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| 1 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | hnmobi- lization of candida rugosa lipase on bentonite modified with benzyhriethylammonium chloride 显示文摘 | RAMOS M D GOMEZ G I G GONZALEZ N S | 2014 | Journal of Molecular Catalysis B : Enzymatic2014，，99： | 1 |
| 4 | Evidence in Cerro Pampa volcanic rocks in slab-melting prior to ridge-trench collision in southern South America显示文摘 | KAY S M RAMOS V MARQUEZ M | 1993 | J Geology1993，101，： | 1 |
| 5 | Vertical Vibration of Liquid Drops on Nano- Structured Surfaces 显示文摘 | Ramos S M M | 2008 | Nucllnstr and Meth in Phys Res B2008，266，1213： | 1 |
| 6 | Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex显示文摘 | Weisberg M P Ramos M S | 2001 | Neuropharmacology2001，41，6： | 1 |
| 7 | Matrix metalloproteinase and αvβ3 integrin-dependent vascular smooth cell invasion through a type I collagen lattice 显示文摘 | Kanda S Kuzuya M Ramos MA | 2002 | Arteriosler Thromb Vasc Biol2002，20，： | 1 |
| 8 | Influence of quereetin and rutin on growth and antioxidant defense system of a human hepatoma cell line(HepG2)显示文摘 | Alia M Mateos R Ramos S et a1 | 2006 | Eur J Nutr2006，45，1： | 1 |
| 9 | Comparative ecology of seed mass in Paychotria (Rubiaceae) Within and between species effects of seed mass on early performance显示文摘 | PAZ H MAZER S J MARTINEZ RAMOS M | 2005 | Functional Ecology2005，19，4： | 1 |
| 10 | Comparative structural analysis of et-glucosidase inhibitors on difference species: a computational study 显示文摘 | Narayana Moorthy N S Ramos M J Fernandes P A | 2012 | Arch Pharm (Weinheim)2012，345，4： | 1 |
| 11 | Assessing heavy metal contamination in Sado Estuary sediment:an index analysis approach 显示文摘 | Caeiro S Costa M H Ramos T B et cd | 2005 | Ecological Indicators2005，，5： | 1 |
| 12 | Tactile sen-sors for robotic applications显示文摘 | Girao P S Ramos P M P Postolache O | | 0，，3： | 1 |
| 13 | Quercetin prelects human hep- atoma HepG2 against oxidative stress induced by tea-butyl hydroperoxide 显示文摘 | Alia M Ramos S Mateos R el al | 2006 | Toxicol Appl Pbarmacol2006，212，2： | 1 |
| 14 | Sjogren syndrome associated with hepatitis C virus: a multicenter analysis of 137 cases显示文摘 | Ramos - Casals M Loustaud - Ratti V De Vita S | 2005 | Medicine (Baltimore)2005，84，2： | 1 |
| 15 | 显示文摘 | Ramos de Debiaggi S Campillo J M | 1999 | Journal of Materials Research1999，14，： | 1 |
| 16 | Southern Patagonian Plateau basalts and deformation: Baekarc testimony of ridge collision显示文摘 | Ramos V A Kay S M | 1992 | Tectonophysics1992，205，： | 1 |
| 17 | Social inequality in Pap smear coverage:identifying under-users of cervical cancer screening in Argentina显示文摘 | Arrossi S Ramos S Paolino M | 2008 | Reprod Health Mat2008，16，32： | 1 |
| 18 | High prevalence of antimicrobial-resistant Escherichia coli from animals at slaughter: A food safety risk显示文摘 | Ramos S Silva N Canica M | 2013 | Sci Food Agric2013，93，： | 1 |
| 19 | Antihypertensive activity of milk fermented by Enterococcus faecalis strains isolated from raw milk显示文摘 | MUGUERZA B RAMOS M S(A)NCHEZ E | | 0，，01： | 1 |
| 20 | Randomized trial of non-invasive ventilation combined with exercise training in patients with chronic hypercapnic failure due to Chronic Obstructive Pulmonary Disease显示文摘 | Eduardo Márquez-Martín Francisco Ortega Ruiz Pilar Cejudo Ramos Jose Luis López-Campos Borja Valencia Azcona Emilia Barrot Cortés | 2014 | Respiratory Medicine2014，，： | 1 |
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