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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Light-directed spatially addressable parallel chemical synthesis显示文摘 | Read J L Pirrung M C | 1991 | Science1991，251，： | 1 |
| 3 | Effect of carbon on the electronic conductivity and discharge capacity LiCoPO4显示文摘 | Wolfenstine J Read J Allen J L | 2007 | J Power Sources2007，163，2： | 1 |
| 4 | Severe interstitial pneumonitis associated with docetaxel administration显示文摘 | Read W L Mortimer J E Picus J | 2002 | Cancer2002，94，3： | 1 |
| 5 | Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA:differential circulation in mice and rats and the implication for human gene therapy显示文摘 | Ward C M Read M L Seymour L W | 2001 | Blood2001，97，： | 1 |
| 6 | The nature of the banking relationship: A comparison of the experiences of male and female small business owners 显示文摘 | McKechnie S A Ennew C T Read L H | 1998 | International Small Business Journal1998，16，3： | 1 |
| 7 | A redeseription of Cryptosporidium galli Pavlasek, 1999 (Apicompl- exa: Cryptosporidiidae) from birds 显示文摘 | Ryan U M Xiao L Read C | 2003 | J Parasitol2003，89，： | 1 |
| 8 | Democratizing the Neighbourhood? New Private Housing and Home-Owner Self-Organization in Urban China 显示文摘 | Read Benjamin L | 2003 | The China Journal2003，49，： | 1 |
| 9 | White matter medullary infarcts:acute subcortical infarction in the centrum ovale显示文摘 | Read SJ Pettigrew L Schimmel L | 1998 | Cerebrovasc Dis1998，8，： | 1 |
| 10 | Red blood cells from Alzheimer patients and from normal subjects discerned by cell electrophoresis in an aqueous polymer solution显示文摘 | Walter H Widen KF Read L | 1993 | Biochem Biophys Res Commun1993，194，1： | 1 |
| 11 | An analysis of hip joint loading during walking, running and skiing显示文摘 | Bogert AL Read L Nigg BM | 1999 | Med Sci Sports Exerc1999，31，1： | 1 |
| 12 | Evidence for wavelike energy transfer through quantum coherence in photosynthetic systems显示文摘 | ENGEL S CALHOUN R READ L | 2007 | Nature2007，446，7137： | 1 |
| 13 | Chronic dipeptidyl peptidase-4 inhibition with sitagliptin is associated with sustained protection against ischemic left ventricular dysfunction in a pilot study of patients with type 2 diabetes mellitus and coronary artery disease显示文摘 | McCormick L M Kydd A C Read P A | 2014 | Circ Cardiovasc Imaging2014，7，2： | 1 |
| 14 | Narrow-waveband reflectance rations for remote estimation of nitrogen status in cotton 显示文摘 | Read J J Tarpley L Mckinion J M | 2002 | Journal of Environmental Quality2002，31，： | 1 |
| 15 | Light-directed,spatially addressable parallel chemical synthesis显示文摘 | Fodor S P Read J L Pirrung M C | 1991 | Science1991，251，4995： | 1 |
| 16 | Comparative genomesequencing for discovery of novel polymorphisms in Bacillus anthracis 显示文摘 | Read TD Salzberg SL Pop M Shumway M Umayam L Jiang L Holtzapple E Busch JD Smith KL Schupp JM Solomon D Keim P Fraser CM | 2002 | Science2002，296，5575： | 1 |
| 17 | Routine use of the Confusion Assessment Method for the Intensive Care Unit ( CAM- ICU) by bedside nurses may under diagnose delirium 显示文摘 | Reade MC Eastwood GM Peck L | 2011 | Crit Care Resuscit2011，13，： | 1 |
| 18 | Degradation of IGF-I in the aduh rat gastrointestinal tract is limited by a specific antiserum or the dietary protein casein显示文摘 | XIAN C J SHOUBRIDGE C A READ L C | 1996 | J Endocrinol1996，146，： | 1 |
| 19 | Rapid colorimetric assay for cell viability of cytotoxic and growth inhibitory lymphokines显示文摘 | Green L M Reade J L Ware C F | 1984 | Journal of Immunological Methods1984，70，2： | 1 |
| 20 | Design of Over- moded Interaction Circuit for 1 kW 95 GHz TWT显示文摘 | Kory C L Read M E Ives R L | 2009 | IEEE Trans Electron Devices2009，56，5： | 1 |
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