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| 1 | 健康素养及运动干预控制糖尿病患者血糖水平的效果评估显示文摘目的评估健康素养及运动干预降低2型糖尿病(T2DM)患者血糖水平的效果。方法以上海市闵行区和长宁区799名最近一次糖化血红蛋白(HbA1c)≥7.5%(或FPG≥10mmol/L)的T2DM患者为研究对象,采用整群随机分组方法分为健康素养干预组、运动干预组、综合干预组(健康素养+运动干预)和对照组,每组各约200人。基线调查、身体测量及生化检测完成后,各干预组分别接受为期1年的干预。第3、6和12个月时,对所有患者进行问卷调查随访、身体测量和HbA1c检测。结果3、6和12个月时患者的总应答率分别为99.4%、98.4%和95.2%。干预满3个月时,综合干预组HbA1c达标率(HbA1c〈7.0%)最高,为25.3%,6和12个月时运动干预组达标率最高,分别为25.3%和34.6%。与基线时相比,各干预组HbA1c值在不同随访时段均有下降,以6个月时最明显,综合干预组平均下降0.48%(95%CI:-0.71%—-0.25%),健康素养干预组下降0.33%(95%a:-0.55%-0.11%),运动干预组下降0.70%(95%CI:-0.92%.0.48%),而对照组略升高0.03%(95%CI:-0.19%~0.25%),差异有统计学意义(P〈0.001)。以对照组为参比,调整可能的混杂因素后,3个月时综合干预组HbA1c效果最佳(β=-0.47,95%CI:-0.73—0.20);随后运动干预的效果逐渐凸现,6和12个月时HbA1c降幅分别达-0.73(95%CI:-0.98—0.47)和-0.75(95%CI:-1.05—-0.45)。分层分析显示,在健康素养较低的患者中3种干预手段均有效,而在算术能力高者中运动干预更为有效。结论健康素养及运动干预均可有效降低上海市社区T2DM患者的HbA1c水平,这将有助于降低患者并发症的发生和早死风险。 | 刘晓娜 夏庆华 方红 李锐 陈英耀 严玉洁 周鹏 姚保栋 姜玉 Russell L Rothman 徐望红 | 2018 | 中华流行病学杂志2018,39,3: | 19 |
| 2 | Household air pollution and lung cancer in China:a review of studies in Xuanwei显示文摘Over half of the world's population is exposed to household air pollution from the burning of solid fuels at home. Household air pollution from solid fuel use is a leading risk factor for global disease and remains a major public health problem, especially in low- and mid-income countries. This is a particularly serious problem in China, where many people in rural areas still use coal for household heating and cooking. This review focuses on several decades of research carried out in Xuanwei County, Yunnan Province, where household coal use is a major source of household air pollution and where studies have linked household air pollution exposure to high rates of lung cancer. We conducted a series of case-control and cohort studies in Xuanwei to characterize the lung cancer risk in this population and the factors associated with it. We found lung cancer risk to vary substantially between different coal types, with a higher risk associated with smoky(i.e., bituminous) coal use compared to smokeless(i.e., anthracite) coal use. The installation of a chimney in homes resulted in a substantial reduction in lung cancer incidence and mortality. Overall, our research underscores the need among existing coal users to improve ventilation, use the least toxic fuel, and eventually move toward the use of cleaner fuels, such as gas and electricity. | Wei Jie Seow Wei Hu Roel Vermeulen H.Dean Hosgood III George S.Downward Robert S.Chapman Xingzhou He Bryan A.Bassig Christopher Kim Cuiju Wen Nathaniel Rothman Qing Lan | 2014 | Chinese Journal of Cancer2014,33,10: | 15 |
| 3 | 健康素养和运动干预对社区2型糖尿病患者医疗不信任的影响研究显示文摘背景医疗不信任可降低患者的医嘱遵从度和服药依从性,影响临床结局,可通过有效的干预得以改善,但相关研究较少。目的评估健康素养干预和运动干预对2型糖尿病(T2DM)患者医疗不信任的影响。方法本研究基于2015年2月至2016年3月开展的一项整群随机对照试验(RCT)。采用多阶段抽样法在上海市闵行区和长宁区各4家社区卫生服务中心的糖尿病管理系统中招募T2DM患者800例,以社区为群随机分入对照组和3个干预组。所有患者接受常规护理,3个干预组在此基础上分别实施基于提高糖尿病教育伙伴关系(PRIDE)工具包的健康素养干预、运动干预、健康素养+运动干预(综合干预)。基线时和干预实施3、6、12个月后及干预结束12个月后对患者开展调查,调查工具包括汉化版健康素养管理表(c-HeLMS)、汉化版糖尿病计算能力测试量表(c-DNT-5)、汉化版医疗不信任指数量表(c-MMI)。采用广义估计方程评估干预效果。结果最终纳入780例患者。c-MMI量表在本人群中具有较好的信度和效度,Cronbach'sα系数为0.826。c-MMI的中位得分为31(7)分,医疗不信任(≥30分)率为65.9%(514/780)。随访期间,四组患者的c-MMI得分及医疗不信任率整体呈下降趋势。与对照组相比,健康素养干预组在3、6个月时医疗不信任风险下降,OR(95%CI)分别为0.42(0.23,0.78)和0.46(0.24,0.88);运动干预组在6、12、24个月时医疗不信任风险下降,OR(95%CI)分别为0.50(0.25,0.99)、0.43(0.22,0.86)、0.37(0.19,0.72);综合干预组在6个月时医疗不信任风险降低,OR(95%CI)为0.30(0.16,0.56)。结论基于PRIDE工具包的健康素养干预和步行运动干预均可有效降低T2DM患者的c-MMI得分,有助于改善患者的医疗不信任。 | 王梦妍 王蕾 陈英耀 方红 夏庆华 Russell L Rothman 徐望红 | 2022 | 中国全科医学2022,25,1: | 15 |
