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| 1 | A review of the effects of dietary organic acids fed to swine显示文摘Animal production depends on nutrient utilization and if done there is an accelerated momentum towards growth with a low cost to feed ratio Public concern over the consumption of pork with antibiotic residues of the animals fed with antibiotic growth promoters(AGP) has paved the way to use other additives like herbs and their products,probiotics,prebiotics etc.Numerous feed additives are in vogue for achieving this target and one such classical example is the usage of organic acids and their salts.Usage of organic acids was in progress for over four decades.Early weaned piglets are(3-4 weeks age) exposed to stress with a reduced feed intake,little or no weight gain.This post weaning lag period is due to a limited digestive and absorptive capacity due to insufficient production of hydrochloric acid,pancreatic enzymes and sudden changes in feed consistency and intake.Lowering dietary pH by weak organic acids was found to overcome these problems.The main activity of organic acids is associated with a reduction in gastric pH converting the inactive pepsinogen to active pepsin for effective protein hydrolysis.Organic acids are both bacteriostatic and bactericidal.Lactic acid has been reported to reduce gastric pH and delay the multiplication of an enterotoxigenic E.coli.These acids are the intermediary products in Kreb's cycle and thus act as an energy source preventing the tissue breakdown resulting from gluconeogenesis and lipolysis.Excretion of supplemental minerals and nitrogen are minimized with organic acids as these form complexes with minerals and aids for their bio-availability.Short chain fatty cids like acetic,propionic and n-butyric acid produced by microbial fermentation of dietary fibre in the large intestines may increase the proliferation of epithelial cells and have stimulatory effects on both endocrine and exocrine pancreatic secretions in pigs.Organic acids also enhances apparent total tract digestibility and improves growth performance.It is concluded that organic acids and their salts increase the protein utilization especially in weaner pigs and improves production indices. | Mocherla V A N Suiryanrayna J V Ramana | 2016 | Journal of Animal Science and Biotechnology2016，7，1： | 15 |
| 2 | Statistical design and evaluation of a propranolol HCl gastric floating tablet显示文摘The purpose of this research was to apply statistical design for the preparation of a gastric floating tablet(GFT)of propranolol HCl and to investigate the effect of formulation variables on drug release and the buoyancy properties of the delivery system.The contents of polyethylene oxide(PEO)WSR coagulant and sodium bicarbonate were used as independent variables in central composite design of the best formulation.Main effects and interaction terms of the formulation variables were evaluated quantitatively using a mathematical model approach showing that both independent variables have significant effects on floating lag time,%drug release at 1 h(D_(1h))and time required to release 90%of the drug(t_(90)).The desired function was used to optimize the response variables,each with a different target,and the observed responses were in good agreement with the experimental values.FTIR and DSC studies of the statistically optimized formulation revealed there was no chemical interaction between drug and polymer.The statistically optimized formulation released drug according to first order kinetics with a non-Fickian diffusion mechanism.Evaluation of the optimized formulation in vivo in human volunteers showed that the GFT was buoyant in gastric fluid and that its gastric residence time was enhanced in the fed but not the fasted state. | Meka Venkata Srikanth Nali Sreenivasa Rao Songa Ambedkar Sunil Battu Janaki Ram Venkata Ramana Murthy Kolapalli | 2012 | Acta Pharmaceutica Sinica B2012，2，1： | 6 |
