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| 1 | 中国黄土粒度的双峰分布及其古气候意义显示文摘中国黄土的粒度分布由分布峰度较高、分选较好的粗粒组分和分布峰度较低、分选较差的细粒组分叠加组成 ;前者代表了冬季风盛行季节近距离低空搬运的粉尘物质 ,其粒度指示了东亚冬季风所主导的近地面气流的强度 ,它在全样中的含量可能反映了冬季风粉尘的沉积通量 ;细粒组分可能主要为常态存在的、由高空气流搬运的远源粉尘 ,代表了黄土高原原始粉尘的本底 ,它的粒度特征与北太平洋西风带粉尘基本一致 ,可能指示了主要由西风带控制的高空气流的强度。黄土的粒度分布函数可用代表这两个组分分布的两个WEIBULL函数的和函数表示。用实测粒度分布数据对分布函数进行拟合可计算出该分布函数的各参数 。 | 孙东怀 鹿化煜 David Rea 孙有斌 吴胜光 | 2000 | 沉积学报2000，18，3： | 224 |
| 2 | 古环境中沉积物粒度组分分离的数学方法及其应用显示文摘陆相沉积物一般由多个粒度组分叠加组成,根据粒度分布曲线的特征可确定组分数、分布类型以及设定粒度分布函数,用设定的分布函数对实测粒度数据拟合可计算出函数的各参数,并获得各组分的百分比和分布函数,从而从数字特征上分离各组分。对流水和风成沉积物研究表明,河流沉积物由细粉砂级悬移组分和中砂至细砂级跃移组分叠加组成;封闭湖的碎屑沉积物主要是降水形成的地表径流搬运的细粉砂级悬移组分;风成砂由高度分选的近源跃移砂组分与细粒大气背景粉尘叠加组成;黄土由低空近源的悬移粉砂组分与高空运源悬移细粒组分叠加组成;北太平洋粉尘只有高空西风搬运的悬移细粒组分,该组分的粒度在中国沙漠、黄土高原和北太平洋的风成物中表现出一致性和成因上的内在联系,是该系统中高空悬移并分散于大气中的背景粉尘。 | 孙东怀 安芷生 苏瑞侠 吴锡浩 王苏民 孙千里 David Rea Jan Bloemendal | 2001 | 自然科学进展(国家重点实验室通讯)2001，11，3： | 119 |
| 3 | 黄土高原现代天然降尘的组成、通量和磁化率显示文摘黄土高原现代天然降尘的季节性变化研究表明 ,矿物粉尘是天然粉尘的主要组成成分 ,有机质和污染物以夏季粉尘中含量最高。粉尘的磁化率在 80~ 1 50单位之间 ,明显高于冰期黄土 ,指示着间冰期时原始粉尘的磁化率就已受到气候条件的影响。粉尘沉积通量的季节性变化在高原北部较大 ,中部和南部变化较小 ,年累积通量也是北部明显高于基本相当的其它地区。分析粉尘沉积的气候过程认为 ,黄土高原的天然降尘主要表现为常态存在的非尘暴降尘 ,大部分为近距离低空再搬运粉尘 ,其沉积通量与地表的干燥度密切相关 ,部分来自内陆远源沙漠 ,通过高空西风气流转输。冬季风粉尘在大部分黄土高原略高于其它季节粉尘 ,而在西北部显著增高。 | 孙东怀 苏瑞侠 陈发虎 袁宝印 David Rea | 2001 | 地理学报2001，56，2： | 31 |
| 4 | Efficacy of rituximab in gastric diffuse large B cell lymphoma patients显示文摘AIM:To evaluate retrospectively the efficacy of rituximab plus chemotherapy in gastric diffuse large B cell lymphoma(DLBCL).METHODS:Sixty patients(median age:58 years)with histologically confirmed gastric DLBCL treated at four Italian institutions between 2000 and 2007,were included in this analysis.Patients were selected by stage (Ⅰ-Ⅳ,Lugano staging system),European Cooperative Oncology Group performance status(0-2)and treatment strategies.Treatment strategies were chemotherapy alone(group A,n=30)[scheduled as cyclophosphamide,doxorubicin,vincristine and prednisone (CHOP)and CHOP-like],and chemotherapy combined with rituximab(group B,n=30).The primary end point of the study was complete response(CR)rate;the secondary end points were disease-free survival (DFS)at 5 years and overall survival(OS).RESULTS:Median follow-up was 62 mo(range:31102 mo).We observed a significant difference between the two groups(A vs B)in terms of CR[76.6%(23/30) vs 100%,P=0.04)and DFS at 5 years[73.3%(22/30) vs 100%,P=0.03).To date,19 group A(63.3%) patients are alive and 11 have died,while all group B patients are alive.No significant differences in toxicity were observed between the two groups.CONCLUSION:Rituximab in combination with chemotherapy improves CR rate,DFS and OS.Further prospective trials are needed to confirm our results. | Davide Leopardo Giuseppe Di Lorenzo Amalia De Renzo Piera Federico Serena Luponio Carlo Buonerba Elide Matano Gerardina Merola Martina Imbimbo Enzo Montesarchio Antonio Rea Maria Carmela Merola Sabino De Placido Giovannella Palmieri | 2010 | World Journal of Gastroenterology2010，16，20： | 19 |
