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| 1 | Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery?显示文摘Indocyanine green(ICG) kinetics(PDR/R15) used to quantitatively assess hepatic function in the perioperative period of major resective surgery and liver transplantation have been the object of an extensive, updated and critical review. New, non invasive bedside monitors(pulse dye densitometry technology) make this opportunity widely available in clinical practice. After having reviewed basic concepts of hepatic clearance, we analysed the most common indications ICG kinetic parameters have nowadays in clinical practice, focusing in particular on the diagnostic and prognostic role of PDR and R15 in the perioperative period of major liver surgery and liver transplantation. As recently pointed out, even if of extreme interest, ICG clearance parameters have still some limitations, to be considered when using these tests. | Andrea De Gasperi Ernestina Mazza Manlio Prosperi | 2016 | World Journal of Hepatology2016，8，7： | 22 |
| 2 | The impact of extent of pancreatic and venous resection on survival for patients with pancreatic cancer显示文摘Background:Borderline resectable pancreatic cancer may require extended resections in order to achieve tumor-free margins,especially in the case of up-front resections,but it is important to know the limits of surgical therapy in this disease.This study aimed to investigate the impact of extent of pancreatic and venous resection on short-and long-term outcomes in patients with pancreatic adenocarcinoma(PDAC).Methods:This was a retrospective study from a prospectively maintained database of pancreatic resections for PDAC.Short-and long-term outcomes were analyzed in patients having borderline resectable PDAC submitted to up-front total pancreatectomy(TP)or pancreaticoduodenectomy(PD)with simultaneous portal vein(PV)and/or superior mesenteric vein(SMV)resection.Venous resections were carried out as tangential venous resection(TVR)or segmental venous resection(SVR).Patients were divided into 4 groups:(1)PD+TVR,(2)PD+SVR,(3)TP+TVR,(4)TP+SVR.Uni-and multivariate Cox regression analysis were performed to identify factors associated with survival.Results:Ninety-nine patients were submitted to simultaneous pancreatic and venous resection for PDAC.Among them,25 were submitted to PD+TVR(25.3%),12 to PD+SVR(12.1%),23 to TP+TVR(23.2%),and 39 to TP+SVR(39.4%).Overall,major morbidity(Clavien-Dindo grade≥IIIA)was 26.3%.Thirty-and 90-day mortality were 3%and 11.1%,respectively.There were no significant differences among groups in terms of short-term outcomes.Median overall survival of patients submitted to PD+TVR was significantly higher than those to TP+SVR(29.5 vs 7.9 months,P=0.001).Multivariate analysis identified TP(HR=2.11;95%CI:1.31–3.44;P=0.002)and SVR(HR=2.01;95%CI:1.27–3.15;P=0.003)as the only independent prognostic factors for overall survival.Conclusions:Up-front TP associated to SVR was predictive of worse survival in borderline resectable PDAC.Perioperative treatments in high-risk surgical groups may improve such poor outcomes. | Matteo Serenari Giorgio Ercolani Alessandro Cucchetti Matteo Zanello Enrico Prosperi Guido Fallani Michele Masetti Raffaele Lombardi Matteo Cescon Elio Jovine | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，4： | 2 |
| 3 | Acute Liver Failure: Managing Coagulopathy and the Bleeding Diathesis显示文摘 | A. De Gasperi A. Corti E. Mazza M. Prosperi O. Amici L. Bettinelli | 2009 | Transplantation Proceedings2009，，4： | 1 |
