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| 1 | A comparison of the energy consumption and carbon emissions for different modes of transportation in open-cut coal mines显示文摘Transportation accounts for 80% of open-cut coal mine carbon emissions.With regard to the energy consumption and carbon emissions of transportation within an open-cut mine,this paper systematically compared the work and energy consumption of a truck and belt conveyor on a theoretical basis,and constructed a model to calculate the energy consumption of open-cut mine transportation.Life cycle carbon emission factors and power consumption calculation model were established through a Process Analysis–Life Cycle Analysis(PA–LCA).The following results were obtained:(1) the energy consumption of truck transportation was four to twelve times higher than that of the belt conveyor;(2) the CO2 emissions from truck transportation were three to ten times higher than those of the belt conveyor;(3) with the increase in the slope angle for transportation,the ratio of truck to belt conveyor for both energy consumption and carbon emissions gradually decreased;(4) based on 2013 prices in China,the energy cost of transportation using a belt conveyor in open-cut coal mines could save 0.6–2.4 Yuan/(t km) compared to truck transportation. | Liu Fuming Cai Qingxiang Chen Shuzhao Zhou Wei | 2015 | International Journal of Mining Science and Technology2015，25，2： | 12 |
| 2 | Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer显示文摘To flourish,cancers greatly depend on their surrounding tumor microenvironment(TME),and cancer-associated fibroblasts(CAFs)in TME are critical for cancer occurrence and progression because of their versatile roles in extracellular matrix remodeling,maintenance of sternness,blood vessel formation,modulation of tumor metabolism,immune response,and promotion of cancer cell proliferation,migration,invasion,and therapeutic resistance.CAFs are highly heterogeneous stromal cells and their crosstalk with cancer cells is mediated by a complex and intricate signaling network consisting of transforming growth factor-beta,phosphoinositide 3-kinase/AKT/mammalian target of rapamycin,mitogen-activated protein kinase,Wnt,Janus kinase/signal transducers and activators of transcription,epidermal growth factor receptor,Hippo,and nuclear factor kappa-light-chain-enhancer of activated B cells,etc.,signaling pathways.These signals in CAFs exhibit their own special characteristics during the cancer progression and have the potential to be targeted for anticancer therapy.Therefore,a comprehensive understanding of these signaling cascades in interactions between cancer cells and CAFs is necessary to fully realize the pivotal roles of CAFs in cancers.Herein,in this review,we will summarize the enormous amounts of findings on the signals mediating crosstalk of CAFs with cancer cells and its related targets or trials.Further,we hypothesize three potential targeting strategies,including,namely,epithelial-mesenchymal common targets,sequential target perturbation,and crosstalk-directed signaling targets,paving the way for CAF-directed or host cell-directed antitumor therapy. | Fanglong Wu Jin Yang Junjiang Liu Ye Wang Jingtian Mu Qingxiang Zeng Shuzhi Deng Hongmei Zhou | 2021 | Signal Transduction and Targeted Therapy2021，6，7： | 9 |
| 3 | 3D stability analysis method of concave slope based on the Bishop method显示文摘In order to study the stability control mechanism of a concave slope with circular landslide, and remove the influence of differences in shape on slope stability, the limit analysis method of a simplified Bishop method was employed. The sliding body was divided into strips in a three-dimensional model, and the lateral earth pressure was put into mechanical analysis and the three-dimensional stability analysis methods applicable for circular sliding in concave slope were deduced. Based on geometric structure and the geological parameters of a concave slope, the influence rule of curvature radius and the top and bottom arch height on the concave slope stability were analyzed. The results show that the stability coefficient decreases after growth, first in the transition stage of slope shape from flat to concave, and it has been confirmed that there is a best size to make the slope stability factor reach a maximum. By contrast with average slope, the stability of a concave slope features a smaller range of ascension with slope height increase, which indicates that the enhancing effect of a concave slope is apparent only with lower slope heights. | Zhang Tianwen Cai Qingxiang Han Liu Shu Jisen Zhou Wei | 2017 | International Journal of Mining Science and Technology2017，27，2： | 6 |
