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    题名 作者 年代 出处 被引量
1Xueshuantong improves cerebral blood perfusion in elderly patients with lacunar infarction显示文摘A total of 64 patients with acute lacunar infarction were enrolled within 24 hours of onset. The patients received conventional therapy (antiplatelet drugs and hypolipidemic drugs) alone or conventional therapy plus 450 mg Xueshuantong once a day. The main ingredient of the Xueshuantong lyophilized powder used for injection was Panax notoginseng saponins. Assessments were made at admission and at discharge using the National Institutes of Health Stroke Scale, the Activity of Daily Living and the Mini-Mental State Examination. Additionally, the relative cerebral blood flow, relative cerebral blood volume and relative mean transit time in the region of interest were calculated within 24 hours after the onset of lacunar infarction, using dynamic susceptibility contrast magnetic resonance perfusion imaging technology. Patients underwent a follow-up MRI scan after 4 weeks of treatment. There was an improvement in the Activity of Daily Living scores and a greater reduction in the scores on the National Institutes of Health Stroke Scale in the treatment group than in the control group. However, the Mini-Mental State Examination scores showed no significant differences after 4 weeks of treatment. Compared with the control group, the relative cerebral blood flow at discharge had increased and showed a greater improvement in the treatment group. Furthermore, there was a reduction in the relative mean transit time at discharge and the value was lower in the treatment group than in the control group. The experimental findings indicate that Xueshuantong treatment improves neurological deficits in elderly patients with lacunar infarction, and the mechanism may be related to increased cerebral perfusion.Qifeng Gui Yunmei Yang Shihong Ying Minming Zhang 2013Neural Regeneration Research2013,8,9:27
2Latest Progress of the Chinese Meteorological Satellite Program and Core Data Processing Technologies显示文摘In this paper,the latest progress,major achievements and future plans of Chinese meteorological satellites and the core data processing techniques are discussed.First,the latest three FengYun(FY)meteorological satellites(FY-2H,FY-3D,and FY-4A)and their primary objectives are introduced Second,the core image navigation techniques and accuracies of the FY meteorological satellites are elaborated,including the latest geostationary(FY-2/4)and polar-orbit(FY-3)satellites.Third,the radiometric calibration techniques and accuracies of reflective solar bands,thermal infrared bands,and passive microwave bands for FY meteorological satellites are discussed.It also illustrates the latest progress of real-time calibration with the onboard calibration system and validation with different methods,including the vicarious China radiance calibration site calibration,pseudo invariant calibration site calibration,deep convective clouds calibration,and lunar calibration.Fourth,recent progress of meteorological satellite data assimilation applications and quantitative science produce are summarized at length.The main progress is in meteorological satellite data assimilation by using microwave and hyper-spectral infrared sensors in global and regional numerical weather prediction models.Lastly,the latest progress in radiative transfer,absorption and scattering calculations for satellite remote sensing is summarized,and some important research using a new radiative transfer model are illustrated.Peng ZHANG Qifeng LU Xiuqing HU Songyan GU Lei YANG Min MIN Lin CHEN Na XU Ling Sun Wenguang BAI Gang MA Di XIAN 2019Advances in Atmospheric Sciences2019,36,9:26
3Time-frequency response spectrum of rotational ground motion and its application显示文摘The rotational seismic motions are estimated from one station records of the 1999 Jiji (Chi-Chi), Taiwan, earthquake based on the theory of elastic plane wave propagation. The time-frequency response spectrum (TFRS) of the rota-tional motions is calculated and its characteristics are analyzed, then the TFRS is applied to analyze the damage mechanism of one twelve-storey frame concrete structure. The results show that one of the ground motion components can not reflect the characteristics of the seismic motions completely; the characteristics of each component, especially rotational motions, need to be studied. The damage line of the structure and TFRS of ground motion are important for seismic design, only the TFRS of input seismic wave is suitable, the structure design is reliable.Wei Che Qifeng Luo 2010Earthquake Science2010,23,1:15
4MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang 2014Protein & Cell2014,5,11:14
5FY-3E:The First Operational Meteorological Satellite Mission in an Early Morning Orbit显示文摘Fengyun-3 E(FY-3E),the world’s first early-morning-orbit meteorological satellite for civil use,was launched successfully at the Jiuquan Satellite Launch Center on 5 July 2021.The FY-3E satellite will fill the vacancy of the global early-morning-orbit satellite observation,working together with the FY-3C and FY-3D satellites to achieve the data coverage of early morning,morning,and afternoon orbits.The combination of these three satellites will provide global data coverage for numerical weather prediction(NWP)at 6-hour intervals,effectively improving the accuracy and time efficiency of global NWP,which is of great significance to perfect the global earth observing system.In this article,the background and meteorological requirements for the early-morning-orbit satellite are reviewed,and the specifications of the FY-3E satellite,as well as the characteristics of the onboard instrumentation for earth observations,are also introduced.In addition,the ground segment and the retrieved geophysical products are also presented.It is believed that the NWP communities will significantly benefit from an optimal temporal distribution of observations provided by the early morning,mid-morning,and afternoon satellite missions.Further benefits are expected in numerous applications such as the monitoring of severe weather/climate events,the development of improved sampling designs of the diurnal cycle for accurate climate data records,more efficient monitoring of air quality by thermal infrared remote sensing,and the quasicontinuous monitoring of the sun for space weather and climate.Peng ZHANG Xiuqing HU Qifeng LU Aijun ZHU Manyun LIN Ling SUN Lin CHEN Na XU 2022Advances in Atmospheric Sciences2022,39,1:13
6Adaptive optimization methodology based on Kriging modeling and a trust region method显示文摘Surrogate-Based Optimization(SBO) is becoming increasingly popular since it can remarkably reduce the computational cost for design optimizations based on high-fidelity and expensive numerical analyses. However, for complicated optimization problems with a large design space, many design variables, and strong nonlinearity, SBO converges slowly and shows imperfection in local exploitation. This paper proposes a trust region method within the framework of an SBO process based on the Kriging model. In each refinement cycle, new samples are selected by a certain design of experiment method within a variable design space, which is sequentially updated by the trust region method. A multi-dimensional trust-region radius is proposed to improve the adaptability of the developed methodology. Further, the scale factor and the limit factor of the trust region are studied to evaluate their effects on the optimization process. Thereafter, different SBO methods using error-based exploration, prediction-based exploitation, refinement based on the expected improvement function, a hybrid refinement strategy, and the developed trust-regionbased refinement are utilized in four analytical tests. Further, the developed optimization methodology is employed in the drag minimization of an RAE2822 airfoil. Results indicate that it has better robustness and local exploitation capability in comparison with those of other SBOChunna LI Qifeng PAN 2019Chinese Journal of Aeronautics2019,32,2:13
7Hes1 Knockdown Exacerbates Ischemic Stroke Following tMCAO by Increasing ER Stress-Dependent Apoptosis via the PERK/ eIF2a/ATF4/CHOP Signaling Pathway显示文摘Apoptosis induced by endoplasmic reticulum(ER)stress plays a crucial role in mediating brain damage after ischemic stroke.Recently,Hes1(hairy and enhancer of split 1)has been implicated in the regulation of ER stress,but whether it plays a functional role after ischemic stroke and the underlying mechanism remain unclear.In this study,using a mouse model of ischemic stroke via transient middle cerebral artery occlusion(tMCAO),we found that Hes1 was induced following brain injury,and that siRNA-mediated knockdown of Hes1 increased the cerebral infarction and worsened the neurological outcome,suggesting