| 3 | Silica gel catalyzed α-bromination of ketones using N-bromosuccinimide: An easy and rapid method显示文摘An easy and rapid method for the a-bromination of ketones using N-bromosuccinimide(NBS) catalyzed by silica gel in methanol under reflux conditions was developed. The expected products were formed in excellent isolated yields within a short period of time(5–20 min). Major advantages of the present procedure include use of inexpensive and readily available catalyst, exclusion of pre- and post-chemical treatment of catalyst and use of methanol as solvent instead of ethers and chlorinated solvents. | Bodireddy Mohan Reddy Velpula Venkata Ramana Kumar Nallagondu Chinna Gangi Reddy Siripragada Mahender Raob | 2014 | Chinese Chemical Letters2014，25，1： | 5 |
| 4 | 日粮中添加有机酸对猪消化道的影响(综述)显示文摘动物的生产力取决于它们对养分的利用情况,如果一切顺利,动物就会加速增长,成本饲料比降低。公众担心食用饲喂抗生素生长促进剂的猪会生产出带有抗生素残留的肉,这为使用其他饲料添加剂如中草药及其制品、益生菌和益生元等铺平了道路。有许多饲料添加剂为实现这一目标而大量流行,其中一个经典的案例是有机酸以及有机酸盐的使用。有机酸的使用已经持续了四十多年。早期断奶仔猪(3~4周龄)面临着采食量减少的应激,甚至导致体重几乎无增加。仔猪在断奶后出现的这种生长停滞是由于其消化和吸收能力有限所致,也是盐酸和胰腺酶分泌不足以及日粮一致性和采食量的突然变化带来的结果。研究表明利用弱有机酸来降低日粮pH可以克服这些问题。有机酸的主要活性与降低胃内容物pH有关,其可将胃蛋白酶原转变为具有活性的蛋白酶,以进行有效的蛋白质水解。有机酸既能抑菌又能杀菌。据报道,乳酸可以降低胃内容物的pH,并延缓产肠毒素性大肠杆菌的增殖。这些酸性物质是克雷伯氏菌循环的中间产物,它们作为消化道上皮细胞的能量来源,可以防止糖异生和脂解作用引起的组织降解。有机酸可尽量减少添加的矿物质和氮的排泄量,这是因为有机酸会与矿物质形成复合物,提高它们的生物利用率。大肠中的日粮纤维经微生物发酵会生成乙酸、丙酸和正丁酸等短链脂肪酸,它们能够促进消化道上皮细胞的增殖,且对猪胰腺的内分泌和外分泌产生刺激作用。有机酸还可以提高猪的表观总消化道消化率,并改善动物的生长性能。综上,有机酸及有机酸盐可以提高猪尤其是断奶仔猪的蛋白质利用率,同时提高生产指标。 | 付亚楠(译) 张配配(审) Mocherla V A N Suiryanrayna J V Ramana | 2019 | 国外畜牧学(猪与禽)2019，39，2： | 4 |
| 5 | Effect of Diffuser Vane Shape on the Performance of a Centrifugal Compressor Stage显示文摘The present paper reports the results of experimental investigations on the effect of diffuser vane shape on the performance of a centrifugal compressor stage.These studies were conducted on the chosen stage having a backward curved impeller of 500 mm tip diameter and 24.5 mm width and its design flow coefficient is Фd=0.0535.Three different low solidity diffuser vane shapes namely uncambered aerofoil,constant thickness flat plate and circular arc cambered constant thickness plate were chosen as the variants for diffuser vane shape and all the three shapes have the same thickness to chord ratio(t/c=0.1).Flow coefficient,polytropic efficiency,total head coefficient,power coefficient and static pressure recovery coefficient were chosen as the parameters for evaluating the effect of diffuser vane shape on the stage performance.The results show that there is reasonable improvement in stage efficiency and total head coefficient with the use of the chosen diffuser vane shapes as compared to conventional vaneless diffuser.It is also noticed that the aero foil shaped LSD has shown better performance when compared to flat plate and circular arc profiles.The aerofoil vane shape of the diffuser blade is seen to be tolerant over a considerable range of incidence. | T Ch Siva Reddy GV Ramana Murty MVSSSM Prasad | 2014 | Journal of Thermal Science2014，23，2： | 4 |
| 6 | 基于快速傅立叶变换的二阶可靠度分析方法显示文摘建立了一种基于快速傅立叶变换的二阶可靠度分析方法 .状态函数在利用两点近似技术近似为二阶多项式后 ,进一步变换为统计上独立的中间变量之和 .对于中间变量的线性形式表示的状态函数 ,其概率密度的傅立叶变换是各中间变量的概率密度的傅立叶变换之积 .因此 ,状态函数的概率密度可由其傅立叶变换函数的逆变换求得 .文中的傅立叶变换和相应的逆变换均由高效的快速傅立叶变换技术完成 .该方法可应用于正态和非正态分布问题 .由于在构造二阶近似中采用了近似技术 ,因而具有很好的计算效率 .数值算例验证了该方法的应用、效率和精度 . | 刘书田 Ramana V.Grandhi | 2001 | 固体力学学报2001，22，4： | 4 |