| 4 | Immunocytometric determination of the alpha and beta isoforms of human DNA topoisomerase Ⅱ: influence of different fixatives显示文摘 | Prosperi E Negri C Bottiroli G | 1996 | Anal Cell Pathol1996，10，2： | 1 |
| 5 | The SARS-like coronaviruses: The role of bats and evolutionary relationships with SARS coronavirus显示文摘 | Balboni A Battilani M Prosperi S | 2012 | New Microbiol2012，35，1： | 1 |
| 6 | Beta-amyloid- induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway显示文摘 | Giovannini MG Scali C Prosperi C | 2002 | Neurobiol Dis2002，11，2： | 1 |
| 7 | Domestication history in the Medicago sativa species com- plex: inferences from nuclear sequence polymorphism显示文摘 | Muller M H Poncet C Prosperi J M Santoni S Ronfort J | 2006 | Molecular Ecology2006，15，15： | 1 |
| 8 | Effect of surface treatments on tensile bond strength and on morphology of quartz-fiber posts显示文摘 | D'Arcangelo C D'Amario M Prosperi GD | 2007 | J Endod2007，33，3： | 1 |
| 9 | Evolution of An nual Species of the Genus Medicago:A Molecular Phylogenetic Approach显示文摘 | Prosperi J Bernard L Olivieri I | 1998 | Molecular Phylogenetics and Evolution1998，9，3： | 1 |
| 10 | Ape mutation en- hances PyMT-indueed mammary tumorigenesis 显示文摘 | Prosperi JR Khramtsov AI Khramtsova GF | 2011 | PLoS One2011，6，29： | 1 |
| 11 | Multiple primary neoplasms considerations on 42 cases显示文摘 | Prosperi Porta R Lalle M Palazzetti PL | 1995 | Eur Gynaecol Oncol1995，16，6： | 1 |
| 12 | Acute thrombosis of the superior mesenteric artery in a 39-year-old woman with protein-S deficiency:a case report显示文摘 | Romano N Prosperi V Basili G | 2011 | J Med Case Rep2011，，： | 1 |
| 13 | Beta-amyloid-induced inflammation andcholinergic hypofunction in the rat brain in vivo:involvement of the p38MAPK pathway显示文摘 | Giovannini MG Scali C Prosperi C | 2002 | Neurobiol Dis2002，11，2： | 1 |
| 14 | The SARS-like coronavi- ruses: the role of bats and evolutionary relationships with SARS coronavirus显示文摘 | Balboni A Battilani M Prosperi S | 2012 | New Microbiol2012，35，1： | 1 |
| 15 | Experimental brain inflammation and ncurodegeneration as model of Alzhcimcr's disease: protective effects of selective COX-2 inhibitors 显示文摘 | Giovannini MG Scali C Prosperi C | 2003 | Int J Immunopathol Pharmacol2003，16，2： | 1 |
| 16 | Differentiation between natural and cultivated populations of Medi- cago sativa (Leguminosae) from Spain Analysis with random amplified polymorphic DNA (RAPD) mark- ers and comparison to allozymes显示文摘 | J enczewski E Prosperi J M Ronfort J | 1999 | Molecular Ecolo- gy1999，8，： | 1 |
| 17 | Effect of surface treatments on tensile bond strength and on morphology of quartz-fiber posts显示文摘 | D'Arcangelo C D'Amario M Prosperi GD | 2007 | J Endod2007，33，3： | 1 |
| 18 | Multiple Effects of Berberine Derivatives on Colon Cancer Cells显示文摘 | Luis Miguel Guamán Ortiz Micol Tillhon Michael Parks Ilaria Dutto Ennio Prosperi Monica Savio Andrea G. Arcamone Franco Buzzetti Paolo Lombardi Anna Ivana Scovassi Steve Winder | 2014 | BioMed Research International2014，，： | 1 |
| 19 | High level of polymorphism and spatial structure in a selfing plant species Medicago truncatula Gaertn using RAPDs markers显示文摘 | Huguet T Ghérardi M Prosperi J M Olivieri I | 1996 | American J of Botany1996，83，： | 1 |
| 20 | Early effects of AZT on mitochondrial functions in the absence of mitochondrial DNA depletion in rat myotubes显示文摘 | Cazzalini O Lazze M C Iamele L Stivala L A Bianchi L Vaghi P Cornaglia A Calligaro A Curti D Alessandrini A Prosperi E Vannini V | 2001 | Biochem Pharmacol2001，62，7： | 1 |
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