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| 1 | Surgical vs percutaneous radiofrequency ablation for hepatocellular carcinoma in dangerous locations显示文摘AIM:To compare the long-term outcome of percutaneous vs surgical radiofrequency ablation(RFA) for hepatocellular carcinoma(HCC) in dangerous locations.METHODS:One hundred and sixty-two patients with HCC in dangerous locations treated with percutaneous or surgical RFA were enrolled in this study.The patients were divided into percutaneous RFA group and surgical RFA group.After the patients were regularly followed up for a long time,their curative rate,hospital stay time,postoperative complications and 5-year local tumor progression were compared and analyzed.RESULTS:No significant difference was observed in curative rate between the two groups(91.3% vs 96.8%,P = 0.841).The hospital stay time was longer and more analgesics were required while the incidence of bile duct injury and RFA-related hemorrhage was lower in surgical RFA group than in percutaneous RFA group(P < 0.05).The local progression rate of HCC in dangerous locations was significantly lower in surgical RFA group than in percutaneous RFA group(P = 0.05).The relative risk of local tumor progression was 14.315 in percutaneous RFA group.CONCLUSION:The incidence of severe postoperative complications and local tumor progression is lower after surgical RFA than after percutaneous RFA. | Ji-Wei Huang Roberto Hernandez-Alejandro Kristopher P Croome Lu-Nan Yan Hong Wu Zhe-Yu Chen Pankaj Prasoon Yong Zeng | 2011 | World Journal of Gastroenterology2011，17，1： | 14 |
| 2 | Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: A meta-analysis显示文摘AIM: To determine whether the outcomes of laparoscopic fenestration (LF) were superior to open fenestration (OF) for congenital liver cysts.METHODS: Comparative studies published between January 1991 and May 2010 on Medline (Ovid),Emsco,PubMed,Science Direct;Cochrane Reviews;CNKI;Chinese Biomedical Database,VIP and other electronic databases were searched.Randomized controlled trials (RCTs) and retrospective case-control studies on the management of congenital hepatic cysts were collected according to the pre-determined eligibility criteria to establish a literature database.Retrieval was ended in May 2010.Meta-analysis was performed using RevMan 5.0 software (Cochrane library).RESULTS: Nine retrospective case-control studies involving 657 patients,comparing LF with OF were included for the final pooled analysis.The meta-analysis results showed less operative time [mean difference (MD): -28.76,95% CI: -31.03 to 26.49,P < 0.00001];shorter hospital stay (MD: -3.35,95% CI: -4.46 to -2.24,P < 0.00001);less intraoperative blood loss (MD: -40.18,95% CI: -52.54 to -27.82,P < 0.00001);earlier return to regular diet (MD: -29.19,95% CI: -30.65 to -27.72,P < 0.00001) and activities after operation (MD: -21.85,95% CI: -31.18 to -12.51,P < 0.0001) in LF group;there was no significant difference between the two groups in postoperative complications (odds ratio: 0.99,95% CI: 0.41 to 2.38,P = 0.98) and cysts recurrence rates.CONCLUSION: The short-term outcomes of LF for patients with congenital hepatic cysts were superior to open approach,but its long-term outcomes should be verified by further RCTs and extended follow-up. | Prasoon Pankaj | 2011 | World Journal of Gastroenterology2011，17，28： | 14 |
| 3 | Immunotherapy for hepatocellular carcinoma: From basic research to clinical use显示文摘Hepatocellular carcinoma(HCC) is a common cancer worldwide with a poor prognosis. Few strategies have been proven efficient in HCC treatment, particularly for those patients not indicated for curative resection or transplantation. Immunotherapy has been developed for decades for cancer control and is attaining more attention as a result of encouraging outcomes of new strategies such as chimeric antigen receptor T cells and immune checkpoint blockade. Right at the front of the new era of immunotherapy, we review the immunotherapy in HCC treatment, from basic research to clinical trials, covering anything from immunomodulators, tumor vaccines and adoptive immunotherapy. The mechanisms, efficacy and safety as well as the approach particulars are unveiled to assist readers to gain a concise but extensive understanding of immunotherapy of HCC. | Yu-Peng Hong Zi-Duo Li Pankaj Prasoon Qi Zhang | 2015 | World Journal of Hepatology2015，7，7： | 6 |