| 5 | Endoscopic management of esophageal stenosis in children:New and traditional treatments显示文摘Post-esophageal atresia anastomotic strictures and postcorrosive esophagitis are the most frequent types of cicatricial esophageal stricture. Congenital esophageal stenosis has been reported to be a rare but typical disease in children; other pediatric conditions are peptic, eosinophilic esophagitis and dystrophic recessive epidermolysis bullosa strictures. The conservative treatment of esophageal stenosis and strictures(ES) rather than surgery is a well-known strategy for children. Before planning esophageal dilation, the esophageal morphology should be assessed in detail for its length, aspect, number and level, and different conservative strategies should be chosen accordingly. Endoscopic dilators and techniques that involve different adjuvant treatment strategies have been reported and depend on the stricture's etiology, the availability of different tools and the operator's experience and preferences. Balloon and semirigid dilators are the most frequently used tools. No high-quality studies have reported on the differences in the efficacies and rates of complications associated with these two types of dilators. There is no consensus in the literature regarding the frequency of dilations or the diameter that should be achieved. The use of adjuvant treatments has been reported in cases of recalcitrant stenosis or strictures with evidence of dysphagic symptoms. Corticosteroids(either systemically or locally injected), the local application of mitomycin C, diathermy and laser ES sectioning have been reported. Some authors have suggested that stenting can reduce both the number of dilations and the treatment length. In many cases, this strategy is effective when either metallic or plastic stents are utilized. Treatment complications, such esophageal perforations, can be conservatively managed, considering surgery only in cases with severe pleural cavity involvement. In cases of stricture relapse,even if such relapses occur following the execution of well-conducted conservative strategies, surgical stricture resection and anastomosis or esophageal substitution are the only remaining options. | Luigi Dall rsquo Oglio Tamara Caldaro Francesca Foschia Simona Faraci Giovanni Federici di Abriola Francesca Rea Erminia Romeo Filippo Torroni Giulia Angelino Paola De Angelis | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，4： | 16 |
| 6 | Hepatocellular carcinoma:Surgical perspectives beyond the barcelona clinic liver cancer recommendations显示文摘The barcelona clinic liver cancer(BCLC)staging system has been approved as guidance for hepatocellular carcinoma(HCC)treatment guidelines by the main Western clinical liver associations.According to the BCLC classification,only patients with a small single HCC nodule without signs of portal hypertension or hyperbilirubinemia should undergo liver resection.In contrast,patients with intermediate-advanced HCC should be scheduled for palliative therapies,even if the lesion is resectable.Recent studies report good short-term and long-term outcomes in patients with intermediate-advanced HCC treated by liver resection.Therefore,this classification has been criticised because it excludes many patients who could benefit from curative resection.The aim of this review was to evaluate the role of surgery beyond the BCLC recommendations.Safe liver resection can be performed in patients with portal hypertension and well-compensated liver function with a 5-year survival rate of 50%.Surgery also offers good long-term result in selected patients with multiple or large HCCs with a reported 5-year survival rate of over 50%and 40%,respectively.Although macrovascular invasion is associated with a poor prognosis,liver resection provides better long-term results than palliative therapies