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| 1 | The vital threat of an upper gastrointestinal bleeding: Risk factor analysis of 121 consecutive patients显示文摘瞄准:在预言死亡的病人风险由于分析重要性上面胃肠(UGI ) 在今天的治疗学的政体下面流血。方法:从 1998 ~ 2001,有 UGI 流血的诊断的 121 个病人在我们的医院里被对待。基于病人的数据,一回顾多变量数据分析与开始,超过 270 个单个因素被执行。随后,下列潜在的风险因素经历了逻辑回归分析:年龄,性,起始的血红素, coumarines ,肝肝硬化,前凝血酶时间(磅),胃溃疡(小弯曲),十二指肠溃疡(灯泡我们背墙),福雷斯特分类,脉管的树桩, variceal 流血, Mallory-Weiss 症候群, RBC 替换,周期性的流血,保守、外科的治疗。结果:七十男性(58%) 和 51 女性(42%) 有 70 的中部的年龄的病人(变化:21-96 ) 年被对待。他们的在里面医院死亡是 14% 。当(11/91 )12% 在保守治疗以后死于病人时,(6/30 )20% 在经历外科的治疗以后死了。流血的 UGI 由于十二指肠溃疡发生了(n = 36;30%) ,胃溃疡(n = 35;29%) ,食道的静脉曲张病(n = 12;10%) , Mallory-Weiss 症候群(n = 8;7%) ,粘膜的腐蚀损害(n = 20;17%) ,癌症(n = 5;4%) , coagulopathy (n = 4;3%) ,淋巴瘤(n = 2;2%) ,良性瘤(n = 2;2%) 并且未知理智(n = 1;1%) 。所有上述的因素的逻辑回归分析揭示了那肝肝硬化和十二指肠溃疡(灯泡我们背墙) 是为在 UGI 流血以后的一堂致命的功课的联系风险因素。在内视镜检查法以前,仅仅肝肝硬化是一个可估价的风险因素。此后,肝肝硬化,流血溃疡的地点(灯泡我们背墙) 并且病人的性(男性) 具有为有流血溃疡的病人的临床的结果(死亡) 的预示的重要性。结论:在今天的临床的常规使用的最预示的参数不在预言一个病人的重要威胁由流血的 UGI 摆姿势是足够可靠的。在另一方面,肝肝硬化更经常显著地与增加的风险被联系在在以后的十二指肠的墙定位的溃疡流血以后死。 | Peter Schemmer Frank Decker Genevieve Dei-Anane Volkmar Henschel Klaus Buhl Christian Herfarth Stefan Riedl | 2006 | World Journal of Gastroenterology2006，12，22： | 16 |
| 2 | The Formation of Anthocyanic Vacuolar Inclusions in Arabidopsis thaliana and Implications for the Sequestration of Anthocyanin Pigments显示文摘Anthocyanins 是在大多数植物的大中央液泡积累的 flavonoid 颜料。在液泡内, anthocyanins 能被发现一致地分布式或作为 sub-vacuolar 颜料身体的部分, Anthocyanic Vacuolar 包括(AVI ) 。用作为一个模型在 anthocyanin 引入的条件下面变得理解 AVI 怎么被形成的 Arabidopsis 幼苗,我们这里证明 AVI 的累积强烈与 cyanidin 3 配糖物(C3G ) 和衍生物的形成相关。在 5-O 位置(5gt 异种) 失败到 glycosylate anthocyanidins 的 Arabidopsis 异种积累 AVI 在几乎子叶的每个表皮的房间作为与野类型的幼苗相比,在的地方仅仅房间表演 AVI 的小部分。当幼苗与 vanadate 被对待时,类似的现象被观察。在 AVI 的形成为 autophagy 加亮一个角色,我们证明防碍 autophagic 过程(atg 异种) 的各种各样的异种显示 AVI 的更低的数字,除了 anthocyanins 的减少的累积。有趣地, vanadate 在 atg 异种增加 AVI 的数字,建议几条小径可能参予 AVI 形成。一起拿,我们的结果为能够积累 anthocyanin 颜料的 sub-vacuolar 分隔空间的形成建议新奇机制。 | Lucille Pourcel Niloufer G. Irani Yuhua LU Ken Riedl Steve Schwartz Erich Grotewold | 2010 | Molecular Plant2010，3，1： | 14 |
| 3 | Visualization of geologic geospatial datasets through X3D in the frame of WebGIS显示文摘3D geo spatial data have become the normal.However,to view the data,usually expert software is required,which have up to now hindered the wide spread use of 3D scenes for the display of geological data.The internet real time 3D rendering framework X3D is assessed regarding its suitability for building a geological GIS on the internet.Especially important for geological data,3D rendering enhances the intuitive grasp of the data and enables the user to interactively explore it.It is often necessary to find a solution to distribute this data to a wide range of interested parties,experts and non-experts alike.According to the nature of 3D data,the best technique to display geo-data,the modeling of objects and unresolved issues have to be taken into consideration.The internet is the apparent tool for the public distribution and visualization of 3D data and it was found that through the open ISO-standardized format X3D it offers a multitude of possibilities.A 3D geological interactive map was created with these prerequisites to identify challenges and possibilities through this process.It was found that the use of lead to satisfactory results,that could probably not have been achieved with another technology. | Frederik von Reumont Jamal Jokar Arsanjani Andreas Riedl | 2013 | International Journal of Digital Earth2013，6，5： | 4 |
| 4 | Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist显示文摘Blockade of the interaction of anaphylatoxin C5a with its receptor C5aR1 has been actively studied as a potential treatment for many inflammatory diseases;but current C5a antagonists exhibit inadequate potency and poor species cross-reactivity, and novel biochemical tools are needed to investigate whether the core region of C5a contains important interaction epitopes that can explain these limitations. Herein, we report the development of chimeric protein C5a probes containing both the complete core region of rat or human C5a, and the small-molecule antagonist PMX53-1. These probes were chemically synthesized