| 4 | 体质指数与非吸烟女性肺癌关系的前瞻性队列研究显示文摘目的:研究体质指数(body mass index,BMI)与非吸烟女性肺癌的关系。方法:建立1997—2000年上海市区74942人(其中非吸烟者72829人)、年龄40~70岁的女性队列,每2年随访1次,至2007年12月共收集271例非吸烟女性肺癌病例。用COX回归模型分析BMI与非吸烟女性肺癌发生的相对危险度(relative risk,RR)和95%可信区间(95%confidence interval,95%CI)。结果:调整年龄、教育程度、绝经状态等因素后,基线BMI、20岁BMI与非吸烟女性肺癌危险均无关。基线BMI最高四分组与最低组比较,RR=0.95(95%CI:0.67~1.34);20岁BMI最高四分组与最低组比较,RR=0.77(95%CI:0.52~1.15)。基线BMI和年龄与非吸烟女性肺癌之间关系的分层分析得到相似结果。结论:40岁以上非吸烟女性的BMI可能与其肺癌发生的危险性没有关联。 | 陈伟 高玉堂 CHOW Wong-ho ROTHMAN Nathaniel 张薇 杨工 SHU Xiao-ou ZHENG Wei 项永兵 | 2009 | 肿瘤2009,29,5: | 6 |
| 5 | 医学专业精神及医疗保密:美国历史及现状中的冲突显示文摘讨论卫生部门宣传和加强强制汇报的法律的努力、强制性汇报的规定与医学专业精神及个人自主性之间的冲突、私人医生避免遵守这些规则的策略、病人和倡议者设法避免强制性登记和检测的策略,以及医生/病人和公共卫生官员达成的妥协。最后对公共卫生政策提出建议,认识到强制性汇报存在的问题和卫生政策透明度的重要性。 | Sheila M. Rothman | 2007 | 医学与哲学(A)2007,28,7: | 3 |
| 6 | A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods显示文摘 | Til Stürmer Manisha Joshi Robert J. Glynn Jerry Avorn Kenneth J. Rothman Sebastian Schneeweiss | 2006 | Journal of Clinical Epidemiology2006,,5: | 2 |
| 7 | Interpreting functional imaging studies in terms of neurotransmitter cycling显示文摘 | Shulman RG Rothman DL | 1998 | Proc Natl Acad Sci USA1998,95,11: | 2 |
| 8 | HITEMP, the high-temperature molecular spectroscopic database显示文摘 | L.S. Rothman I.E. Gordon R.J. Barber H. Dothe R.R. Gamache A. Goldman V.I. Perevalov S.A. Tashkun J. Tennyson | 2010 | Journal of Quantitative Spectroscopy and Radiative Transfer2010,,15: | 2 |
| 9 | Environmental Kuznets curves—real progress or passing the buck?显示文摘 | Dale S Rothman | 1998 | Ecological Economics1998,,2: | 2 |
| 10 | The HITRAN 2008 molecular spectroscopic database显示文摘 | L.S. Rothman I.E. Gordon A. Barbe D.Chris Benner P.F. Bernath M. Birk V. Boudon L.R. Brown A. Campargue J.-P. Champion K. Chance L.H. Coudert V. Dana V.M. Devi S. Fally J.-M. Flaud R.R. Gamache A. Goldman D. Jacquemart I. Kleiner N. Lacome W.J. Lafferty J | 2009 | Journal of Quantitative Spectroscopy and Radiative Transfer2009,,9: | 2 |
| 11 | 协调纸质文件管理与电子信息管理的十条规则显示文摘传统文件管理与电子信息管理之间的内在冲突表现在前者关注其作为历史记录的稳定性 ,后者关注对数据存取的控制。人们开始关注这两个方面 ,力求协调这两者的关系。文章总结了这方面的一些实际经验 。 | David Rothman 王绍侠 | 2002 | 山西档案2002,,3: | 2 |
| 12 | Lattice Boltzmann model of immiscible fluids 显示文摘 | Gunstensen A K Rothman D H Zaleski S | 1991 | Physical Review A1991,43,8: | 1 |
| 13 | The nature of pseudoarthrosis 显示文摘 | Depalma AF Rothman RH | 1992 | Clin Orthop Relat Res1992,,284: | 1 |
| 14 | Medical Professionalism Focusing on the Real Issues显示文摘 | Rothman D J | 2000 | The new England iournal of medicine2000,342,17: | 1 |
| 15 | Analysis of macromolecule resonances in 1H-MR spectra of human brain显示文摘 | Behar KL Rothman DL Spencer DD | 1994 | Magn Reson Med1994,32,3: | 1 |
| 16 | Geostatisticalinversion of 3D seismic data for thin sand delineation显示文摘 | Rothman D H | 1998 | Geophysics1998,51,2: | 1 |
| 17 | Percutaneous coil occlusion of patent ductus arteriosus显示文摘 | Rothman A Lucas VW Sklansky MS Cocalis MW Kashani IA | 1997 | J Pediatr1997,130,3: | 1 |
| 18 | Consistency of standards and stability of pass/fail decisions with examiner-based standard-setting methods in a small-scale objective structured clinical examination显示文摘 | Cusimano MD Rothman AI | 2004 | Acad Med2004,79,10: | 1 |
| 19 | Sickness impact of chronic nonbacterial prostatitis and its correlates 显示文摘 | Wenninger K Heiman J R Rothman I | 1996 | J Urol1996,155,3: | 1 |
| 20 | Throm- bospondin, a potentiator of tumor cell metastasis 显示文摘 | Tuszynski GP Gasic TB Rothman VL | 1987 | Cancer Res1987,47,: | 1 |