or best supportive care.Recently,researchers have identified several genes whose altered expression influences the prognosis of patients with HCC.These genes may be useful for classifying the biological behaviour of different tumours.A revision of the BCLC classification should be introduced to provide the best treatment strategy and to ensure the best prognosis in patients with HCC. | Alfredo Guglielmi rea Ruzzenente Simone Conci Alessro Valdegamberi Marco Vitali Francesca Bertuzzo Michela De Angelis Guido Mantovani Calogero Iacono | 2014 | World Journal of Gastroenterology2014，20，24： | 16 |
| 7 | ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients. | Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 7 |
| 8 | Italian survey on non-steroidal anti-inflammatory drugsand gastrointestinal bleeding in children显示文摘AIM: To investigate gastrointestinal complications associated with non-steroidal anti-inflammatory drug(NSAIDs) use in children.METHODS: A retrospective, multicenter study was conducted between January 2005 and January 2013, with the participation of 8 Italian pediatric gastroenterology centers. We collected all the cases of patients who refer to emergency room for suspected gastrointestinal bleeding following NSAIDs consumption, and underwent endoscopic evaluation. Previous medical history, associated risk factors, symptoms and signs at presentation, diagnostic procedures, severity of bleeding and management of gastrointestinal bleeding were collected. In addition, data regarding type of drug used, indication, dose, duration of treatment and prescriber(physician or selfmedication) were examined. RESULTS: Fifty-one patients, including 34 males, were enrolled(median age: 7.8 years). Ibuprofen was the most used NSAID [35/51 patients(68.6%)]. Pain was the most frequent indication for NSAIDs use [29/51 patients(56.9%)]. Seven patients had positive family history of Helicobacter pylori(H. pylori) infection or peptic ulcer, and 12 had associated comorbidities. Twenty-four(47%) out of 51 patients used medication inappropriately. Hematemesis was the most frequent symptom(33.3%). Upper gastrointestinal endoscopy revealed gastric lesions in 32/51(62%) patients, duodenal lesions in 17(33%) and esophageal lesions in 8(15%). In 10/51(19.6%) patients, a diagnosis of H. pylori gastritis was made. Forty-eight(94%) patients underwent medical therapy, with spontaneous bleeding resolution, while in 3/51(6%) patients, an endoscopic hemostasis was needed.CONCLUSION: The data collected in this study confirms that adverse events with the involvement of the gastrointestinal tract secondary to NSAID use are also common in | Sabrina Cardile Massimo Martinelli Arrigo Barabino Paolo Gandullia Salvatore Oliva Giovanni Di Nardo Luigi Dall'Oglio Francesca Rea Gian Luigi de'Angelis Barbara Bizzarri Graziella Guariso Enzo Masci Annamaria Staiano Erasmo Miele Claudio Romano | 2016 | World Journal of Gastroenterology2016，22，5： | 7 |