| 7 | Identification of predictive MRI and functional biomarkers in a pediatric piglet traumatic brain injury model显示文摘Traumatic brain injury(TBI) at a young age can lead to the development of long-term functional impairments. Severity of injury is well demonstrated to have a strong influence on the extent of functional impairments;however, identification of specific magnetic resonance imaging(MRI) biomarkers that are most reflective of injury severity and functional prognosis remain elusive. Therefore, the objective of this study was to utilize advanced statistical approaches to identify clinically relevant MRI biomarkers and predict functional outcomes using MRI metrics in a translational large animal piglet TBI model. TBI was induced via controlled cortical impact and multiparametric MRI was performed at 24 hours and 12 weeks post-TBI using T1-weighted, T2-weighted, T2-weighted fluid attenuated inversion recovery, diffusion-weighted imaging, and diffusion tensor imaging. Changes in spatiotemporal gait parameters were also assessed using an automated gait mat at 24 hours and 12 weeks post-TBI. Principal component analysis was performed to determine the MRI metrics and spatiotemporal gait parameters that explain the largest sources of variation within the datasets. We found that linear combinations of lesion size and midline shift acquired using T2-weighted imaging explained most of the variability of the data at both 24 hours and 12 weeks post-TBI. In addition, linear combinations of velocity, cadence, and stride length were found to explain most of the gait data variability at 24 hours and 12 weeks post-TBI. Linear regression analysis was performed to determine if MRI metrics are predictive of changes in gait. We found that both lesion size and midline shift are significantly correlated with decreases in stride and step length. These results from this study provide an important first step at identifying relevant MRI and functional biomarkers that are predictive of functional outcomes in a clinically relevant piglet TBI model. This study was approved by the University of Georgia Institutional Animal Care and Use Committee(AUP: A2015 11-001) on December 22, 2015. | Hongzhi Wang Emily W.Baker Abhyuday Mandal Ramana M.Pidaparti Franklin D.West Holly A.Kinder | 2021 | Neural Regeneration Research2021，16，2： | 4 |
| 8 | Effect of grain size on dielectric and ferroelectric properties of nanostructured Ba_0.8)Sr_(0.2)TiO_(3) ceramics显示文摘Barium strontium titanate( Ba_0.8)Sr_(0.2)TiO_(3),BST)nanocrystalline ceramics have been synthesized by high energy ball milling.As the sintering temperature increases from 1200℃to 1350℃,the average grain size of BST ceramics increases from 86 nm to 123 nm.The X-ray diffraction(XRD)studies show that these ceramics are tetragonal.The phase and grain size of the sintered pellets have been estimated from the XRD patterns,scanning electron microscopy(SEM)and transmission electron microscopy(TEM)images.The effect of grain size on dielectric and ferroelectric properties is studied.The dielectric and piezoelectric parameters are greatly improved at room temperature with increase in grain size.The Curie transition temperature is found to shift slightly towards higher temperatures as the grain increases from 86 nm to 123 nm.The coercive field decreases and the remnant polarization and spontaneous polarization increase as the grain size of BST nano ceramics increases.These ceramics are promising materials for tunable capacitor device applications. | Venkata Ramana MUDINEPALLI Leng FENG Wen-Chin LIN B.S.MURTY | 2015 | Journal of Advanced Ceramics2015，4，1： | 3 |