| 4 | Synthesis of a reduction-sensitive Bletilla striata polysaccharide amphiphilic copolymer显示文摘Recently, much special attention has been focused on the development of amphiphilic copolymers.Herein, a reduction-sensitive stearic acid grafted-Bletilla striata polysaccharide copolymer(BSP-ss-SA)was synthesized and characterized. BSP-ss-SA copolymer could spontaneously form micelles with an average particle size of(106 ? 4.36) nm. Particle sizes were dramatically larger under 10 mmol/L dithiothreitol(DTT) than that in absence of 10 mmol/L DTT. Docetaxel loading content and encapsulation efficiency of micelles were 5.94 wt% and 72.75 wt%, respectively. The docetaxel release rate in vitro in micelles could be remarkably accelerated in pH 7.4 phosphate buffer solution(PBS) containing 10 mmol/L DTT compared with that of micelles(0 mmol/L DTT). Furthermore, MTT results demonstrated the anticancer activities in vitro of docetaxel-loaded BSP-ss-SA micelles on HepG2 were superior to that of docetaxel injection. BSP-ss-SA copolymer might be a promising nanocarrier for cancer chemotherapy drugs. | Dandan Sun Miao Wang Danyang Ji Jin Qiao Tong He Xin Liu Qingxiang Guan | 2018 | Chinese Chemical Letters2018，29，6： | 5 |
| 5 | TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3β to TBK1显示文摘 | Yunfei Qin Qingxiang Liu Shuo Tian Weihong Xie Jun Cui Rong-Fu Wang | 2016 | Cell Research2016，26，5： | 3 |
| 6 | Promoting effect of polyoxyethylene octylphenol ether on Cu/ZnO catalysts for low-temperature methanol synthesis显示文摘Cu/ZnO catalysts were prepared by the co-precipitation method with the addition of OP-10(polyoxyethylene octylphenol ether) and were chemically and structurally characterized by means of XRD,BET,H2-TPR,CO-TPD and N2O-titration.The effect of OP-10 addition on the activity of Cu/ZnO for the slurry phase methanol synthesis at 150 ℃ was evaluated.The results showed that Cu/ZnO prepared with addition of 8% OP-10(denoted as C8) exhibited the promoted activity for the methanol synthesis.The conversion of CO and the STY(space time yield) of methanol were 42.5% and 74.6% higher than those of Cu/ZnO prepared without addition of OP-10(denoted as C0),respectively.The precursor of C8 contained more aurichalcite and rosasite,and the concerted effect of Cu-Zn in C8 was found to be stronger than that in C0.Compared with C0,C8 showed smaller particle size,lower reduction temperature and larger BET and Cu surface areas. | Ling Liu Tiansheng Zhao Qingxiang Ma Yufang Shen | 2009 | Journal of Natural Gas Chemistry2009，18，3： | 3 |
| 7 | ISAR cross-range scaling based on the MUSIC technique显示文摘Cross-range scaling plays an important role in the inverse synthetic aperture radar(ISAR) imaging. Many of the published cross-range scaling algorithms are based on the fast Fourier transformation(FFT). However, the FFT technique is resolution limited, so that the FFT-based algorithms will fail in the rotation velocity(RV) estimation of the slow rotation target. In this paper,we propose an accurate cross-range scaling algorithm based on the multiple signal classification(MUSIC) method. We first select some range bins with the mono-component linear frequency modulated(LFM) signal model. Then, we dechirp the signal of each selected range bin into the form of sinusoidal signal, and utilize the super-resolution MUSIC technique to accurately estimate the frequency. After processing all the range bins, a linear relationship related to the RV can be obtained. Eventually, the ISAR image can be scaled. The proposal can precisely estimate the small RV of the slow rotation target with low computational complexity. Furthermore, the proposal can also be used in the case of cross-range scaling for the sparse aperture data. Experimental results with the simulated and raw data validate the superiority of the novel method. | LIU Qiuchen WANG Yong ZHANG Qingxiang | 2020 | Journal of Systems Engineering and Electronics2020，31，5： | 2 |
