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| 1 | FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle. | Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes | 2020 | Data Intelligence2020，2，1： | 26 |
| 2 | Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens显示文摘Objective:To evaluate the antibacterial properties ot Allium sativum(garlic) cloves and Zingiber officinale(ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.Methods:The cloves of garlic and rhizomes of ginger were extracted with 95%(v/v) ethanol.The ethanolic extracts were subjected to antibacterial sensitivity test against clinical pathogens.Results:Anti-bacterial potentials of the extracts of two crude garlic cloves and ginger rhizomes were tested against five gram negative and two gram positive multi-drug resistant bacteria isolates.All the bacterial isolates were susceptible to crude extracts of both plants extracts.Except Enterobacter sp.and Klebsiella sp.,all other isolates were susceptible when subjected to ethanolic extracts of garlic and ginger.The highest inhibition zone was observed with garlic(19.4S mm) against Pseudomonas aeruginosa(P.aeruginosa).The minimal inhibitory concentration was as low as 67.00 μg/mL against P.aeruginosa.Conclusions:Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug resistant microbial diseases and further evaluation is necessary. | Ponmurugan Karuppiah Shyamkumar Rajaram | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，8： | 14 |
| 3 | Effective and Efficient Feature Selection for Large-scale Data Using Bayes' Theorem显示文摘This paper proposes one method of feature selection by using Bayes theorem. The purpose of the proposed method is to reduce the computational complexity and increase the classification accuracy of the selected feature subsets. The dependence between two attributes (binary) is determined based on the probabilities of their joint values that contribute to positive and negative classification decisions. If opposing sets of attribute values do not lead to opposing classification decisions (zero probability), then the two attributes are considered independent of each other, otherwise dependent, and one of them can be removed and thus the number of attributes is reduced. The process must be repeated on all combinations of attributes. The paper also evaluates the approach by comparing it with existing feature selection algorithms over 8 datasets from University of California, Irvine (UCI) machine learning databases. The proposed method shows better results in terms of number of selected features, classi?cation accuracy, and running time than most existing algorithms. | Subramanian Appavu Alias Balamurugan Ramasamy Rajaram | 2009 | International Journal of Automation and computing2009，6，1： | 7 |
| 4 | 抗氧化剂和吲哚生物碱在粉红色和白色长春花植株不同部位中的分布(英文)显示文摘目的研究抗氧化剂和吲哚生物碱在2种长春花(粉红色和白色)植株不同部位的分布。方法通过检测无酶活性的抗氧化分子含量和抗氧化酶活性测定抗氧化能力。无酶活性的抗氧化分子包括抗坏血酸、α-生育酚和还原型谷胱甘肽。抗氧化酶包括超氧化物歧化酶、抗坏血酸过氧化物酶、过氧化氢酶、过氧化物酶和多酚氧化酶。所用样品为从田间收集到的植株的根、茎、叶、花和豆荚。结果与其他部位比较,根和茎中抗氧化剂的含量较高,花和豆荚中含量最低。粉红色长春花中抗氧化剂和生物碱含量较高。叶中抗氧化酶的活性较高,但吲哚生物碱的含量在粉红色长春花的根中较高。结论对于抗氧化剂和生物碱含量而言,粉红色长春花更适合培养。 | Cheruth Abdul JALEEL Rajaram PANNEERSELVAM | 2007 | 中国药理学与毒理学杂志2007，21，6： | 5 |
| 5 | A Generic Workflow for the Data FAIRification Process显示文摘The FAIR guiding principles aim to enhance the Findability,Accessibility,Interoperability and Reusability of digital resources such as data,for both humans and machines.The process of making data FAIR(“FAIRification”)can be described in multiple steps.In this paper,we describe a generic step-by-step FAIRification workflow to be performed in a multidisciplinary team guided by FAIR data stewards.The FAIRification workflow should be applicable to any type of data and has been developed and used for“Bring Your Own Data”(BYOD)workshops,as well as for the FAIRification of e.g.,rare diseases resources.The steps are:1)identify the FAIRification objective,2)analyze data,3)analyze metadata,4)define semantic model for data(4a)and metadata(4b),5)make data(5a)and metadata(5b)linkable,6)host FAIR data,and 7)assess FAIR data.For each step we describe how the data are processed,what expertise is required,which procedures and tools can be used,and which FAIR principles they relate to. | Annika Jacobsen Rajaram Kaliyaperumal Luiz Olavo Bonino da Silva Santos Barend Mons Erik Schultes Marco Roos Mark Thompson | 2020 | Data Intelligence2020，2，1： | 5 |