| 9 | Hepatitis B and C virus reactivation in immunosuppressed patients with inflammatory bowel disease显示文摘In recent years,a number of case reports and clinical studies have highlighted the risk of hepatitis B and C virus reactivation in patients with inflammatory bowel disease who are treated with immunosuppressive drugs.The cases of viral hepatitis reactivation that have been reported are characterized by a wide range of clinical manifestations,from viremia without clinically relevant manifestations to fulminant life-threatening hepatitis.The development and dissemination of biological immunosuppressive drugs have led to a significant increase in the number of reports of interest to physicians in a variety of clinical settings.On this topic,there have been a number of published guidelines and reviews that have collected the available evidence,providing recommendations on prophylactic and therapeutic strategies and methods for monitoring patients at risk.However,it should be noted that,to date,very few clinical studies have been published,and most of the recommendations have been borrowed from otherclinical settings.The published studies are mostly retrospective and are based on very heterogeneous populations,using different therapeutic and prophylactic regimens and obtaining conflicting results.Thus,it seems clear that it is desirable to concentrate our efforts on prospective studies,not conducting further reviews of the literature in the continued absence of new evidence. | Stefano Sansone Maria Guarino Fabiana Castiglione Antonio Rispo Francesco Auriemma Ilaria Loperto Matilde Rea Nicola Caporaso Filomena Morisco | 2014 | World Journal of Gastroenterology2014，20，13： | 6 |
| 10 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 11 | Inferior mesenteric arteriovenous fistula: Case report and world-literature review显示文摘Arteriovenous fistulas between the inferior mesenteric artery and vein are rare, with only 26 primary and secondary cases described in the literature. Secondary fistulas occur following operations of the left hemicolon and manifest as abdominal pain, abdominal mass, gastrointestinal bleeding, colonic ischemia and portal hypertension. Symptom intensities are flow-dependent, and can range from minimal symptoms to severe heart failure due to left to right shunt. Diagnosis is usually established by radiological or intraoperative examination. Treatment options include embolization and/or surgical resection. Therapeutic decisions should be adapted to the unique characteristics of the fistula on an individual basis. A new case of a primary arteriovenous fistula is described and discussed along with a complete review of the literature. The patient in this report presented with signs and symptoms of colonic ischemia without portal hypertension. The optimal treatment for this pa-tient required a combination of embolization and surgical operation. The characteristics of these rare inferior mesenteric arteriovenous fistulas are examined and some considerations concerning diagnostic and therapeutic strategies that should be followed are presented. | Antonios Athanasiou Adamantios Michalinos reas Alexrou Sotirios Georgopoulos Evangelos Felekouras | 2014 | World Journal of Gastroenterology2014，20，25： | 5 |
| 12 | A High-Throughput Phenotyping System Using Machine Vision to Quantify Severity of Grapevine Powdery Mildew显示文摘Powdery mildews present specific challenges to phenotyping systems that are based on imaging.Having previously developed lowthroughput,quantitative microscopy approaches for phenotyping resistance to Erysiphe necator on thousands of grape leaf disk samples for genetic analysis,here we developed automated imaging and analysis methods for E.necator severity on leaf disks.By pairing a 46-megapixel CMOS sensor camera,a long-working distance lens providing 3.5×magnification,X-Y sample positioning,and Z-axis