| 8 | Detecting and adjusting temporal inhomogeneity in Chinese mean surface air temperature data显示文摘 | Qingxiang Li Xiaoning Liu Hongzheng Zhang Peterson Thomas C. Easterling David R | | Advances in Atmospheric Sciences0，，： | 2 |
| 9 | Monodisperse amino-modified nanosized zero-valent iron for selective and recyclable removal of TNT: Synthesis, characterization, and removal mechanism显示文摘Nitroaromatic explosives are major pollutants produced during wars that cause serious environmental and health problems. The removal of a typical nitroaromatic explosive, 2,4,6-trinitrotoluene(TNT), from aqueous solution, was conducted using a new recyclable magnetic nano-adsorbent(Fe@SiO_(2) –NH_(2)). This adsorbent was prepared by grafting amino groups onto Fe@SiO_(2) particles with a well-defined core-shell structure and demonstrated monodispersity in solution. The removal performance of the nano-adsorbent towards TNT was found to be 2.57 and 4.92 times higher than that towards two analogous explosives, 2,4-dinitrotoluene(2,4-DNT) and 2-nitrotoluene(2-NT), respectively, under neutral conditions. The difference in the removal performance among the three compounds was further compared in terms of the effects of different conditions(pH value, ionic strength, humic acid concentration, adsorbent modification degree and dosage, etc.) and the electrostatic potential distributions of the three compounds. The most significant elevation is owing to modification of amino on Fe@SiO_(2) which made a 20.7% increase in adsorption efficiency of TNT. The experimental data were well fit by the pseudo-second-order kinetic model and the Freundlich adsorption isotherm model, indicating multilayer adsorption on a heterogeneous surface. The experimental results and theoretical considerations show that the interactions between Fe@SiO_(2) –NH_(2) NPs and TNT correspond to dipole-dipole and hydrophobic interactions. These interactions should be considered in the design of an adsorbent. Furthermore, the adaptability to aqueous environment and excellent regeneration capacity of Fe@SiO_(2) –NH_(2) NPs makes these remediation materials promising for applications. | Jing Li Qingxiang Zhou Miao Li Yongli Liu Qinan Song | 2021 | Journal of Environmental Sciences2021，33，5： | 2 |
| 10 | σ-LET curve obtained with heavy ions accelerated by HIRFL显示文摘σ-LET curve is one of the important factors for orbital SEU rate prediction. SEU cross sections of static random access memory (SRAM) IDT71256 were obtained with 35 MeV/u 36Ar ions and 15.14 MeV/u 136Xe ions, accelerated by Heavy Ion Research Facility in Lanzhou (HIRFL), fitted with Weibull and Lognormal function to obtain the whole σ-LET curve. The SEU rates of IDT71256 in geosynchronous and two sunsynchronous orbits were predicted with fitting parameters. | Qingxiang Zhang Mingdong Hou Jie Liu Honglou Zhen | 2002 | Chinese Science Bulletin2002，47，17： | 2 |
| 11 | Modulating the thermal conductivity of silicon nanowires via surface amorphization显示文摘We perform non-equilibrium molecular dynamics calculations to study the heat transport in crystalline-core amorphous-shell silicon nanowires(SiNWs).It is found that the thermal conductivity of the core-shell SiNWs is closely related to the cross-sectional area ratio of amorphous shell.Through shell amorphization,an 80%reduction in thermal conductivity compared to crystalline SiNWs with the same size can be achieved,due to the non-propagating heat diffusion in the amorphous region.In contrast to the strong temperature-dependent thermal conductivity of crystalline SiNWs,the core-shell SiNWs only show weak temperature dependence.In addition,an empirical relation is proposed to accurately predict the thermal conductivity of the core-shell SiNWs based on the rule of mixture.The present work demonstrates that SiNWs with an amorphized shell are promising candidates for thermoelectric applications. | LIU XiangJun ZHANG Gang PEI QingXiang ZHANG YongWei | 2014 | Science China(Technological Sciences)2014，57，4： | 2 |
