopolymerization in ''arm first'' method.The resulting polymers had been confirmed by GPC and 1 H NMR.It showed that the star polymers had low polydispersities and molecular weight(M n) with the 85,000-560,000 g/mol range. | Yan Yan Cui Ya E Ren Xiao Xuan Liu | 2012 | Chinese Chemical Letters2012，23，8： | 3 |
| 18 | CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance显示文摘 | Gaopeng Li Xiaoli Wu Wenchang Qian Huayong Cai Xinbao Sun Weijie Zhang Sheng Tan Zhengsheng Wu Pengxu Qian Keshuo Ding Xuefei Lu Xiao Zhang Hong Yan Haifeng Song Shouhong Guang Qingfa Wu Peter E Lobie Ge Shan Tao Zhu | 2016 | Cell Research2016，26，6： | 3 |
| 19 | Relationship between Earth’s Rotation and Several Strong Earthquakes and Moderate-small Earthquakes Occurring around the Epicenter Regions Prior to Strong Earthquakes显示文摘The relationships between Earth's rotation and the 1975 Haicheng, Liaoning MS7.3 earthquake, 2008 Wenchuan, Sichuan MS8.0 earthquake and the 2004 Sumatra MS9.0 earthquake, as well as moderate-small earthquakes occurring around the epicenter regions prior to them are investigated in this study. The obtained results could benefit the further understanding of the relationship between the Earth's rotation and earthquakes. | Wang Hengxin Zhao Xiaoyan Li Yan'e Chen Xuezhong | 2011 | Earthquake Research in China2011，25，4： | 2 |
| 20 | Study on the Inhibition of Fermented Soybean to Cancer Cells显示文摘In the experiment, the inhibition of isoflavones extracted from soybean and tempe to SP2/0 and Hela cells was studied, and the inhibition rate of each unit for cancer cells was also studied. The results showed that the inhibition rate of tempe isoflavones to SP2/0 was 96.9% and to Hela cells was 69.5% when the concentration was 20 μg· mL-1. In the same condition, the inhibition rate of soybean isoflavones was 83.16% and 60.5%. With the decline of concentration, the inhibition rate decreased. The inhibition of isoflavones to SP2/0 did not exist when the concentration was 5-1.25 μg· mL-1. | LU Yan WANG Wei SHAN Yi E Zhiqiang WANG Liqun | 2009 | Journal of Northeast Agricultural University(English Edition)2009，16，1： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员