| 9 | 日粮中添加有机酸对猪消化道的影响(综述)(续2)显示文摘本文是《日粮中添加有机酸对猪消化道的影响(综述)》的第三部分,主要介绍有机酸的使用方法和单体有机酸在动物营养中的应用。 | 付亚楠(译) 夏俊花(审) 何闪(制图表) Mocherla VAN Suiryanrayna J V Ramana | 2019 | 国外畜牧学(猪与禽)2019，39，4： | 3 |
| 10 | OFHC铜高应变率激光冲击微坑的尺寸效应(英文)显示文摘采用高温无氧铜材料,实验研究激光冲击压力作用下铜材料表面微坑的几何特征以及尺寸效应作用规律。通过控制热处理温度与保温时间,在厚度截面方向获得多种不同晶粒粒径的试样,结合2种不同光斑大小的实验,研究激光冲击表面高应变率塑性变形的大小效应作用特征。实验结果表明:在相同激光能量条件下,大光斑冲击产生的微坑深度较大。晶粒粒径对微坑深度有较大的影响,小晶粒条件下,产生的坑深较小;大晶粒条件下,光斑大小与晶粒粒径对于坑深的影响较为显著。 | 胡永祥 李康妹 齐晨洁 姚振强 Ramana V.GRANDHI | 2012 | 中国有色金属学会会刊:英文版2012，22，S2： | 3 |
| 11 | An Ontology Centric Approach for Building Collaborative Tagging-based Systems to Manage Personal Knowledge in KAM显示文摘 | WANG Xiaoyan BAO Tie Y.V. Ramana Reddy LIU Shufen WANG Luyi | 2013 | Chinese Journal of Electronics2013，22，3： | 2 |
| 12 | Democratizing entry: Banking deregulations, financing constraints, and entrepreneurship显示文摘 | William R. Kerr Ramana Nanda | 2009 | Journal of Financial Economics2009，，1： | 2 |
| 13 | Evaluation of interface shear strength of composite liner system and stability analysis for a landfill lining system in Thailand显示文摘 | D.T. Bergado G.V. Ramana H.I. Sia Varun | 2006 | Geotextiles and Geomembranes2006，，6： | 2 |
| 14 | Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal显示文摘 | Antonio Ayala Mario F. Mu?oz Sandro Argüelles Kota V. Ramana | 2014 | Oxidative Medicine and Cellular Longevity2014，，： | 2 |
| 15 | 浸渍硅胶薄层色谱板分离钴和镍及数字图像分析法定量(英文)显示文摘Thin layer chromatography(TLC) of cobalt and nickel has been performed on silica gel layers induced with alkali mediated cellulose extract.A novel combination of 10% aqueous solutions of Tween-20 and potassium thiocyanate in 1∶1(v/v) was identified as the best mobile phase for the selective separation of Co2+from Ni2+on the impregnated Silica Gel G layers.The chromatographic characteristics of the cations were studied and the limits of detection as well as the limits of quantification for Co2+and Ni2+were determined.The quantitative estimation of the cations was achieved from the digital image analysis of respective chromatograms.The proposed quantitative method was successfully applied with 0-0.50% error for the determination of Co2+from Ni2+in spiked samples of bauxite,soil and rock containing common cations such as Al3+,Fe2+,Ti4+,Zn2+,Mn2+,Cu2+,Cr6+,Mg2+,etc.under the optimized chromatographic conditions. | P A MOHAMED NAJAR R G SONALI M T NIMJE K V RAMANA RAO | 2012 | 色谱2012，30，10： | 2 |
| 16 | Regulation of simultaneous hydrogen photoproduction during growth by pH alld glutamate in rhodobacter spharoides显示文摘 | Asikala k Ramana C H V Rao P R | 1995 | In J Hydrogen Energy1995，，20： | 1 |
| 17 | Giant Morgagnian hernia masquerading as pleural effusion 显示文摘 | Kumar RV Ramana DV Gopal PR | 2004 | J Indian Med Assoc2004，102，2： | 1 |
| 18 | Correlation between structural, magnetic, and dielectric properties of manganese substituted cobalt ferrite显示文摘 | Ramana C V Kolekar Y D Kamala Bharathi K | 2013 | Journal of Applied Physics2013，114，： | 1 |
| 19 | Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options显示文摘 | Srivastava SK Ramana KV Bhatnagar A | | 0，，03： | 1 |
| 20 | Aldose reductase inhibi- tion prevents colon cancer growth by restoring phosphatase and ten- sin homolog through modulation of miR-21 and FOXO3a 显示文摘 | Saxena A Tammali R Ramana KV | 2013 | Antiox- id Redox Signal2013，18，11： | 1 |
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