| 6 | Aeromagnetic signatures of Precambrian shield and suture zones of Peninsular India显示文摘In many Precambrian provinces the understanding of the tectonic history is constrained by limited exposure and aeromagnetic data provide information below the surface cover of sediments,water,etc.and help build a tectonic model of the region.The advantage of using the aeromagnetic data is that the data set has uniform coverage and is independent of the accessibility of the region.In the present study,available reconnaissance scale aeromagnetic data over Peninsular India are analyzed to understand the magnetic signatures of the Precambrian shield and suture zones thereby throwing light on the tectonics of the region.Utilizing a combination of differential reduction to pole map,analytic signal,vertical and tilt derivative and upward continuation maps we are able to identify magnetic source distribution,tectonic elements,terrane boundaries,suture zones and metamorphic history of the region.The magnetic sources in the region are mainly related to charnockites,iron ore and alkaline intrusives.Our analysis suggests that the Chitradurga boundary shear and Sileru shear are terrane boundaries while we interpret the signatures of Palghat Cauvery and Achankovil shears to represent suture zones.Processes like metamorphism leave their signatures on the magnetic data:prograde granulites(charnockites)and retrograde eclogites are known to have high susceptibility.We fnd that charnockites intruded by alkali plutons have higher magnetization compared to the retrogressed charnockites.We interpret that the Dharwar craton to the north of isograd representing greenschist to amphibolite facies transition,has been subjected to metamorphism under low geothermal conditions.Some recent studies suggest a plate tectonic model of subductionecollisioneaccretion tectonics around the Palghat Cauvery shear zone(PCSZ).Our analysis is able to identify several west to east trending high amplitude magnetic anomalies with deep sources in the region from Palghat Cauvery shear to Achankovil shear.The magnetic high associated with PCSZ may represent the extruded high pressureeultra high temperature metamorphic belt(granulites at shallow levels and retrogressed eclogites at deeper levels)formed as a result of subduction process.The EW highs within the Madurai block can be related to the metamorphosed clastic sediments,BIF and mafc/ultramafc bodies resulting from the process of accretion. | Mita Rajaram S.P.Anand | 2014 | Geoscience Frontiers2014，5，1： | 3 |
| 7 | Human Blood CXCR5 + CD4 + T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion显示文摘 | Rimpei Morita Nathalie Schmitt Salah-Eddine Bentebibel Rajaram Ranganathan Laure Bourdery Gerard Zurawski Emile Foucat Melissa Dullaers SangKon Oh Natalie Sabzghabaei Elizabeth M. Lavecchio Marilynn Punaro Virginia Pascual Jacques Banchereau Hideki Ueno | 2011 | Immunity2011，，1： | 2 |
| 8 | Design and synthesis of 4-(1-(4-chlorobenzyl)-2,3-dioxoindolin-5-yl)-1 -(4-substituted/unsubstituted benzylidene) semicarbazide:Novel agents with analgesic,anti-inflammatory and ulcerogenic properties显示文摘靛红 semicarbazide 衍生物(7a7j ) 的一个新系列被分光镜的工具和元素的分析综合并且描绘。止痛剂并且反煽动性的屏蔽分别地用尾巴轻打技术和导致 carrageenan 的脚爪浮肿测试被执行。ulcerogenicity 也为所有混合物被决定。一些混合物显示出这项活动的中等改进。在综合衍生物之中,复合 7d 显示出更高的止痛剂, antiinflammatory 并且参考药的三分之一个个溃疡索引。 | Chinnasamy Rajaram Prakash Sundararajan Raja Govindaraj Saravanan | 2012 | Chinese Chemical Letters2012，23，5： | 2 |