through hydrazide-based native chemical ligation of a linear peptide hydrazide with the requisite cyclopeptidic antagonist, both of which were made by solid-phase synthesis. Quasi-racemic X-ray crystallography established that attachment of PMX53-1 did not affect the structure of the core region of C5a. Subsequent C5aR1 activity assays demonstrated the probes can provide valuable insights into the development of C5a antagonists;for example, they exhibited significantly better binding affinity and much improved species cross-reactivity than PMX53-1, supporting the notion that the effect of some epitopes outside the C-terminus of C5a should be taken into consideration when designing better C5a antagonists. Surprisingly, the core region of C5a was found to partially agonize C5aR1, suggesting the presence of more than one agonistic interaction in the binding of C5a to C5aR1. This study exemplifies the value of chemical protein synthesis in developing novel receptor probes for drug discovery research. | Chao Zuo Wei-Wei Shi Xiao-Xu Chen Marie Glatz Bernd Riedl Ingo Flamme Elisabeth Pook Jiawei Wang Ge-Min Fang Donald Bierer Lei Liu | 2019 | Science China Chemistry2019，62，10： | 2 |
| 5 | Quality of Life in GERD Patients: Medical Treatment Versus Antireflux Surgery显示文摘 | Ruxandra Ciovica Michael Gadenst?tter Anton Klingler Wolfgang Lechner Otto Riedl Gerhard P. Schwab | 2006 | Journal of Gastrointestinal Surgery2006，，7： | 2 |
| 6 | Phenol-urea-formaldehyde cocondensed resol resins:their synthesis,curing kinetics,and network properties显示文摘 | Guangbo He Bernard Riedl | 2003 | Polym Sci Part B:Polym Phys2003，41，： | 1 |
| 7 | An empirical analysis of design choices in neighborhood-based collaborative filtering algorithms显示文摘 | Herlocker J Konstan J A Riedl J | 2002 | Information Retrieval2002，5，4： | 1 |
| 8 | Structural basis for the inhibition of caspase-3 by XIAP 显示文摘 | Riedl SJ Renatus M Schwarzenbacher R | 2001 | Cell2001，104，5： | 1 |
| 9 | The mycorrhizal contribution to plant productivity,plant nutrition and soil structure in experimental grassland显示文摘 | VAN DER HEIJDEN M G A STREITWOLF-ENGEL R RIEDL R | 2006 | New Phytologist2006，172，4： | 1 |
| 10 | Does Fairness Prevent Market Clearing? An Experimental Investigation显示文摘 | Fehr E Kirchsteiger G Riedl A | | 0，，02： | 1 |
| 11 | Hyaluronan treatment of interstitial cystitis/painful bladder syndrome 显示文摘 | Riedl C R Engelhardt P F Daha K L | 2008 | Int Urogynecol J Pelvic Floor Dysfunct2008，19，5： | 1 |
| 12 | Lesion miss rates and false-negative rates for 1115consecutive cases of stereotactically guided needle-locatized open breast biopsy, with long-term follow- up 显示文摘 | Riedl CC Pfarl G Memarsadeghi M | 2005 | Radiology2005，237，3： | 1 |
| 13 | Biology of diesel exhaust effects on respiratory function显示文摘 | Diaz-Sanchez D | 2005 | J Allergy Clin Immunol2005，115，： | 1 |
| 14 | Softwood bark pyrolysis oil-PF resols (Part 1 ): Resin synthesis and OSB mechanical properties显示文摘 | Amen-Chen Bernard Riedl Xiang-Ming Wang | 2002 | Holzforschung2002，56，2： | 1 |
| 15 | E-commerce recommendation applications显示文摘 | SCHAFER J B KONSTAN J A RIEDL J | 2001 | Data Mining and Knowledge Discovery2001，5，12： | 1 |
| 16 | Organic/inorganic hybrid composites prepared by polymerization compounding and controlled free radical polymerization 显示文摘 | KASSEH A AIT-KADI A RIEDL B | 2003 | Polymer2003，44，5： | 1 |
| 17 | Softwood bark pyrolysis oil-PF resol (Part Ⅱ):Thermal analysis by DSC and TG显示文摘 | Amen-Chen Bernard Riedl Christian C | 2002 | Holzforschung2002，56，3： | 1 |
| 18 | Electromotive drug administration and hydrodistention for the treatment of interstitial cystitis显示文摘 | Riedl CR Knoll M Plas E | 1998 | J Endourol1998，12，3： | 1 |
| 19 | E-commerce recommendation applications 显示文摘 | Schafer J B Konstan J A Riedl J | 2001 | Data Mining and Knowledge Discovery2001，5，12： | 1 |
| 20 | Carotene and novel apocarotenoid concentrations in orange-fleshed Cucumis melo melons- Determinations of fl-carotene bioaccessibility and bioavailability显示文摘 | Fleshman M K Lester G E Riedl K M | 2011 | Journal of Agrieultural and Food Chemistry2011，59，9： | 1 |
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