that Hes1 knockdown exacerbates ischemic stroke.In addition,mechanistically,Hes1 knockdown promoted apoptosis and activated the PERK/eIF2a/ATF4/CHOP signaling pathway after tMCAO.These results suggest that Hes1 knockdown promotes ER stress-induced apoptosis.Furthermore,inhibition of PERK with the specific inhibitor GSK2606414 markedly attenuated the Hes1 knockdown-induced apoptosis and the increased cerebral infarction as well as the worsened neurological outcome following tMCAO,implying that the protection of Hes1 against ischemic stroke is associated with the amelioration of ER stress via modulating the PERK/eIF2a/ATF4/CHOP signaling pathway.Taken together,these results unveil the detrimental role of Hes1 knockdown after ischemic stroke and further relate it to the regulation of ER stress-induced apoptosis,thus highlighting the importance of targeting ER stress in the treatment of ischemic stroke.Yueyong Li Yingjun Zhang Huangde Fu Huadong Huang Qifeng Lu Houji Qin Yingning Wu Huatuo Huang Guizhen Mao Zhongheng Wei Pinhu Liao 2020Neuroscience Bulletin2020,36,2:12
8Mild hypothermia combined with neural stem cell transplantation for hypoxic-ischemic encephalopathy: neuroprotective effects of combined therapy显示文摘Neural stem cell transplantation is a useful treatment for ischemic stroke, but apoptosis often occurs in the hypoxic-ischemic environment of the brain after cell transplantation. In this study, we determined if mild hypothermia(27–28°C) can increase the survival rate of neural stem cells(1.0 × 105 /μL) transplanted into neonatal mice with hypoxic-ischemic encephalopathy. Long-term effects on neurological functioning of the mice were also examined. After mild hypothermia combined with neural stem cell transplantation, we observed decreased expression levels of inflammatory factor nuclear factor-kappa B and apoptotic factor caspase-3, reduced cerebral infarct volumes, increased survival rate of transplanted cells, and marked improvements in neurological function. Thus, the neuroprotective effects of mild hypothermia combined with neural stem cell transplantation are superior to those of monotherapy. Moreover, our findings suggest that the neuroprotective effects of mild hypothermia combined with neural stem cell transplantation on hypoxic-ischemic encephalopathy are achieved by anti-inflammatory and anti-apoptotic mechanisms.Lin Wang Feng Jiang Qifeng Li Xiaoguang He Jie Ma 2014Neural Regeneration Research2014,9,19:12
9New method for camera pose estimation based on line correspondence显示文摘The key technology of the measuring method of pose shaking of unstable platform based on CCD lies in the camera pose estimation.A new method for camera pose estimation based on line correspondence is put forward in this paper.First,two appropriate lines are selected in the space to establish a local coordinate system,the remaining lines form three-line sets with these two lines respectively and then the angle depth of the lines of the local coordinate system can be obtained by using the linearity of interpretation plane;then the invariance of included angle between spatial coordinate system and camera coordinate system during rigid transformation is used to establish a constraint equation set of angle depth of three lines similar to traditional P3P,and the corresponding angle depth of the third line in the set can be obtained linearly by variable substitution;finally,the rotation matrix can be expressed with quaternion and the pose parameters of camera in the space can be calculated by singular value decomposition(SVD).The static experiment and dynamic experiment verify the accuracy and stability of the algorithm and that the camera pose shocking is within 1°and the 3σ error is superior to 0.3′.The method in this paper can be directly used in the micro-vibration measurement of experimental platform and robot navigation and other fields and is of important theoretical significance and engineering application prospect.LIU JinBo ZHANG XiaoHu LIU HaiBo YUAN Yun ZHU ZhaoKun YU QiFeng 2013Science China(Technological Sciences)2013,56,11:11