focusing movement,the system captured 78%of the area of a 1-cm diameter leaf disk in 3 to 10 focus-stacked images within 13.5 to 26 seconds.Each image pixel represented 1.44 m2 of the leaf disk.A convolutional neural network(CNN)based on GoogLeNet determined the presence or absence of E.necator hyphae in approximately 800 subimages per leaf disk as an assessment of severity,with a training validation accuracy of 94.3%.For an independent image set the CNN was in agreement with human experts for 89.3%to 91.7%of subimages.This live-imaging approach was nondestructive,and a repeated measures time course of infection showed differentiation among susceptible,moderate,and resistant samples.Processing over one thousand samples per day with good accuracy,the system can assess host resistance,chemical or biological efficacy,or other phenotypic responses of grapevine to E.necator.In addition,new CNNs could be readily developed for phenotyping within diverse pathosystems or for diverse traits amenable to leaf disk assays. | Andrew Bierman Tim LaPlumm Lance Cadle-Davidson David Gadoury Dani Martinez Surya Sapkota Mark Rea | 2019 | Plant Phenomics2019，1，1： | 4 |
| 13 | A Procedure for the Design of Novel Assisting Devices for the Sit-to-Stand显示文摘 | Pierluigi Rea Erika Ottaviano Gianni Castelli | 2013 | Journal of Bionic Engineering2013，10，4： | 4 |
| 14 | New insights for the catalytic oxidation of cyclohexane to K-A oil显示文摘Au-based catalysts have been reported to be active in the cyclohexane oxidation to K-A oil, but they showed some limitiations in terms of productivity, selectivity and required reaction conditions. The possibility to overcome some of these limits has been explored coupling Au with Cu, which can be suitable for undergoing the electron-switch in the initial step of the cyclohexane oxidation. Hence, a bimetallic 2 wt% Au Cu/Al_(2)O_(3) catalyst was tested in the oxidation of cyclohexane, working at mild conditions of 120 ℃ and 4 bar of O_(2). The combination of the catalyst with a very small amount of benzaldehyde used as cheaper and non-toxic radical initiator allowed to obtain a very high productivity of cyclohexanol and cyclohexanone(45 mmol*m L/mgmet*h) with a selectivity of 94%. Moreover, comparing the catalysed reaction with the non-catalysed one, the role of the catalyst has been disclosed. | Alessandro Vomeri Marta Stucchi Alberto Villa Claudio Evangelisti rea Beck Laura Prati | 2022 | Journal of Energy Chemistry2022，31，7： | 4 |
| 15 | 在胰腺的 pseudocyst 的管理的 Miniprobe EUS显示文摘 Pancreatic pseudocysts(PP) arise from trauma and pancreatitis;endoscopic gastro-cyst drainage(EGCD) under endoscopic ultrasonography(EUS) in symptomatic PP is the treatment of choice.Miniprobe EUS(MEUS) allows EGCD in children.We report our experience on MEUS-EGCD in PP,reviewing 13 patients(12 children;male:female = 9:3;mean age:10 years,4 mo;one 27 years,malnourished male Belardinelli-syndrome;PP:10 post-pancreatitis,3 post-traumatic).All patients underwent ultrasonography,computed tomography and magnetic resonance imaging.Conservative treatment was the first option.MEUS EGCD was indicated for retrogastric cysts larger than 5 cm,diameter increase,symptoms or infection.EGCD(stent and/or nasogastrocystic tube) was performed after MEUS(20-MHz-miniprobe) identification of place for diathermy puncture and wire insertion.In 8 cases(61.5%),there was PP disappearance;one,surgical duodenotomy and marsupialization of retro-duodenal PP.In 4 cases(31%),there was successful MEUS-EGCD;stent removal after 3 mo.No complications and no PP relapse in 4 years of mean followup.MEUS EGCD represents an option for PP,allowing a safe and effective procedure. | Paola De Angelis Erminia Romeo Francesca Rea Filippo Torroni Tamara Caldaro Giovanni Federici di Abriola Francesca Foschia Claudia Caloisi Vincenzina Lucidi Luigi Dall’Oglio | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 3 |
