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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Design of a gridded gun and PPM-focusing structure for a high-power sheet electron beam显示文摘 | Read M E Jabotinski V Miram G | 2005 | IEEE Trans on Plasma Sci2005，33，2： | 1 |
| 3 | Comparative genomesequencing for discovery of novel polymorphisms in Bacillus anthracis 显示文摘 | Read TD Salzberg SL Pop M Shumway M Umayam L Jiang L Holtzapple E Busch JD Smith KL Schupp JM Solomon D Keim P Fraser CM | 2002 | Science2002，296，5575： | 1 |
| 4 | Design of Over- moded Interaction Circuit for 1 kW 95 GHz TWT显示文摘 | Kory C L Read M E Ives R L | 2009 | IEEE Trans Electron Devices2009，56，5： | 1 |
| 5 | 显示文摘 | Read S M Clarke A E Bacic A et aL Requirements for division of generative nucleus in cultured pollen tubes of Nicotiana | 1993 | Protoplasma1993，174，： | 1 |
| 6 | Azalea regeneration fromcallus culture显示文摘 | Economous A S Read P E Spanoudaki M J | 1988 | Acta horticuhurae1988，226，1： | 1 |
| 7 | Using of weakly irregular waveguild theory to calculate eigenfrequeneies, Q value, and RF field functions for gyrotron oscillators显示文摘 | FLIFLET A W READ M E | 1981 | Int J Electronics1981，51，4： | 1 |
| 8 | Optimisation of siRNA-mediated RhoA silencing in neuronal cultures 显示文摘 | Suggate E L Ahmed Z Read M L | 2009 | Mol Cell Neurosci2009，40，4： | 1 |
| 9 | Tissue culture of Chestnuts 显示文摘 | Read P E Hosier M A Yang Q | 1985 | Annual Report of The Northern Nut Growers Association1985，76，： | 1 |
| 10 | Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene 显示文摘 | TASSABEHJI M NEWTON V E READ A P | 1994 | Nature Genetics1994，8，： | 1 |
| 11 | Mutational analysis of cis-acting signal in segment 7 of influenza A virus显示文摘 | Hutchinson E C Curran M D Read E K | 2008 | J Virol2008，82，11： | 1 |
| 12 | Evidence that corticotrophin-releasing hormone modulates myometrial contractility during human pregnancy显示文摘 | Tyson E K Smith R Read M | | 0，，12： | 1 |
| 13 | Design of a gridded gun and PPMfocusing structure for a high-power sheet electron beam显示文摘 | Read M E Jabotinski V Miram G | 2005 | [EEE Trans on Plasma Sci2005，33，2： | 1 |
| 14 | PAL Gene activity and rosmarinic acid production in rosemary genotypes 显示文摘 | Ei-Naggar H M Read P E | 2010 | Journal of herbs spices & medicinal plants2010，16，1： | 1 |
| 15 | Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-Ⅲ) from patienta with AIDS and pre-AIDS显示文摘 | Popovic M Sarngadharan MG Read E | 1984 | Science1984，224，： | 1 |
| 16 | Design of Overmod- edinteraetion Circuit for 1-kW 95-GHz TWT 显示文摘 | Kory C L Read M E Ives R L | 2009 | IEEE Trans Electron Devices2009，56，05： | 1 |
| 17 | Evidence that corticotrophin -releasing hormone modulates myometrial contractility during human pregnancy显示文摘 | Tyson E K Smith R Read M | 2009 | Endocrinology2009，150，12： | 1 |
| 18 | A hypothesis for the development of a defined tissue culture medium of higher plants and micropropa- gation of hazelnuts显示文摘 | NAS M N READ P E | 2004 | Scientia Horticulture2004，101，： | 1 |
| 19 | The kinetics and mechanism of the oxidation of S-methyl-L-cysteine,L-cystine and L-cysteine by potassium ferrate显示文摘 | BEWICK S A GRAVES C R MACPHERSON J M SALAH J C THERIAULT A WYAND A E H | 2000 | Inorganica Chimica Acta2000，303，2： | 1 |
| 20 | Balancing the n-cube: a census of colorings显示文摘 | Palmer E M Read R C Robinson R W | 1992 | Journal of Algebraic Combinatoriea1992，1，3： | 1 |
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