| 4 | Epidemiology of pelvic fractures in adults: Our experience at a tertiary hospital显示文摘Purpose: Pelvic fractures are severe injuries and are often associated with multiple system injuries, exacerbating the overall outcome. In India, the incidence of pelvic fractures is on a rise due to suboptimal roads and traffics but related literature regarding the overall epidemiology of these injuries is scarce and scanty. Our aim was to study the epidemiology of patients admitted with pelvic fractures at a level 1 trauma centre in India. Methods: A 16-month (between September 2015 and December 2016) prospective observational study was carried out on trauma patients with pelvic fractures at a level 1 trauma centre of a tertiary care hospital. Demography of patients, mechanism of injuries and complications were recorded prospectively. Results: We observed 75 patients who presented with pelvic fractures, where 56 were males and 19 were females. Mean age of the study populationwas 37.57 years. Road traffic accidents were the most common mode of injuries. Lateral compression injuries were the most common pattern. Associated injuries frequently encountered were lower extremities and acetabulum fractures, blunt abdominal trauma, urogenital injuries and head injuries. Out of the 75 patients, 52 were treated surgically and 23 were managed by conservative methods. Associated injuries of the extremities, head, abdomen and urogenital system indicated a longer hospital stay. Conclusion: Pelvic fractures, although belong to a relatively rare trauma subset, cause a high morbidity and mortality with considerable burden on the economy. Proper road safety training and driving etiquettes along with its strict implementation in true sense and spirit are the need of the hour. | Subhajit Ghosh Sameer Aggarwal Vishal Kumar Sandeep Patel Prasoon Kumar | 2019 | Chinese Journal of Traumatology2019，22，3： | 5 |
| 5 | Synchronous intraoperative radiofrequency ablation for multiple liver metastasis and resection of giant solid pseudopapillary tumors of the pancreas显示文摘 | LI Jia-xin WU Hong HUANG Ji-wei Pankaj Prasoon ZENG Yong | 2012 | Chinese Medical Journal2012，，9： | 5 |
| 6 | Hemi-portocaval shunt: A simple salvage maneuver for small-for-size graft during living donor liver transplantation: a case report显示文摘自从在最后几十年的生活施主肝移植(LDLT ) 的快扩大, small-for-size 症候群(SFSS ) 作为一个坚韧的问题出现了。此处, LDLT 的第一个案例在中国的大陆联合了 hemi-portocaval 分流被报导。门静脉的 overperfusion 很好被调制,接受者太平无事地恢复了。LDLT 联合了 hemi-portocaval 分流是为在 LDLT 阻止 SFSS 的一个可行过程。 | HUANG Ji-wei YAN Lu-nan CHEN Zhe-yu WU Hong LU Qiang XU Ying-long Pankaj Prasoon ZENG Yong | 2011 | Chinese Medical Journal2011，，14： | 4 |
| 7 | Laparoscopy Versus Open Distal Gastrectomy for Advanced Gastric Cancer: A Systematic Review and Meta-Analysis显示文摘 | Jianguo Qiu Prasoon Pankaj Hui Jiang Yong Zeng Hong Wu | 2013 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2013，，1： | 3 |
| 8 | QualiW of life following total hip arthroplasW in patients with acetabular fractures, previously managed by open reduction and internal fixation显示文摘 | Prasoon Kumar Ramesh Kumar Sen Vishal Kumar Ankit Dadra | 2016 | Chinese Journal of Traumatology2016，19，4： | 2 |
| 9 | Laparoscopy Versus Open Distal Gastrectomy for Advanced Gastric Cancer: A Systematic Review and Meta-Analysis显示文摘 | Jianguo Qiu Prasoon Pankaj Hui Jiang Yong Zeng Hong Wu | 2013 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2013，，1： | 2 |
| 10 | Surgical Management for Giant liver Hemangiomas Greater Than 20 cm in Size 显示文摘 | Jiang H Chen Z Prasoon P | 2011 | Gut Liver2011，5，2： | 1 |
| 11 | Utility of transbronchial needle aspiration in the diagnosis of endobronchial lesions显示文摘 | Asok D Prasoon J Omar A M | 1999 | Chest1999，115，5： | 1 |
| 12 | A meta-analysis of perioperative outcomes of laparoscopic splenectomy for hematological disorders显示文摘 | Bai YN Jiang H Prasoon P | 2012 | World J Surg2012，36，10： | 1 |
| 13 | Establishing the need to model the actual state of stress along rock bolts显示文摘Proper design of rock bolt support in underground mines is critical to avoid incidents, accidents and loss of production. The traditional design approach only considers the axial(tensile) capacity and this is clearly not the situation in situ, where a rock bolt is subjected to both axial and shear/bending loads which determines its overall performance and failure behaviour. To demonstrate and analyse the shear displacement in bedded roof, scaled physical models of underground excavation were created. From the models it was found that the shear displacement between the layers depends on the vertical roof deformation and thickness of beds. To analyse the effect of combined loading on rock bolt design for suspension and beam building models, analytical methods were used to calculate the required spacing of rock bolt for a given safety factor. Numerical models were then created using Rocscience RS2 software to establish the stresses on the rock bolt. The results show a significant reduction in safety factor for suspension as demonstrated in an example(reduced from 3.5 to 2.0) and beam building(2.0 to 1.36) when the rock bolt capacities are calculated considering the effect of combined loading as opposed to just the axial or shear loads. | Prasoon Singh AJS(Sam)Spearing K.V.Jessu Pâmmela Caroline Pinazzi da Silva Ribeiro | 2020 | International Journal of Mining Science and Technology2020，30，3： | 1 |