| 12 | Calculation of slope-cover height under price fluctuation in open-pit mines显示文摘Leaving ditches between adjacent mining areas can effectively reduce re-stripping in the latter mining area and simultaneously lead to an increment in internal dumping costs in the former mining area. This paper establishes calculation models for these two marginal costs. The optimizing model for slope cover height can be determined by including marginal cost models in the objective function. The paper has two main contributions:(a) it fully considers redistribution of dumping space in the model;(b) it introduces price fluctuations and cash discounts in the model. We use the typical open-pit mine as an example to test and prove the model. We conclude that a completely covered slope is reasonable in Haerwusu open pit mine; in addition to an increasing price index, the slope cover height can be reduced; and that price changes are one of the most important influencing factors of slope cover height optimization in an open-pit mine. | Ma Jinyan Cai Qingxiang Liu Fuming Chen Shuzhao | 2014 | International Journal of Mining Science and Technology2014，24，3： | 1 |
| 13 | Stress - Strain Behaviors Simulation of High Chromium Steel at Elevated Temperatures显示文摘 | Ligang Liu Qiang Li Bo Liao Yukui Gao Yuhui Wang Xuejun Ren and Qingxiang Yang | 2010 | Journal of Ma- terials Engineering and Performance2010，，19： | 1 |
| 14 | The driving forces in the Inclusion complexation of cyclodextrins 显示文摘 | Lei Liu Guo QingXiang | 2002 | Journal of Inclusion Phenomena and Macrocyclic Chemistry2002，42，： | 1 |
| 15 | Enumeration and molecular characterization of circulating tumor cell using an in vivo capture system in squamous cell carcinoma of head and neck显示文摘Objective: Detection rate and isolation yield of circulating tumor cell(CTC) are low in squamous cell carcinoma of head and neck(SCCHN) with in vitro approaches due to limited sample volumes. In this study, we applied the Cell Collector to capture CTC in vivo from peripheral blood.Methods: In total, the study included 22 cases with 37 times of detection. All of the patients were newly diagnosed with locally advanced or metastatic SCCHN, including laryngocarcinoma(40.9%, 9/22) and hypopharyngeal carcinoma(59.1%, 13/22). All patients received CTC analysis before treatment. Three patients received induction chemotherapy. Sixteen patients received surgical therapy, of which 13 patients received postoperative detection. Two patients received both induction chemotherapy and surgery treatment. Patients underwent two successive Cell Collector applications 24 h before and 7 d after surgical therapy. Nine healthy volunteers were enrolled as the control group. Epidermal growth factor receptor variant type Ⅲ(EGFRⅧ)expression was analyzed with fluorescent dye labeled antibody.Results: With Cell Collector isolation, 72.7%(16/22) of the patients were positive for ≥1 CTC(CTC; range,1–17 cells) before treatments and 46.7%(7/15) of patients were CTC positive for ≥1 CTC(CTC; range, 1–29 cells) after surgical therapy. Moreover, the detection rate of Cell Collector(82.4%, 14/17; CTC count range, 0–17)in advanced SCCHN(stage Ⅲ–Ⅳ) was much higher than that in early stages(stage Ⅰ–Ⅱ, 40.0%, 2/5; CTC count range, 0–2)(P<0.05). EGFRⅧ expression of CTC was also analyzed with fluorescence staining. One CTCEGFRⅧ-positive patient was detected from six CTC-positive patients, and the positive expression of EGFRⅧ was also found in the tumor tissue of this patient.Conclusions: In vivo detection of CTCs had high sensitivity in SCCHN, which might improve CTC application in clinic. | Haidong Zhang Shanchun Gong Yaqun Liu Longjun Liang Shuangba He Qingxiang Zhang Mingyuan Si Zhenkun Yu | 2017 | Chinese Journal of Cancer Research2017，29，3： | 1 |
| 16 | F3 peptide-functionalized PEG-PLA nanoparticles co-administrated with tLyp-1 peptide for anti-glioma drug delivery显示文摘 | Quanyin Hu Guangzhi Gu Zhongyang Liu Mengyin Jiang Ting Kang Deyu Miao Yifan Tu Zhiqing Pang Qingxiang Song Lei Yao Huimin Xia Hongzhan Chen Xinguo Jiang Xiaoling Gao Jun Chen | 2013 | Biomaterials2013，，4： | 1 |
| 17 | Phase diagram calculation of high chromium cast irons and influence of its chemical composition显示文摘 | Da Li Ligang Liu Yunkun Zhang Chunlei Ye Xuejun Ren Yulin Yang Qingxiang Yang | 2008 | Materials and Design2008，，2： | 1 |
| 18 | Nylon-6 film grafted with acrylic acid for dissepiment in alkaline storage batteries显示文摘 | Liu Minying Zhao Qingxiang | 2004 | Polymers for advanced technologies2004，15，12： | 1 |
| 19 | Detecting and Adjusting on Temporal Inhomogeneity in Chinese Mean Surface Air Temperature Dataset显示文摘 | Liu Xiaoning Zhang Hongzheng | 2004 | Adv Atmos Sci2004，21，2： | 1 |
| 20 | Coaxial foilless diode显示文摘 | Kong Long Liu Qingxiang Li Xiangqiang | 2014 | AIP Advances2014，4，05： | 1 |
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