| 16 | Functional Design for Customizing Sit-To-Stand Assisting Devices显示文摘 | Pierluigi Rea Erika Ottaviano | 2018 | Journal of Bionic Engineering2018，15，1： | 3 |
| 17 | 胸腺瘤微创切除术的基本原则和标准术语的定义显示文摘根治性手术切除是胸腺瘤的主要治疗手段,手术目的在于完整切除肿瘤及胸腺组织,并且进行彻底的探查排除可能存在的非连续但可切除的病灶。通常主张胸骨劈开的整块切除,R0切除是公认的关乎远期疗效的重要因素。近年随着胸腔镜技术的不断进步,微创手术在胸腺瘤手术中的应用受到了极大地关注,但存在许多值得注意的问题,如何保护膈神经?膈神经切除后是否需要行膈肌折叠术?如何在腔镜下判断是否有上腔静脉和肺静脉的浸润?在微创手术时若切缘很近是否更容易发生胸膜播散?如果一次面对的问题太多,很有可能让微创手术的适用范围又回到从前。如果术后出现不良的结果就更难继续去探索微创技术和如何避免这些问题。多数学者仍对微创手术的结果持谨慎态度,如何确保这些结果与标准开放性手术相当是值得重视的问题。尽管微创手术缩短了住院时间并减轻了患者的疼痛,但与开放手术相比微创手术的肿瘤学优势还没能很好地被报道[1]。只有时间能告诉我们这些微创技术和目前的标准治疗是否相当。虽然有经验的术者采用微创手术可以切除邻近的累及器官,然而在快速拓展微创手术之前必须首先通过直接案例小心评估微创手术的预后结果。普遍认为应避免微创手术切除膈神经和大血管。由于胸腺恶性肿瘤的低发病率特点和微创手术的稀少性特点亟需有共同标准的国际合作。为此国际胸腺肿瘤协作组织(International Thymic Malignancy Interest Group, ITMIG)先由有胸腺瘤微创切除术经验的医生组成初步工作组,在回顾了目前文献中针对胸腺瘤微创切除术的定义、术语和策略后提出了初步建议,由拓展工作组进一步完善后由ITMIG工作组中的更多不同背景的专家进行讨论,最终由ITMIG的成员一致通过。内容涉及胸腺瘤微创手术策略、手术方法的基本概念、基本原则和必须遵守的特定标准等定义。以便在前瞻性的数据库采用连续和系统的方式收集数据来更恰当地评估微创手术。使不同中心之间使用这项技术应用共同的语言,便于中心之间的合作和数据资源共享。 | 付浩 中国胸腺瘤协作组全体成员 Alper Toker Joshua Sonett Marcin Zielinski Federico Rea Victor Tomulescu Frank C.Detterbeck | 2014 | 中国肺癌杂志2014，17，2： | 3 |
| 18 | Late Cenozoic eolian deposition in the North Pacific: Asian drying, Tibetan uplift, and cooling of the northern hemisphere显示文摘 | Rea D K Snoeckx H Joseph L H | 1998 | Paleoceanography1998，3，： | 3 |
| 19 | Fluoroquinolone-based protocols for eradication of Helicobacter pylori显示文摘Helicobacter pylori(H. pylori) is a widespread pathogen infecting about 40% of people living in urban areas and over 90% of people living in the developing regions of the world. H. pylori is well-documented as the main factor in the pathogenesis of peptic ulcer disease, chronic gastritis, and gastric malignancies such as cancer and mucosa-associated lymphoid tissuelymphoma; hence, its eradication is strongly recommended. the Maastricht Ⅳ consensus, which focused on the management of H. pylori infection, set important new strategies in terms of treatment approaches, particularly with regards to first- and second-line treatment protocols and led to improved knowledge and understanding of H. pylori resistance to antibiotics. In recent years, various fluoroquinolone-based protocols, mainly including levofloxacin, have been proposed and effectively tested at all therapeutic lines for H. pylori eradication. the aim of the present paper is to review the scientific literature focused on the use of fluoroquinolones in eradicating H. pylori. | Antonio Rispo Pietro Capone fabiana Castiglione Luigi Pasquale Matilde Rea Nicola Caporaso | 2014 | World Journal of Gastroenterology2014，20，27： | 3 |
| 20 | NSAID use and dementia risk in the Cardiovascular Health Study*: Role of APOE and NSAID type显示文摘 | C A. Szekely J C.S. Breitner A L. Fitzpatrick T D. Rea B M. Psaty L H. Kuller P P. Zandi | 2008 | Neurology2008，，1： | 2 |
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