| 9 | Synthesis and Characterization of Rare Earth Ion Doped Nano ZnO显示文摘Zinc oxide(ZnO) doped with erbium at different concentrations was synthesized by solid-state reaction method and characterized by X-ray diffraction(XRD), scanning electron microscopic(SEM), UVabsorption spectroscopy, photoluminescence(PL) study and vibrating sample magnetometer. The XRD studies exhibit the presence of wurtzite crystal structure similar to the parent compound ZnO in 1% Er^(3+)doped Zn O,suggesting that doped Er^(3+)ions sit at the regular Zn^(2+)sites. However, same studies spread over the samples with Er^(3+)content>1% reveals the occurrence of secondary phase. SEM images of 1% Er^(3+)doped ZnO show the polycrystalline nature of the synthesized sample. UV-visible absorption spectrum of Er^(3+)doped ZnO nanocrystals shows a strong absorption peak at 388 nm due to ZnO band to band transition. The PL study exhibits emission in the visible region, due to excitonic as well as defect related transitions. The magnetizationfield curve of Er^(3+)doped ZnO nanocrystals showed ferromagnetic property at room-temperature. | Rita John Rajaram Rajakumari | 2012 | Nano-Micro Letters2012，4，2： | 2 |
| 10 | Enzyme immobilization: an overview on techniques and support materials显示文摘 | Datta S Christena L R Rajaram Y R S | 2013 | 3 Biotech2013，3，1： | 1 |
| 11 | High-risk human papillomavirus,tumor suppressor protein p53 and mitomycin-C in invasive squamous cell carcinoma cervix显示文摘 | Gupta G Agarwal S | 2006 | Indian J Cancer2006，43，4： | 1 |
| 12 | Physiological and genetic changes of irrigated wheat in the post-green revolution period and approaches for meeting projected global demand 显示文摘 | REYNOLDS M P RAJARAM S SAYRE K D | 1999 | Crop Sci1999，39，： | 1 |
| 13 | Preliminary study on the antimicrobial activity of Enicostemma littorale using different solvents显示文摘Objective:To study the antimicrobial activity of Enicostemma littorale(E.littorale) using different solvents.Methods:Chloroform,methanol and acetone extracts of different parts of E.littorale(leaf,stem and root) were evaluated for antimicrobial activity using disc diffusion method against some gram-negative species such as Escherichia coli,Klebsiella pnemoniae, Pseudomonas aeruginosa,Salmonella typhi and gram-positive species Staphylococcus aureus, Bacillus cereus,Bacillus subtilis and two fugal species viz.,Aspergillus fumigates and Aspergillus flavus.Results:The chloroform extracts showed the highest antibacterial activity.Among leaf, stem and root extracts,the stem extracts showed maximum antibacterial activity.All of the used extracts had no significant antifungal activity against Aspergillus fumigates and Aspergillus flavus.The chloroform stem extract showed highest activity(about 20 mm inhibition zone) against Bacillus subtilis(at 500 tng/mL) followed by the methanolic stem extract which showed highest activity against the same organism.The lowest antibacterial activity was observed by the acetone leaf extract(about 8 mm inhibition zone) against Escherichia coli.Conclusions:The findings of the study indicate littorale could also be a new source for antibiotics discovery. | Pitchamuthu Abirami Muthiah Gomathinayagam Rajaram Panneerselvam | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，7： | 1 |
| 14 | Template synthesis of highly crystalline and monodisperse iron oxide pigments of nanosize显示文摘 | Sreeram K J Indumathy R Rajaram A | 2006 | Mater Res Bull2006，41，： | 1 |
| 15 | Growth and characterization of elec?trodeposited Cu(ln,Al)Sez thin films显示文摘 | Prasher D Rajaram P | 2011 | Thin Solid Films2011，519，19： | 1 |
| 16 | Survival after cardiopulmonary resuscitation in an urban Indian hospital显示文摘 | Rajaram R Rajagopalan RE Pai M | 1999 | Natl Med J India1999，12，2： | 1 |
| 17 | The benefits of advance booking discount programs : model and analysis 显示文摘 | Tang C S Rajaram K Alptekinoglu A | 2004 | Management Science2004，50，4： | 1 |
| 18 | Optimizing inventory replenishment of retail fashion products 显示文摘 | Fisher M Rajaram K Raman K | 2001 | Manufacturing and Service Operations Management2001，3，3： | 1 |
| 19 | Inheritance of slow rusting resistance in wheat 显示文摘 | Das M K Rajaram S Mundt C C | 1992 | Crop Sci1992，32，： | 1 |
| 20 | The Interference of Polarized Light as an Early Example of Berry's Phase 显示文摘 | RAMASESHAN S RAJARAM NITYANANDA | 1986 | Current Science1986，5524，： | 1 |
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