10Monocular trajectory intersection method for 3D motion measurement of a point target显示文摘This article proposes a monocular trajectory intersection method,a videometrics measurement with a mature theoretical system to solve the 3D motion parameters of a point target.It determines the target’s motion parameters including its 3D trajectory and velocity by intersecting the parametric trajectory of a motion target and series of sight-rays by which a motion camera observes the target,in contrast with the regular intersection method for 3D measurement by which the sight-rays intersect at one point.The method offers an approach to overcome the technical failure of traditional monocular measurements for the 3D motion of a point target and thus extends the application fields of photogrammetry and computer vision.Wide application is expected in passive observations of motion targets on various mobile beds.YU QiFeng SHANG Yang ZHOU Jian ZHANG XiaoHu LI LiChun 2009Science China(Technological Sciences)2009,52,12:10
11Identifying Influencing Factors for Data Transactions:A Case Study from Shanghai Data Exchange显示文摘In the age of artificial intelligence,firms'internal data are increasingly valuable when merged with each other for inter-firm analysis and predictions.However,the inter-firm data transactions represent a novel challenge on pricing due to the complex nature of data,such as quality information asymmetry,lack of pricing standards,and the negligible marginal cost.This paper conducts a case study at Shanghai Data Exchange to explore the factors that can facilitate the data transactions between buyers and providers.We use interview transcripts from 18 participating firms to construct our three theoretical dimensions:increasing the perceived value,mitigating the cost,and improving the market design.We then browse through 18 factors to assess their value for further improvements.The managerial implications are also discussed.Qifeng Tang Zhiqing Shao Lihua Huang Wenyi Yin Yifan Dou 2020Journal of Systems Science and Systems Engineering2020,29,6:9
12Initial evaluation and assimilation of FY-3A atmospheric sounding data in the ECMWF System显示文摘Fengyuan 3A (FY-3A) was the first Chinese second-generation meteorological satellite. Most of the onboard sensors were used for the first time. Four of the eleven sensors [1] accumulated data for numerical weather forecasting: theLU QiFeng 2011Science China Earth Sciences2011,54,10:8
13Stepwise-Nanocavity-Assisted Transmissive Color Filter Array Microprints显示文摘Visible-light color flters using patterned nanostructures have attracted much interest due to their various advantages such as compactness,enhanced stability,and environmental friendliness compared with traditional pigment or dye-based optical flters.While most existing studies are based on planar nanostructures with lateral variation in size,shape,and arrangement,the vertical dimension of structures is a long-ignored degree of freedom for the structural colors.Herein,we demonstrate a synthetic platform for transmissive color flter array by coordinated manipulations between height-varying nanocavities and their lateral flling fractions.Te thickness variation of those nanocavities has been fully deployed as an alternative degree of freedom,yielding vivid colors with wide gamut and excellent saturation.Experimental results show that the color-rendering capability of the pixelated nanocavities can be still retained as pixels are miniaturized to 500 nm.Crosstalk between closely spaced pixels of a Bayer color flter arrangement was calculated,showing minimal crosstalk for 1μm2 square subpixels.Our work provides an approach to designing and fabricating ultracompact color flter arrays for various potential applications including stained-glass microprints,microspectrometers,and high-resolution image sensing systems.Yasi Wang Mengjie Zheng Qifeng Ruan Yanming Zhou Yiqin Chen Peng Dai Zhengmei Yang Zihao Lin Yuxiang Long Ying Li Na Liu Cheng-Wei Qiu Joel K.W.Yang Huigao Duan 2018Research2018,,1:8
14Vision navigation for aircrafts based on 3D reconstruction from real-time image sequences显示文摘In this paper,we propose a novel vision navigation method based on three-dimensional(3D)reconstruction from real-time image sequences.It adapts 3D reconstruction and terrain matching to establish the correspondence between image points and3D space points and the terrain reference(by using a digital elevation map(DEM)).An adaptive weighted orthogonal iterative pose estimation method is employed to calculate the position and attitude angle of the aircraft.Synthesized and real experiments show that the proposed method is capable of providing accurate navigation parameters for a long-endurance flight without using a global positioning system or an inertial navigation system(INS).Moreover,it can be combined with an INS to achieve an improved navigation result.ZHU ZunShang SU Ang LIU HaiBo SHANG Yang YU QiFeng 2015Science China(Technological Sciences)2015,58,7:8
