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| 1 | GLOBAL SUPERCONVERGENCE OF THE MIXED FINITE ELEMENT METHODS FOR 2-D MAXWELL EQUATIONS显示文摘Superconvergence of the mixed finite element methods for 2-d Maxwell equations is studied in this paper. Two order of superconvergent factor can be obtained for the k-th Nedelec elements on the rectangular meshes. | Jia-fuLin QunLin | 2003 | Journal of Computational Mathematics2003，21，5： | 7 |
| 2 | Investigation on the Interactions between Pirarubiein and Phospholipids显示文摘 | Cong Wenjuan Liu Qingfei Liang Qunlin | 2009 | Biophys ehem2009，143，3： | 1 |
| 3 | Accuracy Analysis of the Adini Element for Biharmonic Equation显示文摘In this paper,we consider the solution of the biharmonic equation using Adini nonconforming finite element,and report new results of the asympiotic error expansions of the interpolation error functionals and nonconforming remainder.These expansions are used to develop two extrapolation formulas and a series of sharp error estimates.Finally,the numerical results have verified the extrapolation theory. | PingLUO QunLIN | 2004 | Acta Mathematica Sinica,English Series2004，20，1： | 1 |
| 4 | A gradient HPLC method for the quality control of chlorogenic acid,linarin and luteolin in Flos Chrysanthemi Indici suppository显示文摘 | Qunlin Zhang Jun Li Chao Wang | 2007 | J Pharm and Biom Anal2007，43，： | 1 |
| 5 | Recent Progress in Computerization of TCM显示文摘 | Zhi Liu Jingqi Yan Qunlin Tang Qingli Li | 2006 | 通讯和计算机(中英文版)2006，3，7： | 1 |
| 6 | Phosphorylated VEGFR2 and hypertension: potential biomarkers to indicate VEGF-dependency of advanced breast cancer in anti-angiogenic therapy显示文摘 | Minhao Fan Jian Zhang Zhonghua Wang Biyun Wang Qunlin Zhang Chunlei Zheng Ting Li Chen Ni Zhenhua Wu Zhimin Shao Xichun Hu | 2014 | Breast Cancer Research and Treatment2014，，1： | 1 |
| 7 | A gradient HPLC method for the quality control of chlorogenic acid, hnarin and luteolin in Flos Chrysanthemi Indicisuppository 显示文摘 | Qunlin Zhang Jun Lia Chao Wanga | 2007 | Journal of Pharmaceutical and Biomedical Analysis2007，2，43： | 1 |
| 8 | Computed tomographic-guided iodine-125 interstitial implants for malignant thoracic tumors显示文摘 | Qiming Huang Jin Chen Qunlin Chen Qingquan Lai Siqing Cai Kaidong Luo Zhengyu Lin | 2013 | European Journal of Radiology2013，，11： | 1 |
| 9 | Sensitive determination of phenolic compounds using high-performance liquid chromatography with cerium(Ⅳ)-rhodamine 6G-phenolic compound chemiluminescence detection 显示文摘 | Zhang Qunlin Cui Hua Aung M | 2005 | J Chromatogr A2005，1095，： | 1 |
| 10 | Study of Aldo-keto Reductase 1C3 Inhibitor with Novel Framework for Treating Leukaemia Based on Virtual Screening and In vitro Biological Activity Testing显示文摘Aldo-keto reductase 1C3(AKR1C3)is a potential target for the treatment of acute myeloid leukaemia and T-cell acute lymphoblastic leukaemia.In this study,pharmacophore models,molecular docking and virtual screening of target prediction were used to find a potential AKR1C3 inhibitor.Firstly,eight bacteriocin derivatives(Z1-Z8)were selected as training sets to construct 20 pharmacophore models.The best pharmacophore model MODEL_016 was obtained by Decoy test(the enrichment degree was 21.5117,and the fitting optimisation degree was 0.9668).Secondly,MODEL_016 was used for the virtual screening of ZINC database.Thirdly,the hit 83256 molecules were docked into the AKR1C3 protein.Compared to the total scores and interactions between compounds and protein,16532 candidate compounds with higher docking scores and interactions with important residues PHE306 and TRP227 were screened.Lastly,eight compounds(A1-A8)that had good absorption,distribution,metabolism,excretion and toxicity(ADMET)properties were obtained by target prediction.Compounds A3 and A7 with high total score and good target prediction results were selected for in vitro biological activity test,whose IC_(50) values were 268.3 and 88.94µmol/L,respectively.The results provide an important foundation for the discovery of novel AKR1C3 inhibitors.The research methods used in this study can also provide important references for the research and development of new drugs. | LIU Fei LI Ren YE Jing REN Yujie TANG Zhipeng LI Rongchen ZHANG Cuihua LI Qunlin | 2021 | Chemical Research in Chinese Universities2021，37，3： | 0 |
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