| 14 | Milk oligosaeeharide profiles by reversed-phase HPLC of their perbenzoylated derivatives显示文摘 | Prasoon C Christopher DW Guillermo MR | 1997 | Anal Biochem1997，251，： | 1 |
| 15 | Treatment with amisulpride and olanzapine improve neuropsychological function in schizophrenia显示文摘 | Ann M.Mortimer EileenJoyce KrishnapillaiBalasubramaniam Prasoon C.Choudhary Packeeruther T.Saleem | 2007 | Hum. Psychopharmacol. Clin. Exp2007，，7： | 1 |
| 16 | Management of Hinchey Ⅱ diverticulitis显示文摘Colonic diverticulosis can either be asymptomatic or present with complications resulting in significant morbidity and mortality.A key presentation of complicated disease is abscess formation(Hinchey type Ⅱ).The natural course of this is unclear and therefore treatments range from conservative approach with antibiotics and percutaneous guided drainage(PCD) to surgery.There is no clear consensus on the exact management strategy.A Medline based literature search specifically looking at studies dealing with Hinchey type Ⅱ diverticulitis and its management was carried out.For comparison,five-year retrospective data of diverticular abscesses from our institution was collected and the outcome analysed.Various studies have looked into this aspect of the disease,elaborating on the significance of the size and location of the abscesses,the role of PCD,recurrence rates and the controversies regarding the need for elective surgery.Conservative treatment with antibiotics alone is effective in a majority of cases with a role for PCD in large safely accessible abscesses.Variable recurrence rates have been reported in literature and elective surgery should be planned for selected groups of patients. | Soni Soumian Sudeep Thomas Prasoon P Mohan Nadia Khan Zeeshan Khan Tirumala Raju | 2008 | World Journal of Gastroenterology2008，14，47： | 1 |
| 17 | Utility of transbronchial needle aspiration in the diagnosis of endobronchial lesion 显示文摘 | Asok D Prasoon J Omar A | 1999 | Chest1999，115，3： | 1 |
| 18 | Utility of transbronchial needle aspiration in the diagnosis of endobronchial lesion显示文摘 | Asok D Prasoon J Omar A | 1999 | Chest1999，115，3： | 1 |
| 19 | ''Sandwich'' treatment for diospyrobezoar intestinal obstruction: A case report显示文摘Intestinal obstruction is a common clinical entity encountered in surgical practice.The objective of this report is to corroborate an atypical scenario of intestinal obstruction in a Chinese patient and to focus on the diagnosis and treatment.A 27-year-old male presented with a history of gastric pain combined with nausea and abdominal distension that had been present for 5 d.The presence of a foreign body was detected by computed tomography and observed as an abnormal density within the stomach.A diospyrobezoar was revealed during gastroscopy,the extraction of which was preventeddue to its size and firmness.An endoscopic holmium laser joined with a snare was used to fragment the obstruction,which was followed by management with a conservative'sandwich'treatment strategy involving intestinal decompression with an ileus tube and Coca-Cola lavage between endoscopic lithotripsy fragmentation procedures.This strategy resulted in the successful removal of the diospyrobezoar along with multiple small bowel obstructions.The patient was discharged after abatement of symptoms.The case presented here demonstrates the implementation of a conservative,yet successful,treatment as an alternative to conventional surgical removal of intestinal obstructions. | Yi-Xiong Zheng Pankaj Prasoon Yan Chen Liang Hu Li Chen | 2014 | World Journal of Gastroenterology2014，20，48： | 1 |
| 20 | Laparoscopy Versus Open Distal Gastrectomy for Advanced Gastric Cancer: A Systematic Review and Meta-Analysis显示文摘 | Jianguo Qiu Prasoon Pankaj Hui Jiang Yong Zeng Hong Wu | 2013 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2013，，1： | 1 |
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