15Research on 3D Target Pose Tracking and Modeling显示文摘This paper tackles pose tracking and model refinement, one of the fundamental work for 3D photogrammetry. The researches belong to the videometrics, an interdisciplinewhich combines computer vision, digital image processing, photogrammetry and optical measurement. Related works are summarized briefly in this paper. This paper studies the problem of pose tracking for target with 3D model. For the target with accurate 3D model, line model based pose tracking methods are proposed for target which is rich in line features. Experimental results indicate that the proposed methods track the target pose accurately. Normal distance iterative reweighted least squares and distance image iterative least squares methods are proposed to process more general targets. This paper adopts bundle adjustment to tackle pose tracking in image sequence for target with inaccurate 3D line model. The proposed method optimizes the model line parameters and the pose parameters simultaneously. The model line orientation, position and mean angle error, mean position error of the pose are 0.3°,3.5 mm and 0.12°,20.1 mm in simulation experiments of satellite pose tracking. Line features are used to track target pose with unknown 3D model through image sequence. The model line parameters and pose parameters are optimized under the framework of SFM. In simulation experiments, the reconstructed line orientation, position error and mean angle error, mean position error of pose are 0.4°,7.5 mm and 0.16°,23.5 mm.Yang SHANG Xiaoliang SUN Yueqiang ZHANG You LI Qifeng YU 2019Journal of Geodesy and Geoinformation Science2019,2,2:7
16Model predictions for behaviors of sand-nonplastic-fines mixtures using equivalent-skeleton void-ratio state index显示文摘It is a challenge to suggest a constitutive model for describing the stress-strain behavior of sand-fines mixtures due to that these granular mixtures exhibited very complex behaviors at different densities, pressures and fines contents. In this study, an elastoplastic constitutive model within the framework of the bounding surface plasticity and critical state theories was proposed for sand-nonplastic-fines mixtures by using the concept of the equivalent-skeleton void ratio and equivalent-skeleton void-ratio state index. The proposed model with a set of material constants calibrated from a few tests could be used to model the fines-dependent and state-dependent behaviors of the sand-nonplastic-fines mixture including the strain- softening and volumetric-expansion behaviors in the drained triaxial compression tests, and also the effects of fines content on the critical state lines in both the deviatoric stress versus mean effective stress and the void ratio versus mean effective stress planes.XIAO Yang SUN YiFei LIU HanLong XIANG Jia MA QiFeng LONG LeiHang 2017Science China(Technological Sciences)2017,60,6:7
17World’s first spaceflight on-orbit demonstration of a flexible solar array system based on shape memory polymer composites显示文摘With a 10%reversible compressive strain in more than 10 deformation cycles,the shape memory polymer composites(SMPCs)could be used for deployable structure and releasing mechanism.In this paper,without traditional electro-explosive devices or motors/controllers,the deployable SMPC flexible solar array system(SMPC-FSAS)is studied,developed,ground-based tested,and finally on-orbit validated.The epoxy-based SMPC is used for the rolling-out variable-stiffness beams as a structural frame as well as an actuator for the flexible blanket solar array.The releasing mechanism is primarily made of the cyanate-based SMPC,which has a high locking stiffness to withstand 50 g gravitational acceleration and a large unlocking displacement of 10 mm.The systematical mechanical and thermal qualification tests of the SMPC-FSAS flight hardware were performed,including sinusoidal sweeping vibration,shocking,acceleration,thermal equilibrium,thermal vacuum cycling,and thermal cycling test.The locking function of the SMPC releasing mechanisms was in normal when launching aboard the SJ20 Geostationary Satellite on 27 Dec.,2019.The SMPC-FSAS flight hardware successfully unlocked and deployed on 5 Jan.,2020 on geostationary orbit.The triggering signal of limit switches returned to ground at the 139 s upon heating,which indicated the successful unlocking function of SMPC releasing mechanisms.A pair of epoxy-based SMPC rolled variable-stiffness tubes,which clapped the flexible blanket solar array,slowly deployed and finally approached an approximate 100%shape recovery ratio within 60 s upon heating.The study and on-orbit successful validation of the SMPC-FSAS flight hardware could accelerate the related study and associated productions to be used for the next-generation releasing mechanisms as well as space deployable structures,such as new releasing mechanisms with low-shocking,testability and reusability,and ultra-large space deployable solar arrays.LAN Xin LIU LiWu ZHANG FengHua LIU ZhengXian WANG LinLin LI QiFeng PENG Fan HAO SiDa DAI WenXu WAN Xue TANG Yong WANG Mian HAO YanYan YANG Yang YANG Cheng LIU YanJu LENG JinSong 2020Science China(Technological Sciences)2020,63,8:7
18Evaluation Indicators and Extraction Method for Pitting Corrosion of Structural Steel显示文摘A set of evaluation indicators based on corrosion ratio in theory for assessing the extent of pitting corrosion and performance reduction are proposed. In order to quantify the morphology of pitting corrosion and extract the evaluation indicators,the 3D profile data obtained by pitting morphology measurement are imported into a special written program to automatically determine the location of each corrosion pit and distill any desired data pertinent to the pitting morphology. The results show that this method seems to be effective to analyze the corroded surface and characterize the pitting morphology.Shanhua Xu Youde Wang Qifeng Xue 2015Journal of Harbin Institute of Technology(New Series)2015,22,3:7
19An area-based position and attitude estimation for unmanned aerial vehicle navigation显示文摘The paper aims to challenge non-GPS navigation problems by using visual sensors and geo-referenced images. An area-based method is proposed to estimate full navigation parameters(FNPs), including attitude, altitude and horizontal position, for unmanned aerial vehicle(UAV) navigation. Our method is composed of three main modules: geometric transfer function, local normalized sobel energy image(LNSEI) based objective function and simplex-simulated annealing(SSA) based optimization algorithm. The adoption of relatively rich scene information and LNSEI, makes it possible to yield a solution robustly even in the presence of very noisy cases, such as multi-modal and/or multi-temporal images that differ in the type of visual sensor, season, illumination, weather, and so on, and also to handle the sparsely textured regions where features are barely detected or matched. Simulation experiments using many synthetic images clearly support noise resistance and estimation accuracy, and experimental results using 2367 real images show the maximum estimation error of 5.16(meter) for horizontal position, 9.72(meter) for altitude and 0.82(degree) for attitude.LIU XiaoChun WANG Hou FU Dan YU QiFeng GUO PengYu LEI ZhiHui SHANG Yang 2015Science China(Technological Sciences)2015,58,5:7
20Recent Advances in Space-Deployable Structures in China显示文摘Deployable space structure technology is an approach used in building spacecraft,especially when realizing deployment and folding functions.Once in orbit,the structures are released from the fairing,deployed,and positioned.With the development of communication,remote-sensing,and navigation satellites,space-deployable structures have become cutting-edge research topics in space science and technology.This paper summarizes the current research status and development trend of spacedeployable structures in China,including large space mesh antennas,space solar arrays,and deployable structures and mechanisms for deep-space exploration.Critical technologies of space-deployable structures are addressed from the perspectives of deployable mechanisms,cable-membrane form-finding,dynamic analysis,reliable environmental adaptability analysis,and validation.Finally,future technology developments and trends are elucidated in the fields of mesh antennas,solar arrays,deployable mechanisms,and on-orbit adjustment,assembly,and construction.Xiaofei Ma Tuanjie Li Jingya Ma Zhiyi Wang Chuang Shi Shikun Zheng Qifeng Cui Xiao Li Fan Liu Hongwei Guo Liwu Liu Zuowei Wang Yang Li 2022Engineering2022,,10:6
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